Bruno Senger

Documents

Publications

	RNA-dependent synthesis of ergosteryl-3β-O-glycine in Ascomycota expands the diversity of steryl-amino acids Nathaniel Yakobov , Nassira Mahmoudi , Guillaume Grob , Daisuke Yokokawa , Yusuke Saga Journal of Biological Chemistry, 2022, 298 (3), pp.101657. ⟨10.1016/j.jbc.2022.101657⟩ Article dans une revue hal-03796231v1
	Loss of seryl-tRNA synthetase ( SARS1 ) causes complex spastic paraplegia and cellular senescence Edgard Verdura , Bruno Senger , Miquel Raspall-Chaure , Agatha Schlüter , Nathalie Launay Journal of Medical Genetics, 2022, pp.jmedgenet-2022-108529. ⟨10.1136/jmg-2022-108529⟩ Article dans une revue hal-03798206v1
	Cex1 is a component of the COPI intracellular trafficking machinery Ludovic Enkler , Bruno Rinaldi , Johan Owen de Craene , Philippe Hammann , Osamu Nureki Biology Open, 2021, 10 (3), pp.bio058528. ⟨10.1242/bio.058528⟩ Article dans une revue hal-03288818v1
	Assigning mitochondrial localization of dual localized proteins using a yeast Bi-Genomic Mitochondrial-Split-GFP Gaétan Bader , Ludovic Enkler , Yuhei Araiso , Marine Hemmerle , Krystyna Binko eLife, 2020, 9, ⟨10.7554/eLife.56649⟩ Article dans une revue hal-02898815v1
	De Novo and Bi-allelic Pathogenic Variants in NARS1 Cause Neurodevelopmental Delay Due to Toxic Gain-of-Function and Partial Loss-of-Function Effects Andreea Manole , Stephanie Efthymiou , Emer O'Connor , Marisa I Mendes , Matthew Jennings American Journal of Human Genetics, 2020, 107 (2), pp.311-324. ⟨10.1016/j.ajhg.2020.06.016⟩ Article dans une revue hal-02992472v1
	RNA-dependent sterol aspartylation in fungi Nathaniel Yakobov , Frédéric Fischer , Nassira Mahmoudi , Yusuke Saga , Christopher D Grube Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (26), pp.14948-14957. ⟨10.1073/pnas.2003266117⟩ Article dans une revue pasteur-02869570v1
	Cytosolic aminoacyl-tRNA synthetases: Unanticipated relocations for unexpected functions Nathaniel Yakobov , Sylvain Debard , Frédéric Fischer , Bruno Senger , Hubert Dominique Becker Biochimica et Biophysica Acta - Gene Regulatory Mechanisms , 2018, 1861 (4), pp.387-400. ⟨10.1016/j.bbagrm.2017.11.004⟩ Article dans une revue hal-02370188v1
	Cex1 is a new component of the COPIb trans-Golgi-to-vacuole intracellular trafficking machinery Ludovic Enkler , O.J. de Craene , Bruno Rinaldi , Philippe Hammann , Osamu Nureki BioRxiv, 2018 Article dans une revue hal-02918644v1
	Nonconventional localizations of cytosolic aminoacyl-tRNA synthetases in yeast and human cells Sylvain Debard , Gaétan Bader , Johan-Owen de Craene , Ludovic Enkler , Séverine Bär Methods, 2017, 113, pp.91 - 104. ⟨10.1016/j.ymeth.2016.09.017⟩ Article dans une revue hal-01771885v1
	Expression of Nuclear and Mitochondrial Genes Encoding ATP Synthase Is Synchronized by Disassembly of a Multisynthetase Complex Mathieu Frechin , Ludovic Enkler , Emmanuel Tetaud , Daphné Laporte , Bruno Senger Molecular Cell, 2014, 56 (6), pp.763-776. ⟨10.1016/j.molcel.2014.10.015⟩ Article dans une revue hal-02370180v1
	Exploring the evolutionary diversity and assembly modes of multi-aminoacyl-tRNA synthetase complexes: Lessons from unicellular organisms Daphné Laporte , Jonathan Huot , Gaétan Bader , Ludovic Enkler , Bruno Senger FEBS Letters, 2014, 588 (23), pp.4268-4278. ⟨10.1016/j.febslet.2014.10.007⟩ Article dans une revue hal-02370182v1
	Crystal structure of Saccharomyces cerevisiae mitochondrial GatFAB reveals a novel subunit assembly in tRNA-dependent amidotransferases Yuhei Araiso , Jonathan Huot , Takuya Sekiguchi , Mathieu Frechin , Frédéric Fischer Nucleic Acids Research, 2014, 42 (9), pp.6052-6063. ⟨10.1093/nar/gku234⟩ Article dans une revue hal-02370178v1
	Crystal structure of Cex1p reveals the mechanism of tRNA trafficking between nucleus and cytoplasm Kayo Nozawa , Ryuichiro Ishitani , Tohru Yoshihisa , Mamoru Sato , Fumio Arisaka Nucleic Acids Research, 2013, 41 (6), pp.3901-3914. ⟨10.1093/nar/gkt010⟩ Article dans une revue hal-02370174v1
	Arc1p: anchoring, routing, coordinating. Mathieu Frechin , Daniel Kern , Robert Pierre Martin , Hubert Dominique Becker , Bruno Senger FEBS Letters, 2010, 584 (2), pp.427-33. ⟨10.1016/j.febslet.2009.11.037⟩ Article dans une revue hal-00451322v1
	Arc1p: Anchoring, routing, coordinating Mathieu Frechin , Daniel Kern , Robert Pierre Martin , Hubert Dominique Becker , Bruno Senger FEBS Letters, 2010, 584 (2), pp.427-433. ⟨10.1016/j.febslet.2009.11.037⟩ Article dans une revue hal-02370169v1
	Yeast mitochondrial Gln-tRNA(Gln) is generated by a GatFAB-mediated transamidation pathway involving Arc1p-controlled subcellular sorting of cytosolic GluRS. Mathieu Frechin , Bruno Senger , Mélanie Brayé , Daniel Kern , Robert Pierre Martin Genes and Development, 2009, 23 (9), pp.1119-30. ⟨10.1101/gad.518109⟩ Article dans une revue hal-00484960v1
	Yeast mitochondrial Gln-tRNAGln is generated by a GatFAB-mediated transamidation pathway involving Arc1p-controlled subcellular sorting of cytosolic GluRS M. Frechin , B. Senger , M. Braye , D. Kern , R. Martin Genes and Development, 2009, 23 (9), pp.1119-1130. ⟨10.1101/gad.518109⟩ Article dans une revue hal-02370167v1
	Deletion of EFL1 Results in Heterogeneity of the 60S GTPase-associated rRNA Conformation Jean-Sébastien Graindorge , Jean-Claude Rousselle , Bruno Senger , Pascal Lenormand , Abdelkader Namane Journal of Molecular Biology, 2005, 352 (2), pp.355-369. ⟨10.1016/j.jmb.2005.07.037⟩ Article dans une revue hal-02370162v1
	Role of Arc1p in the Modulation of Yeast Glutamyl-tRNA Synthetase Activity † Jean-Sébastien Graindorge , Bruno Senger , Denis Tritch , George Simos , Franco Fasiolo Biochemistry, 2005, 44 (4), pp.1344-1352. ⟨10.1021/bi049024z⟩ Article dans une revue hal-02370163v1
	Functional analysis in yeast of the Brix protein superfamily involved in the biogenesis of ribosomes Edith Bogengruber , Peter Briza , Edith Doppler , Herbert Wimmer , Lore Koller FEMS Yeast Research, 2003, 3 (1), pp.35-43. ⟨10.1111/j.1567-1364.2003.tb00136.x⟩ Article dans une revue hal-02370150v1
	Ribosome assembly in eukaryotes Micheline Fromont-Racine , Bruno Senger , Cosmin Saveanu , Franco Fasiolo Gene, 2003, 313, pp.17 - 42. ⟨10.1016/S0378-1119(03)00629-2⟩ Article dans une revue pasteur-01404699v1
	The Nucle(ol)ar Tif6p and Efl1p Are Required for a Late Cytoplasmic Step of Ribosome Synthesis Bruno Senger , Denis L.J. Lafontaine , Jean-Sebastien Graindorge , Olivier Gadal , Alain Camasses Molecular Cell, 2001, 8 (6), pp.1363-1373. ⟨10.1016/s1097-2765(01)00403-8⟩ Article dans une revue hal-02370147v1
	Yeast cytoplasmic and mitochondrial methionyl-tRNA synthetases: two structural frameworks for identical functions Bruno Senger , Laurence Despons , Philippe Walter , Hieronim Jakubowski , Franco Fasiolo Journal of Molecular Biology, 2001, 311 (1), pp.205-216. ⟨10.1006/jmbi.2001.4844⟩ Article dans une revue hal-02370141v1
	Mtr10p functions as a nuclear import receptor for the mRNA-binding protein Npl3p B. Senger EMBO Journal, 1998, 17 (8), pp.2196-2207. ⟨10.1093/emboj/17.8.2196⟩ Article dans une revue hal-02370138v1
	The Modified Wobble Base Inosine in Yeast tRNA Ile Is a Positive Determinant for Aminoacylation by Isoleucyl-tRNA Synthetase † Bruno Senger , Sylvie Auxilien , Uwe Englisch , Friedrich Cramer , Franco Fasiolo Biochemistry, 1997, 36 (27), pp.8269-8275. ⟨10.1021/bi970206l⟩ Article dans une revue hal-02370118v1
	Conservation in Evolution for a Small Monomeric Phenylalanyl-tRNA Synthetase of the tRNA Phe Recognition Nucleotides and Initial Aminoacylation Site † Ruslan Aphasizhev , Bruno Senger , Jens-Uwe Rengers , Mathias Sprinzl , Philippe Walter Biochemistry, 1996, 35 (1), pp.117-123. ⟨10.1021/bi9517998⟩ Article dans une revue hal-02369829v1
	The Presence of a D-Stem but not a T-Stem is Essential for Triggering Aminoacylation upon Anticodon Binding in Yeast Methionine tRNA Bruno Senger , Ruslan Aphasizhev , Philippe Walter , Franco Fasiolo Journal of Molecular Biology, 1995, 249 (1), pp.45-58. ⟨10.1006/jmbi.1995.0279⟩ Article dans une revue hal-02370102v1
	Modulation of the Suppression Efficiency and Amino Acid Identity of an Artificial Yeast Amber Isoleucine Transfer RNA in Escherichia coli by a G-U Pair in the Anticodon Stem V. Buttcher , B. Senger , S. Schumacher , J. Reinbolt , F. Fasiolo Biochemical and Biophysical Research Communications, 1994, 200 (1), pp.370-377. ⟨10.1006/bbrc.1994.1458⟩ Article dans une revue hal-02369873v1
	The anticodon triplet is not sufficient to confer methionine acceptance to a transfer RNA. B. Senger , L. Despons , P. Walter , F. Fasiolo Proceedings of the National Academy of Sciences of the United States of America, 1992, 89 (22), pp.10768-10771. ⟨10.1073/pnas.89.22.10768⟩ Article dans une revue hal-02369845v1
	Binding of the yeast tRNAMet anticodon by the cognate methionyl-tRNA synthetase involves at least two independent peptide regions Laurence Despons , Bruno Senger , Franco Fasiolo , Philippe Walter Journal of Molecular Biology, 1992, 225 (3), pp.897-907. ⟨10.1016/0022-2836(92)90409-d⟩ Article dans une revue hal-02369843v1
	Identification of potential amino acid residues supporting anticodon recognition in yeast methionyl-tRNA synthetase Laurence Despons , Philippe Walter , Bruno Senger , Jean-Pierre Ebel , Franco Fasiolo FEBS Letters, 1991, 289 (2), pp.217-220. ⟨10.1016/0014-5793(91)81073-h⟩ Article dans une revue hal-02369841v1

	Visualizing Mitochondrial Importability of a Protein Using the Yeast Bi-Genomic Mitochondrial-Split-GFP Strain and an Ordinary Fluorescence Microscope Marine Hemmerle , Bruno Senger , Roza Kucharczyk , Hubert Becker Mitochondria, 2497, Springer US, pp.255-267, 2022, Methods in Molecular Biology, ⟨10.1007/978-1-0716-2309-1_16⟩ Chapitre d'ouvrage hal-03798229v1
	Non-canonical inputs and outputs of tRNA aminoacylation Marine Hemmerle , Marion Wendenbaum , Guillaume Grob , Nathaniel Yakobov , Nassira Mahmoudi-Kaidi The Enzymes, 48, , 2020, Biology of Aminoacyl-tRNA Synthetases, ⟨10.1016/bs.enz.2020.04.003⟩ Chapitre d'ouvrage hal-02919274v1

	Etude de nouveaux aspects liés à la machinerie traductionnelle : amidotransférases et aminoacyl-ARNt synthétases. Bruno Senger Sciences du Vivant [q-bio]. Université Louis Pasteur - Strasbourg I, 2006 HDR tel-00270801v1

Bruno Senger

Publications

RNA-dependent synthesis of ergosteryl-3β-O-glycine in Ascomycota expands the diversity of steryl-amino acids

Loss of seryl-tRNA synthetase ( SARS1 ) causes complex spastic paraplegia and cellular senescence

Cex1 is a component of the COPI intracellular trafficking machinery

Assigning mitochondrial localization of dual localized proteins using a yeast Bi-Genomic Mitochondrial-Split-GFP

De Novo and Bi-allelic Pathogenic Variants in NARS1 Cause Neurodevelopmental Delay Due to Toxic Gain-of-Function and Partial Loss-of-Function Effects

RNA-dependent sterol aspartylation in fungi

Cytosolic aminoacyl-tRNA synthetases: Unanticipated relocations for unexpected functions

Cex1 is a new component of the COPIb trans-Golgi-to-vacuole intracellular trafficking machinery

Nonconventional localizations of cytosolic aminoacyl-tRNA synthetases in yeast and human cells

Expression of Nuclear and Mitochondrial Genes Encoding ATP Synthase Is Synchronized by Disassembly of a Multisynthetase Complex

Exploring the evolutionary diversity and assembly modes of multi-aminoacyl-tRNA synthetase complexes: Lessons from unicellular organisms

Crystal structure of Saccharomyces cerevisiae mitochondrial GatFAB reveals a novel subunit assembly in tRNA-dependent amidotransferases

Crystal structure of Cex1p reveals the mechanism of tRNA trafficking between nucleus and cytoplasm

Arc1p: anchoring, routing, coordinating.

Arc1p: Anchoring, routing, coordinating

Yeast mitochondrial Gln-tRNA(Gln) is generated by a GatFAB-mediated transamidation pathway involving Arc1p-controlled subcellular sorting of cytosolic GluRS.

Yeast mitochondrial Gln-tRNAGln is generated by a GatFAB-mediated transamidation pathway involving Arc1p-controlled subcellular sorting of cytosolic GluRS

Deletion of EFL1 Results in Heterogeneity of the 60S GTPase-associated rRNA Conformation

Role of Arc1p in the Modulation of Yeast Glutamyl-tRNA Synthetase Activity †

Functional analysis in yeast of the Brix protein superfamily involved in the biogenesis of ribosomes

Ribosome assembly in eukaryotes

The Nucle(ol)ar Tif6p and Efl1p Are Required for a Late Cytoplasmic Step of Ribosome Synthesis

Yeast cytoplasmic and mitochondrial methionyl-tRNA synthetases: two structural frameworks for identical functions

Mtr10p functions as a nuclear import receptor for the mRNA-binding protein Npl3p

The Modified Wobble Base Inosine in Yeast tRNA Ile Is a Positive Determinant for Aminoacylation by Isoleucyl-tRNA Synthetase †

Conservation in Evolution for a Small Monomeric Phenylalanyl-tRNA Synthetase of the tRNA Phe Recognition Nucleotides and Initial Aminoacylation Site †

The Presence of a D-Stem but not a T-Stem is Essential for Triggering Aminoacylation upon Anticodon Binding in Yeast Methionine tRNA

Modulation of the Suppression Efficiency and Amino Acid Identity of an Artificial Yeast Amber Isoleucine Transfer RNA in Escherichia coli by a G-U Pair in the Anticodon Stem

The anticodon triplet is not sufficient to confer methionine acceptance to a transfer RNA.

Binding of the yeast tRNAMet anticodon by the cognate methionyl-tRNA synthetase involves at least two independent peptide regions

Identification of potential amino acid residues supporting anticodon recognition in yeast methionyl-tRNA synthetase

Visualizing Mitochondrial Importability of a Protein Using the Yeast Bi-Genomic Mitochondrial-Split-GFP Strain and an Ordinary Fluorescence Microscope

Non-canonical inputs and outputs of tRNA aminoacylation

Etude de nouveaux aspects liés à la machinerie traductionnelle : amidotransférases et aminoacyl-ARNt synthétases.