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Benjamin Rohaut

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Présentation

Dr. Benjamin Rohaut M.D. Ph.D. Neurointensivist and Neuroscientist Department of Neurology, Neuro-ICU, Pitié-Salpêtrière Hospital (AP-HP), Sorbonne Université & Brain Institute, Paris 75013, FRANCE Tel: (+33)1 84 82 78 88; email: benjamin.rohaut@aphp.fr ; benjamin.rohaut@sorbonne-universite.fr RPPS number: 10100108686; GCP certificate (with ICH GCP R2) Professional Experience - \- Associate Professor of Neurology at Sorbonne University, Paris; 2019 - Current position - \- Attending Physician in Neuro-ICU, Department of Neurology, Pitié-Salpêtrière Hospital - AP-HP, Paris; 2019- Current position - \- Adjunct Research Scientist in Neuro-ICU at Columbia University, New York; 2018 - Current position - \- Post-doc Research Scientist in Neuro-ICU at Columbia University, New York; 2017- 2018 - \- Post-doc Research Fellow in Neuro-ICU at Columbia University, New York; 2016 - 2017 - \- Post-doc Research Scientist at Brain Institute (ICM), Paris; 2015 - 2016 - \- Clinical Fellow - Assistant Professor in Neuro-ICU (CCA); Neurological Department of La Pitié- Salpêtrière Hospital (AP-HP), University Pierre et Marie Curie (UPMC); 2012 - 2015 - \- Ph.D. candidate in Cognitive Neuroscience at ICM; 2010 - 2015 - \- Clinical Fellow in general ICU (PHC) at La Pitié-Salpêtrière Hospital, Paris; 2009 - 2010 - Education - \- Ph.D. in Cognitive Neuroscience, Pierre et Marie Curie University, UPMC- Paris, 2015 - \- M.D. in Neurology (DES, 2009) & Intensive Care Medicine (DESC, 2013) Scientific Publications N=51; h-index:17; citation:1943 (Google Scholar) Selected 5 publications : - Claassen J, Doyle K, Matory A, ..., Rohaut B. Detection of Brain Activation in Unresponsive Patients with Acute Brain Injury. N Engl J Med. 2019 Jun 27;380(26):2497-2505. - Hermann B\*, Goudard G\*, Courcoux K\*, Valente M, Labat S, ..., Rohaut B. Wisdom of the caregivers: pooling individual subjective reports to diagnose states of consciousness in brain-injured patients, a monocentric prospective study. BMJ Open. 2019 Feb 21;9(2):e026211. - Rohaut B, Eliseyev A, Claassen J. Uncovering Consciousness in Unresponsive ICU Patients: Technical, Medical and Ethical Considerations. Crit Care. 2019 Mar 9;23(1):78. - Rohaut B, Doyle KW, Reynolds AS, et al. Deep structural brain lesions associated with consciousness impairment early after hemorrhagic stroke. Sci Rep. 2019 Mar 12;9(1):4174 - Rohaut B, Alario F-X, Meadow J, Cohen L, Naccache L. Unconscious semantic processing of polysemous words is not automatic. Neuroscience of Consciousness. 2016(1):niw010. Professional Memberships SRLF (French Intensive Care Medicine Society); SFN (French Neurological Society); EAN (European Academy of Neurology); NCS (Neurocritical Care Society) Peer reviewing N=63; details available on https://publons.com/a/1235063/ August 2020

Publications

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Heuristics and biases in medical decision-making under uncertainty: The case of neuropronostication for consciousness disorders

Camille Lakhlifi , Benjamin Rohaut
La Presse Médicale, 2023, 52 (2), pp.104181. ⟨10.1016/j.lpm.2023.104181⟩
Article dans une revue hal-04290464v1
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Valproic acid as adjuvant treatment for convulsive status epilepticus: a randomised clinical trial

Tarek Sharshar , Raphaël Porcher , Pierre Asfar , Lamiae Grimaldi , Julien Jabot
Critical care (London, England), 2023, 27 (1), ⟨10.1186/s13054-022-04292-7⟩
Article dans une revue hal-03949580v1
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A Novel Approach to Screen for Somatosensory Evoked Potentials in Critical Care

Aude Sangare , Benjamin Rohaut , Alaina Borden , Julie Zyss , Angela Velazquez
Neurocritical Care, 2023, ⟨10.1007/s12028-023-01710-8⟩
Article dans une revue hal-04314658v2
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Illusion of knowledge in statistics among clinicians: evaluating the alignment between objective accuracy and subjective confidence, an online survey

Camille Lakhlifi , François-Xavier Lejeune , Marion Rouault , Mehdi Khamassi , Benjamin Rohaut
Cognitive Research: Principles and Implications, 2023, 8, ⟨10.1186/s41235-023-00474-1⟩
Article dans une revue hal-04076913v1
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Disorders of Consciousness: navigating between nihilism and unrealistic hopes

Benjamin Rohaut
La Presse Médicale, 2023, 52 (2), pp.104182. ⟨10.1016/j.lpm.2023.104182⟩
Article dans une revue hal-04273414v1

Intravenous immunoglobulins in patients with COVID-19-associated moderate-to-severe acute respiratory distress syndrome (ICAR): multicentre, double-blind, placebo-controlled, phase 3 trial

Aurélien Mazeraud , Matthieu Jamme , Rossella Letizia Mancusi , Claire Latroche , Bruno Megarbane
The Lancet Respiratory Medicine, 2022, 10 (2), pp.158-166. ⟨10.1016/S2213-2600(21)00440-9⟩
Article dans une revue hal-03579483v1
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Shaping the future of neurocritical care in France

Benjamin Rohaut , Sophie Demeret
Revue Neurologique, 2022, 178 (1-2), pp.7-8. ⟨10.1016/j.neurol.2022.01.004⟩
Article dans une revue hal-03582656v1
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Brain Biopsy for Neurological Diseases of Unknown Etiology in Critically Ill Patients

Bertrand Mathon , Malory Favreau , Vincent Degos , Aymeric Amelot , Alexandre Le Joncour
Critical Care Medicine, inPress, ⟨10.1097/CCM.0000000000005439⟩
Article dans une revue hal-03520976v1
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Older patients with COVID‐19 and neuropsychiatric conditions: A study of risk factors for mortality

Vi‐huong Nguyen‐michel , Marion Houot , Cécile Delorme , Aude Sangaré , Ana Gales
Brain and Behavior, 2022, 12 (12), ⟨10.1002/brb3.2787⟩
Article dans une revue hal-04146192v1
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Shaping the future of neurocritical care in France

Benjamin Rohaut , Sophie Demeret
Revue Neurologique, 2022, 178 (1-2), pp.7-8. ⟨10.1016/j.neurol.2022.01.004⟩
Article dans une revue hal-03589023v1
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Endothelial cell biomarkers in critically ill COVID‐19‐patients with encephalitis

Victor Altmayer , Jason Ziveri , Corinne Frère , Joe‐elie Salem , Nicolas Weiss
Journal of Neurochemistry, In press, ⟨10.1111/jnc.15545⟩
Article dans une revue hal-03452050v1
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Does adding beer to coffee enhance the activation of drinks ? An ERP study of semantic category priming

Marcela Ovando-Tellez , Benjamin Rohaut , Nathalie George , Theophile Bieth , Laurent Hugueville
Cognitive Neuroscience, 2021, pp.1-16. ⟨10.1080/17588928.2021.1940117⟩
Article dans une revue hal-03282300v1
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Coronavirus disease 2019 crisis in Paris: A differential psychological impact between regular intensive care unit staff members and reinforcement workers

Victor Altmayer , Nicolas Weiss , Albert Cao , Clémence Marois , Sophie Demeret
Australian Critical Care, 2021, 34 (2), pp.142-145. ⟨10.1016/j.aucc.2020.11.005⟩
Article dans une revue hal-03184560v1
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Serum Neuron Specific Enolase: a new tool for seizure risk monitoring after status epilepticus

Aurélie Hanin , Sophie Demeret , Jérôme Alexandre Denis , Vi-Huong Nguyen-Michel , Benjamin Rohaut
European Journal of Neurology, 2021, ⟨10.1111/ene.15154⟩
Article dans une revue hal-03405653v1
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Not all patients with convulsive status epilepticus intubated in pre-hospital settings meet the criteria for refractory status epilepticus

Sinead Zeidan , Benjamin Rohaut , Hervé Outin , Francis Bolgert , Marion Houot
Seizure - European Journal of Epilepsy, 2021, 88, pp.29-35. ⟨10.1016/j.seizure.2021.03.015⟩
Article dans une revue hal-04396404v2
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Valproic Acid as an Adjuvant Treatment for Generalized Convulsive Status Epilepticus in Adults Admitted to Intensive Care Units: Protocol for a Double-Blind, Multicenter Randomized Controlled Trial

Tarek Sharshar , Omar Ben Hadj Salem , Raphaël Porcher , Lamiae Grimaldi-Bensouda , Nicholas Heming
JMIR Research Protocols, 2021, 10 (2), pp.e22511. ⟨10.2196/22511⟩
Article dans une revue hal-03152358v1
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Multimodal FDG-PET and EEG assessment improves diagnosis and prognostication of disorders of consciousness

Bertrand Hermann , Johan Stender , Marie-Odile Habert , Aurélie Kas , Mélanie Denis-Valente
Neuroimage-Clinical, 2021, 30, pp.102601. ⟨10.1016/j.nicl.2021.102601⟩
Article dans une revue hal-03157892v1
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Auditory Event-Related "Global Effect" Predicts Recovery of Overt Consciousness

Pauline Perez , Mélanie Valente , Bertrand Hermann , Jacobo Sitt , Frédéric Faugeras
Frontiers in Neurology, 2021, 11, pp.588233. ⟨10.3389/fneur.2020.588233⟩
Article dans une revue hal-03145838v1
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The wide spectrum of COVID-19 neuropsychiatric complications within a multidisciplinary centre

Cécile Delorme , Marion Houot , Charlotte Rosso , Stéphanie Carvalho , Thomas Nedelec
Brain Communications, 2021, 3 (3), ⟨10.1093/braincomms/fcab135⟩
Article dans une revue hal-03464402v1
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Home-based exercise in autoimmune myasthenia gravis: A randomized controlled trial

S Birnbaum , R Porcher , P Portero , B Clair , S Demeret
Neuromuscular Disorders, 2021, 31 (8), pp.726-735. ⟨10.1016/j.nmd.2021.05.002⟩
Article dans une revue hal-03442076v1
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Characteristics, management, and prognosis of elderly patients with COVID-19 admitted in the ICU during the first wave: insights from the COVID-ICU study

Martin Dres , David Hajage , Saïd Lebbah , Antoine Kimmoun , Tài Pham
Annals of Intensive Care, 2021, 11 (1), ⟨10.1186/s13613-021-00861-1⟩
Article dans une revue hal-03524638v1
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Disturbances of brain cholesterol metabolism: A new excitotoxic process associated with status epilepticus

Aurélie Hanin , Paul Baudin , Sophie Demeret , Delphine Roussel , Sarah Lecas
Neurobiology of Disease, 2021, pp.105346. ⟨10.1016/j.nbd.2021.105346⟩
Article dans une revue hal-03184494v1

Therapeutic plasma exchange in a critically ill Covid‐19 patient

Victor Altmayer , Samir Saheb , Benjamin Rohaut , Clémence Marois , Albert Cao
Journal of Clinical Apheresis, 2020, ⟨10.1002/jca.21830⟩
Article dans une revue hal-02938993v1
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Early abolition of cough reflex predicts mortality in deeply sedated brain-injured patients

Stanislas Kandelman , Jérémy Allary , Raphael Porcher , Cássia Righy , Clarissa Francisca Valdez
PeerJ, 2020, 8, pp.e10326. ⟨10.7717/peerj.10326⟩
Article dans une revue hal-04504779v1
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Neuroprognostication of Consciousness Recovery in a Patient with COVID-19 Related Encephalitis: Preliminary Findings from a Multimodal Approach

Aude Sangare , Anceline Dong , Mélanie Valente , Nadya Pyatigorskaya , Albert Cao
Brain Sciences, 2020, 10 (11), pp.845. ⟨10.3390/brainsci10110845⟩
Article dans une revue hal-03053495v1

Orbitofrontal involvement in a neuroCOVID‐19 patient

Loïc Le Guennec , Julia Devianne , Laurence Jalin , Albert Cao , Damien Galanaud
Epilepsia, 2020, 61 (8), ⟨10.1111/epi.16612⟩
Article dans une revue hal-02934690v1
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Brainstem dysfunction in critically ill patients

Sarah Benghanem , Aurélien Mazeraud , Eric Azabou , Vibol Chhor , Cassia Righy Shinotsuka
Critical Care, 2020, 24 (1), pp.5. ⟨10.1186/s13054-019-2718-9⟩
Article dans une revue inserm-02461161v1
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Severe COVID-19-related encephalitis can respond to immunotherapy

Albert Cao , Benjamin Rohaut , Loïc Le Guennec , Samir Saheb , Clémence Marois
Brain - A Journal of Neurology , 2020, ⟨10.1093/brain/awaa337⟩
Article dans une revue hal-02918661v4
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Habituation of auditory startle reflex is a new sign of minimally conscious state

Bertrand Hermann , Amina Ben Salah , Vincent Perlbarg , Mélanie Valente , Nadya Pyatigorskaya
Brain - A Journal of Neurology , In press, 143 (7), pp.2154-2172. ⟨10.1093/brain/awaa159⟩
Article dans une revue hal-02886037v1

Combined behavioral and electrophysiological evidence for a direct cortical effect of prefrontal tDCS on disorders of consciousness

Bertrand Hermann , Federico Raimondo , Lukas Hirsch , Yu Huang , Mélanie Valente
Scientific Reports, 2020, ⟨10.1101/612309⟩
Article dans une revue hal-02107872v1
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Deep structural brain lesions associated with consciousness impairment early after hemorrhagic stroke

Benjamin Rohaut , Kevin W Doyle , Alexandra S Reynolds , Kay Igwe , Caroline Couch
Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-41042-2⟩
Article dans une revue hal-02299911v1
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Wisdom of the caregivers: pooling individual subjective reports to diagnose states of consciousness in brain-injured patients, a monocentric prospective study

Bertrand Hermann , Gwen Goudard , Karine Courcoux , Mélanie Valente , Sébastien Labat
BMJ Open, 2019, 9 (2), pp.e026211. ⟨10.1136/bmjopen-2018-026211⟩
Article dans une revue hal-02299913v1
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Detection of Brain Activation in Unresponsive Patients with Acute Brain Injury

Jan Claassen , Kevin Doyle , Adu Matory , Caroline Couch , Kelly Burger
New England Journal of Medicine, 2019, 380 (26), pp.2497-2505. ⟨10.1056/NEJMoa1812757⟩
Article dans une revue hal-02299909v1
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Uncovering Consciousness in Unresponsive ICU Patients: Technical, Medical and Ethical Considerations

Benjamin Rohaut , Andrey Eliseyev , Jan Claassen
Critical Care, 2019, 23 (1), ⟨10.1186/s13054-019-2370-4⟩
Article dans une revue hal-02299912v1
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Mismatch negativity to predict subsequent awakening in deeply sedated critically ill patients

Eric Azabou , Benjamin Rohaut , Raphael Porcher , Nicholas Heming , Stanislas Kandelman
British Journal of Anaesthesia, 2018, 121 (6), pp.1290-1297. ⟨10.1016/j.bja.2018.06.029⟩
Article dans une revue hal-01868795v1

Recommendations for the use of electroencephalography and evoked potentials in comatose patients

Nathalie André-Obadia , Julie Zyss , Martine Gavaret , Jean-Pascal Lefaucheur , Eric Azabou
Neurophysiologie Clinique = Clinical Neurophysiology, 2018, 48 (3), pp.143-169. ⟨10.1016/j.neucli.2018.05.038⟩
Article dans une revue hal-01859718v1

Early myoclonus following anoxic brain injury

Alexandra S Reynolds , Benjamin Rohaut , Manisha G Holmes , David Robinson , William Roth
Neurology: Clinical Practice, 2018, 8 (3), pp.249 - 256. ⟨10.1212/CPJ.0000000000000466⟩
Article dans une revue hal-01865879v1

Robust EEG-based cross-site and cross-protocol classification of states of consciousness

Denis Engemann , Federico Raimondo , Jean-Remi King , Benjamin Rohaut , Gilles Louppe
Brain - A Journal of Neurology , 2018, 141 (11), pp.3179-3192. ⟨10.1093/brain/awy251⟩
Article dans une revue hal-01887793v1

Use of brain diffusion tensor imaging for the prediction of long-term neurological outcomes in patients after cardiac arrest: a multicentre, international, prospective, observational, cohort study

Lionel Velly , Vincent Perlbarg , Thomas Boulier , Nicolas Adam , Sebastien Delphine
The Lancet Neurology, 2018, 17 (4), pp.317 - 326. ⟨10.1016/S1474-4422(18)30027-9⟩
Article dans une revue hal-01788066v1
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What are the boundaries of unconscious semantic cognition?

Benjamin Rohaut , Lionel Naccache
European Journal of Neuroscience, 2018, 47 (11), pp.1287 - 1288. ⟨10.1111/ejn.13930⟩
Article dans une revue hal-01865877v1
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Decision making in perceived devastating brain injury: a call to explore the impact of cognitive biases

Benjamin Rohaut , Jan Claassen
British Journal of Anaesthesia, 2018, 120 (1), pp.5-9. ⟨10.1016/j.bja.2017.11.007⟩
Article dans une revue hal-01865865v1
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Une jeune femme présentant des symptômes psychiatriques subaigus aux urgences

Alexandra Grinea , Sophie Demeret , Francis Bolgert , Romain Sonneville , Benjamin Rohaut
Revue du Praticien (La), 2017
Article dans une revue hal-01865882v1

Brain-heart interactions reveal consciousness in noncommunicating patients

Federico Raimondo , Benjamin Rohaut , Athena Demertzi , Mélanie Valente , Denis Engemann
Annals of Neurology, 2017, 82 (4), pp.578 - 591. ⟨10.1002/ana.25045⟩
Article dans une revue hal-01848059v1
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Disentangling conscious from unconscious cognitive processing with event-related EEG potentials

Benjamin Rohaut , Lionel Naccache
Revue Neurologique, 2017, ⟨10.1016/j.neurol.2017.08.001⟩
Article dans une revue hal-01580615v1

Survival and consciousness recovery are better in the minimally conscious state than in the vegetative state

Frédéric Faugeras , Benjamin Rohaut , Mélanie Valente , Jacobo Sitt , Sophie Demeret
Brain Injury, 2017, 32 (1), pp.72 - 77. ⟨10.1080/02699052.2017.1364421⟩
Article dans une revue hal-01848286v1
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Multidimensional cognitive evaluation of patients with disorders of consciousness using EEG: A proof of concept study

Claire Sergent , Frédéric Faugeras , Benjamin Rohaut , Fabien Perrin , Mélanie Valente
Neuroimage-Clinical, 2017, 13, pp.455-469. ⟨10.1016/j.nicl.2016.12.004⟩
Article dans une revue hal-01534718v1
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Probing consciousness in a sensory-disconnected paralyzed patient

Benjamin Rohaut , Federico Raimondo , Damien Galanaud , Mélanie Valente , Jacobo Diego Sitt
Brain Injury, 2017, pp.1-6. ⟨10.1080/02699052.2017.1327673⟩
Article dans une revue hal-01558164v1

Encephalitis in a traveller with typhoid fever: efficacy of corticosteroids

Guillaume Mellon , Anne-Line Eme , Benjamin Rohaut , Florence Brossier , Loïc Epelboin
Journal of Travel Medicine, 2017, 24 (6), ⟨10.1093/jtm/tax063⟩
Article dans une revue hal-01844528v1
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Brainstem response patterns in deeply-sedated critically-ill patients predict 28-day mortality

Benjamin Rohaut , Raphael Porcher , Tarik Hissem , Nicholas Heming , Patrick Chillet
PLoS ONE, 2017, 12 (4), pp.e0176012. ⟨10.1371/journal.pone.0176012⟩
Article dans une revue hal-01528608v1

Unconscious semantic processing of polysemous words is not automatic

Benjamin Rohaut , F. -Xavier Alario , Jacqueline Meadow , Laurent Cohen , Lionel Naccache
Neuroscience of Consciousness, 2016, 1, ⟨10.1093/nc/niw010⟩
Article dans une revue hal-01432283v1

Reply: Replicability and impact of statistics in the detection of neural responses of consciousness

Lionel Naccache , Jacobo Sitt , Jean-Rémi King , Benjamin Rohaut , Frédéric Faugeras
Brain - A Journal of Neurology , 2016, 139 (6), pp.e31 - e31. ⟨10.1093/brain/aww060⟩
Article dans une revue hal-01865889v1

Neural detection of complex sound sequences or of statistical regularities in the absence of consciousness?

Lionel Naccache , Jean-Rémi King , Jacobo D Sitt , Denis Engemann , Imen El Karoui
Brain - A Journal of Neurology , 2015, 138 (12), pp.e395 - e395. ⟨10.1093/brain/awv190⟩
Article dans une revue hal-01865887v1

Large scale screening of neural signatures of consciousness in patients in a vegetative or minimally conscious state

Jacobo Diego Sitt , Jean-Rémi King , Imen El Karoui , Benjamin Rohaut , Frédéric Faugeras
Brain - A Journal of Neurology , 2014, 137 (8), pp.2258 - 2270. ⟨10.1093/brain/awu141⟩
Article dans une revue hal-01865883v1

Single-trial decoding of auditory novelty responses facilitates the detection of residual consciousness

Jean-Rémi King , Frédéric Faugeras , Alexandre Gramfort , A. Schurger , Imen El Karoui
NeuroImage, 2013, 83 (3), pp.726 - 738. ⟨10.1016/j.neuroimage.2013.07.013⟩
Article dans une revue hal-01865885v1

Information Sharing in the Brain Indexes Consciousness in Noncommunicative Patients

Jean-Rémi King , Jacobo D Sitt , Frédéric Faugeras , Benjamin Rohaut , Imen El karoui
Current Biology - CB, 2013, 23 (19), pp.1914 - 1919. ⟨10.1016/j.cub.2013.07.075⟩
Article dans une revue hal-01865886v1
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Event related potentials elicited by violations of auditory regularities in patients with impaired consciousness.

Frédéric Faugeras , Benjamin Rohaut , Nicolas Weiss , Tristan Bekinschtein , Damien Galanaud
Neuropsychologia, 2012, 50 (3), pp.403-18. ⟨10.1016/j.neuropsychologia.2011.12.015⟩
Article dans une revue hal-00719338v1

Neural signature of the conscious processing of auditory regularities

Tristan A Bekinschtein , Stanislas Dehaene , Benjamin Rohaut , Francois Tadel , Laurent Cohen
Proceedings of the National Academy of Sciences of the United States of America, 2009, 106 (5), pp.1672 - 1677. ⟨10.1073/pnas.0809667106⟩
Article dans une revue hal-01865884v1