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Clément Frainay

25
Documents
Identifiants chercheurs

Présentation

I'm a French computational biologist working on system biology and biological networks. I'm primarily interested in the study of metabolism, and I'm currently working at the [INRAE's Toxalim lab](https://www6.toulouse.inrae.fr/toxalim_eng/) on the impact of food contaminant exposure on this system. My research interests focus on solutions to overcome the information overload faced when reasoning on such large scale, leveraging network science, information filtering, information visualisation and knowledge modelling. See my page on Scholia: <https://scholia.toolforge.org/author/Q57243195>

Publications

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Suggesting disease associations for overlooked metabolites using literature from metabolic neighbors

Maxime Delmas , Olivier Filangi , Christophe Duperier , Nils Paulhe , Florence Vinson
GigaScience, 2022, 12, pp.giad065. ⟨10.1093/gigascience/giad065⟩
Article dans une revue hal-04223426v1
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Avoiding the Misuse of Pathway Analysis Tools in Environmental Metabolomics

Cecilia Wieder , Jacob Bundy , Clément Frainay , Nathalie Poupin , Pablo Rodríguez-Mier
Environmental Science and Technology, inPress, ⟨10.1021/acs.est.2c05588⟩
Article dans une revue hal-03799270v1
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Networks and Graphs Discovery in Metabolomics Data Analysis and Interpretation

Adam Amara , Clément Frainay , Fabien Jourdan , Thomas Naake , Steffen Neumann
Frontiers in Molecular Biosciences, 2022, 9, ⟨10.3389/fmolb.2022.841373⟩
Article dans une revue hal-03636716v1
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Atopic dermatitis or eczema? Consequences of ambiguity in disease name for biomedical literature mining

Clément Frainay , Yoann Pitarch , Sarah Filippi , Marina Evangelou , Adnan Custovic
Clinical and Experimental Allergy, 2021, 51 (9), pp.1185-1194. ⟨10.1111/cea.13981⟩
Article dans une revue hal-03311466v1
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FORUM: building a Knowledge Graph from public databases and scientific literature to extract associations between chemicals and diseases

Maxime Delmas , Olivier Filangi , Nils Paulhe , Florence Vinson , Christophe Duperier
Bioinformatics, 2021, 37 (21), pp.3896-3904. ⟨10.1093/bioinformatics/btab627⟩
Article dans une revue hal-03361495v1
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Pathway analysis in metabolomics: Recommendations for the use of over-representation analysis

Cecilia Wieder , Clément Frainay , Nathalie Poupin , Pablo Rodríguez-Mier , Florence Vinson
PLoS Computational Biology, 2021, 17 (9), ⟨10.1371/journal.pcbi.1009105⟩
Article dans une revue hal-03344682v1
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Large-Scale Modeling Approach Reveals Functional Metabolic Shifts during Hepatic Differentiation

Nathalie Poupin , Anne Corlu , Nicolas J. Cabaton , Hélène Dubois-Pot-Schneider , Cécile Canlet
Journal of Proteome Research, 2019, 18 (1), pp.204-216. ⟨10.1021/acs.jproteome.8b00524⟩
Article dans une revue hal-01937261v1
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MetaboRank: network-based recommendation system to interpret and enrich metabolomics results

Clément Frainay , Sandrine Aros , Maxime Chazalviel , Thomas Garcia , Florence Vinson
Bioinformatics, 2019, 35 (2), pp.274-283. ⟨10.1093/bioinformatics/bty577⟩
Article dans une revue hal-02627792v1

Integrated transcriptomics and metabolomics reveal signatures of lipid metabolism dysregulation in HepaRG liver cells exposed to PCB 126

Robin Mesnage , Martina Biserni , Sucharitha Balu , Clément Frainay , Nathalie Poupin
Archives of Toxicology, 2018, 92 (8), pp.2533-2547. ⟨10.1007/s00204-018-2235-7⟩
Article dans une revue hal-02621552v1
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MetExploreViz: web component for interactive metabolic network visualization

Maxime Chazalviel , Clément Frainay , Nathalie Poupin , Florence Vinson , Benjamin Merlet
Bioinformatics, 2018, 34 (2), pp.312-313. ⟨10.1093/bioinformatics/btx588⟩
Article dans une revue hal-02621786v1
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Classification of pediatric asthma: from phenotype discovery to clinical practice

Ceyda Oksel , Sadia Haider , Sara Fontanella , Clément Frainay , Adnan Custovic
Frontiers in Pediatrics, 2018, 6, ⟨10.3389/fped.2018.00258⟩
Article dans une revue hal-02626193v1
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Mind the gap: mapping mass spectral databases in genome-scale metabolic networks reveals poorly covered Areas

Clément Frainay , Emma L. Schymanski , Steffen Neumann , Benjamin Merlet , Reza Mohammadi Salek
Metabolites, 2018, 8 (3), ⟨10.3390/metabo8030051⟩
Article dans une revue hal-02627086v1
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MetExplore: collaborative edition and exploration of metabolic networks

Ludovic Cottret , Clément Frainay , Maxime Chazalviel , Floréal Cabanettes , Yoann Gloaguen
Nucleic Acids Research, 2018, 46 (W1), 8 p. ⟨10.1093/nar/gky301⟩
Article dans une revue hal-01886470v1
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Targeted versus untargeted omics — the CAFSA story

Maria del Mar Amador , Benoit Colsch , Foudil Lamari , Claude Jardel , Farid Ichou
Journal of Inherited Metabolic Disease, 2018, 41 (3), pp.1-10. ⟨10.1007/s10545-017-0134-3⟩
Article dans une revue hal-01777969v1
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Machine learning to identify pairwise interactions between specific IgE antibodies and their association with asthma: A cross-sectional analysis within a population-based birth cohort

Sara Fontanella , Clément Frainay , Clare S. Murray , Angela Simpson , Adnan Custovic
PLoS Medicine, 2018, 15 (11), 22 p. ⟨10.1371/journal.pmed.1002691⟩
Article dans une revue hal-02626228v1

Computational methods to identify metabolic sub-networks based on metabolomic profiles

Clément Frainay , Fabien Jourdan
Briefings in Bioinformatics, 2017, 18 (1), pp.43-56. ⟨10.1093/bib/bbv115⟩
Article dans une revue hal-01608721v1
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A computational solution to automatically map metabolite libraries in the context of genome scale metabolic networks

Benjamin Merlet , Nils Paulhe , Florence Vinson , Clément Frainay , Maxime Chazalviel
Frontiers in Molecular Biosciences, 2016, 3, ⟨10.3389/fmolb.2016.00002⟩
Article dans une revue hal-02631089v1
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Hypoxia induces VEGF-C expression in metastatic tumor cells via a HIF-1α-independent translation-mediated mechanism

Florent Morfoisse , Anna Kuchnio , Clément Frainay , Anne Gomez-Brouchet , Marie-Bernadette Delisle
Cell Reports, 2014, 6 (1), pp.155-167. ⟨10.1016/j.celrep.2013.12.011⟩
Article dans une revue hal-02631811v1

Plant genome-scale metabolic networks

Léo Gerlin , Clément Frainay , Fabien Jourdan , Caroline Baroukh , Sylvain Prigent
Science Direct. Plant Metabolomics in full swing, 98, 2021, Advances in Botanical Research, ⟨10.1016/bs.abr.2020.09.021⟩
Chapitre d'ouvrage hal-03149497v1

Genome-scale metabolic networks

Clément Frainay , Fabien Jourdan
Metabolomics: Practical Guide to Design and Analysis, 1ère édition, Chapman and Hall, 290 p., 2019, 9781315370583. ⟨10.1201/9781315370583-8⟩
Chapitre d'ouvrage hal-02786295v1