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Dasatinib increases endothelial permeability leading to pleural effusion

 Carole Phan , Etienne-Marie Jutant , Ly Tu , Raphaël Thuillet , Andrei Seferian , et al.
European Respiratory Journal, 2018, 51 (1), pp.1701096. ⟨10.1183/13993003.01096-2017⟩
Article dans une revue inserm-02580192v1
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Serum and Pulmonary Uric Acid in Pulmonary Arterial Hypertension

 Laurent Savale , Satoshi Akagi , Ly Tu , Amélie Cumont , Raphaël Thuillet , et al.
European Respiratory Journal, 2021, 58 (2), pp.2000332. ⟨10.1183/13993003.00332-2020⟩
Article dans une revue inserm-03118201v1
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Selective BMP-9 Inhibition Partially Protects Against Experimental Pulmonary Hypertension

 Ly Tu , Agnes Desroches-Castan , Christine Mallet , Laurent Guyon , Amélie Cumont , et al.
Circulation Research, 2019, 124 (6), pp.846-855. ⟨10.1161/CIRCRESAHA.118.313356⟩
Article dans une revue inserm-02581297v1

Dasatinib induces lung vascular toxicity and predisposes to pulmonary hypertension

 Christophe Guignabert , Carole Phan , Andrei Seferian , Alice Huertas , Ly Tu , et al.
Journal of Clinical Investigation, 2016, 126 (9), pp.3207-3218. ⟨10.1172/JCI86249⟩
Article dans une revue inserm-02579754v1
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Increased Pericyte Coverage Mediated by Endothelial-Derived Fibroblast Growth Factor-2 and Interleukin-6 Is a Source of Smooth Muscle–Like Cells in Pulmonary Hypertension

 Nicolas Ricard , Ly Tu , Morane Le Hiress , Alice Huertas , Carole Phan , et al.
Circulation, 2014, 129 (15), pp.1586-1597. ⟨10.1161/CIRCULATIONAHA.113.007469⟩
Article dans une revue inserm-02578269v1

Vers de nouvelles cibles pour le traitement de l’hypertension artérielle pulmonaire : Importance des communications cellulaires

 Ly Tu , Maria-Rosa Ghigna , Carole Phan , Jennifer Bordenave , Morane Le Hiress , et al.
Biologie Aujourd'hui, 2016, 210 (2), pp.65-78. ⟨10.1051/jbio/2016010⟩
Article dans une revue inserm-02579962v1
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Neutralization of CXCL12 attenuates established pulmonary hypertension in rats Short Title: CXCL12 neutraligands in severe PH in the rat

 Jennifer Bordenave , Raphaël Thuillet , Ly Tu , Carole Phan , Amélie Cumont , et al.
Cardiovascular Research, In press, pp.cvz153. ⟨10.1093/cvr/cvz153⟩
Article dans une revue hal-02195697v1
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Etude des effets indésirables pulmonaires associés à la prise de dasatinib : Rôle de la perturbation des fonctions de l’endothélium pulmonaire

 Carole Phan
Biologie moléculaire. Université Paris Saclay (COmUE), 2018. Français. ⟨NNT : 2018SACLS345⟩
Thèse tel-03917465v1

[IL6R is the key therapeutical target in pulmonary arterial hypertension]

 Ly Tu , Carole Phan , Marc Humbert , Christophe Guignabert
Médecine/Sciences, 2018, 34 (10), pp.765-768. ⟨10.1051/medsci/2018201⟩
Article dans une revue inserm-02580983v1

Ectopic upregulation of membrane-bound IL6R drives vascular remodeling in pulmonary arterial hypertension

 Yuichi Tamura , Carole Phan , Ly Tu , Morane Le Hiress , Raphaël Thuillet , et al.
Journal of Clinical Investigation, 2018, 128 (5), pp.1956-1970. ⟨10.1172/JCI96462⟩
Article dans une revue inserm-02580448v1
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Switching-Off Adora2b in Vascular Smooth Muscle Cells Halts the Development of Pulmonary Hypertension

 Tinne Mertens , Ankit Hanmandlu , Ly Tu , Carole Phan , Scott Collum , et al.
Frontiers in Physiology, 2018, 9, pp.555. ⟨10.3389/fphys.2018.00555⟩
Article dans une revue inserm-02580921v1

Role of Nerve Growth Factor in Development and Persistence of Experimental Pulmonary Hypertension

 Véronique Freund-Michel , Marcelina Cardoso dos Santos , Christophe Guignabert , David Montani , Carole Phan , et al.
American Journal of Respiratory and Critical Care Medicine, 2015, 192 (3), pp.342-355. ⟨10.1164/rccm.201410-1851OC⟩
Article dans une revue inserm-02578672v1

Functional interaction between PDGFβ and GluN2B-containing NMDA receptors in smooth muscle cell proliferation and migration in pulmonary arterial hypertension

 Marceau Quatredeniers , K Nakhleh Morad , J Dumas Sebastien , Audrey Courboulin , C Vinhas Maria , et al.
American Journal of Physiology - Lung Cellular and Molecular Physiology, 2019, 316 (3), pp.L445-L455. ⟨10.1152/ajplung.00537.2017⟩
Article dans une revue hal-02411597v1

Leptin signalling system as a target for pulmonary arterial hypertension therapy

 Alice Huertas , Ly Tu , Raphaël Thuillet , Morane Le Hiress , Carole Phan , et al.
European Respiratory Journal, 2015, 45 (4), pp.1066-1080. ⟨10.1183/09031936.00193014⟩
Article dans une revue inserm-02579431v1

Design, Synthesis, and Biological Activity of New N -(Phenylmethyl)-benzoxazol-2-thiones as Macrophage Migration Inhibitory Factor (MIF) Antagonists: Efficacies in Experimental Pulmonary Hypertension

 Morane Le Hiress , Bernardin Akagah , Guillaume Bernadat , Ly Tu , Raphaël Thuillet , et al.
Journal of Medicinal Chemistry, 2018, 61 (7), pp.2725-2736. ⟨10.1021/acs.jmedchem.7b01312⟩
Article dans une revue inserm-02580381v1
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Therapeutic effect of pirfenidone in the sugen/hypoxia rat model of severe pulmonary hypertension

 Paul-Benoit Poble , Carole Phan , Timothée Quatremare , Jennifer Bordenave , Raphaël Thuillet , et al.
FASEB Journal, 2018, 33 (3), pp.3670-3679. ⟨10.1096/fj.201801659R⟩
Article dans une revue inserm-02581079v1
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Proinflammatory Signature of the Dysfunctional Endothelium in Pulmonary Hypertension. Role of the Macrophage Migration Inhibitory Factor/CD74 Complex

 Morane Le Hiress , Ly Tu , Nicolas Ricard , Carole Phan , Raphaël Thuillet , et al.
American Journal of Respiratory and Critical Care Medicine, 2015, 192 (8), pp.983-997. ⟨10.1164/rccm.201402-0322OC⟩
Article dans une revue inserm-02579320v1
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Regulatory T Cell Dysfunction in Idiopathic, Heritable and Connective Tissue-Associated Pulmonary Arterial Hypertension

 Alice Huertas , Carole Phan , Jennifer Bordenave , Ly Tu , Raphaël Thuillet , et al.
Chest, 2016, 149 (6), pp.1482-1493. ⟨10.1016/j.chest.2016.01.004⟩
Article dans une revue inserm-02593143v1
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