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Investigating the mode of action of the redox-active antimalarial drug plasmodione using the yeast model

 Pierre Mounkoro , Thomas Michel , Stéphanie Blandin , Marie-Pierre Golinelli-Cohen , Elisabeth Davioud-Charvet , et al.
Free Radical Biology and Medicine, 2019, 141, pp.269-278. ⟨10.1016/j.freeradbiomed.2019.06.026⟩
Article dans une revue hal-02170571v1

HDQ, a Potent Inhibitor of Plasmodium falciparum Proliferation, Binds to the Quinone Reduction Site of the Cytochrome bc 1 Complex

 Cindy Vallières , Nicholas Fisher , Thomas Antoine , Mohammed Al-Helal , Paul Stocks , et al.
Antimicrobial Agents and Chemotherapy, 2012, 56 (7), pp.3739-3747. ⟨10.1128/AAC.00486-12⟩
Article dans une revue hal-03470770v1

Human Mitochondrial Cytochrome b Variants Studied in Yeast: Not All Are Silent Polymorphisms

 Zehua Song , Anaïs Laleve , Cindy Vallières , John E. Mcgeehan , Rhiannon E. Lloyd , et al.
Human Mutation, 2016, 37 (9), pp.933--941. ⟨10.1002/humu.23024⟩
Article dans une revue hal-02394420v1
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Proton-transfer pathways in the mitochondrial S. cerevisiae cytochrome c oxidase

 Markus L. Björck , Jóhanna Vilhjálmsdóttir , Andrew M. Hartley , Brigitte Meunier , Linda Näsvik Öjemyr , et al.
Scientific Reports, 2019, 9 (1), pp.20207. ⟨10.1038/s41598-019-56648-9⟩
Article dans une revue hal-02431238v1

Transcriptional response to nitrosative stress in Saccharomyces cerevisiae.

 Susannah Horan , Ingrid Bourges , Brigitte Meunier
Yeast, 2006, 23 (7), pp.519-35. ⟨10.1002/yea.1372⟩
Article dans une revue hal-00133447v1

Is cytochrome b glutamic acid 272 a quinol binding residue in the bc1 complex of Saccharomyces cerevisiae?

 Nadir Seddiki , Brigitte Meunier , Danielle Lemesle-Meunier , Gaël Brasseur
Biochemistry, 2008, 47 (8), pp.2357-68. ⟨10.1021/bi701905a⟩
Article dans une revue istex hal-00473793v1
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The TKFC Ala185Thr variant, reported as ‘null’ for fructose metabolism, is fully active as triokinase

 João M Ribeiro , María Jesús Costas , Alicia Cabezas , Brigitte Meunier , Alexandros Onoufriadis , et al.
FEBS Letters, 2022, ⟨10.1002/1873-3468.14309⟩
Article dans une revue hal-03564461v1

Production of transmitochondrial cybrids containing naturally occurring pathogenic mtDNA variants.

 Deborah Pye , Dimitra S Kyriakouli , Geoffrey A Taylor , Riem Johnson , Matthias Elstner , et al.
Nucleic Acids Research, 2006, 34 (13), pp.e95. ⟨10.1093/nar/gkl516⟩
Article dans une revue hal-00168043v1
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Directed evolution predicts cytochrome b G37V target site modification as probable adaptive mechanism towards the QiI fungicide fenpicoxamid in Zymoseptoria tritici

 Guillaume Fouché , Thomas Michel , Anaïs Lalève , Nick Wang , David Young , et al.
Environmental Microbiology, 2021, 24 (03), pp.1117-1132. ⟨10.1111/1462-2920.15760⟩
Article dans une revue hal-03357067v1

Correction for Khalimonchuk et al., "Formation of the Redox Cofactor Centers during Cox1 Maturation in Yeast Cytochrome Oxidase

 Oleh Khalimonchuk , Megan Bestwick , Brigitte Meunier , Talina C. Watts , Dennis R. Winge
Molecular and Cellular Biology, 2017, 37 (11), ⟨10.1128/MCB.00127-17⟩
Article dans une revue hal-02389776v1
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Revisiting the mode of action of the antimalarial proguanil using the yeast model

 Pierre Mounkoro , Thomas Michel , Brigitte Meunier
Biochemical and Biophysical Research Communications, 2021, 534, pp.94-98. ⟨10.1016/j.bbrc.2020.12.004⟩
Article dans une revue hal-03054347v1

Additive effect of nuclear and mitochondrial mutations in a patient with mitochondrial encephalomyopathy

 Claudia Nesti , Maria Chiara Meschini , Brigitte Meunier , Michele Sacchini , Stefano Doccini , et al.
Human Molecular Genetics, 2015, 24 (11), pp.3248--3256. ⟨10.1093/hmg/ddv078⟩
Article dans une revue hal-01452058v1
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Mitochondrial complex III Qi -site inhibitor resistance mutations found in laboratory selected mutants and field isolates

 Pierre Mounkoro , Thomas Michel , Rafik Benhachemi , Georgiana Surpateanu , Bogdan I. Iorga , et al.
Pest Management Science, 2019, 75 (8), pp.2107-2114. ⟨10.1002/ps.5264⟩
Article dans une revue hal-02182323v1

A rapid in vivo colorimetric library screen for inhibitors of microbial respiration.

 Cindy Vallières , Nicholas Fisher , Marc Lemoine , Olivier Pamlard , Sandra Beaupierre , et al.
ACS Chemical Biology, 2012, 7 (10), pp.1659-65. ⟨10.1021/cb3002717⟩
Article dans une revue hal-00749494v1

Identification and functional prediction of mitochondrial complex III and IV mutations associated with glioblastoma

 R. E. Lloyd , K. Keatley , D. T. J. Littlewood , Brigitte Meunier , W. V. Holt , et al.
Neuro-Oncology, 2015, 17 (7), pp.942--952. ⟨10.1093/neuonc/nov020⟩
Article dans une revue hal-02397513v1
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Interaction of picolinamide fungicide primary metabolites UK‐2A and CAS ‐649 with the cytochrome bc 1 complex Qi site: mutation effects and modeling in Saccharomyces cerevisiae

 David Young , Nick Wang , Brigitte Meunier
Pest Management Science, In press, ⟨10.1002/ps.6893⟩
Article dans une revue hal-03643114v1
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Bi-allelic Variants in TKFC Encoding Triokinase/FMN Cyclase Are Associated with Cataracts and Multisystem Disease

 Saskia B. Wortmann , Brigitte Meunier , Lamia Mestek-Boukhibar , Florence van Den Broek , Elaina M. Maldonado , et al.
American Journal of Human Genetics, 2020, 106, pp.256 - 263. ⟨10.1016/j.ajhg.2020.01.005⟩
Article dans une revue hal-02464288v1
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A role for the succinate dehydrogenase in the mode of action of the redox-active antimalarial drug, plasmodione

 Pierre Mounkoro , Thomas Michel , Marie-Pierre Golinelli-Cohen , Stephanie Blandin , Elisabeth Davioud-Charvet , et al.
Free Radical Biology and Medicine, 2021, ⟨10.1016/j.freeradbiomed.2020.11.010⟩
Article dans une revue hal-03026255v1
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Study of Metyltetraprole, an unusual agrofungicide targeting the Q o -site of cytochrome bc 1 complex

 Claudia Serot , Thomas Michel , Valentine Lucas , Brigitte Meunier
2022
Pré-publication, Document de travail hal-03582522v1

Structure of yeast cytochrome c oxidase in a supercomplex with cytochrome bc1

 Andrew M. Hartley , Natalya Lukoyanova , Yunyi Zhang , Alfredo Cabrera-Orefice , Susanne Arnold , et al.
Nature Structural and Molecular Biology, 2019, 26 (1), pp.78--83. ⟨10.1038/s41594-018-0172-z⟩
Article dans une revue hal-02171150v1

Interplay between the hinge region of iron sulphur protein and the Qo site in the bc1 complex — Analysis of Plasmodium-like mutations in the yeast enzyme

 Zehua Song , Jérôme Clain , Bogdan I. Iorga , Cindy Vallières , Anaïs Lalève , et al.
Biochimica biophysica acta (BBA) - Bioenergetics, 2015, 1847 (12), pp.1487 - 1494. ⟨10.1016/j.bbabio.2015.08.005⟩
Article dans une revue hal-01402828v1

Saccharomyces cerevisiae-based mutational analysis of the bc1 complex Qo site residue 279 to study the trade-off between atovaquone resistance and function

 Zehua Song , Jérôme Clain , Bogdan I. Iorga , Zhou Yi , Nicholas Fisher , et al.
Antimicrobial Agents and Chemotherapy, 2015, 59 (7), pp.4053--4058. ⟨10.1128/AAC.00710-15⟩
Article dans une revue hal-02400327v1

The H channel is not a proton transfer path in yeast cytochrome c oxidase

 Aapo Malkamäki , Brigitte Meunier , Marco Reidelbach , Peter R. Rich , Vivek Sharma
Biochimica biophysica acta (BBA) - Bioenergetics, 2019, 1860 (9), pp.717--723. ⟨10.1016/j.bbabio.2019.07.012⟩
Article dans une revue hal-02323288v1

Integrated Approach Reveals Role of Mitochondrial Germ-Line Mutation F18L in Respiratory Chain, Oxidative Alterations, Drug Sensitivity, and Patient Prognosis in Glioblastoma

 Kathleen Keatley , Samuel Stromei-Cleroux , Tammy Wiltshire , Nina Rajala , Gary Burton , et al.
International Journal of Molecular Sciences, 2019, 20 (13), ⟨10.3390/ijms20133364⟩
Article dans une revue hal-02323290v1
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Rcf2 revealed in cryo-EM structures of hypoxic isoforms of mature mitochondrial III-IV supercomplexes

 Andrew M. Hartley , Brigitte Meunier , Nikos Pinotsis , Amandine Maréchal
Proceedings of the National Academy of Sciences of the United States of America, 2020, ⟨10.1073/pnas.1920612117⟩
Article dans une revue hal-02547878v1

Human COQ9 Rescues a coq9 Yeast Mutant by Enhancing Coenzyme Q Biosynthesis from 4-Hydroxybenzoic Acid and Stabilizing the CoQ-Synthome

 Cuiwen H. He , Dylan S. Black , Christopher M. Allan , Brigitte Meunier , Shamima Rahman , et al.
Frontiers in Physiology, 2017, 8, pp.463. ⟨10.3389/fphys.2017.00463⟩
Article dans une revue hal-02281953v1
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Mutational analysis of the Qi-site proton pathway in yeast cytochrome bc1 complex

 Zehua Song , Yangfeng Hu , Bogdan I. Iorga , Cindy Vallières , Nicholas Fisher , et al.
Biochemical and Biophysical Research Communications, 2020, 523 (3), pp.615-619. ⟨10.1016/j.bbrc.2019.12.102⟩
Article dans une revue hal-02445554v1
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Design, synthesis, and biological evaluation of multiple targeting antimalarials

 Yiqing Yang , Tongke Tang , Xiaolu Li , Thomas Michel , Liqin Ling , et al.
Acta Pharmaceutica Sinica B, 2021, ⟨10.1016/j.apsb.2021.05.008⟩
Article dans une revue hal-03261571v1
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Assessing the risk of resistance selection towards Qil fungicides in Zymoseptoria tritici

 Guillaume Fouche , Anne-Sophie Walker , Sabine, Helma S. H. Fillinger-David , Brigitte Meunier , David Young
Journées Jean Chevauchon JJC2018 - 12èmes Rencontres de Phytopathologie & Mycologie,, Jan 2018, Aussois, France. , p.65, 2018
Poster de conférence hal-02787513v1

Caspase-8 sumoylation is associated with nuclear localization.

 Laurence Besnault-Mascard , Corinne Leprince , Marie Thérèse Auffredou , Brigitte Meunier , Marie Françoise Bourgeade , et al.
Oncogene, 2005, 24 (20), pp.3268-73. ⟨10.1038/sj.onc.1208448⟩
Article dans une revue hal-00320527v1
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