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Bertrand Aigle

Journal articles41 documents

  • Virginia S Lioy, Jean-Noel Lorenzi, Soumaya Najah, Thibault Poinsignon, Herve Leh, et al.. Dynamics of the compartmentalized Streptomyces chromosome during metabolic differentiation. Nature Communications, Nature Publishing Group, 2021, 12, pp.5221. ⟨10.1038/s41467-021-25462-1⟩. ⟨hal-03128776v2⟩
  • Mohamed Chafik Bourkaib, Stéphane Delaunay, Xavier Framboisier, Laurence Hotel, Bertrand Aigle, et al.. N-acylation of L-amino acids in aqueous media: Evaluation of the catalytic performances of Streptomyces ambofaciens aminoacylases. Enzyme and Microbial Technology, Elsevier, 2020, 137, pp.109536. ⟨10.1016/j.enzmictec.2020.109536⟩. ⟨hal-02868736⟩
  • Milena Gonzalo, Aurélie Deveau, Bertrand Aigle. Inhibitions Dominate but Stimulations and Growth Rescues Are Not Rare Among Bacterial Isolates from Grains of Forest Soil. Microbial Ecology, Springer Verlag, 2020, 80 (4), pp.872-884. ⟨10.1007/s00248-020-01579-6⟩. ⟨hal-02935408⟩
  • Martine Paindorge, Virginie Lang, Virginie Libante, Pascal Reboul, Bertrand Aigle. Accompagnement dans l’apprentissage de l’argumentation par une équipe pluridisciplinaire : quels effets sur les acteurs?. Revue internationale de pédagogie de l’enseignement supérieur, Association internationale de pédagogie universitaire, 2020, 36 (2), ⟨10.4000/ripes.2717⟩. ⟨hal-03041936⟩
  • Cláudia M Vicente, Jean-Michel Girardet, Laurence Hôtel, Bertrand Aigle. Molecular Dynamics to Elucidate the DNA-Binding Activity of AlpZ, a Member of the Gamma-Butyrolactone Receptor Family in Streptomyces ambofaciens. Frontiers in Microbiology, Frontiers Media, 2020, 11, ⟨10.3389/fmicb.2020.01255⟩. ⟨hal-02935390⟩
  • Mabrouka Benhadj, Djamila Gacemi-Kirane, Maxime Toussaint, Laurence Hotel, Cyril Bontemps, et al.. Diversity and antimicrobial activities of Streptomyces isolates from Fetzara Lake, north eastern Algeria. Annales de Biologie Clinique, John Libbey Eurotext, 2018, 76 (1), pp.81-95. ⟨10.1684/abc.2017.1316⟩. ⟨hal-01844922⟩
  • Cláudia M Vicente, Annabelle Thibessard, Jean-Noël Lorenzi, Mabrouka Benhadj, Laurence Hotel, et al.. Comparative Genomics among Closely Related Streptomyces Strains Revealed Specialized Metabolite Biosynthetic Gene Cluster Diversity. Antibiotics, MDPI, 2018, 7 (4), pp.86. ⟨10.3390/antibiotics7040086⟩. ⟨hal-01887213⟩
  • Annabelle Thibessard, Cláudia M Vicente, Claire Bertrand, Bertrand Aigle, Pierre Leblond. Draft Whole-Genome Shotgun Sequence of Streptomyces sp. Strain ETH9427. Microbiology Resource Announcements, American Society for Microbiology, 2018, 7 (12), pp.e01197. ⟨10.1128/MRA.01197-18⟩. ⟨hal-01887322⟩
  • Léna Dettori, Florent Ferrari, Xavier Framboisier, Cédric Paris, Yann Guiavarc’h, et al.. An aminoacylase activity from Streptomyces ambofaciens catalyzes the acylation of lysine on α-position and peptides on N-terminal position. Engineering in Life Sciences, Wiley-VCH Verlag, 2018, 18 (8), pp.589-599. ⟨10.1002/elsc.201700173⟩. ⟨hal-01959650⟩
  • Mingxun Wang, Jeremy J. Carver, Vanessa V. Phelan, Laura M. Sanchez, Neha Garg, et al.. Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking. Nature Biotechnology, Nature Publishing Group, 2016, 34 (8), pp.828-837. ⟨10.1038/nbt.3597⟩. ⟨hal-01371824⟩
  • Aurélie Deveau, Harald Gross, Béatrice Palin, Samina Mehnaz, Max Schnepf, et al.. Role of secondary metabolites in the interaction between Pseudomonas fluorescensand soil microorganisms under iron-limited conditions. FEMS Microbiology Ecology, Wiley-Blackwell, 2016, 92 (8), pp.1-11. ⟨10.1093/femsec/fiw107⟩. ⟨hal-01490770⟩
  • Bin Wang, Jinwei Ren, Liyuan Li, Fang Fan, Guohui Pan, et al.. Kinamycin biosynthesis employs a conserved pair of oxidases for B-ring contraction. Chemical Communications, Royal Society of Chemistry, 2015, 51 (42), pp.8845 - 8848. ⟨10.1039/c5cc01986a⟩. ⟨hal-01475728⟩
  • Bin Wang, Fang Fan, Jinwei Ren, Guomin Ai, Bertrand Aigle, et al.. Identification of Alp1U and Lom6 as epoxy hydrolases and implications for kinamycin and lomaiviticin biosynthesis. Nature Communications, Nature Publishing Group, 2015, 6, pp.1-5. ⟨10.1038/ncomms8674⟩. ⟨hal-01475795⟩
  • Marnix H Medema, Renzo Kottmann, Yi Yilmaz, Matthew Cummings, John B Biggins, et al.. Minimum Information about a Biosynthetic Gene cluster.. Nature Chemical Biology, Nature Publishing Group, 2015, 11 (9), pp.625-31. ⟨10.1038/nchembio.1890⟩. ⟨hal-01430728⟩
  • Justine Galet, Aurélie Deveau, Laurence Hotel, Pascale Frey-Klett, Pierre Leblond, et al.. Pseudomonas fluorescens Pirates both Ferrioxamine and Ferricoelichelin Siderophores from Streptomyces ambofaciens.. Applied and Environmental Microbiology, American Society for Microbiology, 2015, 81 (9), pp.3132-3141. ⟨10.1128/AEM.03520-14⟩. ⟨hal-01269032⟩
  • Annabelle Thibessard, Drago Haas, Claude Gerbaud, Bertrand Aigle, Sylvie Lautru, et al.. Complete genome sequence of Streptomyces ambofaciens ATCC 23877, the spiramycin producer. Journal of Biotechnology, Elsevier, 2015, 214, pp.117-118. ⟨10.1016/j.jbiotec.2015.09.020⟩. ⟨hal-01258341⟩
  • Justine Galet, Aurélie Deveau, Laurence Hotel, Pierre Leblond, Pascale Frey-Klett, et al.. Gluconic acid-producing Pseudomonas sp. prevent γ-actinorhodin biosynthesis by Streptomyces coelicolor A3(2). Archives of Microbiology, Springer Verlag, 2014, 196 (9), pp.619-627. ⟨10.1007/s00203-014-1000-4⟩. ⟨hal-01268576⟩
  • Robert Bunet, Ramona Riclea, Luisa Laureti, Laurence Hotel, Cedric Paris, et al.. A Single Sfp-Type Phosphopantetheinyl Transferase Plays a Major Role in the Biosynthesis of PKS and NRPS Derived Metabolites in Streptomyces ambofaciens ATCC23877. PLoS ONE, Public Library of Science, 2014, 9 (1), pp.e87607. ⟨10.1371/journal.pone.0087607⟩. ⟨hal-01272916⟩
  • Lijiang Song, Luisa Laureti, Christophe Eric Corre, Pierre Leblond, Bertrand Aigle, et al.. Cytochrome P450-mediated hydroxylation is required for polyketide macrolactonization in stambomycin biosynthesis. Journal of Antibiotics, Nature Publishing Group: Open Access Hybrid Model Option B, 2014, 67 (1), pp.71 - 76. ⟨10.1038/ja.2013.119⟩. ⟨hal-01474997⟩
  • Bertrand Aigle, Sylvie Lautru, Dieter Spiteller, Jeroen S. Dickschat, Gregory L. Challis, et al.. Genome mining of Streptomyces ambofaciens. Journal of Industrial Microbiology and Biotechnology, Springer Verlag, 2014, 41 (2), pp.251 - 263. ⟨10.1007/s10295-013-1379-y⟩. ⟨hal-01475037⟩
  • Neelu Nawani, Bertrand Aigle, Abul Mandal, Manish Bodas, Sofiane Ghorbel, et al.. Actinomycetes: role in biotechnology and medicine. BioMed Research International , Hindawi Publishing Corporation, 2013, 2013, ⟨10.1155/2013/687190⟩. ⟨hal-02645473⟩
  • S. Song, L Laureti, P Gomez-Escribano, D Fox, V Yeo, et al.. Bacterial genome mining for novel natural product discovery. Planta Medica, Georg Thieme Verlag, 2012, 78 (11), ⟨10.1055/s-0032-1320194⟩. ⟨hal-01667347⟩
  • Luisa Laureti, Lijiang Song, Sheng Huang, Christophe Corre, Pierre Leblond, et al.. Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens. Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 2011, 108 (15), pp.6258 - 6263. ⟨10.1073/pnas.1019077108⟩. ⟨hal-02651598⟩
  • R. Bunet, L. Song, M. Vaz Mendez, C. Corre, L. Hotel, et al.. Characterization and manipulation of the pathway-specific late regulator AlpW reveals Streptomyces ambofaciens as a new producer of kinamycins. Journal of Bacteriology, American Society for Microbiology, 2011, 193 ((5)), pp. 1142-1153. ⟨10.1128/JB.01269-10⟩. ⟨hal-00606766⟩
  • Samiha Sioud, Bertrand Aigle, Ines Karray-Rebai, Slim Smaoui, Samir Bejar, et al.. Integrative Gene Cloning and Expression System for Streptomyces sp. US 24 and Streptomyces sp. TN 58 Bioactive Molecule Producing Strains. Journal of Biomedicine and Biotechnology, Hindawi Publishing Corporation, 2009, 2009 (Article ID 464986), pp.464986. ⟨10.1155/2009/464986⟩. ⟨hal-01659292⟩
  • Catherine Eng, Charu Asthana, Bertrand Aigle, Sébastien Hergalant, Jean-Francois Mari, et al.. A new data mining approach for the detection of bacterial promoters combining stochastic and combinatorial methods. Journal of Computational Biology, Mary Ann Liebert, 2009, 16 (9), pp.1211-1225. ⟨10.1089/cmb.2008.0122⟩. ⟨inria-00419969⟩
  • Robert Bunet, M. V. Mendes, Nicolas Rouhier, Xiuhua Pang, L. Hotel, et al.. Regulation of the Synthesis of the Angucyclinone Antibiotic Alpomycin in Streptomyces ambofaciens by the Autoregulator Receptor AlpZ and Its Specific Ligand. Journal of Bacteriology, American Society for Microbiology, 2008, 190 (9), pp.3293 - 3305. ⟨10.1128/JB.01989-07⟩. ⟨hal-01659448⟩
  • Fabrice Touzain, Sophie Schbath, Isabelle Debled-Rennesson, Bertrand Aigle, Gregory Kucherov, et al.. SIGffRid: A tool to search for sigma factor binding sites in bacterial genomes using comparative approach and biologically driven statistics. BMC Bioinformatics, BioMed Central, 2008, 9 (73), pp.on line. ⟨10.1186/1471-2105-9-73⟩. ⟨inria-00580657⟩
  • Samiha Sioud, Ines Karray-Rebai, Hedi Aouissaoui, Bertrand Aigle, Samir Bejar, et al.. Targeted Gene Disruption of the Cyclo (L-Phe, L-Pro) Biosynthetic Pathway in Streptomyces sp. US24 Strain. Journal of Biomedicine and Biotechnology, Hindawi Publishing Corporation, 2007, 2007 (Art. No 91409), pp.1 - 9. ⟨10.1155/2007/91409⟩. ⟨hal-01659462⟩
  • Frédéric Choulet, Alexandre Gallois, B. Aigle, Sophie Mangenot, Claude Gerbaud, et al.. Intraspecific Variability of the Terminal Inverted Repeats of the Linear Chromosome of Streptomyces ambofaciens. Journal of Bacteriology, American Society for Microbiology, 2006, 188 (18), pp.6599 - 6610. ⟨10.1128/JB.00734-06⟩. ⟨hal-01659064⟩
  • Frédéric Choulet, Bertrand Aigle, Alexandre Gallois, Sophie Mangenot, Claude Gerbaud, et al.. Evolution of the terminal regions of the streptomyces linear chromosome. Molecular Biology and Evolution, Oxford University Press (OUP), 2006, 23 (12), pp.2361-2369. ⟨10.1093/molbev/msl108⟩. ⟨hal-02661267⟩
  • F. Choulet, A. Gallois, B. Aigle, S. Mangenot, C. Gerbaud, et al.. Intraspecific variability of the terminal regions of the Streptomyces ambofaciens. Journal of Bacteriology, American Society for Microbiology, 2006, 188, p 6599-6610. ⟨hal-00101141⟩
  • Bertrand Aigle, Xiuhua Pang, Bernard Decaris, Pierre Leblond. Involvement of AlpV, a New Member of the Streptomyces Antibiotic Regulatory Protein Family, in Regulation of the Duplicated Type II Polyketide Synthase alp Gene Cluster in Streptomyces ambofaciens. Journal of Bacteriology, American Society for Microbiology, 2005, 187 (7), pp.2491 - 2500. ⟨10.1128/JB.187.7.2491–2500.2005⟩. ⟨hal-01659049⟩
  • Virginie Roth, Bertrand Aigle, Robert Bunet, Thomas Wenner, Céline Fourrier, et al.. Differential and Cross-Transcriptional Control of Duplicated Genes Encoding Alternative Sigma Factors in Streptomyces ambofaciens. Journal of Bacteriology, American Society for Microbiology, 2004, 186 (16), pp.5355 - 5365. ⟨10.1128/JB.186.16.5355–5365.2004⟩. ⟨hal-01659043⟩
  • Xiuhua Pang, Bertrand Aigle, Jean-Michel Girardet, Sophie Mangenot, Jean-Luc Pernodet, et al.. Functional Angucycline-Like Antibiotic Gene Cluster in the Terminal Inverted Repeats of the Streptomyces ambofaciens Linear Chromosome. Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2004, 48 (2), pp.575 - 588. ⟨10.1128/AAC.48.2.575-588.2004⟩. ⟨hal-01659031⟩
  • Thomas Wenner, Virginie Roth, Gilles Fischer, Céline Fourrier, Bertrand Aigle, et al.. End-to-end fusion of linear deleted chromosomes initiates a cycle of genome instability in Streptomyces ambofaciens. Molecular Microbiology, Wiley, 2003, 50 (2), pp.411-425. ⟨10.1046/j.1365-2958.2003.03698.x⟩. ⟨hal-01659028⟩
  • B. Aigle, Anne Catherine Holl, Jaime F. Angulo, Pierre Leblond, Bernard Decaris. Characterization of two Streptomyces ambofaciens recA mutants: identification of the RecA protein by immunoblotting. FEMS Microbiology Letters, Wiley-Blackwell, 1997, 149, pp.181-7. ⟨10.1111/j.1574-6968.1997.tb10326.x⟩. ⟨hal-01658772⟩
  • T Umeyama, Y Tanabe, Bertrand Aigle, Y Horinouchi. Expression of the Streptomyces coelicolor A3(2) ptpA gene encoding a phosphotyrosine protein phosphatase leads to overproduction of secondary metabolites in S. lividans. FEMS Microbiology Letters, Wiley-Blackwell, 1996, 144 (2-3), pp.177-184. ⟨10.1016/0378-1097(96)00359-X⟩. ⟨hal-03205363⟩
  • Dominique Vandewiele, Jean-Nicolas Volff, Bertrand Aigle, Jean-Marc Simonet, Bernard Decaris. Isolation and characterization of a mutator strain of Streptomyces ambofaciens ATCC23877 exhibiting an increased level of genetic instability. Canadian Journal of Microbiology, NRC Research Press, 1996, 42 (6), pp.562 - 570. ⟨10.1139/m96-076⟩. ⟨hal-01659581⟩
  • B. Aigle, Dominique Schneider, Cécile Morilhat, Dominique Vandewiele, Anne Dary, et al.. An amplifiable and deletable locus of Streptomyces ambofaciens RP181110 contains a very large gene homologous to polyketide synthase genes. Microbiology, Microbiology Society, 1996, 142 (10), pp.2815 - 2824. ⟨10.1099/13500872-142-10-2815⟩. ⟨hal-01659577⟩
  • Dominique Schneider, Bertrand Aigle, Pierre Leblond, Jean-Marc Simonet, Bernard Decaris. Analysis of genome instability in Streptomyces ambofaciens. Journal of general microbiology, Society for General Microbiology, (Journal Sales), 1993, 139 (11), pp.2559-2567. ⟨10.1099/00221287-139-11-2559⟩. ⟨hal-01658593⟩

Conference papers12 documents

  • Drago Haas, Matthieu Barba, Cláudia Vincente, Géraldine Le Goff, Jamal Ouazzani, et al.. Searching For Specialized Metabolites Gene Clusters By Mining Genomic Islands: A New Comparative Genomics-Based Approach. International Symposium on the Biology of Actinomycetes, May 2017, Jeju, South Korea. ⟨hal-01655211⟩
  • Drago Haas, Matthieu Barba, Cláudia M Vicente, Amélie Garenaux, Sárka Nezbedová, et al.. Mining genomic islands with Synteruptor, a new strategy for identifying secondary metabolism gene clusters. The 13th International Symposium on the Genetics of Industrial Microorganisms, Oct 2016, Wuhan, China. ⟨hal-03042549⟩
  • Stephane Uroz, Marie-Pierre Turpault, Océane Nicolitch, Yannick Colin, Marc Buée, et al.. Impact of nutrient availability on the diversity, function and functioning of the forest soil bacterial communities: insights from the soil succession of the forest experimental site of Montiers.. Labex ARBRE conference, Oct 2016, Champenoux, France. ⟨hal-03339707⟩
  • Emmanuelle Jacquet, Bernard Gaume, Yves Gaillard, Eric Descourvières, Pascale Marange, et al.. Pédagogie renouvelée pour des cursus d'ingénierie à l'université. Colloque sur l'Enseignement des Technologies et des Sciences de l'Information et des Systèmes, CETSIS 2014, Oct 2014, Besançon, France. ⟨hal-01094950⟩
  • Sébastien Hergalant, Bertrand Aigle, Pierre Leblond, Jean-François Mari. Fouille de données du génome à l'aide de modèles de Markov cachés. Extraction et Gestion de Connaissances - EGC 2005, Jan 2005, Paris/France, France. pp.141 -- 148. ⟨inria-00001213⟩
  • Fabrice Touzain, Sophie Schbath, Isabelle Debled-Rennesson, Bertrand Aigle, Pierre Leblond, et al.. SIGffRid : Programme de recherche des sites de fixation des facteurs de transcription par approche comparative. Journées Ouvertes Biologie Informatique Mathématiques - JOBIM'05, Guy Perrière, Alain Guénoche et Christophe Geourjon, Jul 2005, Lyon, France. pp.417-425. ⟨inria-00000191⟩
  • Sébastien Hergalant, Bertrand Aigle, Bernard Decaris, Jean-François Mari, Pierre Leblond. Classification non supervisée par HMM de sites de fixation de facteurs de transcription chez les bactéries. 5èmes Journées Ouvertes : Biologie, Informatique et Mathématiques - JOBIM'04, 2004, Montréal, Canada, 1 p. ⟨inria-00107788⟩
  • Fabrice Touzain, Patricia Lavigne, Isabelle Debled-Rennesson, Bertrand Aigle, Pierre Leblond, et al.. Identification of Transcription Factor Binding Sites in Streptomyces coelicolor A3(2) by Phylogenetic Comparison. European Conference for Computer Biology - ECCB'2003, 2003, Paris, France. ⟨inria-00099608⟩
  • Patricia Lavigne, Isabelle Debled-Rennesson, Bertrand Aigle, Pierre Leblond, Gregory Kucherov. Identification of transcription factor binding sites in the genome of Streptomyces coelicolor A3(2). 3ème Journées Post-Génomique de la DOUA 2003 - JPGD'03, 2003, Lyon, France. ⟨inria-00099609⟩
  • Sébastien Hergalant, Bertrand Aigle, Bernard Decaris, Jean-François Mari, Pierre Leblond. HMM, an Efficient Way to Detect Transcriptional Promoters in Bacterial Genomes?. European Conference on Computational Biology - ECCB'2003, Sep 2003, Paris, France, pp.417--419. ⟨inria-00099570⟩
  • Sébastien Hergalant, Bertrand Aigle, Bernard Decaris, Pierre Leblond, Jean-François Mari. Intragenomic reiterations detection using hidden Markov models. 10th International Conference on Intelligent Systems for Molecular Biology - ISMB 2002, Aug 2002, Edmonton, Canada, 1 p. ⟨inria-00100914⟩
  • Sébastien Hergalant, Bertrand Aigle, Bernard Decaris, Pierre Leblond, Jean-François Mari. Fouille de données à l'aide de HMM : Application à la détection de réitérations intragénomiques. Journées Ouvertes Biologie Informatique Mathématiques - JOBIM'02, François Coste - Elisabeth Lebret, 2002, Saint Malo, France, pp.269-273. ⟨inria-00100752⟩

Poster communications4 documents

  • Li Su, Hotel L, Christophe Jacob, Kira J Weissman, Bertrand Aigle. Creating analogues of the anti-tumor polyketide stambomycins by genetic engineering and allied approaches. 2018, 2018, Nancy, France. ⟨hal-03016980⟩
  • Cláudia M Vicente, Matthieu Barba, Drago Haas, Sylvie Lautru, Olivier Lespinet, et al.. Searching for novel specialized metabolite gene clusters, a new comparative genomics-based approach. Directing Biosynthesis V, Mar 2017, Warwick, United Kingdom. ⟨hal-03042555⟩
  • Milena Gonzalo, Aurélie Deveau, Bertrand Aigle. Towards the understanding of molecular dialogues within soil forest microbial communities and their impact on plants. Actino2017, Oct 2017, Lyon, France. ⟨hal-02948434⟩
  • Frédéric Choulet, Bertrand Aigle, F. X. Francou, Alexandre Gallois, Céline Fourrier, et al.. Evidence for a High Heterogeneity Between the Terminal Regions of the Chromosomes of Two Phylogenetically Close Species, Streptomyces ambofaciens and Streptomyces coelicolor by Genome Comparison. Streptomyces dissemination meeting, Jul 2003, Guilford, United Kingdom. 2003, Streptomyces dissemination meeting. ⟨hal-01182814⟩

Book sections3 documents

  • Bertrand Aigle, Christophe Corre. Waking up Streptomyces Secondary Metabolism by Constitutive Expression of Activators or Genetic Disruption of Repressors. Natural product biosynthesis by microorganisms and plants, part C, 517, Academic Press, 2012, Methods in Enzymology, ⟨10.1016/B978-0-12-404634-4.00017-6⟩. ⟨hal-02809379⟩
  • Bertrand Aigle, Robert Bunet, Christophe Corre, Amélie Garenaux, S. Huang, et al.. Genome-guided Exploration of Streptomyces ambofaciens Secondary Metabolism. Paul J Dyson Institute of Life Sciences, School of Medicine, Swansea, UK. Streptomyces: Molecular Biology and Biotechnology, Caister Academic Press, Chapter 10 pp. 179-194, 2011, 978-1-904455-77-6. ⟨hal-01667184⟩
  • Sébastien Hergalant, Bertrand Aigle, Pierre Leblond, Jean-François Mari. Fouille de données du génome à l'aide de modèles de Markov cachés. Extraction et gestion des connaissances. EGC 2005, Cépaduès, 2005, Revue des Nouvelles Technologies de l'Information, 2-85428-677-4 2-85428-682-0 (vol. 1) 2-85428-683-9 (vol. 2). ⟨hal-02832934⟩

Patents1 document

  • Bertrand Aigle, Gregory L Challis, Luisa Laureti, Lijiang Song, Pierre Leblond. Stambomycin and derivatives: their production and their use as drugs. France, Patent n° : WO2011009938. 2011. ⟨hal-01655316⟩

Other publications1 document

  • Pierre Leblond, Nathalie Leblond-Bourget, Sophie Payot, Bertrand Aigle. La folle course aux armements des bactéries contre les antibiotiques. 2018. ⟨hal-01889239⟩

Theses1 document

  • Bertrand Aigle. Instabilité génétique chez streptomyces ambofaciens : expression de deux loci amplifiables et délétables, implication possible de RecA dans l'instabilité. Génomique, Transcriptomique et Protéomique [q-bio.GN]. Université Henri Poincaré - Nancy 1, 1995. Français. ⟨NNT : 1995NAN10315⟩. ⟨tel-01753746⟩