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Genetic investigation of purine nucleotide imbalance in Saccharomyces cerevisiae

Christelle Saint-Marc , Johanna Ceschin , Claire Almyre , Benoît Pinson , Bertrand Daignan-Fornier
Current Genetics, 2020, 66 (6), pp.1163-1177. ⟨10.1007/s00294-020-01101-y⟩
Article dans une revue hal-02989028v1
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Genetic investigation of purine nucleotide imbalance in Saccharomyces cerevisiae

Christelle Saint-Marc , Johanna Ceschin , Benoît Pinson , Claire Almyre , Bertrand Daignan-Fornier
Current Genetics, 2020, 66 (6), pp.1163-1177. ⟨10.1007/s00294-020-01101-y⟩
Article dans une revue hal-03379696v1

Yeast Ppz1 protein phosphatase toxicity involves the alteration of multiple cellular targets

Christelle Saint-Marc , Johanna Ceschin , Claire Almyre , Benoît Pinson , Bertrand Daignan-Fornier , et al.
Scientific Reports, 2020, 10 (1), pp.15613. ⟨10.1038/s41598-020-72391-y⟩
Article dans une revue hal-02992958v1
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Yeast Ppz1 protein phosphatase toxicity involves the alteration of multiple cellular targets

Bertrand Daignan-Fornier
Scientific Reports, In press, ⟨10.1038/s41598-020-72391-y⟩
Article dans une revue hal-02992849v1

Sub-families of α/β Barrel Enzymes: A New Adenine Deaminase Family

Carin Ribard , Michel Rochet , Bernard Labedan , Bertrand Daignan-Fornier , Pedro Alzari , et al.
Journal of Molecular Biology, 2003, 334 (5), pp.1117-1131. ⟨10.1016/j.jmb.2003.10.005⟩
Article dans une revue istex pasteur-03144607v1
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Structural Insights into the Forward and Reverse Enzymatic Reactions in Human Adenine Phosphoribosyltransferase

Jessica Huyet , Mohammad Ozeir , Marie-Claude Burgevin , Anne Olivier-Bandini , Franck Auge , et al.
Cell Chemical Biology, 2018, 25 (6), pp.666-676.e4. ⟨10.1016/j.chembiol.2018.02.011⟩
Article dans une revue hal-02346886v1
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Tye7 regulates yeast Ty1 retrotransposon sense and antisense transcription in response to adenylic nucleotides stress

Geraldine Servant , Benoît Pinson , Aurélie Tchalikian-Cosson , Fanny Coulpier , Sophie Lemoine , et al.
Nucleic Acids Research, 2012, 40 (12), pp.5271-5282. ⟨10.1093/nar/gks166⟩
Article dans une revue hal-02119179v1
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Disruption of Nucleotide Homeostasis by the Antiproliferative Drug 5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside Monophosphate (AICAR)

Johanna Ceschin , Hans Caspar Hürlimann , Christelle Saint-Marc , Delphine Albrecht , Typhaine Violo , et al.
Journal of Biological Chemistry, 2015, 290 (39), pp.23947-23959. ⟨10.1074/jbc.M115.656017⟩
Article dans une revue hal-02354937v1
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Purine Biosynthesis Pathways Are Required for Myogenesis in Xenopus laevis

Maëlle Duperray , Fanny Hardet , Elodie Henriet , Christelle Saint-Marc , Eric Boué-Grabot , et al.
Cells, 2023, 12 (19), pp.2379. ⟨10.3390/cells12192379⟩
Article dans une revue hal-04225134v1

Yeast Ppz1 protein phosphatase toxicity involves the alteration of multiple cellular targets

Diego Velázquez , Marcel Albacar , Chunyi Zhang , Carlos Calafí , María López-Malo , et al.
Scientific Reports, 2020, 10 (1), ⟨10.1038/s41598-020-72391-y⟩
Article dans une revue hal-02989026v1
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Purine Homeostasis Is Necessary for Developmental Timing, Germline Maintenance and Muscle Integrity in Caenorhabditis elegans

Roxane Marsac , Benoit Pinson , Christelle Saint-Marc , María Olmedo , Marta Artal-Sanz , et al.
Genetics, 2019, 211 (4), pp.1297-1313. ⟨10.1534/genetics.118.301062⟩
Article dans une revue hal-02346559v1
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Multiple chemo-genetic interactions between a toxic metabolite and the ubiquitin pathway in yeast

Delphine Albrecht , Hans C Hürlimann , Johanna Ceschin , Christelle Saint-Marc , Benoît Pinson , et al.
Current Genetics, 2018, 64 (6), pp.1275-1286. ⟨10.1007/s00294-018-0843-7⟩
Article dans une revue hal-02346868v1
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Dual control of NAD + synthesis by purine metabolites in yeast

Benoit Pinson , Johanna Ceschin , Christelle Saint-Marc , Bertrand Daignan-Fornier
Article dans une revue hal-02346546v1

Structural basis for substrate selectivity and nucleophilic substitution mechanisms in human adenine phosphoribosyltransferase catalyzed reaction

Mohammad Ozeir , Jessica Huyet , Marie-Claude Burgevin , Benoît Pinson , Françoise Chesney , et al.
Journal of Biological Chemistry, 2019, ⟨10.1074/jbc.RA119.009087⟩
Article dans une revue hal-04347565v1
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Identification of Yeast and Human 5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAr) Transporters

Johanna Ceschin , Christelle Saint-Marc , Jean Laporte , Adrien Labriet , Chloe Philippe , et al.
Journal of Biological Chemistry, 2014, 289 (24), pp.16844-16854. ⟨10.1074/jbc.M114.551192⟩
Article dans une revue hal-02354940v1
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On demand utilization of phosphoribosyl pyrophosphate by downstream anabolic pathways

Benoît Pinson , Michel Moenner , Christelle Saint-Marc , Alexandra Granger-Farbos , Bertrand Daignan-Fornier
Journal of Biological Chemistry, In press, ⟨10.1016/j.jbc.2023.105011⟩
Article dans une revue hal-04151647v1
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Serine hydroxymethyltransferase: a key player connecting purine, folate and methionine metabolism in Saccharomyces cerevisiae

Christelle Saint-Marc , Hans C Hürlimann , Bertrand Daignan-Fornier , Benoît Pinson
Current Genetics, 2015, 61 (4), pp.633-640. ⟨10.1007/s00294-015-0489-7⟩
Article dans une revue hal-02354935v1

A pharmaco-epistasis strategy reveals a new cell size controlling pathway in yeast.

Fabien Moretto , Isabelle Sagot , Bertrand Daignan-Fornier , Benoît Pinson
Molecular Systems Biology, 2013, 9, pp.707. ⟨10.1038/msb.2013.60⟩
Article dans une revue hal-00905847v1

Structural basis for substrate selectivity and nucleophilic substitution mechanisms in human adenine phosphoribosyltransferase catalyzed reaction

Mohammad Ozeir , Jessica Huyet , Marie-Claude Burgevin , Benoît Pinson , Françoise Chesney , et al.
Journal of Biological Chemistry, 2019, ⟨10.1074/jbc.RA119.009087⟩
Article dans une revue hal-04347428v1
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Proteasome- and SCF-dependent degradation of yeast adenine deaminase upon transition from proliferation to quiescence requires a new F-box protein named Saf1p.

Stéphanie Escusa , Jurgi Camblong , Jean-Marc Galan , Benoît Pinson , Bertrand Daignan-Fornier
Molecular Microbiology, 2006, 60(4), pp.1014-25. ⟨10.1111/j.1365-2958.2006.05153.x⟩
Article dans une revue hal-00023448v1
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Yeast to Study Human Purine Metabolism Diseases

Bertrand Daignan-Fornier , Benoit Pinson
Cells, 2019, 8 (1), pp.67. ⟨10.3390/cells8010067⟩
Article dans une revue hal-02346566v1

Yeast Ppz1 protein phosphatase toxicity involves the alteration of multiple cellular targets

Diego Velázquez , Marcel Albacar , Chunyi Zhang , Carlos Calafí , María López-Malo , et al.
Scientific Reports, 2020, 10 (1), pp.15613. ⟨10.1038/s41598-020-72391-y⟩
Article dans une revue hal-02992986v1

Chemo-Genetic Interactions Between Histone Modification and the Antiproliferation Drug AICAR Are Conserved in Yeast and Humans

Delphine Albrecht , Johanna Ceschin , Jim Dompierre , Florian Gueniot , Benoit Pinson , et al.
Genetics, 2016, 204 (4), pp.1447-1460. ⟨10.1534/genetics.116.192518⟩
Article dans une revue hal-02354934v1
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Metabolomics and proteomics identify the toxic form and the associated cellular binding targets of the anti-proliferative drug AICAR

Delphine C Douillet , Benoit Pinson , Johanna Ceschin , Hans C Hürlimann , Christelle Saint-Marc , et al.
Journal of Biological Chemistry, 2019, 294 (3), pp.805-815. ⟨10.1074/jbc.RA118.004964⟩
Article dans une revue hal-02346549v1
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5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-Monophosphate (AICAR), a Highly Conserved Purine Intermediate with Multiple Effects

Bertrand Daignan-Fornier , Benoit Pinson
Metabolites, 2012, 2 (2), pp.292-302. ⟨10.3390/metabo2020292⟩
Article dans une revue hal-02354941v1
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Structural basis for substrate selectivity and nucleophilic substitution mechanisms in human adenine phosphoribosyltransferase catalyzed reaction

Mohammad Ozeir , Jessica Huyet , Marie-Claude Burgevin , Benoit Pinson , Françoise Chesney , et al.
Journal of Biological Chemistry, 2019, 294 (32), pp.11980-11991. ⟨10.1074/jbc.RA119.009087⟩
Article dans une revue hal-02346528v1
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New biomarkers for early diagnosis of Lesch-Nyhan disease revealed by metabolic analysis on a large cohort of patients

Irène Ceballos-Picot , Aurélia Le Dantec , Anaïs Brassier , Jean-Philippe Jais , Morgan Ledroit , et al.
Orphanet Journal of Rare Diseases, 2015, 10 (1), pp.7. ⟨10.1186/s13023-014-0219-0⟩
Article dans une revue hal-02354938v1
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AICAR Antiproliferative Properties Involve the AMPK-Independent Activation of the Tumor Suppressors LATS 1 and 2

Chloe Philippe , Benoît Pinson , Jim Dompierre , Véronique Pantesco , Benoit Viollet , et al.
Neoplasia, 2018, 20 (6), pp.555-562. ⟨10.1016/j.neo.2018.03.006⟩
Article dans une revue hal-02346897v1