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Studying Drug-Tubulin Interactions by X-Ray Crystallography
Audrey Dorleans
,
Marcel Knossow
,
Benoît Gigant
Microtubule Protocols, pp.235-243, 2007
Chapitre d'ouvrage
hal-02109642v1
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Structure of a kinesin–tubulin complex and implications for kinesin motility
Benoît Gigant
,
Weiyi Wang
,
Birgit Dreier
,
Qiyang Jiang
,
Ludovic Pecqueur
,
et al.
Article dans une revue
hal-02121652v1
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GTP-dependent formation of straight oligomers leads to nucleation of microtubules
Rie Ayukawa
,
Seigo Iwata
,
Hiroshi Imai
,
Shinji Kamimura
,
Masahito Hayashi
,
et al.
2020
Pré-publication, Document de travail
hal-02990991v1
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N-Terminal Stathmin-like Peptides Bind Tubulin and Impede Microtubule Assembly
Marie-Jeanne Clément
,
Isabelle Jourdain
,
Sylvie Lachkar
,
Philippe Savarin
,
Benoît Gigant
,
et al.
Article dans une revue
istex
hal-02120587v1
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Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery
Yuxi Wang
,
Hang Zhang
,
Benoît Gigant
,
Yamei Yu
,
Yangping Wu
,
et al.
Article dans une revue
hal-01432123v1
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Catalytic Antibodies
Benoît Gigant
,
Marcel Knossow
John Wiley & Sons, Ltd, 2001, Encyclopedia of Life Sciences
Ouvrages
hal-02117635v1
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The Binding of Vinca Domain Agents to Tubulin
Anthony Cormier
,
Marcel Knossow
,
Chunguang Wang
,
Benoît Gigant
Microtubules, in vitro, pp.373-390, 2010
Chapitre d'ouvrage
hal-02117601v1
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Kif2C minimal functional domain has unusual nucleotide binding properties that are adapted to microtubule depolymerization.
Weiyi Wang
,
Qiyang Jiang
,
Manuela Argentini
,
David Cornu
,
Benoît Gigant
,
et al.
Article dans une revue
hal-00741318v1
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The beta-thymosin/WH2 domain; structural basis for the switch from inhibition to promotion of actin assembly.
Maud Hertzog
,
Carine van Heijenoort
,
Dominique Didry
,
Martin Gaudier
,
Jérôme Coutant
,
et al.
Article dans une revue
hal-00121857v1
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X-Ray structures of two families of hydrolytic antibodies
Benoît Gigant
,
Jean-Baptiste Charbonnier
,
Béatrice Golinelli-Pimpaneau
,
Z. Eshhar
,
Bernard Green
,
et al.
Article dans une revue
istex
hal-02109618v1
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Insight into microtubule disassembly by kinesin-13s from the structure of Kif2C bound to tubulin
Weiyi Wang
,
Soraya Cantos-Fernandes
,
Yuncong Lv
,
Hureshitanmu Kuerban
,
Shoeb Ahmad
,
et al.
Article dans une revue
hal-02123770v1
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Selection and Characterization of Artificial Proteins Targeting the Tubulin α Subunit
Valérie Campanacci
,
Agathe Urvoas
,
Tanja Consolati
,
Soraya Cantos-Fernandes
,
Magali Aumont-Nicaise
,
et al.
Article dans une revue
hal-02123773v1
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Engineering of brick and staple components for ordered assembly of synthetic repeat proteins
Jessalyn Miller
,
Agathe Urvoas
,
Benoît Gigant
,
Malika Ouldali
,
Ana Arteni
,
et al.
Article dans une revue
hal-04210030v1
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Structural insight into the inhibition of tubulin by vinca domain peptide ligands
Anthony Cormier
,
Matthieu Marchand
,
Raimond Ravelli
,
Marcel Knossow
,
Benoît Gigant
Article dans une revue
hal-02120591v1
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Systematic identification of tubulin interacting fragments of the microtubule-associated protein TAU leads to a highly efficient promoter of microtubule assembly.
Caroline Fauquant
,
Virginie Redeker
,
Isabelle Landrieu
,
Jean-Michel Wieruzseski
,
Dries Verdegem
,
et al.
Article dans une revue
hal-00618268v1
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Bases structurales de la régulation de la tubuline par un médicament anticancéreux, la vinblastine
Benoît Gigant
,
Chunguang Wang
,
Raimond Ravelli
,
Marcel Knossow
Article dans une revue
hal-02111440v1
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Insight into the GTPase Activity of Tubulin from Complexes with Stathmin-like Domains
Chunguang Wang
,
Anthony Cormier
,
Benoît Gigant
,
Marcel Knossow
Article dans une revue
istex
hal-02119493v1
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A synergistic relationship between three regions of stathmin family proteins is required for the formation of a stable complex with tubulin
Isabelle Jourdain
,
Sylvie Lachkar
,
Elodie Charbaut
,
Benoît Gigant
,
Marcel Knossow
,
et al.
Article dans une revue
hal-02118404v1
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Elucidating Tau function and dysfunction in the era of cryo-EM
Guy Lippens
,
Benoît Gigant
Article dans une revue
hal-02137974v1
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The Determinants That Govern Microtubule Assembly from the Atomic Structure of GTP-Tubulin
Agata Nawrotek
,
Marcel Knossow
,
Benoît Gigant
Article dans une revue
istex
hal-02120600v1
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Variations in the colchicine-binding domain provide insight into the structural switch of tubulin
Audrey Dorleans
,
Benoît Gigant
,
Raimond Ravelli
,
Patrick Mailliet
,
Vincent Mikol
,
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2009, 106 (33), pp.13775-13779. ⟨10.1073/pnas.0904223106⟩
Article dans une revue
hal-02120597v1
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A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end
Ludovic Pecqueur
,
Christian Duellberg
,
Birgit Dreier
,
Qiyang Jiang
,
Chunguang Wang
,
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (30), pp.12011-12016. ⟨10.1073/pnas.1204129109⟩
Article dans une revue
hal-02121638v1
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New Insights into the Coupling between Microtubule Depolymerization and ATP Hydrolysis by Kinesin-13 Protein Kif2C.
Weiyi Wang
,
Ting Shen
,
Raphaël Guérois
,
Fuming Zhang
,
Hureshitanmu Kuerban
,
et al.
Article dans une revue
hal-01446760v1
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Destabilizing an interacting motif strengthens the association of a designed ankyrin repeat protein with tubulin
Shoeb Ahmad
,
Ludovic Pecqueur
,
Birgit Dreier
,
Djemel Hamdane
,
Magali Aumont-Nicaise
,
et al.
Article dans une revue
hal-01356073v1
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Kinesin, 30 years later: Recent insights from structural studies.
Weiyi Wang
,
Luyan Cao
,
Chunguang Wang
,
Benoît Gigant
,
Marcel Knossow
Article dans une revue
hal-01447800v1
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Insight into microtubule nucleation from tubulin-capping proteins
Valérie Campanacci
,
Agathe Urvoas
,
Soraya Cantos-Fernandes
,
Magali Aumont-Nicaise
,
Ana-Andreea Arteni
,
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2019, pp.201813559. ⟨10.1073/pnas.1813559116⟩
Article dans une revue
hal-02123790v1
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B-nor-methylene Colchicinoid PT-100 Selectively Induces Apoptosis in Multidrug-Resistant Human Cancer Cells via an Intrinsic Pathway in a Caspase-Independent Manner
Andreas Stein
,
Persefoni Hilken Née Thomopoulou
,
Corazon Frias
,
Sina M Hopff
,
Paloma Varela
,
et al.
Article dans une revue
hal-03829931v1
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Structural plasticity of tubulin assembly probed by vinca-domain ligands
Fanomezana M Ranaivoson
,
Benoît Gigant
,
Simon Berritt
,
Madeleine Joullié
,
Marcel Knossow
Article dans une revue
istex
hal-02120601v1
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Remarkable remote chiral recognition in a reaction mediated by a catalytic antibody.
Lawrence d'Souza
,
Benoît Gigant
,
Marcel Knossow
,
Bernard Green
Journal of the American Chemical Society, 2002, 124 (10), pp.2114-5
Article dans une revue
hal-02118377v1
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Mechanism of Inactivation of a Catalytic Antibody by P-Nitrophenyl Esters
Benoît Gigant
,
Jean-Baptiste Charbonnier
,
Béatrice Golinelli-Pimpaneau
,
Romy Zemel
,
Zelig Eshhar
,
et al.
Article dans une revue
hal-02111429v1
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