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Missing heritability in primary osteoarthritis: the Exorhum project

Catherine Baugé , Juliette Aury-Landas , Sylvain Leclercq , Christian Marcelli , Karim Boumediene
The european human genetics conference 2015, Jun 2015, Glasgow, United Kingdom
Poster de conférence hal-01149680v1

Epigenetic therapy: a treatment for chondrosarcoma ?

Nicolas Girard , Céline Bazille , Eva Lhuissier , Hervé Benateau , Karim Boumediene , et al.
14th FEBS Young Scientists' Forum, Aug 2014, Paris, France
Communication dans un congrès hal-01149665v1
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3-Deazaneplanocin A (DZNep), an inhibitor of the histone methyltransferase EZH2, induces apoptosis and reduces cell migration in chondrosarcoma cells

Nicolas Girard , Céline Bazille , Eva Lhuissier , Hervé Benateau , Antonio Llombart-Bosch , et al.
PLoS ONE, 2014, 9 (5), pp.e98176. ⟨10.1371/journal.pone.0098176⟩
Article dans une revue hal-01147783v1
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Anti-inflammatory and chondroprotective effects of the S-adenosylhomocysteine hydrolase inhibitor 3-Deazaneplanocin A, in human articular chondrocytes

Juliette Aury-Landas , Céline Bazille , Lyess Allas , Sara Bouhout , Christophe Chesneau , et al.
Scientific Reports, 2017, 7, pp.6483. ⟨10.1038/s41598-017-06913-6⟩
Article dans une revue hal-01569499v1
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Use of Adult Stem Cells for Cartilage Tissue Engineering: Current Status and Future Developments

Catherine Baugé , Karim Boumediene
Stem Cells International, 2015, 2015 (2015), pp.438026. ⟨10.1155/2015/438026⟩
Article dans une revue hal-01354103v1
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Cell-penetrating, antioxidant SELENOT mimetic protects dopaminergic neurons and ameliorates motor dysfunction in Parkinson's disease animal models

Ifat Alsharif , Loubna Boukhzar , Benjamin Lefranc , David Godefroy , Juliette Aury-Landas , et al.
Redox Biology, 2021, 40, pp.101839. ⟨10.1016/j.redox.2020.101839⟩
Article dans une revue hal-03132187v1

Comparative study of the sensibility of chondrosarcoma to DNA damaging agents

Nicolas Girard , Eva Lhuissier , Olivier Cauvard , A. Batalla , Céline Bazille , et al.
FEBS-EMBO 2014 congress, Aug 2014, Paris, France
Poster de conférence hal-01149694v1

3-deazaneplanocin A (DZNep), an inhibitor of histone methyltransferase EZH2, induces apoptosis and reduces cell migration in chondrosarcoma cells.

Nicolas Girard , Céline Bazille , Eva Lhuissier , Hervé Benateau , Antonio Llombart-Bosch , et al.
23rd biennial congress of the european association for cancer research, Jul 2014, Munich, Germany
Poster de conférence hal-01149710v1
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Evaluation of the impact of S-adenosylmethionine-dependent methyltransferase inhibitor, 3-deazaneplanocin A, on tissue injury and cognitive function in mice

Eva Lhuissier , Juliette Aury-Landas , Valentine Bouët , Céline Bazille , Yohann Repesse , et al.
Oncotarget, 2018, 9 (29), pp.20698 - 20708. ⟨10.18632/oncotarget.25062⟩
Article dans une revue hal-01796395v1
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Type II TGFβ receptor modulates chondrocyte phenotype

Catherine Baugé , Elise Duval , David Ollitrault , Nicolas Girard , Sylvain Leclercq , et al.
AGE, 2013, 35 (4), pp.1105-16. ⟨10.1007/s11357-012-9433-7⟩
Article dans une revue hal-01149519v1
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TOL19-001 reduces inflammation and MMP expression in monolayer cultures of tendon cells

Catherine Baugé , Sylvain Leclercq , Thierry Conrozier , Karim Boumediene
BMC Complementary and Alternative Medicine, 2014, 15 (1), pp.217. ⟨10.1186/s12906-015-0748-7⟩
Article dans une revue hal-01175679v1

Modulation of Skin Inflammatory Response by Active Components of Silymarin

Jana Juráňová , Juliette Aury-Landas , Karim Boumediene , Catherine Baugé , David Biedermann , et al.
Molecules, 2019, 24 (1), pp.123. ⟨10.3390/molecules24010123⟩
Article dans une revue hal-02094235v1
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EZH2 inhibition reduces cartilage loss and functional impairment related to osteoarthritis

Lyess Allas , Sybille Brochard , Quitterie Rochoux , Jules Ribet , Cleo Dujarrier , et al.
Scientific Reports, 2020, 10 (1), pp.19577. ⟨10.1038/s41598-020-76724-9⟩
Article dans une revue hal-03003543v1
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The benefit of combining curcumin, bromelain and harpagophytum to reduce inflammation in osteoarthritic synovial cells

Sybille Brochard , Julien Pontin , Benoit Bernay , Karim Boumediene , Thierry Conrozier , et al.
BMC Complementary Medicine and Therapies, 2021, 21 (1), pp.261. ⟨10.1186/s12906-021-03435-7⟩
Article dans une revue hal-03503305v1
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Asporin expression is highly regulated in human chondrocytes

Elise Duval , Nicolas Bigot , Magalie Hervieu , Ikuyo Kou , Sylvain Leclercq , et al.
Molecular Medicine, 2010, 17 (7-8), pp.816-23. ⟨10.2119/molmed.2011.00052⟩
Article dans une revue hal-01149586v1
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Co-Treatment with the Epigenetic Drug, 3-Deazaneplanocin A (DZNep) and Cisplatin after DZNep Priming Enhances the Response to Platinum-Based Therapy in Chondrosarcomas

Eva Lhuissier , Juliette Aury-Landas , Marion Lenté , Karim Boumediene , Catherine Baugé
Cancers, 2021, 13 (18), pp.4648. ⟨10.3390/cancers13184648⟩
Article dans une revue hal-03503309v1
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Antiproliferative effect of the histone demethylase inhibitor GSK-J4 in chondrosarcomas

Eva Lhuissier , Juliette Aury-Landas , Lyess Allas , Martine Boittin , Karim Boumediene , et al.
IUBMB Life, 2019, pp.1711-1719. ⟨10.1002/iub.2110⟩
Article dans une revue hal-02168876v1
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Heterogeneity of chondrosarcomas response to irradiations with X-rays and carbon ions: A comparative study on five cell lines

Nicolas Girard , Eva Lhuissier , Juliette Aury-Landas , Olivier Cauvard , Marion Lente , et al.
Journal of Bone Oncology, 2020, 22, pp.100283. ⟨10.1016/j.jbo.2020.100283⟩
Article dans une revue hal-02515437v1

Bénéfice d'un copolymère injectable d'acides gras dans le traitement des maladies articulaires

Catherine Baugé , Gérard Ewert , Juliette Aury-Landas , Marion Berthelot , Karim Boumediene , et al.
Le Point vétérinaire (Éd. Expert canin), 2017, 372
Article dans une revue hal-01569501v1
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Epigenetic dynamic during endochondral ossification and articular cartilage development

Lyess Allas , Karim Boumediene , Catherine Baugé
BONE, 2018, pp.523-532. ⟨10.1016/j.bone.2018.10.004⟩
Article dans une revue hal-01898175v1
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Histone methylases as novel drug targets: developing inhibitors of EZH2

Catherine Baugé , Céline Bazille , Nicolas Girard , Eva Lhuissier , Karim Boumediene
Future Medicinal Chemistry, 2013, 6 (17), pp.1943-65. ⟨10.4155/fmc.14.123⟩
Article dans une revue hal-01147761v1
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Regulatory mechanism of transforming growth factor beta receptor type II degradation by interleukin-1 in primary chondrocytes

Catherine Baugé , Nicolas Girard , Sylvain Leclercq , Philippe Galéra , Karim Boumédiene
BBA - Biochimica et Biophysica Acta, 2012, 1823 (5), pp.983-6. ⟨10.1016/j.bbamcr.2012.02.017⟩
Article dans une revue hal-01149560v1
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Modulation of transforming growth factor beta signalling pathway genes by transforming growth factor beta in human osteoarthritic chondrocytes: involvement of Sp1 in both early and late response cells to transforming growth factor beta

Catherine Baugé , Olivier Cauvard , Sylvain Leclercq , Philippe Galéra , Karim Boumédiene
Arthritis Research and Therapy, 2010, 13 (1), pp.R23. ⟨10.1038/sj.onc.1204808⟩
Article dans une revue hal-01149577v1

Molecular characterization of commonly used chondrosarcoma cell lines

Juliette Aury-Landas , Morgane Barreau , Nicolas Girard , Eva Lhuissier , Karim Boumediene , et al.
The european human genetics conference 2015, Jun 2015, Glasgow, United Kingdom
Poster de conférence hal-01149676v1

Histone H3 Lysine 27 demethylases Jmjd3 and Utx are required for T-cell differentiation

Sugata Manna , Jong Kyong Kim , Catherine Baugé , Margaret Cam , Yongmei Zhao , et al.
Nature Communications, 2014, 6, pp.8152. ⟨10.1038/ncomms9152⟩
Article dans une revue hal-01249006v1
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Development of a simple osteoarthritis model useful to predict in vitro the anti-hypertrophic action of drugs

Lyess Allas , Quitterie Rochoux , Sylvain Leclercq , Karim Boumediene , Catherine Baugé
Laboratory Investigation, 2019, pp.64-71. ⟨10.1038/s41374-019-0303-0⟩
Article dans une revue hal-02266635v1
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Identification of an easy to use 3D culture model to investigate invasion and anticancer drug response in chondrosarcomas

Eva Lhuissier , Céline Bazille , Juliette Aury-Landas , Nicolas Girard , Julien Pontin , et al.
BMC Cancer, 2017, 17 (1), pp.490. ⟨10.1186/s12885-017-3478-z⟩
Article dans une revue hal-01569494v1

Hypoxia inducible factor 1 alpha down-regulates type i collagen through Sp3 transcription factor in human chondrocytes

Elise Duval , Mouloud Bouyoucef , Sylvain Leclercq , Catherine Baugé , Karim Boumediene
International Union of Biochemistry and Molecular Biology Life, 2016, pp.756-763. ⟨10.1002/iub.1539⟩
Article dans une revue hal-01354099v1

Comparative study of chondrosarcomas response to DNA damage. Impact of HIF2 expression

Eva Lhuissier , Nicolas Girard , Olivier Cauvard , Céline Bazille , Hervé Bénateau , et al.
23rd biennial congress of the european association for cancer research, Jul 2014, Munich, Germany
Poster de conférence hal-01149717v1

Thérapie épigénétique avec le 3-deazaneplanocin (DZNep), un inhibiteur de l'histone méthyl-tranférase EZH2, traitement futur des chondrosarcomes de haut grade ?

Céline Bazille , Nicolas Girard , Karim Boumediene , Catherine Baugé
7ème journée de la recherche, CHU de Caen, Jun 2015, Caen, France
Communication dans un congrès hal-01149723v1