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Generation of an induced pluripotent stem cell line (ITXi012-A) from a patient with genetically determined high-lipoprotein(a) plasma levels
Amandine Caillaud
,
Lise Bray
,
Aurore Girardeau
,
Zoé Begué-Racapé
,
Lucie Vince
Article dans une revue
hal-04212298v1
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LDL lowering effect of PCSK9 inhibition is reduced in women
Veronika Myasoedova
,
Antoine Rimbert
,
Marina Camera
,
Cedric Le May
,
Romain Capoulade
Article dans une revue
hal-04212334v1
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Identification of a Gain-of-Function LIPC Variant as a Novel Cause of Familial Combined Hypocholesterolemia
Wieneke Dijk
,
Mathilde Di-Filippo Charcosset
,
Sander Kooijman
,
Robin Van Eenige
,
Antoine Rimbert
Article dans une revue
inserm-03831077v1
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Generation of a GPR146 knockout human induced pluripotent stem cell line (ITXi001-A-1)
Lise Bray
,
Amandine Caillaud
,
Aurore Girardeau
,
Murielle Patitucci
,
Cédric Le May
Article dans une revue
hal-03869113v1
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PCSK9 deficiency results in a specific shedding of excess LDLR in female mice only: Role of hepatic cholesterol
Anna Roubtsova
,
Damien Garçon
,
Sandrine Lacoste
,
Ann Chamberland
,
Jadwiga Marcinkiewicz
Article dans une revue
hal-03869056v1
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Taste-Driven Responsiveness to Fat and Sweet Stimuli in Mouse Models of Bariatric Surgery
Aurélie Dastugue
,
Cédric Le May
,
Séverine Ledoux
,
Cindy Le Bourgot
,
Pascaline Delaby
Biomedicines, 2022, Special Issue Animal Models of Human Pathology: Revision, Relevance and Refinements, 10 (4), pp.741. ⟨10.3390/biomedicines10040741⟩
Article dans une revue
hal-03869074v1
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Plasma apolipoprotein concentrations and incident diabetes in subjects with prediabetes
Mikaël Croyal
,
Matthieu Wargny
,
Kevin Chemello
,
Chloé Chevalier
,
Valentin Blanchard
Article dans une revue
hal-03869138v1
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Seipin localizes at endoplasmic-reticulum-mitochondria contact sites to control mitochondrial calcium import and metabolism in adipocytes
Yoann Combot
,
Veijo T. Salo
,
Gilliane Chadeuf
,
Maarit Hölttä
,
Katharina Ven
Article dans une revue
hal-03534214v1
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Nutritional biomarkers and heart failure requiring hospitalization in patients with type 2 diabetes: the SURDIAGENE cohort
Matthieu Wargny
,
Mikaël Croyal
,
Stéphanie Ragot
,
Elise Gand
,
David Jacobi
Article dans une revue
hal-03869068v1
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Effect of Parathyroidectomy on Metabolic Homeostasis in Primary Hyperparathyroidism
Samuel Frey
,
Raphaël Bourgade
,
Cédric Le May
,
Mikaël Croyal
,
Edith Bigot-Corbel
Article dans une revue
hal-03869109v1
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Transintestinal cholesterol excretion in health and disease
Damien Garçon
,
Jean-Matthieu Berger
,
Bertrand Cariou
,
Cédric Le May
Article dans une revue
hal-03869126v1
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Orosensory perception of fat/sweet stimuli and appetite-regulating peptides before and after sleeve gastrectomy or gastric by-pass in adult women with obesity
Arnaud Bernard
,
Johanne Le Beyec-Le Bihan
,
Loredana Radoi
,
Muriel Coupaye
,
Ouidad Sami
Article dans une revue
hal-03170655v1
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The Complex ABCG5/ABCG8 Regulates Vitamin D Absorption Rate and Contributes to its Efflux from the Intestine
Tiffany Antoine
,
Cedric Le May
,
Marielle Margier
,
Charlotte Halimi
,
Marion Nowicki
Article dans une revue
hal-03451191v1
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The Tryptophan/Kynurenine Pathway: A Novel Cross-Talk between Nutritional Obesity, Bariatric Surgery and Taste of Fat
Arnaud Bernard
,
Cédric Le May
,
Aurélie Dastugue
,
Audrey Ayer
,
Claire Blanchard
Article dans une revue
hal-03328777v1
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PCSK9 is not secreted from mature differentiated intestinal cells
François Moreau
,
Aurélie Thédrez
,
Damien Garçon
,
Audrey Ayer
,
Thibaud Sotin
Article dans une revue
hal-03350100v1
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Routine use of statins and increased COVID-19 related mortality in inpatients with type 2 diabetes: Results from the CORONADO study
Bertrand Cariou
,
Thomas Goronflot
,
Antoine Rimbert
,
Sandrine Boullu
,
Cedric Le May
Article dans une revue
hal-03100948v1
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PCSK9 regulates the NODAL signaling pathway and cellular proliferation in hiPSCs
Meryl Roudaut
,
Salam Idriss
,
Amandine Caillaud
,
Aurore Girardeau
,
Antoine Rimbert
Article dans une revue
hal-03451184v1
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Circulating PCSK9 levels are not associated with the conversion to type 2 diabetes
Stéphane Ramin-Mangata
,
Matthieu Wargny
,
Matthieu Pichelin
,
Cedric Le May
,
Aurélie Thédrez
Article dans une revue
hal-03013257v1
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VLDL (Very-Low-Density Lipoprotein)-Apo E (Apolipoprotein E) May Influence Lp(a) (Lipoprotein [a]) Synthesis or Assembly
Mikaël Croyal
,
Valentin Blanchard
,
Khadija Ouguerram
,
Maud Chétiveaux
,
Léa Cabioch
Article dans une revue
hal-03098122v1
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Circulating Rather Than Intestinal PCSK9 (Proprotein Convertase Subtilisin Kexin Type 9) Regulates Postprandial Lipemia in Mice
Damien Garçon
,
François Moreau
,
Audrey Ayer
,
Wieneke Dijk
,
Xavier Prieur
Article dans une revue
hal-03012708v1
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Roux-en-Y gastric bypass, but not sleeve gastrectomy, decreases plasma PCSK9 levels in morbidly obese patients
C. Blanchard
,
S. Ledoux
,
A. Verhaegen
,
M. Wargny
,
E. Letessier
Article dans une revue
hal-03013255v1
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Genetic Inhibition of PCSK9 and Liver Function
Antoine Rimbert
,
Sarra Smati
,
Wieneke Dijk
,
Cedric Le May
,
Bertrand Cariou
Article dans une revue
hal-03100949v1
|
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Circulating PCSK9 levels are not associated with the conversion to type 2 diabetes
Stéphane Ramin-Mangata
,
Matthieu Wargny
,
Matthieu Pichelin
,
Cédric Le May
,
Aurélie Thédrez
Article dans une revue
hal-04465329v1
|
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P-glycoprotein (ABCB1) is involved in vitamin K efflux
Marielle Margier
,
Cedric Le May
,
Tiffany Antoine
,
Charlotte Halimi
,
Marion Nowicki
Article dans une revue
hal-03012693v1
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A high-throughput mass spectrometry-based assay for large-scale profiling of circulating human apolipoproteins
Valentin Blanchard
,
Damien Garçon
,
Catherine Jaunet
,
Kevin Chemello
,
Stéphanie Billon-Crossouard
Article dans une revue
hal-03098131v1
|
|
Techniques of Sleeve Gastrectomy and Modified Roux-en-Y Gastric Bypass in Mice
Audrey Ayer
,
Frederic Borel
,
Francois Moreau
,
Xavier Prieur
,
Michel Neunlist
Journal of visualized experiments : JoVE, 2017, Equipe IV, 121, ⟨10.3791/54905⟩
Article dans une revue
hal-01832948v1
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Impact of protease inhibitors on circulating PCSK9 levels in HIV-infected antiretroviral-naive patients from an ongoing prospective cohort
Franck Boccara
,
Mathilde Ghislain
,
Laurence Meyer
,
Cecile Goujard
,
Cedric Le May
Article dans une revue
hal-01832935v1
|
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The Role of Estrogens in Pancreatic Islet Physiopathology
Franck Mauvais-Jarvis
,
Cedric Le May
,
Joseph P. Tiano
,
Suhuan Liu
,
Gamze Kilic-Berkmen
Article dans une revue
hal-01833109v1
|
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PPARγ Modulates Long Chain Fatty Acid Processing in the Intestinal Epithelium
Kalina Duszka
,
Matej Oresic
,
Cedric Le May
,
Jürgen König
,
Walter Wahli
Article dans une revue
hal-01832934v1
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Retrograde cholesterol transport in the human Caco-2/TC7 cell line: a model to study trans-intestinal cholesterol excretion in atherogenic and diabetic dyslipidemia
Camille Dugardin
,
Olivier Briand
,
Véronique Touche
,
Marleen Schonewille
,
François Moreau
Article dans une revue
hal-03013305v1
|
|
Impact of Sleeve Gastrectomy on Intestinal Permeability in Diet-Induced Obese Mice
Claire Blanchard
,
Audrey Ayer
,
Julien Chevalier
,
François Moreau
,
Jean-Paul Pais de Barros
Article dans une revue
hal-01503082v1
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FGF21 Improves the Adipocyte Dysfunction Related to Seipin Deficiency
Lucile Dollet
,
Clara Levrel
,
Tamer Coskun
,
Soazig Le Lay
,
Cedric Le May
Article dans une revue
hal-01831750v1
|
|
L’excrétion trans -intestinale de cholestérol (TICE)
Claire Blanchard
,
François Moreau
,
Bertrand Cariou
,
Cedric Le May
Article dans une revue
hal-03013320v1
|
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Preserved adrenal function in fully PCSK9-deficient subject
Bertrand Cariou
,
Isabelle Benoit
,
Cedric Le May
Article dans une revue
hal-03013322v1
|
|
Congenital Lipodystrophies and Dyslipidemias
Xavier Prieur
,
Cedric Le May
,
Jocelyne Magré
,
Bertrand Cariou
Article dans une revue
hal-03013323v1
|
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Transintestinal Cholesterol Excretion Is an Active Metabolic Process Modulated by PCSK9 and Statin Involving ABCB1
Cedric Le May
,
Jean Mathieu Berger
,
Anne Lespine
,
Bruno Pillot
,
Xavier Prieur
Article dans une revue
hal-03013326v1
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Plasma PCSK9 concentrations during an oral fat load and after short term high-fat, high-fat high-protein and high-fructose diets.
Bertrand Cariou
,
Cédric Langhi
,
Maëlle Le Bras
,
Murielle Bortolotti
,
Kim-Anne Lê
Article dans une revue
inserm-00778104v1
|
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Thiazolidinediones partially reverse the metabolic disturbances observed in Bscl2/seipin-deficient mice
X. Prieur
,
L. Dollet
,
M. Takahashi
,
M. Nemani
,
B. Pillot
Article dans une revue
hal-03013324v1
|
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Transintestinal Cholesterol Excretion Is an Active Metabolic Process Modulated by PCSK9 and Statin Involving ABCB1
Cedric Le May
,
Jean Mathieu Berger
,
Anne Lespine
,
Bruno Pillot
,
Xavier Prieur
Article dans une revue
hal-02650431v1
|
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Clinical aspects of PCSK9
Bertrand Cariou
,
Cedric Le May
,
Philippe Costet
Article dans une revue
hal-03013330v1
|
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Estrogen receptor activation reduces lipid synthesis in pancreatic islets and prevents β cell failure in rodent models of type 2 diabetes
Joseph Tiano
,
Viviane Delghingaro-Augusto
,
Cedric Le May
,
Suhuan Liu
,
Meenakshi Kaw
Article dans une revue
hal-03013329v1
|
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Extranuclear estrogen receptor- stimulates NeuroD1 binding to the insulin promoter and favors insulin synthesis
W. Wong
,
J. Tiano
,
S. Liu
,
S. Hewitt
,
Cedric Le May
Proceedings of the National Academy of Sciences of the United States of America, 2010, 107 (29), pp.13057-13062. ⟨10.1073/pnas.0914501107⟩
Article dans une revue
hal-03013333v1
|
|
Association between plasma PCSK9 and gamma-glutamyl transferase levels in diabetic patients
Bertrand Cariou
,
Maëlle Le Bras
,
Cédric Langhi
,
Cedric Le May
,
Béatrice Guyomarc’h-Delasalle
Article dans une revue
hal-03013334v1
|
|
PCSK9 is expressed in pancreatic δ-cells and does not alter insulin secretion
Cédric Langhi
,
Cedric Le May
,
Valéry Gmyr
,
Brigitte Vandewalle
,
Julie Kerr-Conte
Article dans une revue
hal-03013335v1
|
|
Proprotein Convertase Subtilisin Kexin Type 9 Null Mice Are Protected From Postprandial Triglyceridemia
Cedric Le May
,
Cédric Le May
,
Sanae Kourimate
,
Cédric Langhi
,
Maud Chétiveaux
Article dans une revue
hal-03013340v1
|
|
Importance of Extranuclear Estrogen Receptor- and Membrane G Protein-Coupled Estrogen Receptor in Pancreatic Islet Survival
S. Liu
,
Cedric Le May
,
W. P.S. Wong
,
R. Ward
,
D. Clegg
Article dans une revue
hal-03013339v1
|
|
Proprotein convertase subtilisin kexin type 9 null mice are protected from postprandial triglyceridemia
Cedric Le May
,
Sanae Kourimate
,
Cédric Langhi
,
Maud Chétiveaux
,
Anne Jarry
Article dans une revue
hal-02661775v1
|
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PCSK9 Dominant Negative Mutant Results in Increased LDL Catabolic Rate and Familial Hypobetalipoproteinemia
Cedric Le May
,
Bertrand Cariou
,
Khadija Ouguerram
,
Yassine Zaïr
,
Raphael Guerois
Article dans une revue
hal-03013337v1
|
|
Activation of the farnesoid X receptor represses PCSK9 expression in human hepatocytes
Cédric Langhi
,
Cedric Le May
,
Sanae Kourimate
,
Sandrine Caron
,
Bart Staels
Article dans une revue
hal-03013345v1
|
|
Involvement of ZIP/p62 in the regulation of PPARα transcriptional activity by p38-MAPK
Claire Diradourian
,
Cedric Le May
,
Michèle Caüzac
,
Jean Girard
,
Anne-Françoise Burnol
Article dans une revue
hal-03013344v1
|
|
Dual Mechanisms for the Fibrate-mediated Repression of Proprotein Convertase Subtilisin/Kexin Type 9
Sanae Kourimate
,
Cedric Le May
,
Cédric Langhi
,
Anne Laure Jarnoux
,
Khadija Ouguerram
Article dans une revue
hal-03013347v1
|
|
Estrogens protect pancreatic beta-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice
Cedric Le May
,
K. Chu
,
M. Hu
,
C. Ortega
,
E. Simpson
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (24), pp.9232-9237. ⟨10.1073/pnas.0602956103⟩
Article dans une revue
hal-03013348v1
|
|
Fatty Acids Induce L-CPT I Gene Expression through a PPARα-Independent Mechanism in Rat Hepatoma Cells
Cedric Le May
,
Cédric Le May
,
Michèle Caüzac
,
Claire Diradourian
,
Dominique Perdereau
Article dans une revue
hal-03013352v1
|
|
PAX4 gene variations predispose to ketosis-prone diabetes
Cedric Le May
,
Franck Mauvais-Jarvis
,
Stuart Smith
,
Cédric Le May
,
Suzanne Leal
Article dans une revue
hal-03013354v1
|
|
Antidiabetic actions of estrogen: Insight from human and genetic mouse models
Cedric Le May
,
Jean-Francois Louet
,
Cedric Lemay
,
Franck Mauvais-Jarvis
Article dans une revue
hal-03013357v1
|
|
Control of Gene Expression by Fatty Acids
Cedric Le May
,
Jean-Paul Pégorier
,
Cédric Le May
,
Jean Girard
Article dans une revue
hal-03013355v1
|
|
Regulation of liver carnitine palmitoyltransferase I gene expression by hormones and fatty acids
J.-F. Louet
,
Cedric Le May
,
J.-P. Pégorier
,
J.-F. Decaux
,
J. Girard
Article dans une revue
hal-03013360v1
|
|
Reduced hepatic fatty acid oxidation in fasting PPARα null mice is due to impaired mitochondrial hydroxymethylglutaryl-CoA synthase gene expression
Cedric Le May
,
Thierry Pineau
,
Karine Bigot
,
Claude Kohl
,
Jean Girard
Article dans une revue
hal-03013361v1
|