Nombre de documents

17

CV


 

Luc CAMOIN, PhD, 57

 

CURSUS

Habilitation to supervise research (HDR) at University Paris Descartes

PhD in Biochemistry at University Denis Diderot, Paris, France (Genome and Proteome)

DEA – Equivalent of a Master of Science on Organic Chemistry at Montpellier University, France

Degree in Chemistry and Chemical Engineering at the National School of Chemistry of Montpellier, France - l'Ecole Nationale Supérieure de Chimie de Montpellier ENSCM

 

FONCTIONS

Since 2010 Member of the Marseille Proteomics Facility (Centre de recherche en Cancérologie de Marseille ; CRCM, Institut Paoli Calmettes ; IPC)

2007-2009 Leader of the University Paris Descartes Proteomics Platform

2002-2007 Group Leader of the Proteomic Laboratory (Institut Cochin)

2001-2002 Codirector of the Functional Proteomic Research Team (Institut Cochin de Génétique Moléculaire, Department of Cellular Biology)

1990-2001 Group Leader of the Protein Structure Research Team in the Molecular Immuno-Pharmacology laboratory (Centre National de la Recherche Scientifique, CNRS)

1990- Research Engineer at INSERM (Institut National de la Santé et de la Recherche Médicale)

1987-1990 Research Engineer at the Pasteur Institute in Paris Responsable for creation of the protein microsequencing laboratory (3 people)

1985-1986 Assistant Engineer at the Military laboratory for the French Navy SECLF (Station d'Essais des Combustibles et Lubrifiants de la Flotte) (10 people)

1984-1985 Engineer Responsible for project at the French oil society TOTAL. Study of the use of Inductively Coupled Plasmas in analytical atomic spectrometry for metals analysis in petrochemistry

 

ACTIVITES LINKED TO SCIENTIFIC RESEARCH

Organization of a 4 days courses every 2 years for the INSERM entitled " Proteomics in all its states - An Introduction to proteomics ", since 2016, Marseille, France ( 20 people).

Organisation of one weeks courses for INSERM Introduction to proteomic tools, (2004-2010), Paris, France (20 people).

Organization of a workshop multi-institution (CNRS-INSERM-INRA) entitled "Contribution of the quantitative proteomics for the discovery of biomarkers", in June, 2014 (80 people), Sète, France.

Organisation of a 3 days courses every 2 years for INSERM  entitled « Interactome ; Biochemical and Biophysical approches », since 2011, Marseille, France (20 personnes)

Organization of a workshop multi-institution (CNRS-INSERM-INRA) "Interactomique: contributions of the mass spectrometry and proteomics", in June, 2012. La Grande-Motte, France (80 people).

Organisation of the workshop 146 for INSERM entitled Proteomic Analysis: New approaches to studying protein-protein interactions, 10-12 September 2003, La Londe-Les-Maures, Toulon, France

 

Member of the Board of the French proteomic society (2011-2017)

Member of the French committee of the pharmacopoeia - Biological products and innovative therapies (since 2014)

Member od the scientific advisory board of the “Pole Proteome de Montpellier” since 2011

 

PUBLICATIONS 78 Publications and 4 patents

 

Selected recent publications

• Activation peptide of the coagulation factor XIII (AP-F13A1) as a new biomarker for the screening of colorectal cancer (2018) Peltier, J., Roperch, J.P., Audebert, S., Borg, J.P., and Camoin, L. Clin Proteomics ; 15, 15.

• Cyclipostins and cyclophostin analogs inhibit the antigen 85C from Mycobacterium tuberculosis both in vitro and in vivo (2018) Viljoen, A., Richard, M., Nguyen, P.C., Fourquet, P., Camoin, L., Paudal, R.R., Gnawali, G.R., Spilling, C.D., Cavalier, J.F., Canaan, S., et al. J Biol Chem ; 293, 2755-2769.

• Early prognostic factors in septic shock cancer patients: a prospective study with a proteomic approach (2018) Mokart, D., Saillard, C., Zemmour, C., Bisbal, M., Sannini, A., Chow-Chine, L., Brun, J.P., Faucher, M., Boher, J.M., Toiron, Y., Chabannon, C., Borg, J. P., Goncalves, A. et Camoin, L. Acta Anaesthesiol Scand ; 62, 493-503.

• How may targeted proteomics complement genomic data in breast cancer? (2017)Guerin M, Gonçalves A, Toiron Y, Baudelet E, Audebert S, Boyer JB, Borg JP, Camoin L. Expert Rev Proteomics; 14(1):43-54.

• Fibronectin-guided migration of carcinoma collectives (2017) Gopal S, Veracini L, Grall D, Butori C, Schaub S, Audebert S, Camoin L, Baudelet E, Radwanska A, Beghelli-de la Forest Divonne S, Violette SM, Weinreb PH, Rekima S, Ilie M, Sudaka A, Hofman P, Van Obberghen-Schilling E. Nat Commun; 8:14105.

• Bonacci, T., Audebert, S., Camoin, L., Baudelet, E., Iovanna, J.L., and Soubeyran, P. (2017). Regulation of NUB1 Activity through Non-Proteolytic Mdm2-Mediated Ubiquitination. PLoS One ; 12 e0169988.

• Quantitative proteomic analysis exploring progression of colorectal cancer: Modulation of the serpin family (2016) Peltier J, Roperch JP, Audebert S, Borg JP, Camoin L. J Proteomics; 148:139-48

• The scaffolding function of the RLTPR protein explains its essential role for CD28 co-stimulation in mouse and human T cells (2016) Roncagalli R, Cucchetti M, Jarmuzynski N, Grégoire C, Bergot E, Audebert S, Baudelet E, Menoita MG, Joachim A, Durand S, Suchanek M, Fiore F, Zhang L, Liang Y, Camoin L, Malissen M, Malissen B. J Exp Med; 213(11):2437-2457.

• Identification of New Mechanisms of Cellular Response to Chemotherapy by Tracking Changes in Post-Translational Modifications by Ubiquitin and Ubiquitin-Like Proteins (2014) Bonacci T, Audebert S, Camoin L, Baudelet E, Bidaut G, Garcia M, Witzel, II, Perkins ND, Borg JP, Iovanna JL, Soubeyran P: J Proteome Res; 13(5):2478-94

• Glial-cell-mediated re-induction of the blood-brain barrier phenotype in brain capillary endothelial cells: a differential gel electrophoresis study (2013) Deracinois B, Pottiez G, Chafey P, Teerlink T, Camoin L, Davids M, Broussard C, Couraud PO, Dehouck MP, Cecchelli R, Karamanos Y, Flahaut C. Proteomics; 13(7):1185-1199


Article dans une revue17 documents

  • D. Mokart, C. Saillard, C. Zemmour, M. Bisbal, A. Sannini, et al.. Early prognostic factors in septic shock cancer patients: a prospective study with a proteomic approach. Acta Anaesthesiologica Scandinavica, Wiley, 2018, 62 (4), pp.493-503. 〈10.1111/aas.13060〉. 〈hal-01780657〉
  • Albertus Viljoen, Matthias Richard, Phuong Chi Nguyen, Patrick Fourquet, Luc Camoin, et al.. Cyclipostins and cyclophostin analogs inhibit the antigen 85C from Mycobacterium tuberculosis both in vitro and in vivo. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2018, 293 (8), pp.2755-2769. 〈10.1074/jbc.RA117.000760〉. 〈hal-01770061〉
  • Julien Peltier, Jean-Pierre Roperch, Stéphane Audebert, Jean-Paul Borg, Luc Camoin. Activation peptide of the coagulation factor XIII (AP-F13A1) as a new biomarker for the screening of colorectal cancer. Clinical Proteomics, BioMed Central, 2018, 15 (1), 〈10.1186/s12014-018-9191-3〉. 〈hal-01783956〉
  • Ali Badache, Habib Bouguenina, Danièle Salaün, Aurélie Mangon, Leslie Muller, et al.. EB1-binding–myomegalin protein complex promotes centrosomal microtubules functions. Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 2017, 114 (50), pp.E10687 - E10696. 〈10.1073/pnas.1705682114〉. 〈hal-01765369〉
  • Sandeep Gopal, Laurence Veracini, Dominique Grall, Catherine Butori, Sébastien Schaub, et al.. Fibronectin-guided migration of carcinoma collectives. Nature Communications, Nature Publishing Group, 2017, 8, pp.14105. 〈10.1038/ncomms14105〉. 〈hal-01783964〉
  • Mathilde Guérin, Anthony Gonçalves, Yves Toiron, Emilie Baudelet, Stéphane Audebert, et al.. How may targeted proteomics complement genomic data in breast cancer?. Expert Review of Proteomics, Taylor & Francis, 2017, 14 (1), pp.43-54. 〈10.1080/14789450.2017.1256776〉. 〈hal-01489501〉
  • Thomas Bonacci, Stéphane Audebert, Luc Camoin, Emilie Baudelet, Juan-Lucio Iovanna, et al.. Regulation of NUB1 Activity through Non- Proteolytic Mdm2-Mediated Ubiquitination. PLoS ONE, Public Library of Science, 2017. 〈hal-01787875〉
  • Romain Roncagalli, Margot Cucchetti, Nicolas Jarmuzynski, Claude Grégoire, Elise Bergot, et al.. The scaffolding function of the RLTPR protein explains its essential role for CD28 co-stimulation in mouse and human T cells. Journal of Experimental Medicine, Rockefeller University Press, 2016, 213 (11), pp.2437-2457. 〈10.1084/jem.20160579〉. 〈hal-01455791〉
  • Loic Lebellec, François Bertucci, Emmanuelle Tresch-Bruneel, Emmanuelle Bompas, Yves Toiron, et al.. Circulating vascular endothelial growth factor (VEGF) as predictive factor of progression-free survival in patients with advanced chordoma receiving sorafenib: an analysis from a phase II trial of the french sarcoma group (GSF/GETO). Oncotarget, Impact journals, 2016, 7 (45), pp.73984-73994. 〈10.18632/oncotarget.12172〉. 〈hal-01453300〉
  • Peltier Julien, Jean P. Roperch, Stephane Audebert, Jean-Paul Borg, Luc Camoin. Quantitative proteomic analysis exploring progression of colorectal cancer: Modulation of the serpin family. Journal of Proteomics, Elsevier, 2016, 〈10.1016/j.jprot.2016.07.031〉. 〈inserm-01369621〉
  • Christophe Fraisier, Raquel Rodrigues, Vinh Vu Hai, Maya Belghazi, Stéphanie Bourdon, et al.. Hepatocyte pathway alterations in response to in vitro Crimean Congo hemorrhagic fever virus infection.. Virus Res, 2014, 179, pp.187-203. 〈10.1016/j.virusres.2013.10.013〉. 〈hal-00972351〉
  • Edwige Belotti, Tania M. Puvirajesinghe, Stéphane Audebert, Emilie Baudelet, Luc Camoin, et al.. Molecular Characterisation of Endogenous Vangl2/Vangl1 Heteromeric Protein Complexes. PLoS ONE, Public Library of Science, 2012, 7 (9), pp.e46213. 〈10.1371/journal.pone.0046213〉. 〈hal-01447666〉
  • Guillaume Bussone, Hanadi Dib, Mathieu Tamby, Cedric Broussard, Christian Federici, et al.. Identification of new autoantibody specificities directed at proteins involved in the transforming growth factor beta pathway in patients with systemic sclerosis.. Arthritis Research and Therapy, BioMed Central, 2011, 13 (3), pp.R74. 〈10.1186/ar3336〉. 〈inserm-00606111〉
  • J. Chamot-Rooke, G. Mikaty, C. Malosse, M. Soyer, A. Dumont, et al.. Posttranslational modification of pili upon cell contact triggers N. meningitidis dissemination.. Science, American Association for the Advancement of Science, 2011, 331 (6018), pp.778-782. 〈10.1126/science.1200729〉. 〈hal-00904588〉
  • Andréa Toma, Taghrid Laïka, Samy Haddouk, Sandrine Luce, Jean-Paul Briand, et al.. Recognition of human proinsulin leader sequence by class I-restricted T-cells in HLA-A*0201 transgenic mice and in human type 1 diabetes.. Diabetes, American Diabetes Association, 2009, 58 (2), pp.394-402. 〈10.2337/db08-0599〉. 〈hal-00357419〉
  • T. Boukpessi, S. Menashi, L. Camoin, J. M. Tencate, M. Goldberg, et al.. The effect of stromelysin-1 (MMP-3) on non-collagenous extracellular matrix proteins of demineralized dentin and the adhesive properties of restorative resins.. Biomaterials, Elsevier, 2008, epub ahead of print. 〈10.1016/j.biomaterials.2008.07.035〉. 〈hal-00319853〉
  • Julia Chamot-Rooke, B. Rousseau, F. Lanternier, G. Mikaty, E. Mairey, et al.. Alternative Neisseria spp. type IV pilin glycosylation with a glyceramido acetamido trideoxyhexose residue.. Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 2007, 104 (37), pp.14783-14788. 〈10.1073/pnas.0705335104〉. 〈hal-00904602〉