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HBV cure: why, how, when?

M. Levrero , B. Testoni , F. Zoulim
Current Opinion in Virology, 2016, 18, pp.135-143. ⟨10.1016/j.coviro.2016.06.003⟩
Article dans une revue hal-01797257v1
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Genome-wide identification of direct HBx genomic targets

Francesca Guerrieri , Laura Belloni , Daniel D’andrea , Natalia Pediconi , Loredana Le Pera , et al.
BMC Genomics, 2016, 18 (1), pp.184. ⟨10.1186/s12864-017-3561-5⟩
Article dans une revue inserm-01470815v1
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Targeting a phospho-STAT3-miRNAs pathway improves vesicular hepatic steatosis in an in vitro and in vivo model

Laura Belloni , Silvia Di Cocco , Francesca Guerrieri , Abigail D G Nunn , Silvia Piconese , et al.
Scientific Reports, 2018, 8, pp.13638. ⟨10.1038/s41598-018-31835-2⟩
Article dans une revue hal-04163408v1

New p63 targets in keratinocytes identified by a genome-wide approach.

Vigano M. A. , J. Lamartine , B. Testoni , D. Merico , D. Alotto , et al.
EMBO Journal, 2006, 25(21), pp.5105-16
Article dans une revue hal-00163351v1

Landscape of oncoviral genotype and co-infection via human papilloma and hepatitis B viral tumor in situ profiling

Adrian Bubie , Fabien Zoulim , Barbara Testoni , Brett Miles , Marshall Posner , et al.
iScience, 2021, 24 (4), pp.102368. ⟨10.1016/j.isci.2021.102368⟩
Article dans une revue hal-04012199v1
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Epigenetic heterogeneity after de novo assembly of native full-length Hepatitis B Virus genomes

Chloe Goldsmith , Damien Cohen , Anaëlle Dubois , Maria-Guadalupe Martinez , Kilian Petitjean , et al.
2021
Pré-publication, Document de travail hal-03400517v1

Can we cure hepatitis B virus with novel direct‐acting antivirals?

Maria Martinez , François Villeret , Barbara Testoni , Fabien Zoulim
Liver International, 2020, 40 (S1), pp.27-34. ⟨10.1111/liv.14364⟩
Article dans une revue hal-03932602v1

CRISPR-Cas9 Targeting of Hepatitis B Virus Covalently Closed Circular DNA Generates Transcriptionally Active Episomal Variants

Maria Guadalupe Martinez , Emmanuel Combe , Aurore Inchauspe , Philippe Emmanuel Mangeot , Elodie Delberghe , et al.
mBio, 2022, 13 (2), ⟨10.1128/mbio.02888-21⟩
Article dans une revue hal-04013092v1

Development of hepatocellular carcinoma in chronic hepatitis B patients with advanced fibrosis is independent of viral genotype

R. Kumar , B. Testoni , J. Fresquet , T.K. Lim , Y. Hao , et al.
Journal of Medical Virology, 2017, 89 (5), pp.845-848. ⟨10.1002/jmv.24707⟩
Article dans une revue hal-01797246v1

A roadmap for serum biomarkers for hepatitis B virus: current status and future outlook

Anna Kramvis , Kyong-Mi Chang , Maura Dandri , Patrizia Farci , Dieter Glebe , et al.
Nature reviews. Gastroenterology & hepatology, 2022, 19 (11), pp.727-745. ⟨10.1038/s41575-022-00649-z⟩
Article dans une revue hal-04013304v1

Performance of the cobas® HBV RNA automated investigational assay for the detection and quantification of circulating HBV RNA in chronic HBV patients

Caroline Scholtès , Aaron Hamilton , Marie‐laure Plissonnier , Caroline Charre , Beth Scott , et al.
Journal of Clinical Virology, 2022, 150-151, pp.105150. ⟨10.1016/j.jcv.2022.105150⟩
Article dans une revue hal-04013121v1
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Quantification of the Hepatitis B Virus cccDNA: Evidence-based guidelines for 2 monitoring the key obstacle of HBV cure 3 Short Title: cccDNA quantification harmonization 4 5

Lena Allweiss , Barbara Testoni , Mei Yu , Julie Lucifora , Chunkyu Ko , et al.
Gut, 2023, pp.gutjnl-2022-328380. ⟨10.1136/gutjnl-2022-328380⟩
Article dans une revue hal-03992742v1

Viral and immune factors associated with successful treatment withdrawal in HBeAg-negative chronic hepatitis B patients

Mireia García-López , Sabela Lens , Laura Pallett , Barbara Testoni , Sergio Rodríguez-Tajes , et al.
Journal of Hepatology, 2021, 74 (5), pp.1064-1074. ⟨10.1016/j.jhep.2020.11.043⟩
Article dans une revue hal-04012145v1
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Full-length 5'RACE identifies all major HBV transcripts in HBV-infected hepatocytes and patient serum

Bernd Stadelmayer , Audrey Diederichs , Fleur Chapus , Michel Rivoire , Gregory Neveu , et al.
Journal of Hepatology, 2020, 73, pp.40 - 51. ⟨10.1016/j.jhep.2020.01.028⟩
Article dans une revue hal-03490308v1

Eliminating cccDNA to cure hepatitis B virus infection

Fabien Zoulim , Barbara Testoni
Journal of Hepatology, 2023, 78 (4), pp.677-680. ⟨10.1016/j.jhep.2023.01.017⟩
Article dans une revue hal-04165765v1

Corrigendum to “Toll-like receptor 3 downregulation is an escape mechanism from apoptosis during hepatocarcinogenesis” [J Hepatol 71 (2019) 763–772]

Marc Bonnin , Nadim Fares , Barbara Testoni , Yann Estornes , Kathrin Weber , et al.
Journal of Hepatology, 2020, 72 (3), pp.594. ⟨10.1016/j.jhep.2019.11.001⟩
Article dans une revue hal-02888503v1

The TFIID subunit TAF4 regulates keratinocyte proliferation and has cell-autonomous and non-cell-autonomous tumour suppressor activity in mouse epidermis.

Anas Fadloun , Dominique Kobi , Jean-Christophe Pointud , Arup Kumar Indra , Marius Teletin , et al.
Development (Cambridge, England), 2007, 134 (16), pp.2947-58. ⟨10.1242/dev.005041⟩
Article dans une revue hal-00189186v1

Le dysfonctionnement mitochondrial, nouvelle cible thérapeutique pour restaurer les réponses immunitaires épuisées contre le VHB

Léa Clément , Barbara Testoni
Médecine/Sciences, 2022, 38 (2), pp.223-226. ⟨10.1051/medsci/2022011⟩
Article dans une revue hal-04116950v1
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Serum hepatitis B core-related antigen (HBcrAg) correlates with covalently closed circular DNA transcriptional activity in chronic hepatitis B patients

Barbara Testoni , Fanny Lebossé , Caroline Scholtes , Françoise Berby , Clothilde Miaglia , et al.
Journal of Hepatology, 2019, 70, pp.615 - 625. ⟨10.1016/j.jhep.2018.11.030⟩
Article dans une revue hal-03486936v1

Late hepatitis B reactivation following direct‐acting antiviral–based treatment of recurrent hepatitis C in an anti‐HBc–positive liver transplant recipient

Julien Vionnet , Manuel Pascual , Barbara Testoni , Christophe Combet , Sébastien Godat , et al.
Hepatology, 2018, 67 (2), pp.791-793. ⟨10.1002/hep.29528⟩
Article dans une revue hal-04165532v1

Global strategies are required to cure and eliminate HBV infection

Peter Revill , Barbara Testoni , Stephen Locarnini , Fabien Zoulim
Nature reviews. Gastroenterology & hepatology, 2016, 13 (4), pp.239-248. ⟨10.1038/nrgastro.2016.7⟩
Article dans une revue hal-01800031v1
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Inflammatory Gene Expression Associates with Hepatitis B Virus cccDNA- but Not Integrant-Derived Transcripts in HBeAg Negative Disease

Andrea Magri , James Harris , Valentina D’arienzo , Rosalba Minisini , Frank Jühling , et al.
Viruses, 2022, 14 (5), pp.1070. ⟨10.3390/v14051070⟩
Article dans une revue hal-04013137v1

New p63 targets in keratinocytes identified by a genome-wide approach.

M Alessandra Viganò , Jérôme Lamartine , Barbara Testoni , Daniele Merico , Daniela Alotto , et al.
EMBO Journal, 2006, 25 (21), pp.5105-16. ⟨10.1038/sj.emboj.7601375⟩
Article dans une revue hal-00425192v1
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Detection of the hepatitis B virus (HBV) covalently-closed-circular DNA (cccDNA) in mice transduced with a recombinant AAV-HBV vector

Julie Lucifora , Anna Salvetti , Xavier Marniquet , Laurent Mailly , Barbara Testoni , et al.
Antiviral Research, 2017, 145, pp.14-19. ⟨10.1016/j.antiviral.2017.07.006⟩
Article dans une revue hal-01953660v1
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G-quadruplexes control hepatitis B virus replication by promoting cccDNA transcription and phase separation in hepatocytes

Guillaume Giraud , Mélanie Rodà , Pélagie Huchon , Maud Michelet , Sarah Maadadi , et al.
Nucleic Acids Research, 2023, 52, pp.2290 - 2305. ⟨10.1093/nar/gkad1200⟩
Article dans une revue hal-04526638v1

Challenges to a Cure for HBV Infection

Barbara Testoni , Massimo Levrero , Fabien Zoulim
Seminars in Liver Disease, 2017, 37 (03), pp.231-242. ⟨10.1055/s-0037-1606212⟩
Article dans une revue hal-04165472v1
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Quantification and epigenetic evaluation of the residual pool of hepatitis B covalently closed circular DNA in long-term nucleoside analogue-treated patients

Fanny Lebossé , Aurore Inchauspé , Maëlle Locatelli , Clothilde Miaglia , Audrey Diederichs , et al.
Scientific Reports, 2020, 10 (1), pp.21097. ⟨10.1038/s41598-020-78001-1⟩
Article dans une revue hal-04012134v1

Gene Editing Technologies to Target HBV cccDNA

Maria Guadalupe Martinez , Elena Smekalova , Emmanuel Combe , Francine Gregoire , Fabien Zoulim , et al.
Viruses, 2022, 14 (12), pp.2654. ⟨10.3390/v14122654⟩
Article dans une revue hal-04013365v1

Ribavirin restores IFNα responsiveness in HCV-infected livers by epigenetic remodelling at interferon stimulated genes

Barbara Testoni , David Durantel , Fanny Lebossé , Judith Fresquet , François Helle , et al.
Gut, 2016, 65 (4), pp.672-682. ⟨10.1136/gutjnl-2014-309011⟩
Article dans une revue hal-01796188v1
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Cas9-targeted nanopore sequencing reveals epigenetic heterogeneity after de novo assembly of native full-length hepatitis B virus genomes

Chloe Goldsmith , Damien Cohen , Anaëlle Dubois , Maria Guadalupe Martinez , Kilian Petitjean , et al.
Microbial Genomics, 2021, 7 (5), pp.000507. ⟨10.1099/mgen.0.000507⟩
Article dans une revue hal-03247577v1