Alkylated flavanones from the bark of Cryptocarya chartacea as dengue virus NS5 polymerase inhibitors.
Pierre-Marie Allard
,
Elise Tran Huu Dau
,
Cécilia Eydoux
,
Jean-Claude Guillemot
,
Vincent Dumontet
,
et al.
Article dans une revue
hal-00684627v1
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Crystal structures ofLymphocytic choriomeningitis virusendonuclease domain complexed with diketo-acid ligands
Magali Saez-Ayala
,
Elsie Yekwa
,
Mauro Carcelli
,
Bruno Canard
,
Karine Alvarez
,
et al.
Article dans une revue
hal-03078366v1
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In Vitro Suppression of K65R Reverse Transcriptase-Mediated Tenofovir- and Adefovir-5'-Diphosphate Resistance Conferred by the Boranophosphonate Derivatives
A. Frangeul
,
Karine Barral
,
K. Alvarez
,
B. Canard
Article dans une revue
hal-02061675v1
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Substrate selectivity of Dengue and Zika virus NS5 polymerase towards 2′-modified nucleotide analogues
Supanee Potisopon
,
Francois Ferron
,
Véronique Fattorini
,
Barbara Selisko
,
Bruno Canard
Article dans une revue
hal-01802946v1
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SPINE bioinformatics and data-management aspects of high-throughput structural biology.
S. Albeck
,
Pedro Maria Alzari
,
C. Andreini
,
L. Banci
,
I. M. Berry
,
et al.
Article dans une revue
hal-00187834v1
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The viral capping enzyme nsP1: a novel target for the inhibition of chikungunya virus infection
L. Delang
,
C. Li
,
A. Tas
,
G. Querat
,
I. C. Albulescu
,
et al.
Article dans une revue
hal-01439113v1
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Gln151 of HIV-1 reverse transcriptase acts as a steric gate towards clinically relevant acyclic phosphonate nucleotide analogues.
Antoine Frangeul
,
Cécile Bussetta
,
Jérôme Deval
,
Karine Barral
,
Karine Alvarez
,
et al.
Antiviral Therapy , 2019, 13 (1), pp.115-24
Article dans une revue
hal-02061712v1
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Synthesis and Anti-BVDV Activity of Acridones As New Potential Antiviral Agents 1
Oriana Tabarrini
,
Giuseppe Manfroni
,
Arnaldo Fravolini
,
Violetta Cecchetti
,
Stefano Sabatini
,
et al.
Article dans une revue
istex
hal-02459231v1
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Structural Analysis of the Activation of Ribavirin Analogs by NDP Kinase: Comparison with Other Ribavirin Targets
Sarah Gallois-Montbrun
,
Yuxing Chen
,
Hélène Dutartre
,
Magali Sophys
,
Solange Moréra
,
et al.
Article dans une revue
hal-02459258v1
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Biodiversity as a source of potent and selective inhibitors of Chikungunya virus replication
Pieter Leyssen
,
Jacqueline Smadja
,
Philippe Rasoanaivo
,
Ameenah Gurib-Fakim
,
Mohamad Fawzi-Mahomoodally
,
et al.
Gurib-Fakim, A.
Novel Plant Bioresources, Applications in Food, Medicine and Cosmetics, , John Wiley & Sons, Ltd, Chichester UK., pp.151-160, 2014, 978-1-118-46061-0.
⟨10.1002/9781118460566.ch11⟩
Chapitre d'ouvrage
hal-01163238v1
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The Imidazopyrrolopyridine Analogue AG110 Is a Novel, Highly Selective Inhibitor of Pestiviruses That Targets the Viral RNA-Dependent RNA Polymerase at a Hot Spot for Inhibition of Viral Replication
Jan Paeshuyse
,
Jean-Michel Chezal
,
Matheus Froeyen
,
Pieter Leyssen
,
Hélène Dutartre
,
et al.
Article dans une revue
hal-02459217v1
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Protein-primed RNA synthesis in SARS-CoVs and structural basis for inhibition by AT-527
Ashleigh Shannon
,
Véronique Fattorini
,
Bhawna Sama
,
Barbara Selisko
,
Mikael Feracci
,
et al.
2023
Pré-publication, Document de travail
hal-04061889v1
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A Relaxed Discrimination of 2′- O -Methyl-GTP Relative to GTP between de Novo and Elongative RNA Synthesis by the Hepatitis C RNA-dependent RNA Polymerase NS5B
Hélène Dutartre
,
Joëlle Boretto
,
Jean Claude Guillemot
,
Bruno Canard
Article dans une revue
hal-02459254v1
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First insights into the structural features of Ebola virus methyltransferase activities
Coralie Valle
,
Baptiste Martin
,
François Ferron
,
Véronique Roig-Zamboni
,
Aline Desmyter
,
et al.
Article dans une revue
hal-03334409v1
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The C-Terminal Domain of the Sudan Ebolavirus L Protein Is Essential for RNA Binding and Methylation
Coralie Valle
,
Baptiste Martin
,
Françoise Debart
,
Jean-Jacques Vasseur
,
Isabelle Imbert
,
et al.
Article dans une revue
hal-02890587v1
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Phylogenetic analysis of the pathogenic anaerobe Clostridium perfringens using the 16S rRNA nucleotide sequence.
Bruno Canard
,
Thierry Garnier
,
Bénédicte Lafay
,
Richard Christen
,
Stewart T. Cole
Article dans une revue
hal-00412941v1
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Design, Synthesis and Discovery of N,N’ ‐Carbazoyl‐aryl‐urea Inhibitors of Zika NS5 Methyltransferase and Virus Replication
Sharon Spizzichino
,
Giulio Mattedi
,
Kate Lauder
,
Coralie Valle
,
Wahiba Aouadi
,
et al.
Article dans une revue
hal-02890596v1
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Synthesis, Structure–Activity Relationships, and Antiviral Profiling of 1-Heteroaryl-2-Alkoxyphenyl Analogs As Inhibitors of SARS-CoV-2 Replication
Dorothée Bardiot
,
Laura Vangeel
,
Mohamed Koukni
,
Philippe Arzel
,
Marleen Zwaagstra
,
et al.
Article dans une revue
hal-03561598v1
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A Novel, Highly Selective Inhibitor of Pestivirus Replication That Targets the Viral RNA-Dependent RNA Polymerase
Jan Paeshuyse
,
Pieter Leyssen
,
Eric Mabery
,
Nina Boddeker
,
Robert Vrancken
,
et al.
Article dans une revue
hal-02459234v1
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High-yield production of short GppA- and 7Me GppA-capped RNAs and HPLC-monitoring of methyltransfer reactions at the guanine-N7 and adenosine-2'O positions.
F. Peyrane
,
B. Selisko
,
Etienne Decroly
,
J.-J. Vasseur
,
D. Benarroch
,
et al.
Nucleic Acids Research , 2007, 35, pp.1-11
Article dans une revue
hal-00346549v1
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A Versatile Class of 1,4,4-Trisubstituted Piperidines Block Coronavirus Replication In Vitro
Sonia de Castro
,
Annelies Stevaert
,
Miguel Maldonado
,
Adrien Delpal
,
Julie Vandeput
,
et al.
Article dans une revue
hal-03937322v1
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Dengue Virus NS5 Transcribes Metabolite-Capped, RIG-I Sensitive vRNAs
Brandon Schweibenz
,
Mihai Solotchi
,
Etienne Decroly
,
Barbara Selisko
,
Bruno Canard
,
et al.
Article dans une revue
hal-03426114v1
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Structure-function analysis of the nsp14 N7-guanine methyltransferase reveals an essential role in Betacoronavirus replication
Natacha S Ogando
,
Priscila El Kazzi
,
Clara C Posthuma
,
Volker Thiel
,
Bruno Canard
,
et al.
2021
Pré-publication, Document de travail
hal-03426119v1
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A61 Large RNA genomes: Is RNA polymerase fidelity enough?
F. Ferron
,
B. Canard
Article dans une revue
hal-02613419v1
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Application of the use of high-throughput technologies to the determination of protein structures of bacterial and viral pathogens
M. J. Fogg
,
P. Alzari
,
M. Bahar
,
I. Bertini
,
J.-M. Betton
,
et al.
Article dans une revue
pasteur-03139239v1
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Zika Virus Methyltransferase: Structure and Functions for Drug Design Perspectives
Bruno Coutard
,
Karine Barral
,
Julie Lichiere
,
Barbara Selisko
,
Baptiste Martin
,
et al.
Article dans une revue
hal-01802793v1
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PHYTOCHIK: Biodiversity As A Source of Selective Inhibitors of CHIKV Replication
Pieter Leyssen
,
Marc Litaudon
,
Jean-Claude Guillemot
,
Philippe Rasoanaivo
,
Jacqueline Smadja
,
et al.
Article dans une revue
istex
hal-01187697v1
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Arenaviridae exoribonuclease presents genomic RNA edition capacity.
Elsie Laban Yekwa
,
Chutima Aphibanthammakit
,
Xavier Carnec
,
Caroline Picard
,
Bruno Canard
,
et al.
2019
Pré-publication, Document de travail
hal-02361017v1
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A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase
Ashleigh Shannon
,
Véronique Fattorini
,
Bhawna Sama
,
Barbara Selisko
,
Mikael Feracci
,
et al.
Article dans une revue
hal-03572811v1
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The enzymes for genome size increase and maintenance of large (+)RNA viruses
Francois Ferron
,
Bhawna Sama
,
Etienne Decroly
,
Bruno Canard
Article dans une revue
hal-03345450v1
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