Recherche - Archive ouverte HAL Accéder directement au contenu

Filtrer vos résultats

34 résultats
Image document

Editing a γ-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype

Leslie Weber , Giacomo Frati , Tristan Felix , Giulia Hardouin , Antonio Casini , et al.
Science Advances , 2020, 6 (7), pp.eaay9392. ⟨10.1126/sciadv.aay9392⟩
Article dans une revue mnhn-03100446v1
Image document

Gene targeting in rats using transcription activator-like effector nucleases

Séverine Ménoret , Laurent Tesson , Severine Rémy , Claire Usal , Virginie Thépenier , et al.
Methods, 2014, 69 (1), pp.102-107. ⟨10.1016/j.ymeth.2014.02.027⟩
Article dans une revue inserm-02164327v1
Image document

Efficient gene targeting by homology-directed repair in rat zygotes using TALE nucleases

Séverine Remy , Laurent Tesson , Séverine Ménoret , Claire Usal , Anne de Cian , et al.
Genome Research, 2014, 24 (8), pp.1371-1383. ⟨10.1101/gr.171538.113⟩
Article dans une revue inserm-02164405v1
Image document

Chromosomal Translocation Formation Is Sufficient to Produce Fusion Circular RNAs Specific to Patient Tumor Cells

Loelia Babin , Marion Piganeau , Benjamin Renouf , Khadija Lamribet , Cécile Thirant , et al.
iScience, 2018, 5, pp.19-29. ⟨10.1016/j.isci.2018.06.007⟩
Article dans une revue mnhn-02402034v1

Generation of Immunodeficient Rats With Rag1 and Il2rg Gene Deletions and Human Tissue Grafting Models

Séverine Menoret , Laure-Hélène Ouisse , Laurent Tesson , Frédéric Delbos , Delphine Garnier , et al.
Transplantation, 2018, 102 (8), pp.1271-1278. ⟨10.1097/TP.0000000000002251⟩
Article dans une revue mnhn-02402053v1
Image document

Unraveling Ewing Sarcoma Tumorigenesis Originating from Patient-Derived Mesenchymal Stem Cells

Anna Sole , Sandrine Grossetête , Maxime Heintzé , Loelia Babin , Sakina Zaïdi , et al.
Cancer Research, 2021, 81 (19), pp.4994-5006. ⟨10.1158/0008-5472.CAN-20-3837⟩
Article dans une revue mnhn-03873854v1

CRISPR-Cas9: A revolution in genome editing in rheumatic diseases

Isabelle Duroux-Richard , Carine Giovannangeli , Florence Apparailly
Joint Bone Spine, 2017, 84 (1), pp.1 - 4. ⟨10.1016/j.jbspin.2016.09.012⟩
Article dans une revue hal-01845048v1

Exploring the Cellular Activity of Camptothecin-Triple-Helix-Forming Oligonucleotide Conjugates.

P.B. Arimondo , C.J. Thomas , K. Oussedik , B. Baldeyrou , C. Mahieu , et al.
Molecular and Cellular Biology, 2006, 26, pp.324-333
Article dans une revue hal-00017190v1
Image document

High doses of CRISPR/Cas9 ribonucleoprotein efficiently induce gene knockout with low mosaicism in the hydrozoan Clytia hemisphaerica through microhomology-mediated deletion

Tsuyoshi R Momose , Anne de Cian , Kogiku Shiba , Kazuo Inaba , Carine Giovannangeli , et al.
Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-018-30188-0⟩
Article dans une revue hal-02142636v1
Image document

Recent Progress in Genome Editing for Gene Therapy Applications: The French Perspective

Mario Amendola , Aurélie Bedel , Ana Buj-Bello , Mathieu Carrara , Jean-Paul Concordet , et al.
Human Gene Therapy, 2021, 32 (19-20), pp.1059-1075. ⟨10.1089/hum.2021.191⟩
Article dans une revue hal-03420183v1
Image document

Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins

Séverine Ménoret , Anne de Cian , Laurent Tesson , Séverine Remy , Claire Usal , et al.
Scientific Reports, 2015, 5, pp.14410. ⟨10.1038/srep14410⟩
Article dans une revue hal-01271745v1
Image document

About the constructivist role of auto-evaluation in interactive learnings and self-development

C. Giovannangeli , Sofiane Boucenna , P. Gaussier
IROS, 2008, France
Communication dans un congrès hal-00522767v1

Triplex-forming oligonucleotide-orthophenanthroline conjugates for efficient targeted genome modification.

Fabio Cannata , Erika Brunet , Loïc Perrouault , Victoria Roig , Slimane Ait-Si-Ali , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2008, 105 (28), pp.9576-81. ⟨10.1073/pnas.0710433105⟩
Article dans une revue hal-00408029v1

Molecular basis of the targeting of topoisomerase II-mediated DNA cleavage by VP16 derivatives conjugated to triplex-forming oligonucleotides.

M. Duca , D. Guianvarc'H , K. Oussedik , L. Halby , A. Garbesi , et al.
Nucleic Acids Research, 2006, 34(6), pp.1900-1911
Article dans une revue hal-00120822v1
Image document

Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression

Panagiotis Antoniou , Giulia Hardouin , Pierre Martinucci , Giacomo Frati , Tristan Felix , et al.
Nature Communications, 2022, 13 (1), pp.6618. ⟨10.1038/s41467-022-34493-1⟩
Article dans une revue mnhn-03868573v1
Image document

Disease modeling by efficient genome editing using a near PAM-less base editor in vivo

Marion Rosello , Malo Serafini , Luca Mignani , Dario Finazzi , Carine Giovannangeli , et al.
Nature Communications, 2022, 13 (1), pp.3435. ⟨10.1038/s41467-022-31172-z⟩
Article dans une revue mnhn-03868574v2
Image document

Perception: Insights from the Sensori-motor Approach

L. Hafemeister , P. Gaussier , Mickael Maillard , Sofiane Boucenna , C. Giovannangeli
EUVIP, 2010, Paris, France
Communication dans un congrès hal-00522776v1
Image document

The Xenopus tadpole: an in vivo model to screen drugs favoring remyelination

Abdelkrim Mannioui , Quentin Vauzanges , Jean Baptiste Fini , Esther Henriet , Somya Sekizar , et al.
Multiple Sclerosis Journal, 2018, 24 (11), pp.1421 - 1432. ⟨10.1177/1352458517721355⟩
Article dans une revue hal-01912256v1
Image document

De novo generation of the NPM-ALK fusion recapitulates the pleiotropic phenotypes of ALK+ ALCL pathogenesis and reveals the ROR2 receptor as target for tumor cells

Loélia Babin , Alice Darchen , Elie Robert , Zakia Aid , Rosalie Borry , et al.
Molecular Cancer, 2022, 21 (1), pp.65. ⟨10.1186/s12943-022-01520-0⟩
Article dans une revue mnhn-03868576v1
Image document

The human DNA ends proteome uncovers an unexpected entanglement of functional pathways

Vivien Berthelot , Gildas Mouta-Cardoso , Nadia Hégarat , François Guillonneau , Jean-Christophe François , et al.
Nucleic Acids Research, 2016, 44 (10), pp.4721-4733. ⟨10.1093/nar/gkw121⟩
Article dans une revue hal-01360132v1
Image document

CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair

M. Charpentier , A. H y Khedher , S. Menoret , A. Brion , K. Lamribet , et al.
Nature Communications, 2018, 9 (1), ⟨10.1038/s41467-018-03475-7⟩
Article dans une revue inserm-02156427v1

Generation of gene-edited rats by delivery of CRISPR/Cas9 protein and donor DNA into intact zygotes using electroporation

Séverine Remy , Vanessa Chenouard , Laurent Tesson , Claire Usal , Séverine Ménoret , et al.
Scientific Reports, 2017, Equipe I, 7 (1), pp.16554. ⟨10.1038/s41598-017-16328-y⟩
Article dans une revue hal-01832141v1

Genome Editing in Rats Using TALE Nucleases

Laurent Tesson , Severine Remy , Séverine Ménoret , Claire Usal , Reynald Thinard , et al.
TALENs. Methods in Molecular Biology, pp.245-259, 2016, ⟨10.1007/978-1-4939-2932-0_18⟩
Chapitre d'ouvrage inserm-02150568v1

A model of grid cells involving extra hippocampal path integration and the hippocampal loop

Ph. Gaussier , J.-P. Banquet , F. Sargolini , C. Giovannangeli , E. Save , et al.
Journal of Integrative Neuroscience, 2007, 6 (6), pp.447-476
Article dans une revue hal-00321060v1

Lipid-mediated siRNA delivery down regulates exogenous gene expression in the mouse brain at picomolar levels.?

Z. Hassani , G.F. Lemkine , P. Erbacher , G. Alfama , C. Giovannangeli , et al.
J. Gene Med., 2005, 7, pp.198-207
Article dans une revue hal-00129881v1
Image document

Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human Cells

Edwige B Garcin , Stéphanie Gon , Meghan Sullivan , Gregory J Brunette , Anne De Cian , et al.
PLoS Genetics, 2019, 15 (10), pp.e1008355. ⟨10.1371/journal.pgen.1008355⟩
Article dans une revue hal-02383639v1

Intercalator conjugates of pyrimidine locked nucleic acid-modified triplex-forming oligonucleotides: improving DNA binding properties and reaching cellular activities

E. Brunet , M. Corgnali , L. Perrouault , V. Roig , U. Asseline , et al.
Nucleic Acids Research, 2005, 33, pp.4223-4234
Article dans une revue hal-00088528v1
Image document

Generation of Rag1 and Il2rg immunodeficient rats and application to humanization studies

Séverine Ménoret , Laure-Hélène Ouisse , L. Tesson , S. Remy , Claire Usal , et al.
The 3rd IGO SUMMER MEETING, Apr 2018, Nantes, France
Poster de conférence inserm-02160389v1
Image document

A hybrid CMV-H1 construct improves efficiency of PEI-delivered shRNA in the mouse brain.

Zahra Hassani , Jean-Christophe François , Gladys Alfama , Ghislaine Morvan Dubois , Mathilde Paris , et al.
Nucleic Acids Research, 2007, 35 (9), pp.e65. ⟨10.1093/nar/gkm152⟩
Article dans une revue hal-00179406v1

Lipid-mediated siRNA delivery down-regulates exogenous gene expression in the mouse brain at picomolar levels.

Zahra Hassani , Gregory F Lemkine , Patrick Erbacher , Karima Palmier , Gladys Alfama , et al.
The Journal of Gene Medicine, 2005, 7 (2), pp.198-207. ⟨10.1002/jgm.659⟩
Article dans une revue istex hal-00181088v1