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Bruno Le Pioufle

Bruno LE PIOUFLE,  Professor at the Ecole Normale Supérieure Paris-Saclay

E.N.S. Paris-Saclay, 4 av. des sciences, 91190 Gif-sur-Yvette, France,

Phone: 001 33 1 81875560, email: bruno.le-pioufle@ens-paris-saclay.fr


 

 EDUCATION:

1997:                   Accreditation to supervise research , University of PARIS 11

1991:                   French Ph.D., University of  PARIS 11

 

PROFESSIONAL EXPERIENCE:

Since 2020:                 Director of Institut d'Alembert (CNRS FR 3242, University Paris-Saclay)

since 2007:                  Professor at ENS Cachan, (now ENS Paris-Saclay)
2005-2007:                  Director of LIMMS/CNRS IIS,UMI 2820, University of Tokyo, group of S. Takeuchi
1999:                           Professor à l’ENS de Cachan, Creation and Direction of BIOMIS group(1999-2005)
1997-1999:                  CNRS researcher at LIMMS, University of Tokyo, IIS, group of H. Fujita
1992-1997:                  Associate professor ar ENS  Cachan

 

MAIN RESEARCH ACTIVITIES

B. Le Pioufle have been working since 1997 on the conception of bio-medical purpose microsystems. His main scientific concerns are 1) the conception of microfluidic biochips for the monitoring of membrane proteins and ion channels and 2) cell biochips. He spent 4 years at University of Tokyo, in the groups of H. Fujita, then in the group of S. Takeuchi. He was Director of LIMMS (International laboratory between CNRS and University of Tokyo). He  worked in collaboration with S. Takeuchi on the conception of parallelized biochips for the screening on transmembrane molecules. He is also working on biochips for the cell analysis and treatment, and organ on chip. He is working on cell handling on a chip using dielectrophoresis, cell electroporation on a chip, microfluidics, surface functionalization of biochips. The main projects on which he has been working are 1) the study and conception of highly parallelized cell biochips for analysis (high throughput screening) or treatment (gene transfection on a chip)  2) the study and conception of biochips for ex-vivo (on a chip) analysis of physiological models 3) the design of biochips designed for the delivery of high amplitude  electrical nanosecond pulses for the treatment of cells.

 

 

Journal articles76 documents

  • Manon Boul, Nassima Benzoubir, Antonietta Messina, Rasta Ghasemi, Ismail Ben Mosbah, et al.. A versatile microfluidic tool for the 3D culture of HepaRG cells seeded at various stages of differentiation. Scientific Reports, Nature Publishing Group, 2021, 11, pp.14075. ⟨10.1038/s41598-021-92011-7⟩. ⟨hal-03286077⟩
  • Maria Alejandra Lizarralde-Iragorri, Sophie Lefevre, Sylvie Cochet, Sara El Hoss, Valentine Brousse, et al.. Oxidative stress activates red cell adhesion to laminin in sickle cell disease. Haematologica, Ferrata Storti Foundation, In press, pp.haematol.2020.261586. ⟨10.3324/haematol.2020.261586⟩. ⟨hal-02929195⟩
  • Tieying Xu, Maria Lizarralde-Iragorri, Jean Roman, Rasta Ghasemi, Jean-Pierre Lefevre, et al.. Characterization of red blood cell microcirculatory parameters using a bioimpedance microfluidic device. Scientific Reports, Nature Publishing Group, 2020, ⟨10.1038/s41598-020-66693-4⟩. ⟨hal-02872830⟩
  • Yu-Sheng Lin, Sung Tsang, Sakina Bensalem, Ching-Chu Tsai, Shiang-Jiuun Chen, et al.. Electrorotation of single microalgae cells during lipid accumulation for assessing cellular dielectric properties and total lipid contents. Biosensors and Bioelectronics, Elsevier, 2020, pp.112772. ⟨10.1016/j.bios.2020.112772⟩. ⟨hal-03006108⟩
  • Sakina Bensalem, Dominique Pareau, Bertrand Cinquin, Olivier Français, Bruno Le Pioufle, et al.. Impact of pulsed electric fields and mechanical compressions on the permeability and structure of Chlamydomonas reinhardtii cells. Scientific Reports, Nature Publishing Group, 2020, 10, pp.2668. ⟨10.1038/s41598-020-59404-6⟩. ⟨hal-02486263⟩
  • Pedro Moura, Maria Lizarralde Iragorri, Olivier Français, Bruno Le Pioufle, Johannes Dobbe, et al.. Reticulocyte and red blood cell deformation triggers specific phosphorylation events. Blood Advances, The American Society of Hematology, 2019, 3 (17), pp.2653-2663. ⟨10.1182/bloodadvances.2019000545⟩. ⟨hal-02289553⟩
  • Claudia Trainito, Daniel Sweeney, Jaka Čemažar, Eva Schmelz, Olivier Français, et al.. Characterization of sequentially-staged cancer cells using electrorotation. PLoS ONE, Public Library of Science, 2019, 14 (9), pp.e0222289. ⟨10.1371/journal.pone.0222289⟩. ⟨hal-02301212⟩
  • Clyde Midelet, Bruno Le Pioufle, Martinus Werts. Brownian Motion and Large Electric Polarizabilities Facilitate Dielectrophoretic Capture of Sub‐200 nm Gold Nanoparticles in Water. ChemPhysChem, Wiley-VCH Verlag, 2019, 20 (24), pp.3354-3365. ⟨10.1002/cphc.201900662⟩. ⟨hal-02334475⟩
  • Pierre Bodenes, Sakina Bensalem, Olivier Français, Dominique Pareau, Bruno Le Pioufle, et al.. Inducing reversible or irreversible pores in Chlamydomonas reinhardtii with electroporation: Impact of treatment parameters. Algal Research - Biomass, Biofuels and Bioproducts, Elsevier, 2019, 37, pp.124-132. ⟨10.1016/j.algal.2018.11.016⟩. ⟨hal-01944176⟩
  • Jean Roman, Bruno Le Pioufle, Loïc Auvray, Juan Pelta, Laurent Bacri. From current trace to the understanding of confined media. European Physical Journal E: Soft matter and biological physics, EDP Sciences: EPJ, 2018, 41, pp.99. ⟨10.1140/epje/i2018-11709-5⟩. ⟨hal-01882378⟩
  • Jean Roman, Olivier Français, Nathalie Jarroux, Gilles Patriarche, Juan Pelta, et al.. Solid-state nanopore easy chip integration in a cheap and reusable microfluidic device for ion transport and polymer conformation sensing. ACS Sensors, American Chemical Society, 2018, 3 (10), pp.2129-2137. ⟨10.1021/acssensors.8b00700⟩. ⟨hal-01891773⟩
  • Sakina Bensalem, Filipa Lopes, Pierre Bodénès, Dominique Pareau, Olivier Français, et al.. Understanding the mechanisms of lipid extraction from microalga Chlamydomonas reinhardtii after electrical field solicitations and mechanical stress within a microfluidic device. Bioresource Technology, Elsevier, 2018, 257, pp.129 - 136. ⟨10.1016/j.biortech.2018.01.139⟩. ⟨hal-01789219⟩
  • Sakina Bensalem, Filipa Lopes, Pierre Bodénès, Dominique Pareau, Olivier Français, et al.. Structural changes of Chlamydomonas reinhardtii cells during lipid enrichment and after solvent exposure. Data in Brief, Elsevier, 2018, 17, pp.1283 - 1287. ⟨10.1016/j.dib.2018.02.042⟩. ⟨hal-01789908⟩
  • Maria Alejandra Lizarralde Iragorri, Sara El Hoss,, Valentine Brousse, Sophie Lefevre, Michael Dussiot, et al.. A microfluidic approach to study the effect of mechanical stress on erythrocytes in sickle cell disease. Lab on a Chip, Royal Society of Chemistry, 2018, 18 (19), pp.2975-2984. ⟨10.1039/C8LC00637G⟩. ⟨hal-01875109⟩
  • Jean Roman, Nathalie Jarroux, Gilles Patriarche, Olivier Français, Juan Pelta, et al.. Functionalized Solid-State Nanopore Integrated in a Reusable Microfluidic Device for a Better Stability and Nanoparticle Detection. ACS Applied Materials & Interfaces, Washington, D.C. : American Chemical Society, 2017, 9 (48), pp.41634 - 41640. ⟨10.1021/acsami.7b14717⟩. ⟨hal-01661723⟩
  • Abdelhatif El Fellahi, Thierry Bore, Sakina Bensalem, Pierre Bodénès, Filipa Lopes, et al.. Monitoring of Microalgae Lipid Accumulation Using RF Open Ended Biosensor. IEEE Sensors Letters, IEEE, 2017, 1 (4), pp. 4500303. ⟨10.1109/LSENS.2017.2709082⟩. ⟨hal-01587262⟩
  • Jean Roman, Olivier Français, Nathalie Jarroux, Gilles Patriarche, Juan Pelta, et al.. Nanoparticle Electrical Analysis and Detection with a Solid-state Nanopore in a Microfluidic Device. Procedia Engineering, Elsevier, 2016, Proceedings of the 30th anniversary Eurosensors Conference – Eurosensors 2016, 4-7. Sepember 2016, Budapest, Hungary, 168, pp.1475-1478. ⟨10.1016/j.proeng.2016.11.425⟩. ⟨hal-02006469⟩
  • Barbara Sandor, Mickaël Marin, Claudine Lapouméroulie, Miklos Rabaï, Sophie Lefevre, et al.. Effects of Poloxamer 188 on red blood cell membrane properties in sickle cell anaemia. British Journal of Haematology, Wiley, 2016, 173 (1), pp.145 - 149. ⟨10.1111/bjh.13937⟩. ⟨hal-01881668⟩
  • Marie-Amelie de Menorval, Franck M. Andre, Aude Silve, Claire Dalmay, Olivier Français, et al.. Electric pulses: a flexible tool to manipulate cytosolic calcium concentrations and generate spontaneous-like calcium oscillations in mesenchymal stem cells. Scientific Reports, Nature Publishing Group, 2016, 6, ⟨10.1038/srep32331⟩. ⟨hal-01357904⟩
  • Pierre Bodénès, F. Lopes, D. Pareau, Olivier Français, B. Le Pioufle. Microdevice for studying the in situ permeabilization and characterization of Chlamydomonas reinhardtii in lipid accumulation phase. Algal Research - Biomass, Biofuels and Bioproducts, Elsevier, 2016, 16, pp.357-367. ⟨10.1016/j.algal.2016.03.023⟩. ⟨hal-01303998⟩
  • C. I. Trainito, E. Bayart, F. Subra, Olivier Français, B. Le Pioufle. The Electrorotation as a Tool to Monitor the Dielectric Properties of Spheroid During the Permeabilization. Journal of Membrane Biology, Springer Verlag (Germany), 2016, ⟨10.1007/s00232-016-9880-7⟩. ⟨hal-01284729⟩
  • Eric Perrin, Olivier Français, Bruno Le Pioufle, Bertrand David. Reproducing topography and roughness of osteoconductive biomaterials in a microfluidic device. Computer Methods in Biomechanics and Biomedical Engineering, Taylor & Francis, 2015, 18 (sup1), pp.2026-2027. ⟨10.1080/10255842.2015.1069567⟩. ⟨hal-01222451⟩
  • Julien Picot, Papa Alioune Ndour, Sophie D. Lefevre, Wassim El Nemer, Harvey Tawfik, et al.. A biomimetic microfluidic chip to study the circulation and mechanical retention of red blood cells in the spleen. American Journal of Hematology, Wiley, 2015, ⟨10.1002/ajh.23941⟩. ⟨hal-01113050⟩
  • Emilie Bisceglia, Myriam Cubizolles, Claudia Irene Trainito, Jean Berthier, Catherine Pudda, et al.. A generic and label free method based on dielectrophoresis for the continuous separation of microorganism from whole blood samples. Sensors and Actuators B: Chemical, Elsevier, 2015, 212, pp.335-343. ⟨10.1016/j.snb.2015.02.024⟩. ⟨hal-01121775⟩
  • C.I. Trainito, Olivier Français, B. Le Pioufle. Analysis of pulsed electric field effects on cellular tissue with Cole–Cole model: Monitoring permeabilization under inhomogeneous electrical field with bioimpedance parameter variations. Innovative Food Science and Emerging Technologies, Elsevier, 2015, 29, pp.193-200/10.1016/j.ifset.2015.02.004. ⟨10.1016/j.ifset.2015.02.004⟩. ⟨hal-01122453⟩
  • Claudia Irene Trainito, Olivier Français, Bruno Le Pioufle. Monitoring the permeabilization of a single cell in a microfluidic device, through the estimation of its dielectric properties based on combined dielectrophoresis and electrorotation in-situ experiments. Electrophoresis, Wiley-VCH Verlag, 2015, ⟨10.1002/elps.201400482⟩. ⟨hal-01116751⟩
  • Rémi Sieskind, Claudia Trainito, Olivier Français, Bruno Le Pioufle. Microsystème dédié à l’étude de la polarisation diélectrique de microparticules dans le cadre de formation master recherche : application au micropositionnement 3D de cellules par force de diélectrophorèse. Journal sur l'enseignement des sciences et technologies de l'information et des systèmes, EDP Sciences, 2015, 14, http://dx.doi.org/10.1051/j3ea/2015007. ⟨10.1051/j3ea/2015007⟩. ⟨hal-01122450⟩
  • Julien Duez, John P. Holleran, Papa Alioune Ndour, Sasdekumar Loganathan, Pascal Amireault, et al.. Splenic retention of Plasmodium falciparum gametocytes to block the transmission of malaria. Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2015, pp.AAC.05030-14. ⟨10.1128/AAC.05030-14⟩. ⟨hal-01158996⟩
  • Feriel Sihem Hamdi, M. Woytasik, Magdalèna Couty, Olivier Français, Bruno Le Pioufle, et al.. Low Temperature Irreversible Poly(DiMethyl) Siloxane Packaging of Silanized SU8 Microchannels: Characterization and Lab-on-Chip Application. Journal of Microelectromechanical Systems, Institute of Electrical and Electronics Engineers, 2014, pp.ISSN 1057-7157. ⟨10.1109/JMEMS.2014.2331454⟩. ⟨hal-01063867⟩
  • Martinus H. V. Werts, Florent Allix, Olivier Français, Céline Frochot, Laurent Griscom, et al.. Manipulation and optical detection of colloidal functional plasmonic nanostructures in microfluidic systems. IEEE Journal of Selected Topics in Quantum Electronics, Institute of Electrical and Electronics Engineers, 2014, 20, pp.6900613. ⟨10.1109/JSTQE.2013.2284549⟩. ⟨hal-00961328⟩
  • Feriel Sihem Hamdi, Olivier Français, Elisabeth Dufour-Gergam, Bruno Le Pioufle. How medium osmolarity influences dielectrophoretically assisted on-chip electrofusion. Bioelectrochemistry, Elsevier, 2014, pp.42-46. ⟨10.1016/j.bioelechem.2014.05.004⟩. ⟨hal-01026162⟩
  • Angélique Coutable, Vincent Noireaux, Bruno Lepioufle, Olivier Français, Christophe Vieu, et al.. Insertion of Functional Proteins into Bilayer Lipid Membrane using a Cell-Free Expression System. Biophysical Journal, Biophysical Society, 2013, 104 (2), pp.548A. ⟨10.1016/j.bpj.2012.11.3039⟩. ⟨hal-01767698⟩
  • Emilie Bisceglia, Myriam Cubizolles, Frederic Mallard, Francoise Vinet, Olivier Français, et al.. Micro-organism extraction from biological samples using DEP forces enhanced by osmotic shock. Lab on a Chip, Royal Society of Chemistry, 2013, 13 (5), pp.901-909. ⟨10.1039/c2lc41128h⟩. ⟨hal-00785335⟩
  • Olivier Français, Bruno Le Pioufle. La mesure de la bio-impédance d'un végétal comme moyen d'introduire le domaine de la biologie dans une formation E.E.A.. Journal sur l'enseignement des sciences et technologies de l'information et des systèmes, EDP Sciences, 2013, 12, 2013, pp.0018. ⟨10.1051/j3ea/2013018⟩. ⟨hal-00934120⟩
  • Feriel S Hamdi, Olivier Français, Frederic Subra, Elisabeth Dufour-Gergam, Bruno Le Pioufle. Microarray of non-connected gold pads used as high density electric traps for parallelized pairing and fusion of cells. Biomicrofluidics, 2013, 7, pp.044101. ⟨10.1063/1.4813062⟩. ⟨hal-00861239⟩
  • Feriel Sihem Hamdi, Olivier Français, Frédéric Subra, Wei Wang, Marion Woytasik, et al.. Study of the transmembrane potential distribution of cell pairs in a microfluidic device using polymer obstacles to initiate electrofusion. European Physical Journal: Applied Physics, EDP Sciences, 2013, 62 (01), pp.11202-11212. ⟨10.1051/epjap/2013120392⟩. ⟨hal-00812130⟩
  • M. Chabanon, H. Duval, O. Francais, Bruno Le Pioufle, E. Perrin, et al.. Discrete model combined with mimetic microfluidic chips to study cell growth in porous scaffold under flow conditions.. Computer Methods in Biomechanics and Biomedical Engineering, Taylor & Francis, 2012, 15 (1), pp.25-26. ⟨10.1080/10255842.2012.713699⟩. ⟨hal-00751801⟩
  • Wei Wang, Laura Monlezun, Martin Picard, Philippe Benas, Olivier Français, et al.. Activity Monitoring of Functional OprM Using a Biomimetic Microfluidic Device. Analyst, Royal Society of Chemistry, 2012, 137 (4), pp.847-852. ⟨10.1039/c2an16007b⟩. ⟨hal-00739216⟩
  • Claire Dalmay, M. A. de Menorval, O. Francais, L. M. Mir, Bruno Le Pioufle. A microfluidic device with removable packaging for the real time visualisation of intracellular effects of nanosecond electrical pulses on adherent cells. Lab on a Chip, Royal Society of Chemistry, 2012, 12 (22), pp.4709-15. ⟨10.1039/c2lc40857k⟩. ⟨hal-00745203⟩
  • Guillaume Mottet, Bruno Le Pioufle, Lluis M. Mir. High-resolution analyses of cell fusion dynamics in a biochip. Electrophoresis, Wiley-VCH Verlag, 2012, 33 (16), pp.2508-2515. ⟨10.1002/elps.201200112⟩. ⟨hal-00738706⟩
  • Claire Dalmay, Julien Villemejane, Vanessa Joubert, Aude Silve, Delia Arnaud-Cormos, et al.. A microfluidic biochip for the nanoporation of living cells. Biosensors and Bioelectronics, Elsevier, 2011, 26 (12), pp.4649-4655. ⟨10.1016/j.bios.2011.03.020⟩. ⟨hal-00674584⟩
  • Claire Dalmay, Julien Villemejane, Vanessa Joubert, Olivier Français, Lluis M. Mir, et al.. Design and realization of a microfluidic device devoted to the application of ultra-short pulses of electrical field to living cells. Sensors and Actuators B: Chemical, Elsevier, 2011, 160 (1), pp.1573-1580. ⟨10.1016/j.snb.2011.09.009⟩. ⟨hal-00738711⟩
  • Marie Breton, Gaelle Prevel, Jean-Frederic Audibert, Robert Pansu, Patrick Tauc, et al.. Solvatochromic dissociation of non-covalent fluorescent organic nanoparticles upon cell internalization. Physical Chemistry Chemical Physics, Royal Society of Chemistry, 2011, 13 (29), pp.13268-13276. ⟨10.1039/c1cp20877b⟩. ⟨hal-00739217⟩
  • Guillaume Mottet, Julien Villemejane, Luis Mir, Bruno Le Pioufle. A technique to design complex 3D lab on a chip involving multilayered fluidics, embedded thick electrodes and hard packaging. Application to dielectrophoresis and electroporation of cells.. Journal of Micromechanics and Microengineering, IOP Publishing, 2010, 20, pp.047001. ⟨10.1088/0960-1317/20/4/047001⟩. ⟨hal-00592400⟩
  • Toshihisa Osaki, Hiroaki Suzuki, Bruno Le Pioufle, Shoji Takeuchi. Multichannel Simultaneous Measurements of Single-Molecule Translocation in α-Hemolysin Nanopore Array. Analytical Chemistry, American Chemical Society, 2009, 81 (24), pp.9866-9870. ⟨10.1021/ac901732z⟩. ⟨hal-00599956⟩
  • Hiroaki Suzuki, Bruno Le Pioufle, Shoji Takeuchi. Ninety-six-well planar lipid bilayer chip for ion channel recording Fabricated by hybrid stereolithography. Biomedical Microdevices, Springer Verlag, 2009, 11 (1), pp.17-22. ⟨10.1007/s10544-008-9205-4⟩. ⟨hal-00599926⟩
  • Bassam Hajj, Sophie de Reguardati, Loic Hugonin, Bruno Le Pioufle, Toshihisa Osaki, et al.. Electro-Optical Imaging Microscopy of Dye-Doped Artificial Lipidic Membranes. Biophysical Journal, Biophysical Society, 2009, 97 (11), pp.2913-2921. ⟨10.1016/j.bpj.2009.08.055⟩. ⟨hal-00599955⟩
  • Peter Low, Bruno Le Pioufle, Beomjoon Kim, Christian Bergaud. Assembly of CdSe/ZnS nanocrystals on microwires and nanowires for temperature sensing. Sensors and Actuators B: Chemical, Elsevier, 2008, 130 (1), pp.175-180. ⟨10.1016/j.snb.2007.07.123⟩. ⟨hal-00599950⟩
  • Bruno Le Pioufle, H. Suzuki, K. Tabata, H. Noji, S. Takeuchi. Lipid Bilayer Microarray for Parallel Recording of Transmembrane Ion Currents. Analytical Chemistry, American Chemical Society, 2008, 80 (1), pp.328-332. ⟨10.1021/ac7016635⟩. ⟨hal-00599949⟩
  • E. Leclerc, B. David, L. Griscom, Bruno Le Pioufle, T. Fujii, et al.. Perfusion culture of mammalian cells in microfluidic environments for tissue engineering applications.. La Houille Blanche - Revue internationale de l'eau, EDP Sciences, 2006, 3, pp.56-59. ⟨hal-00090259⟩
  • E. Leclerc, B. David, L. Griscom, Bruno Le Pioufle, T. Fujii, et al.. Study of osteoblastic cells in a microfluidic environment. Biomaterials, Elsevier, 2006, 27 (4), pp.586-595. ⟨10.1016/j.biomaterials.2005.06.002⟩. ⟨hal-02149853⟩
  • E. Leclerc, B. David, L Griscom, Bruno Le Pioufle, T. Fujii, et al.. Study of Osteoblastic Cells in a Microfluidic Environment. Biomaterials, Elsevier, 2006, 27 (4), pp.558-595. ⟨hal-00778216⟩
  • Eric Leclerc, Bertrand David, Laurent Griscom, Bruno Lepioufle, Yasuyuki Sakai, et al.. Perfusion culture of mammalian cells in microfluidic environments for tissue engineering applications . La Houille Blanche - Revue internationale de l'eau, EDP Sciences, 2006, pp.56-59. ⟨10.1051/lhb:200603008⟩. ⟨hal-02149903⟩
  • F Morin, N. Nishimura, L Griscom, Bruno Le Pioufle, H Fujita, et al.. Constraining the connectivity of neuronal networks cultured on microelectrodes arrays with microfluidic techniques: a step towards neuron-based functional chips". Biosensors and Bioelectronics, Elsevier, 2006, 21 (7), pp.1093-1100. ⟨hal-00739218⟩
  • Matthieu Denoual, Y. Macé, Bruno Le Pioufle, Pascal Mognol, D. Castel, et al.. Vacuum Casting to Manufacture a Plastic Biochip for Highly Parallel Cell Transfection. Measurement Science and Technology, IOP Publishing, 2006, 17, pp.3134-3140. ⟨10.1088/0957-0233/17/12/S03⟩. ⟨hal-00739220⟩
  • Matthieu Denoual, M. Chiral, Bruno Le Pioufle. Cell Cultures over Nanoneedle Fields. Nanobiotechnology Journal, 2005, 1 (4), pp.389-394. ⟨10.1385/nbt:1:4:389⟩. ⟨hal-00739221⟩
  • Matthieu Denoual, Pascal Mognol, Bruno Le Pioufle. Vacuum casting, a new answer to manufacture biomicrosystems. Journal of Engineering Manufacture, 2005, 219 (9), pp.697-502. ⟨10.1243/095440505X32571⟩. ⟨hal-00739222⟩
  • Bruno Le Pioufle, Marie Frenea-Robin, A. Tixier. Parallel cell biochips: cell placement using dielectrophoresis or microfluidic effects. Comptes Rendus Physique, Centre Mersenne, 2004, 5 (5), pp.589-596. ⟨hal-00141373⟩
  • Marie Frénéa, Bruno Le Pioufle. Micromanipulation de particules polarisables par diélectrophorèse. Revue Internationale de Génie Electrique, 2004, 7 (3-4), pp.419-431. ⟨10.3166/rige.7.419-431⟩. ⟨hal-00794466⟩
  • M. Frenea, S. P. Faure, Bruno Le Pioufle, P. Coquet, H. Fujita. Positioning living cells on a high-density electrode array by negative dielectrophoresis. Materials Science and Engineering: C, Elsevier, 2003, 23 (5), pp.597-603. ⟨hal-00739225⟩
  • Bruno Le Pioufle, M. Frénéa, A. Tixier. Biopuces pour le traitement électrique paraléllisé de cellules. Journal sur l'enseignement des sciences et technologies de l'information et des systèmes, EDP Sciences, 2003, 2 (HORS SÉRIE 2), pp.6. ⟨10.1051/bib-j3ea:2003608⟩. ⟨hal-00739226⟩
  • Laurent Griscom, Patrick Degenaar, Bruno Le Pioufle, Eiichi Tamiya, Hiroyuki Fujita. Techniques for patterning and guidance of primary culture neurons on micro-electrode arrays. Sensors and Actuators B: Chemical, Elsevier, 2002, 83 (1-3), pp.15-21. ⟨hal-00778213⟩
  • Patrick Surbled, Catherine Clerc, Bruno Le Pioufle, Manabu Ataka, Hiroyuki Fujita. Effect of the composition and thermal annealing on the transformation temperatures of sputtered TiNi shape memory alloy thin films. Thin Solid Films, Elsevier, 2001, 401 (1-2), pp.52-59. ⟨hal-00739227⟩
  • L. Griscom, P. Degenaar, Bruno Le Pioufle, E. Tamiya, H. Fujita. Cell Placement and Neural Guidance Using a Three-Dimensional Microfluidic Array. Japanese Journal of Applied Physics, Japan Society of Applied Physics, 2001, 40, pp.5485-5490. ⟨hal-00778212⟩
  • P. Degenaar, Bruno Le Pioufle, L. Griscom, A. Tixier, Y. Akagi, et al.. A Method for Micrometer Resolution Patterning of Primary Culture Neurons for SPM Analysis. Journal of Biochemistry, Oxford University Press (OUP), 2001, 130, pp.367-376. ⟨hal-00786168⟩
  • Bruno Le Pioufle, P. Surbled, H. Nagai, Y. Murakami, H. S. Chun, et al.. Living cells captured on a bio-microsystem devoted to DNA injection. Materials Science and Engineering: C, Elsevier, 2000, 12 (1-2), pp.77-81. ⟨hal-00739228⟩
  • P. Surbled, C. Clerc, Bruno Le Pioufle, H. Fujita. Characterization of sputtered TiNi shape memory alloy thin films. Japanese Journal of Applied Physics, Japan Society of Applied Physics, 1999, 38, pp.L1547-L1549. ⟨10.1143/JJAP.38.L1547⟩. ⟨in2p3-00003942⟩
  • Bruno Le Pioufle, J. F. Fauvarque, P. Delalande. Comportement non linéaire des générateurs électrochimiques associés aux convertisseurs statiques. Détection de l'état de charge. European Physical Journal: Applied Physics, EDP Sciences, 1998, 2 (03), pp.257-265. ⟨10.1051/epjap:1998191⟩. ⟨hal-00778215⟩
  • D. Grenier, L. A. Dessaint, O. Akhrif, Y. Bonnassieux, Bruno Le Pioufle. Experimental nonlinear torque control of a permanent-magnet synchronous motor using saliency. IEEE Transactions on Industrial Electronics, Institute of Electrical and Electronics Engineers, 1997, 44 (5), pp.680-687. ⟨10.1109/41.633471⟩. ⟨hal-00778211⟩
  • H. Cailleux, Bruno Le Pioufle, B. Multon. COMPARISON OF CONTROL STRATEGIES TO MINIMIZE THE TORQUE RIPPLE OF A SWITCHED RELUCTANCE MACHINE. Electric Machines and Power Systems, Informa UK (Taylor & Francis), 1997, 25 (10), pp.1103-1118. ⟨10.1080/07313569708955800⟩. ⟨hal-00778210⟩
  • H. Cailleux, Bruno Le Pioufle, Bernard Multon. Modélisation et commande non linéaire en couple d'une machine à réluctance variable à double saillance. Journal de Physique III, EDP Sciences, 1996, 6 (1), pp.55-75. ⟨10.1051/jp3:1996114⟩. ⟨jpa-00249447⟩
  • J.-F. Liebaut, Bruno Le Pioufle. Onduleur MLI pour servomoteur synchrone: minimisation des pulsations de couple. RGE, 1994. ⟨hal-00778217⟩
  • Bruno Le Pioufle. COMPARISON OF SPEED NONLINEAR CONTROL STRATEGIES FOR THE SYNCHRONOUS SERVOMOTOR. Electric Machines and Power Systems, Informa UK (Taylor & Francis), 1993, 21 (2), pp.151-169. ⟨10.1080/07313569308909644⟩. ⟨hal-00778214⟩
  • Bruno Le Pioufle, G. Georgiou, J.-P. Louis. A robust total compensation algorithm for the torque control of a synchronous servomotor. Journal de Physique III, EDP Sciences, 1992, 2 (1), pp.129-144. ⟨10.1051/jp3:1992115⟩. ⟨jpa-00248724⟩
  • Bruno Le Pioufle, G. Georgiou. Commande non linéaire en vitesse d'un servomoteur synchrone avec calcul de trajectoire et estimation du couple résistant. Journal de Physique III, EDP Sciences, 1992, 2 (10), pp.1905-1924. ⟨10.1051/jp3:1992221⟩. ⟨jpa-00248854⟩
  • Bruno Le Pioufle, G. Georgiou, J.-P. Louis. Application des commandes non linéaires pour la régulation en vitesse ou en position de la machine synchrone autopilotée. Revue de Physique Appliquée, Société française de physique / EDP, 1990, 25 (6), pp.517-526. ⟨10.1051/rphysap:01990002506051700⟩. ⟨jpa-00246214⟩

Conference papers98 documents

  • Tieying Xu, Maria Lizarralde-Iragorri, Jean Roman, Emile Martincic, Valentine Brousse, et al.. A microfluidic device to statistically determine the distribution of sickle red cell subpopulations using bioimpedance. Transducers, 2021, on-line, France. ⟨hal-03260796⟩
  • Izadora Mayumi Fujinami Tanimoto, Benjamin Cressiot, Jean Roman, Nathalie Jarroux, Gilles Patriarche, et al.. Nanoparticle detection by solid state nanopore integrated into a reusable microfluidic device. MicroTAS, Oct 2020, on-line, France. ⟨hal-03031395⟩
  • Tieying Xu, Maria Lizarralde-Iragorri, Jean Roman, Emile Martincic, Valentine Brousse, et al.. Electrical Sensing of sickled red blood cells subpopulations in microfluidic device. MicroTAS, Oct 2020, on-line, France. ⟨hal-03078878⟩
  • Yu-Sheng Lin, Bruno Le Pioufle, Hsiang-Yu Wang. Monitoring the growthphases of microalgae using straightforward dielectrophoresis measurements. MicroTAS, Oct 2020, on-line, France. ⟨hal-03078861⟩
  • Thao Mai, Sakina Bensalem, Bénédicte Thiebot, Philippe Manivet, Juan Pelta, et al.. Characterizing single sinonasal squamous cell carcinoma using dielectrophoresis and electrorotation. MicroTAS, Oct 2020, on-line, France. ⟨hal-03078871⟩
  • Xu Tieying, Maria Lizarralde, Jean Roman, Wassim El Nemer, Bruno Le Pioufle, et al.. Electrical Detection of the Mechanical Alteration of Sickling Red Blood Cells within a Microfluidic Capillary Network. MicroTAS, Oct 2019, Basel, Switzerland. ⟨hal-02387976⟩
  • Yuki Okamoto, Taku Tsuchiya, Charles Moslonka, Yu-Sheng Lin, Sung Tsang, et al.. Z-Axis Controllable Mille-Feuille electrode electrorotation device utilizing levitation effect. Transducers 2019 - EUROSENSORS XXXIII, Jun 2019, Berlin, Germany. ⟨hal-02151887⟩
  • Houssein Mariam, Patrick Poulichet, Hakim Takhedmit, Rousseau Lionel, Bruno Le Pioufle, et al.. Puce microfluidique instrumentée pour la caractérisation HyperFréquence de fluides par spectroscopie diélectrique. C2i 2019 : 8ème Colloque Interdisciplinaire en Instrumentation, Jan 2019, Talence, France. ⟨hal-02151546⟩
  • Sakina Bensalem, Pierre Bodenes, Olivier Français, Dominique Pareau, Filipa Lopes, et al.. Characterization of Chlamydomonas Reinhardtii's cell wall and membrane permeability after PEF treatment and mechanical compressions within a microfluidic device. 3rd World Congress on Electroporation, Sep 2019, Toulouse, France. ⟨hal-02285033⟩
  • Manon Boul, Satomi Matsumoto, Marie Shinohara, Yasuyuki Sakai, Teruo Fujii, et al.. Sensing of Oxygen Concentration in a Microfluidic Device mimicking Liver 3D Microarchitecture. MicroTAS, Oct 2019, Basel, Switzerland. ⟨hal-02387492⟩
  • Yu-Sheng Lin, Sung Tsang, Sakina Bensalem, Filipa Lopes, Chen-Li Sun, et al.. Using dielectrophoresis and electrorotation techniques to assess the dielectric properties of Scenedesmus Abundans at different growth states. microTAS, Nov 2018, Kaohsiung, Taiwan. ⟨hal-01959748⟩
  • Manon Boul, Nassima Benzoubir, Nassim Arouche, Rasta Ghasemi, Jean-Pierre Lefevre, et al.. Comparison of serial and parallelized microfluidic structures mimicking hepatic cords and liver sinusoids on a chip. Organ-on-a-Chip & Tissue-on-a-Chip EUROPE 2018, Jun 2018, Rotterdam, Netherlands. ⟨hal-01991331⟩
  • Xu Tieying, Maria Lizarralde, Wassim El Nemer, Bruno Le Pioufle, Olivier Français. Microfluidic device using reusable parylen-pdms packaging for the red blood cell transit time analysis in mechanical constrictions, using impedance measurement. MicroTAS, Nov 2018, Kaohsiung, Taiwan. ⟨hal-01972640⟩
  • Yu-Sheng Lin, Sung Tsang, Rasta Ghasemi, Sakina Bensalem, Olivier Français, et al.. Dielectric Characterisation of Single Microalgae Cell Using Electrorotation Measurements. Eurosensors 2017, Sep 2017, Paris, France. pp.543 - 6, ⟨10.3390/proceedings1040543⟩. ⟨hal-01592123⟩
  • Clyde Midelet, J.-Y. Lin, Sung Tsang, Chen-Li Sun, Johanna Midelet, et al.. Effects of biomolecules on the electrokinetics of colloidal nanoparticles in liquid suspension. SPIE BIOS, Jan 2017, San Francisco, CA, United States. pp.100780T, ⟨10.1117/12.2252470⟩. ⟨hal-01501667⟩
  • Bruno Le Pioufle, Olivier Français. Mechanical and Electrical sensing of single biological cell properties within microfluidic devices. NEMS (Nano Engineering Molecular Systems), Apr 2017, Los-Angeles, United States. ⟨hal-01515021⟩
  • Tieying Xu,, Maria Lizarralde,, Wassim El Nemer, Bruno Le Pioufle, Olivier Français. Monitoring Biological Cell Flow within a Mimicking Capillary Device with Impedance Measurement. Eurosensors, Sep 2017, Paris, France. pp.3 - 6, ⟨10.3390/proceedings1040517⟩. ⟨hal-01592142⟩
  • Abdelhatif El Fellahi, Thierry Bore, Lionel Rousseau, Bruno Le Pioufle, Olivier Français. Microwave Sensor within a Microfluidic Chip for Biological Applications. Eurosensors, Sep 2017, Paris, France. pp.523, ⟨10.3390/proceedings1040523⟩. ⟨hal-01592115⟩
  • Jean Roman, Olivier Français, Nathalie Jarroux, Gilles Patriache, Juan Pelta,, et al.. Nanoparticle electrical analysis and detection with a solid-state nanopore in a microfluidic device. Eurosensors 2016, Sep 2016, Budapest, Hungary. ⟨hal-01390031⟩
  • Abdelhatif El Fellahi, Thierry Bore, Pierre Bodénès, Sakina Bensalem, Bruno Le Pioufle, et al.. RF characterization of intracellular microalgae lipids. Eurosensors 2016, Sep 2016, Budapest, Hungary. pp.1287-1290, ⟨10.1016/j.proeng.2016.11.449⟩. ⟨hal-01368312⟩
  • Pierre Bodénès, Filipa Lopes, Dominique Pareau, Olivier Français, Bruno Le Pioufle. A Microfluidic Device for the Real-Time Characterization of Lipid Producing Algae Cell Population Submitted to a Pulsed Electric Field. 1st World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food & Environmental Technologies, Sep 2015, Portorož, Slovenia. pp.409-413, ⟨10.1007/978-981-287-817-5_89⟩. ⟨hal-01222446⟩
  • Pierre Bodénès, Sakina Bensalem, Filipa Lopes, Dominique Pareau, Olivier Français, et al.. In situ and real time electroporation of a lipid producing microalgae in a microfluidic device. Algae Europe 2015, Dec 2015, Lisbonne, Portugal. ⟨hal-01275167⟩
  • Franz Bozsak, Bruno Carreel, Pierluca Massina, Myline Cottance, Olivier Français, et al.. First in vivo results of an innovative sensor to detect stent-related complications. ICI 2015, Dec 2015, Tel-Aviv, Israel. ⟨hal-01275165⟩
  • Olivier Français, Bruno Le Pioufle. Microfluidic devices for the cell sensing and treatment. GLEAM'15, Jun 2015, Cachan, France. ⟨hal-01222696⟩
  • Lionel Rousseau, Gaelle Lissorgues, Fikar Pavel, Olivier Français, Bruno Le Pioufle, et al.. SU-8 microchannels for live cell dielectrophoresis improvements. DTIP 2015, Apr 2015, Montpellier, France. ⟨hal-01159000⟩
  • Claudia Irene Trainito, Emilie Bayart, Emilie Bisceglia, Frédéric Subra, Olivier Français, et al.. Electrorotation as a Versatile Tool to Estimate Dielectric Properties of Multi-scale Biological Samples: from Single Cell to Spheroid Analysis. 1st World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food & Environmental Technologies, Sep 2015, Portoroz, Slovenia. pp.75-78. ⟨hal-01222447⟩
  • Agnes Tixier, Takuya Takahashi, Hiroyuki Fujita, H. Toshiyoshi, Isao Mori, et al.. Detection of Micro-Beads by Impedance Cytometry - Towards a Wholly Integrated Electronic Device for Biological Cells Applications. Symposium on Design, Test, Integration ans Packaging of MEMS/MOEMS, Apr 2014, Cannes, France. pp.1-6. ⟨hal-00987015⟩
  • Agnes Tixier, E. Lebrasseur, T. Takahashi, Olivier Français, Bruno Le Pioufle, et al.. Compressively-Stressed Test Structures for Opaque Micro-Structures Releasing Visualization. International Conference on Microelectronic Test Structures, Mar 2014, Udine, Italy. pp.170-173. ⟨hal-00987105⟩
  • Rémi Sieskind, Claudia Trainito, Olivier Français, Bruno Le Pioufle. Microsystème dédié à l’étude de la polarisation diélectrique de micro-particules dans le cadre de formation master recherche : application au micro-positionnement 3D de cellules par force de diélectrophorèse. CETSIS 2014 : Enseignement des Technologies et de Sciences de l'Information et des Systèmes, Oct 2014, Besançon, France. ⟨hal-01085282⟩
  • Claudia Trainito, Olivier Français, Bruno Le Pioufle. Monitoring in real time the dielectric properties of a single cell combining dielectrophoresis and electrorotation experiments in a microfluidic device : towards electropermeabilization analysis. Dielectrophoresis 2014, Jul 2014, United Kingdom. ⟨hal-01026163⟩
  • Olivier Français, Bruno Le Pioufle. Apport des microtechnologies pour l’étude des propriétés diélectriques cellulaires : application au tri et à la capture de cellules biologiques en environnement microfluidique. Congrès Annuels conjoints de la Société Français d'Immunologie (SFI) et de l'Association Française de Cytométrie (AFC), Nov 2014, Lille, France. ⟨hal-01085273⟩
  • Olivier Français, Bruno Le Pioufle, Claudia Trainito. Etude et mise en oeuvre d’un microsystème fluidique pour la caractérisation diélectrique de cellules biologiques par électrorotation. Symposium de Génie Electrique, Jul 2014, Cachan, France. ⟨hal-01076066⟩
  • Claire Dalmay, Emilie Bisceglia, Feriel Hamdi, Olivier Français, Bruno Le Pioufle. Micro-nanotechnologies pour l’analyse et le traitement parallèle de cellules ou de protéines sur puce. Symposium de Génie Electrique, Jul 2014, Cachan, France. ⟨hal-01076067⟩
  • Claudia Trainito, Olivier Français, Bruno Le Pioufle. A microfluidic device to determine dielectric properties of a single cell : a combined dielectrophoresis and electrorotation technique. 4th European Conference on Microfluidics, Dec 2014, Limerick, Ireland. ⟨hal-01096921⟩
  • Wassim El Nemer, Papa Alioune Ndour, Sophie D. Lefevre, Harvey Tawfik, Julien Picot, et al.. A microfluidic device to study red blood cell deformability. 4th European Conference on Microfluidics, Dec 2014, Limerick, Ireland. ⟨hal-01113061⟩
  • Bertrand David, Eric Perrin, Lazaar Mélanie, Chabanon Morgan, Bruno Le Pioufle, et al.. Reproducing topography and roughness of osteoconductive materials in a microfluidic device for bone tissue engineering. 4th European Conference on Microfluidics, Dec 2014, Limerick, Ireland. ⟨hal-01096932⟩
  • Martinus H. V. Werts, Vincent Raimbault, Matthieu Loumaigne, Laurent Griscom, Olivier Français, et al.. Optical microscopy and spectroscopy of analyte-sensitive functionalized gold nanoparticles in microfluidic systems. Proc. SPIE 2013, 8595, 85950W, Feb 2013, United States. pp.85950W, ⟨10.1117/12.2001608⟩. ⟨hal-00809421v2⟩
  • Angélique Coutable, Vincent Noireaux, Bruno Lepioufle, Olivier Français, Christophe Vieu, et al.. Insertion of functional proteins into bilayer lipid membrane using a cell-free expression system. 57. Annual Meeting of the Biophysical Society, Feb 2013, Philadelphie, Pennsylvanie, United States. pp.548A, ⟨10.1016/j.bpj.2012.11.3039⟩. ⟨hal-01268382⟩
  • Feriel Hamdi, Wei Wang, Frédéric Subra, Elisabeth Dufour-Gergam, Olivier Français, et al.. High Density Cell Electrofusion on Chip Using an Array of Non-Connected Metallic Pads. Biodevices, 2013, Barcelone, Spain, Spain. pp.68-72. ⟨hal-00790205⟩
  • Agnes Tixier, Isao Mori, T. Takahashi, Olivier Français, Bruno Le Pioufle, et al.. Micro-fluidic channel integration on thick-SOI LSI device for cells analyses. Sensor Symposium 2013, Nov 2013, Sendaï, Japan. pp.320-325. ⟨hal-00987092⟩
  • Bruno Le Pioufle, Claire Dalmay, Olivier Français. Design and use of microfluidic devices for the real time monitoring of micro/nanopulses effect on cells. Bioelectrochemistry 2013, Mar 2013, Bochum, Germany. pp.80. ⟨hal-00805500⟩
  • Olivier Français, Bruno Le Pioufle. La mesure de la bio-impédance d'un végétal comme moyen d'introduire le domaine de la biologie dans une formation E.E.A.. Colloque sur l'Enseignement des Technologies et des Sciences de l'Information et des Systèmes (CETSIS), Mar 2013, Caen, France. pp.199 - 203. ⟨hal-00804673⟩
  • Martinus H. V. Werts, Matthieu Loumaigne, Julien R. G. Navarro, A. Débarre, Laurent Griscom, et al.. Quenched fluorescence and enhanced resonant light scattering in molecular plasmonic assemblies. Molecular Plasmonics 2013, May 2013, Jena, Germany. ⟨hal-00877127⟩
  • Martinus H. V. Werts, Matthieu Loumaigne, Julien R. G. Navarro, Anne Débarre, Laurent Griscom, et al.. Quenched fluorescence and enhanced resonant light scattering in molecular plasmonic assemblies. International Conference on Photochemistry 2013, Jul 2013, Belgium. ⟨hal-00877131⟩
  • M. Chabanon, H. Duval, O. Francais, Bruno Le Pioufle, E. Vennat, et al.. In vitro and in silico study of cell growth in porous scaffold under dynamic flow. 3rd TERMIS World Congress 2012 - Vienna, Austria, Sep 2012, Vienna, Austria. pp.340-341. ⟨hal-00741428⟩
  • Martinus H. V. Werts, Julien R. G. Navarro, Laurent Griscom, Olivier Français, Bruno Le Pioufle, et al.. From fluorescence quenching by metal nanoparticles to enhanced spectroscopic detection in microfluidic volumes. 1st International Conference on Enhanced Spectroscopy, Oct 2012, Porquerolles, France. ⟨hal-00753361⟩
  • Emilie Bisceglia, Myriam Cubizolles, Frédéric Mallard, Olivier Français, Bruno Le Pioufle. Dielectrophoretic separation of blood pathogens ou Bacterial extraction from biological samples using DEP forces. lab on a chip world congress, Sep 2012, San Diego, United States. pp.1. ⟨hal-00786577⟩
  • Claire Dalmay, Olivier Français, Frédéric Subra, Bruno Le Pioufle. Insulated gold micro singularities for high density cell trapping based on dielectrophoresis. Nanobiotech, 2011, Montreux, Switzerland. ⟨hal-00739186⟩
  • S Michelet, J-P Barbot, O Francais, P.Y. Joubert, Pascal Larzabal, et al.. Towards a Statistical Description of Experimental Data for Detection - Estimation problems in DNA translocations trhough nanopores. BIOSIGNALS, 2011, Roma, Italy. ⟨hal-00739181⟩
  • Marie-Amélie de Ménorval, Franck André, Aude Silve, Claire Dalmay, O. Francais, et al.. Development and uses of a microfluidic chamber to apply microsecond and nanosecond electric pulses and to visualize biological effects induced. Pôle Lorrain de l'Ingéniérie du Cartilage, Sep 2011, Nancy, France. pp.1. ⟨hal-00933141⟩
  • M.A. de Menorval, F Andre, Aude Silve, Claire Dalmay, O Francais, et al.. Development and uses of a microfluidic chamber to apply microsecond or nanosecond electric pulses and to visualize biological effects induced.. PLIC - Electroporation based Technologies and Treatments, 2011, Lubjana, Slovenia. ⟨hal-00739184⟩
  • Fériel Hamdi, Olivier Français, Marion Woytasik, Elisabeth Dufour-Gergam, Bruno Le Pioufle. Self control of cell electroporation by dielectrophoresis transition. Nanobiotech, 2011, Montreux, Switzerland. ⟨hal-00739183⟩
  • Marie-Amélie de Ménorval, Franck André, Aude Silve, Claire Dalmay, Olivier Français, et al.. Development and uses of a microfluidic chamber to apply microsecond or nanosecond electric pulses and to visualize biological effects induced. Electroporation based Technologies and Treatments, Nov 2011, Ljubljana, Slovenia. pp.1. ⟨hal-00933139⟩
  • Claire Dalmay, Olivier Français, Bruno Le Pioufle. Array of Metallic Singularities for the high density cell Placement on a Microfluidic Chip. MMB, 2011, Lucerne, Switzerland. ⟨hal-00739187⟩
  • Feriel Hamdi, Olivier Français, Julien Villemejane, M Woytasik, Claire Dalmay, et al.. A Microfluidic Biochip Dedicated to Highly Parallelized Electrofusion. MMB, 2011, Lucerne, Switzerland. ⟨hal-00739182⟩
  • Marie-Amélie de Ménorval, Franck Andre, Aude Silve, Claire Dalmay, Olivier Français, et al.. Dispositifs microfluidiques pour l'exposition et l'observation de cellules biologiques exposées à des impulsions électriques nanosecondes. Journées Nationales des Nanotechnologies et des Nanosciences, J3N, Nov 2011, Strasbourg, France. pp.1. ⟨hal-00933138⟩
  • Claire Dalmay, Yung-Yung Lai, Laurent Griscom, Olivier Français, Bruno Le Pioufle, et al.. Positioning and orientation of adherent cells in a microfluidic chip using the micro patterning of a parylen-C-film. biodevices, 2011, Rome, Italy. ⟨hal-00739185⟩
  • Toshihisa Osaki, Jean-Pierre Barbot, Ryuji Kawano, Hirotaka Sasaki, Olivier Français, et al.. A Rupture Detection Algorithm for the DNA Translocation Detection Though Biological Nanopore. Eurosensors, 2010, Linz, Austria. ⟨hal-00739190⟩
  • Claire Dalmay, J Villemejane, O Français, M Woytasik, E Dufour-Gergam, et al.. Thick Electrode Biochip for in Vitro Studies of the Nanoporation of Living Cells. Microfluidics, 2010, Toulouse, France. ⟨hal-00739191⟩
  • J Villemejane, G Mottet, O Français, Jp Lefèvre, M Woytasik, et al.. Nanomanipulation of living cells on a chip using electric field: general concepts and microdevices. DELTA, 2010, Ho-shi-minh, Vietnam. ⟨hal-00739188⟩
  • N Pham Van, J Villemejane, F Hamdi, G Mottet, Claire Dalmay, et al.. A High Density Microfluidic Device for Cell Pairing and Electrofusion. Eurosensors, 2010, Linz, Austria. ⟨hal-00739189⟩
  • B. Hajj, S. de Reguardati, L. Hugonin, T. Osaki, H. Suzuki, et al.. Electro-Optical Imaging Microscopy of Dye Doped Lipid Bilayer. 2009 Conference on Lasers and Electro-Optics and Quantum Electronics and Laser Science Conference, 2009, Germany. pp.3-4. ⟨hal-00795108⟩
  • O Français, G Mottet, A Ayina, Bruno Le Pioufle. 3D field focusing and defocusing geometries for cell trapping on a chip. DTIP, 2009, Roma, Italy. ⟨hal-00739193⟩
  • O. Francais, A Ayina, J Villemejane, L Rousseau, L Mir, et al.. High Density Cell Microarray Based on Dielectrophoresis Traps Induced by a Matrix of Singularities. MicroTAS, 2009, North Korea. ⟨hal-00739196⟩
  • J Villemejane, V. Joubert, O Français, Bruno Le Pioufle, Lm Mir. Nanosecond electric pulses-induced enhancement of reporter gene expression after electrotransfer in skeletal muscle in vivo. Int. Bioelectric Symposium, 2009, France. ⟨hal-00739192⟩
  • O Français, B Mahe, A Dimitracopoulos, Mc Julien, Jp Lefevre, et al.. Digital concentration gradient generators on a microfluidic chip. DTIP, 2009, Rome, Italy. ⟨hal-00739194⟩
  • O Francais, A Dimitracopoulos, Jp Lefevre, F Subra, Jf Mouscadet, et al.. Fast concentration gradient generator on a cell biochip for toxicology applications. MicroTAS, 2009, France. ⟨hal-00739195⟩
  • T Osaki, H Suzuki, Bruno Le Pioufle, S Takeuchi. Multichannel Nanopore for High Throughput Single Molecule Detection. MicroTAS, 2008, North Korea. ⟨hal-00739198⟩
  • G Mottet, J Villemejane, J.P. Lefevre, Bruno Le Pioufle. A complete process to make a lab on a chip with complex fluidics and thick electrodes for biological applications. European Conference on Microfluidics, 2008, Bologne, Italy. ⟨hal-00739199⟩
  • J Villemejane, G Mottet, O Français, J.P. Lefevre, L.M. Mir, et al.. Insulated Liquid Electrodes in a microfluidic chip for the electroporation of living cells. European Conference on Microfluidics, 2008, Bologna, Italy. ⟨hal-00739197⟩
  • Marie Frenea-Robin, Julie Laforet, G. Robin, Bruno Le Pioufle, Laurent Nicolas. Selecting an electrode structure for cell sorting by differential dielectric affinity. 29th IEEE EMBC, Aug 2007, Lyon, France. pp.6311-6314, ⟨10.1109/IEMBS.2007.4353798⟩. ⟨hal-00412972⟩
  • Y. H. Cho, S. W. Lee, Bruno Le Pioufle, N. Takama, S. Takeuchi, et al.. High-throughput single-cell electroporation microchip with three dimensional si microelectrodes for gene transfection. Transducers '07 & Eurosensors Xxi, Digest of Technical Papers, Vols 1 and 2, 2007, France. pp.U474-U475. ⟨hal-00795167⟩
  • Matthieu Denoual, Magali Chiral, Olivier de Sagazan, Bruno Le Pioufle. Nanoneedle fields for biological interaction with cells. Proc. of Micro Total Analysis System (uTAS), Japan, 2006, 2006, Japan. pp 1-9. ⟨hal-00986481⟩
  • E. Leclerc, L. Griscom, Bruno Le Pioufle, C. Guguen-Guillouzo, A. Corlu, et al.. Investigation of Human Hepatoma cell line microfluidic devices.. 3rd annual International IEEE EMBS special topic conference on microtechnologies in medicine and biology., 2005, Oahu, Hawaii, United States. ⟨hal-00019381⟩
  • E. Leclerc, B. David, R. Warocquier-Clerout, L. Griscom, Bruno Le Pioufle, et al.. Behaviour of osteoblast-like cells in cellular microdevices. Micro Total Analysis Systems 2004, Vol 1, 2005, Netherlands. pp.396-398. ⟨hal-00795188⟩
  • Olivier de Sagazan, Matthieu Denoual, P. Guil, D. Gaudin, Bruno Le Pioufle, et al.. Horizontal buried channels in monocrystalline silicon. Conf. Proc. of DTIP of MOEMS & MEMS 2005, May 2005, Montreux, Switzerland. pp.351-354. ⟨hal-00775898⟩
  • E. Leclerc, L. Griscom, Bruno Le Pioufle, C. Guguen-Guillouzo, A. Corlu, et al.. Investigation of human hepatoma cell line in microfluidic devices. 2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology, 2005, Shanghai, China. pp.385-388, ⟨10.1109/mmb.2005.1548482⟩. ⟨hal-00795183⟩
  • L. Griscom, G. Legeay, Bruno Le Pioufle. Surface engineering of microfluidic systems for cellular biochips. 2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology, 2005, China. pp.194-197, ⟨10.1109/mmb.2005.1548424⟩. ⟨hal-00795194⟩
  • Matthieu Denoual, Magali Chiral, Olivier de Sagazan, Bruno Le Pioufle. Cell Cultures over Nanoneedle Fields Euronanoforum. Euronanoforum, Nanotechnology and the Health of EU Citizen, 2005, United Kingdom. ⟨hal-00986470⟩
  • L. Griscom, Y. Chateau, J. P. Pennec, Laurent Misery, Bruno Le Pioufle. Co-culture of cells in PDMS microsystem for sensitized artificial skin. 2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology, 2005, China. pp.184-187, ⟨10.1109/mmb.2005.1548421⟩. ⟨hal-00795208⟩
  • L. Griscom, Y. Chateau, J. P. Pennec, Laurent Misery, Bruno Le Pioufle. Microsystems for dermatological research. Journal of Investigative Dermatology, 2005, Australia. pp.A20-A20. ⟨hal-00795213⟩
  • Magali Chiral, Matthieu Denoual, Antonin Hoël, Jimmy Aguinet, Bruno Le Pioufle. Electrotransfection results on Jurkat cells on a microdevice. Angioskin, Electroporation based Technologies and Treatments workshop, Slovenia, 2005, 2005, Slovenia. ⟨hal-00986477⟩
  • Matthieu Denoual, S. Prioux, Y. Mace, Pascal Mognol, Bruno Le Pioufle. Vacuum casting of low-cost polymer microstructures for bio-chemical microsystems applications. Micro Total Analysis Systems 2004, Vol 2, 2005, Netherlands. pp.357-359. ⟨hal-00795218⟩
  • A. Tixier-Mita, J. Jun, M. Chiral, S. Ostrovidov, Marie Frenea-Robin, et al.. A silicon micro-system for parallel gene transfection into arrayed cells. 8th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Sep 2004, Malmo, Sweden. pp.180-182. ⟨hal-00412979⟩
  • Marie Frenea-Robin, M. Chiral, Bruno Le Pioufle, Nathalie Melaine, Charles Pineau, et al.. On-chip spermatozoa trapping by dielectrophoresis. 8th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Sep 2004, Malmo, Sweden. pp.111-113. ⟨hal-00412976⟩
  • Olivier de Sagazan, Matthieu Denoual, P. Guil, D. Gaudin, Bruno Le Pioufle, et al.. Horizontal buried channels in monocrystalline silicon. Proceeding of the MEMS 2004 conference, Jan 2004, Maastricht, Germany. pp.661-664. ⟨hal-00847215⟩
  • R. Piron, N. Rougier, R. Vaudry, A. Corlu, D. Glaise, et al.. On-a-chip genotoxicity assay-application to high-throughput screening biochips. Micro Total Analysis Systems 2004, Vol 1, 2004, Dordrecht, Netherlands. pp.527-529. ⟨hal-00795175⟩
  • Matthieu Denoual, Olivier de Sagazan, Patrice Guil, Bruno Le Pioufle. Driving Liquids with Thermal Actuators. Proc. of Actuator, 9th conference, Bremen, 2004, Germany. pp 1-9. ⟨hal-00986466⟩
  • Matthieu Denoual, Pascal Mognol, Bruno Le Pioufle. Exploring the Limits of Vacuum Casting Technique for Micron and Submicron Features. Proc. of Solid Freeform Symposium, 2004, United States. pp 1-9. ⟨hal-00986465⟩
  • Laurent Griscom, Patrick Degenaar, Matthieu Denoual, Fabrice Morin, Bruno Le Pioufle, et al.. Culturing of Neurons in Microfluidic Arrays. 2nd IEEE-EMBS Special Topic Conference on Microtechnologies in Medecine&Biology, 2002, United States. pp 160 - 163, ⟨10.1109/MMB.2002.1002305⟩. ⟨hal-00986450⟩
  • Fabrice Morin, Matthieu Denoual, Laurent Griscom, Bruno Le Pioufle, Hiroyuki Fujita, et al.. Controlling Cell Development by Microfluidic Techniques : a Step towards Whole-Cell Biosensors with Defined Biological Features. 6th Micro Total Analysis System (uTAS), 2002, Japan. pp.10.1007. ⟨hal-00986459⟩
  • Gonzalo Cabodevila, Marie Frénéa, Agnes Tixier, Katel Cozic, Bruno Le Pioufle, et al.. Arrayed Micro Needles and Electrodes for Aligned Cell Capture and Gene Insertion. Chemicro, Mar 2002, Kyoto, Japan. ⟨hal-00107155⟩
  • Gonzalo Cabodevila, Hiroyuki Fujita, Bruno Le Pioufle. Arrayed Micro Needles for Mechanical Gene Insertion. Proceedings of SPIE -- Volume 4937 Biomedical Applications of Micro- and Nanoengineering,, Nov 2002, Melbourne, Australia. pp.90-97, ⟨10.1117/12.473962⟩. ⟨hal-00107288⟩
  • G. Cabodevila, Bruno Le Pioufle, H. Fujita. Arrayed micro needles for mechanical gene insertion. Biomedical Applications of Micro- and Nanoengineering, 2002, Australia. pp.90-97. ⟨hal-00795248⟩
  • M. Frenea, Hervé Lhermite, Bruno Le Pioufle, H. Fujita. Design of biochip microelectrode arrays for cell arrangement. 2nd Annual International Ieee-Embs Special Topic Conference on Microtechnologies in Medicine & Biology, Proceedings, 2002, United States. pp.140-143, ⟨10.1109/mmb.2002.1002281⟩. ⟨hal-00795221⟩
  • L. Griscom, P. Degenaar, Bruno Le Pioufle, E. Tamiya, H. Fujita. Soft lithographic techniques for guidance of hippocampal neurons on micro-electrode arrays. Transducers '01: Eurosensors Xv, Digest of Technical Papers, Vols 1 and 2, 2001, Germany. pp.338-341. ⟨hal-00795227⟩
  • A. Tixier, L. Griscom, K. Cozic, H. Nagai, Bruno Le Pioufle, et al.. Catching and attaching cells using an array of microholes. 1st Annual International Ieee-Embs Special Topic Conference on Microtechnologies in Medicine & Biology, Proceedings, 2000, France. pp.36-40, ⟨10.1109/mmb.2000.893736⟩. ⟨hal-00795228⟩
  • Sandrine Hallaert, Emmanuel Sarraute, Bruno Le Pioufle. Numerical and Analytical Modeling of the Piezoelectric Transformer and Experimental Verification. Nanotech, 1999, France. pp.198-201. ⟨hal-00794999⟩