Bruno Le Pioufle

**Bruno LE PIOUFLE, Professor at the Ecole Normale Supérieure Paris-Saclay** ================================================================================ *E.N.S. Paris-Saclay, 4 av. des sciences, 91190 Gif-sur-Yvette, France,* *Phone: 001 33 1 81875560, email: [send an email](https://hebergement.universite-paris-saclay.fr/biomis_d/?page_id=190)* **EDUCATION:** 1997: Accreditation to supervise research , University of PARIS 11 1991: French Ph.D., University of PARIS 11 **PROFESSIONAL EXPERIENCE:** Since 2020: Director of Institut d'Alembert (CNRS FR 3242, University Paris-Saclay) since 2007: Professor at ENS Cachan, (now ENS Paris-Saclay) 2005-2007: Director of LIMMS/CNRS IIS,UMI 2820, University of Tokyo, group of S. Takeuchi 1999: Professor à l’ENS de Cachan, Creation and Direction of BIOMIS group(1999-2005) 1997-1999: CNRS researcher at LIMMS, University of Tokyo, IIS, group of H. Fujita 1992-1997: Associate professor ar ENS Cachan **MAIN RESEARCH ACTIVITIES** B. Le Pioufle have been working since 1997 on the conception of bio-medical purpose microsystems. His main scientific concerns are 1) the conception of microfluidic biochips integrating biological or solid-state nanopores for the biosensing and 2) cell biochips. He spent 4 years at University of Tokyo, in the groups of H. Fujita, then in the group of S. Takeuchi. He was Director of LIMMS (International laboratory between CNRS and University of Tokyo). He worked in collaboration with S. Takeuchi on the conception of parallelized biochips for the screening on transmembrane molecules. He is also working on biochips for the cell analysis and treatment, and organ on chip. He is working on cell handling on a chip using dielectrophoresis, cell electroporation on a chip, microfluidics, surface functionalization of biochips.

**Bruno LE PIOUFLE, Professor at the Ecole Normale Supérieure Paris-Saclay** ================================================================================ *E.N.S. Paris-Saclay, 4 av. des sciences, 91190 Gif-sur-Yvette, France,* *Phone: 001 33 1 81875560, email: bruno.le-pioufle@ens-paris-saclay.fr* **EDUCATION:** 1997: Accreditation to supervise research , University of PARIS 11 1991: French Ph.D., University of PARIS 11 **PROFESSIONAL EXPERIENCE:** Since 2020: Director of [Institut d'Alembert](http://ida.ens-paris-saclay.fr/version-anglaise/ "Institut d'Alembert") (CNRS FR 3242, University Paris-Saclay) since 2007: Professor at ENS Cachan, (now ENS Paris-Saclay) 2005-2007: Director of LIMMS/CNRS IIS,UMI 2820, University of Tokyo, group of S. Takeuchi 1999: Professor à l’ENS de Cachan, Creation and Direction of BIOMIS group(1999-2005) 1997-1999: CNRS researcher at LIMMS, University of Tokyo, IIS, group of H. Fujita 1992-1997: Associate professor ar ENS Cachan **MAIN RESEARCH ACTIVITIES** B. Le Pioufle have been working since 1997 on the conception of bio-medical purpose microsystems. His main scientific concerns are 1) the conception of microfluidic biochips for the monitoring of membrane proteins and ion channels and 2) cell biochips. He spent 4 years at University of Tokyo, in the groups of H. Fujita, then in the group of S. Takeuchi. He was Director of LIMMS (International laboratory between CNRS and University of Tokyo). He worked in collaboration with S. Takeuchi on the conception of parallelized biochips for the screening on transmembrane molecules. He is also working on biochips for the cell analysis and treatment, and organ on chip. He is working on cell handling on a chip using dielectrophoresis, cell electroporation on a chip, microfluidics, surface functionalization of biochips. The main projects on which he has been working are 1) the study and conception of highly parallelized cell biochips for analysis (high throughput screening) or treatment (gene transfection on a chip) 2) the study and conception of biochips for ex-vivo (on a chip) analysis of physiological models 3) the design of biochips designed for the delivery of high amplitude electrical nanosecond pulses for the treatment of cells.