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WNT/β-catenin signalling is activated in aldosterone-producing adenomas and controls aldosterone production

Annabel Berthon , Coralie Drelon , Bruno Ragazzon , Sheerazed Boulkroun , Frédérique Tissier , et al.
Human Molecular Genetics, 2014, 23 (4), pp.889-905. ⟨10.1093/hmg/ddt484⟩
Article dans une revue hal-02108060v1
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Growth factor receptor binding protein 14 inhibition triggers insulin-induced mouse hepatocyte proliferation and is associated with hepatocellular carcinoma

Lucille Morzyglod , Michèle Caüzac , Lucie Popineau , Pierre-Damien Denechaud , Lluis Fajas , et al.
Hepatology, 2017, 65 (4), pp.1352-1368. ⟨10.1002/hep.28972/suppinfo⟩
Article dans une revue hal-01606970v1
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Novel Insights into the Genetics and Pathophysiology of Adrenocortical Tumors

Ludivine Drougat , Hanin Omeiri , Lucile Lefevre , Bruno Ragazzon
Frontiers in Endocrinology, 2015, 6, pp.96. ⟨10.3389/fendo.2015.00096⟩
Article dans une revue inserm-01169814v1
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Cullin 3 targets the tumor suppressor gene ARMC5 for ubiquitination and degradation

Isadora Pontes Cavalcante , Anna Vaczlavik , Ludivine Drougat , Claudimara Ferini , Karine Perlemoine , et al.
Endocrine-Related Cancer, 2020
Article dans une revue hal-03014005v1
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IGF2 promotes growth of adrenocortical carcinoma cells, but its overexpression does not modify phenotypic and molecular features of adrenocortical carcinoma.

Marine Guillaud-Bataille , Bruno Ragazzon , Aurélien de Reyniès , Claire Chevalier , Isabelle Francillard , et al.
PLoS ONE, 2014, 9 (8), pp.e103744. ⟨10.1371/journal.pone.0103744⟩
Article dans une revue inserm-01068039v1
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EZH2 cooperates with E2F1 to stimulate expression of genes involved in adrenocortical carcinoma aggressiveness

Houda Tabbal , Amandine Septier , Mickael Mathieu , Coralie Drelon , Stéphanie Rodriguez , et al.
British Journal of Cancer, 2019, 121 (5), pp.384-394. ⟨10.1038/s41416-019-0538-y⟩
Article dans une revue hal-03060155v1
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Aldo Keto Reductase 1B7 and Prostaglandin F2α Are Regulators of Adrenal Endocrine Functions

Sarah Lambert-Langlais , Jean-Christophe Pointud , Anne-Marie Lefrançois-Martinez , Fanny Volat , Michèle Manin , et al.
PLoS ONE, 2009, 4 (10), pp.e7309. ⟨10.1371/journal.pone.0007309⟩
Article dans une revue hal-02366477v1
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A kinome siRNA screen identifies HGS as a potential target for liver cancers with oncogenic mutations in CTNNB1

Frédéric Canal , Elodie Anthony , Aurianne Lescure , Elaine del Nery , Jacques Camonis , et al.
BMC Cancer, 2015, 15 (1), pp.1020. ⟨10.1186/s12885-015-2037-8⟩
Article dans une revue inserm-01254133v1

Cushing's Syndrome and Fetal Features Resurgence in Adrenal Cortex–Specific Prkar1a Knockout Mice

Isabelle Sahut-Barnola , Cyrille de Joussineau , Pierre Val , Sarah Lambert-Langlais , Christelle Damon , et al.
PLoS Genetics, 2010, 6 (6), ⟨10.1371/journal.pgen.1000980⟩
Article dans une revue hal-01922134v1
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novel insights into the genetics and pathophysiology of adrenocortical tumors

Ludivine Drougat , Hanin Omeiri , Lucile Lefèvre , Bruno Ragazzon
EPJdirectC - Articles, 2015, ⟨10.3389/fendo.2015.00096⟩
Article dans une revue inserm-01247515v1

EZH2 is overexpressed in adrenocortical carcinoma and is associated with disease progression

Coralie Drelon , Annabel Berthon , Mickael Mathieu , Bruno Ragazzon , Rork Kuick , et al.
Human Molecular Genetics, 2016, 25 (13), pp.ddw136. ⟨10.1093/hmg/ddw136⟩
Article dans une revue hal-02108050v1

ARMC5 Mutations in a Large Cohort of Primary Macronodular Adrenal Hyperplasia: Clinical and Functional Consequences

Stéphanie Espiard , Ludivine Drougat , Rossella Libé , Guillaume Assié , Karine Perlemoine , et al.
Journal of Clinical Endocrinology and Metabolism, 2015, 100 (6), pp.E926-E935. ⟨10.1210/jc.2014-4204⟩
Article dans une revue hal-01813998v1

Adrenocorticotropin/3′,5′-Cyclic AMP-Mediated Transcription of the Scavenger akr1-b7 Gene in Adrenocortical Cells Is Dependent on Three Functionally Distinct Steroidogenic Factor-1-Responsive Elements

Pierre Val , Christelle Aigueperse , Bruno Ragazzon , Georges Veyssière , Anne-Marie Lefrançois-Martinez , et al.
Endocrinology, 2004, 145 (2), pp.508-518. ⟨10.1210/en.2003-1093⟩
Article dans une revue hal-02366490v1

Lack of the presynaptic RhoGAP protein oligophrenin1 leads to cognitive disabilities through dysregulation of the cAMP/PKA signalling pathway

Malik Khelfaoui , Frédéric Gambino , Xander Houbaert , Bruno Ragazzon , Christian Muller , et al.
Philosophical Transactions of the Royal Society B: Biological Sciences, 2014, 369 (1633), pp.20130160. ⟨10.1098/rstb.2013.0160⟩
Article dans une revue hal-02392406v1
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Combined transcriptome studies identify AFF3 as a mediator of the oncogenic effects of β-catenin in adrenocortical carcinoma

Lucile Lefèvre , Hanin Omeiri , Ludivine Drougat , Constanze Hantel , Mathieu Giraud , et al.
Oncogenesis, 2015, 4 (7), pp.e161. ⟨10.1038/oncsis.2015.20⟩
Article dans une revue inserm-01182372v1

Genomic classification of benign adrenocortical lesions

Simon Faillot , Thomas Foulonneau , Mario Néou , Stéphanie Espiard , Simon Garinet , et al.
Endocrine-Related Cancer, 2020, ⟨10.1530/ERC-20-0128⟩
Article dans une revue hal-03049026v1
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Contrôle hormonal de la stéroïdogenèse et tumorigenèse cortico-surrénalienne : utilisation de la trangenèse chez la souris pour le développement de nouvelles lignées cellulaires et de modèles animaux de pathologies tumorales par oncogenèse ciblée

Bruno Ragazzon
Biologie du développement. Université Blaise Pascal - Clermont-Ferrand II, 2005. Français. ⟨NNT : 2005CLF21629⟩
Thèse tel-00686939v1
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AXIN deficiency in human and mouse hepatocytes induces hepatocellular carcinoma in the absence of β-catenin activation

Shirley Abitbol , Rajae Dahmani , Cédric Coulouarn , Bruno Ragazzon , Bernhard Mlecnik , et al.
Journal of Hepatology, 2018, 68 (6), pp.1203-1213. ⟨10.1016/j.jhep.2017.12.018⟩
Article dans une revue hal-01807225v2

8Cl-cAMP modifies the balance between PKAR1 and PKAR2 and modulates the cell cycle, growth and apoptosis in human adrenocortical H295R cells

Zhor Bouizar , Bruno Ragazzon , Lucie Viou , Mariuccia Hortane , Jérôme Bertherat , et al.
Journal of Molecular Endocrinology, 2010, 44 (6), pp.331-347. ⟨10.1677/JME-09-0120⟩
Article dans une revue hal-02376050v1

ARMC5 Mutations in Macronodular Adrenal Hyperplasia with Cushing's Syndrome

Guillaume Assié , Rossella Libé , Stéphanie Espiard , Marthe Rizk-Rabin , Anne Guimier , et al.
New England Journal of Medicine, 2013, 369 (22), pp.2105-2114. ⟨10.1056/NEJMoa1304603⟩
Article dans une revue hal-02376105v1

Novel Grb14-Mediated Cross Talk between Insulin and p62/Nrf2 Pathways Regulates Liver Lipogenesis and Selective Insulin Resistance

Lucie Popineau , Lucille Morzyglod , Nadege Carre , Michele Cauzac , Pascale Bossard , et al.
Molecular and Cellular Biology, 2016, 36 (16), pp.2168 - 2181. ⟨10.1128/MCB.00170-16⟩
Article dans une revue hal-01602453v1
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Analysis of the Role of Igf2 in Adrenal Tumour Development in Transgenic Mouse Models

Coralie Drelon , Annabel Berthon , Bruno Ragazzon , Frédérique Tissier , Roberto Bandiera , et al.
PLoS ONE, 2012, 7 (8), pp.e44171. ⟨10.1371/journal.pone.0044171⟩
Article dans une revue hal-01922100v1

A transgenic mouse line with specific Cre recombinase expression in the adrenal cortex

Sarah Lambert-Langlais , Pierre Val , Samuel Guyot , Bruno Ragazzon , Isabelle Sahut-Barnola , et al.
Molecular and Cellular Endocrinology, 2009, 300 (1-2), pp.197-204. ⟨10.1016/j.mce.2008.10.045⟩
Article dans une revue hal-02366480v1
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Link between steroidogenesis, the cell cycle, and PKA in adrenocortical tumor cells

Marthe Rizk-Rabin , Sabrina Chaoui-Ibadioune , Anna Vaczlavik , Christopher Ribes , Michel Polak , et al.
Molecular and Cellular Endocrinology, 2020, 500, ⟨10.1016/j.mce.2019.110636⟩
Article dans une revue hal-03014038v1

Cullin 3 targets the tumor suppressor gene ARMC5 for ubiquitination and degradation

Isadora Pontes Cavalcante , Anna Vaczlavik , Ludivine Drougat , Claudimara Ferini Pacicco Lotfi , Karine Perlemoine , et al.
Endocrine-Related Cancer, 2020, 27 (4), pp.221-230. ⟨10.1530/ERC-19-0502⟩
Article dans une revue hal-02990622v1

Adrenocorticotropin-Dependent Changes in SF-1/DAX-1 Ratio Influence Steroidogenic Genes Expression in a Novel Model of Glucocorticoid-Producing Adrenocortical Cell Lines Derived from Targeted Tumorigenesis

Bruno Ragazzon , Anne-Marie Lefrançois-Martinez , Pierre Val , Isabelle Sahut-Barnola , Colette Tournaire , et al.
Endocrinology, 2006, 147 (4), pp.1805-1818. ⟨10.1210/en.2005-1279⟩
Article dans une revue hal-02366485v1

PKA regulatory subunit 1A inactivating mutation induces serotonin signaling in primary pigmented nodular adrenal disease

Zakariae Bram , Estelle Louiset , Bruno Ragazzon , Sylvie Renouf , Julien Wils , et al.
JCI Insight, 2016, 1 (15), pp.e87958. ⟨10.1172/jci.insight.87958⟩
Article dans une revue hal-02108040v1

Integrated genomic characterization of adrenocortical carcinoma.

Guillaume Assié , Eric Letouzé , Martin Fassnacht , Anne Jouinot , Windy Luscap , et al.
Nature Genetics, 2014, 46 (6), pp.607-12. ⟨10.1038/ng.2953⟩
Article dans une revue hal-01255809v1
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Hormonal and spatial control of SUMOylation in the human and mouse adrenal cortex

Typhanie Dumontet , Isabelle Sahut‐barnola , Damien Dufour , Anne-Marie Lefrançois-Martinez , Annabel Berthon , et al.
FASEB Journal, 2019, 33 (9), pp.10218-10230. ⟨10.1096/fj.201900557R⟩
Article dans une revue hal-03060127v1

MET overexpression and activation favors invasiveness in a model of anaplastic thyroid cancer

Cyril Garcia , Camille Buffet , Laila El Khattabi , Marthe Rizk-Rabin , Karine Perlemoine , et al.
Oncotarget, 2019, 10 (23), ⟨10.18632/oncotarget.26798⟩
Article dans une revue hal-02325867v1