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Bacterial Metabolism under FHA Control

Marco Bellinzoni , Pedro M. Alzari
Structure, 2009, 17 (4), pp.487-488. ⟨10.1016/j.str.2009.03.004⟩
Article dans une revue pasteur-03139144v1

Functional Plasticity and Allosteric Regulation of α-Ketoglutarate Decarboxylase in Central Mycobacterial Metabolism

Tristan Wagner , Marco Bellinzoni , Annemarie Wehenkel , Helen M. O'Hare , Pedro M. Alzari
Chemistry & biology, 2011, 18 (8), pp.1011-1020. ⟨10.1016/j.chembiol.2011.06.004⟩
Article dans une revue pasteur-03137931v1

Regulation of glutamate metabolism by protein kinases in mycobacteria

Helen O'Hare , Rosario Durán , Carlos Cerveñansky , Marco Bellinzoni , Anne Marie Wehenkel , et al.
Molecular Microbiology, 2008, 70 (6), pp.1408-1423. ⟨10.1111/j.1365-2958.2008.06489.x⟩
Article dans une revue pasteur-03139167v1

Rv2686c-Rv2687c-Rv2688c, an ABC Fluoroquinolone Efflux Pump in Mycobacterium tuberculosis

Maria Rosalia Pasca , Paola Guglierame , Fabio Arcesi , Marco Bellinzoni , Edda de Rossi , et al.
Antimicrobial Agents and Chemotherapy, 2004, 48 (8), pp.3175-3178. ⟨10.1128/AAC.48.8.3175-3178.2004⟩
Article dans une revue pasteur-03257773v1

Reconstitution of T-cell receptor repertoire diversity following non-myeloablative allogeneic stem cell transplantation in an acute myeloid leukemia patient.

Camillo Almici , Luisa Imberti , Arnalda Lanfranchi , Rosanna Verardi , Marco Bellinzoni , et al.
Haematologica, 2002, 87 (10), pp.ECR31
Article dans une revue pasteur-03257811v1
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Structure-Based Drug Design for Tuberculosis: Challenges Still Ahead

Eduardo Bruch , Stéphanie Petrella , Marco Bellinzoni
Applied Sciences, 2020, 10 (12), pp.4248. ⟨10.3390/app10124248⟩
Article dans une revue pasteur-03259522v1

Conserved autophosphorylation pattern in activation loops and juxtamembrane regions of Mycobacterium tuberculosis Ser/Thr protein kinases

Rosario Durán , Andrea Villarino , Marco Bellinzoni , Annemarie Wehenkel , Pablo Fernandez , et al.
Biochemical and Biophysical Research Communications, 2005, 333 (3), pp.858-867. ⟨10.1016/j.bbrc.2005.05.173⟩
Article dans une revue istex pasteur-03144581v1

Tolerance of the archaeal Sac7d scaffold protein to alternative library designs: characterization of anti-immunoglobulin G Affitins

Ghislaine Behar , Marco Bellinzoni , Mike Maillasson , Lauranne Paillard-Laurance , Pedro M. Alzari , et al.
Protein Engineering, Design and Selection, 2013, 26 (4), pp.267-275. ⟨10.1093/protein/gzs106⟩
Article dans une revue pasteur-03137902v1
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New insight into structure-activity of furan-based salicylate synthase (MbtI) inhibitors as potential antitubercular agents

Laurent Chiarelli , Matteo Mori , Giangiacomo Beretta , Arianna Gelain , Elena Pini , et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019, 34 (1), pp.823-828. ⟨10.1080/14756366.2019.1589462⟩
Article dans une revue pasteur-03257047v1
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Conformational transitions in the active site of mycobacterial 2-oxoglutarate dehydrogenase upon binding phosphonate analogues of 2-oxoglutarate: From a Michaelis-like complex to ThDP adducts

Tristan Wagner , Alexandra Boyko , Pedro Alzari , Victoria Bunik , Marco Bellinzoni
Journal of Structural Biology, 2019, 208 (2), pp.182-190. ⟨10.1016/j.jsb.2019.08.012⟩
Article dans une revue pasteur-03095849v1
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Secondary structure reshuffling modulates glycosyltransferase function at the membrane

David Giganti , David Albesa-Jové , Saioa Urresti , Ane Rodrigo-Unzueta , Mariano A Martínez , et al.
Nature Chemical Biology, 2014, 11 (1), pp.16 - 18. ⟨10.1038/nchembio.1694⟩
Article dans une revue pasteur-01408804v1

Transmission of SEN virus from mothers to their babies

Silvia Pirovano , Marco Bellinzoni , Cristina Ballerini , Elisabetta Cariani , Marzia Duse , et al.
Journal of Medical Virology, 2002, 66 (3), pp.421-427. ⟨10.1002/jmv.2162⟩
Article dans une revue istex pasteur-03257834v1
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New substrates and interactors of the mycobacterial Serine/Threonine protein kinase PknG identified by a tailored interactomic approach

Magdalena Gil , Analía Lima , Bernardina Rivera , Jéssica Rossello , Estefanía Urdániz , et al.
Journal of Proteomics, 2019, 192, pp.321-333. ⟨10.1016/j.jprot.2018.09.013⟩
Article dans une revue pasteur-02749223v1

Insights into the Catalytic Mechanism of PPM Ser/Thr Phosphatases from the Atomic Resolution Structures of a Mycobacterial Enzyme

Marco Bellinzoni , Annemarie Wehenkel , William Shepard , Pedro M. Alzari
Structure, 2007, 15 (7), pp.863-872. ⟨10.1016/j.str.2007.06.002⟩
Article dans une revue pasteur-03139223v1
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Structural Study of a New MbtI-Inhibitor Complex: Towards an Optimized Model for Structure-Based Drug Discovery

Matteo Mori , Stefania Villa , Laurent Chiarelli , Fiorella Meneghetti , Marco Bellinzoni
Pharmaceuticals, 2023, 16 (11), pp.1559. ⟨10.3390/ph16111559⟩
Article dans une revue pasteur-04366722v1

The structure of PknB in complex with mitoxantrone, an ATP-competitive inhibitor, suggests a mode of protein kinase regulation in mycobacteria.

Annemarie Wehenkel , Pablo Fernandez , Marco Bellinzoni , Vincent Catherinot , Nathalie Barilone , et al.
FEBS Letters, 2006, 580 (13), pp.3018-22. ⟨10.1016/j.febslet.2006.04.046⟩
Article dans une revue istex pasteur-03144516v1

Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling.

Tristan Wagner , Gwenaëlle André-Leroux , Valérie Hindie , Nathalie Barilone , Maria-Natalia Lisa , et al.
Science Signaling, 2019, 12 (580), ⟨10.1126/scisignal.aav9504⟩
Article dans une revue hal-02154615v1
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Ser/Thr Phosphorylation Regulates the Fatty Acyl-AMP Ligase Activity of FadD32, an Essential Enzyme in Mycolic Acid Biosynthesis.

Nguyen-Hung Le , Virginie Molle , Nathalie Eynard , Mathieu Miras , Alexandre Stella , et al.
Journal of Biological Chemistry, 2016, 291 (43), pp.22793-22805. ⟨10.1074/jbc.M116.748053⟩
Article dans une revue hal-01604694v1

Heterologous expression, purification, and enzymatic activity of Mycobacterium tuberculosis NAD+ synthetase

Marco Bellinzoni , Edda de Rossi , Manuela Branzoni , Anna Milano , Fiorenzo Peverali , et al.
Protein Expression and Purification, 2002, 25 (3), pp.547-557. ⟨10.1016/s1046-5928(02)00041-4⟩
Article dans une revue istex pasteur-03257827v1

The multidrug transporters belonging to major facilitator superfamily in Mycobacterium tuberculosis

Edda de Rossi , Patrizio Arrigo , Marco Bellinzoni , Pedro Silva , Carlos Martín , et al.
Molecular Medicine, 2002, 8 (11), pp.714-24. ⟨10.1007/BF03402035⟩
Article dans une revue pasteur-03257806v1

Structural Plasticity and Distinct Drug-Binding Modes of LfrR, a Mycobacterial Efflux Pump Regulator

Marco Bellinzoni , Silvia Buroni , Francis Schaeffer , Giovanna Riccardi , Edda de Rossi , et al.
Journal of Bacteriology, 2009, 191 (24), pp.7531-7537. ⟨10.1128/JB.00631-09⟩
Article dans une revue pasteur-03137957v1

The crystal structure of Mycobacterium tuberculosis adenylate kinase in complex with two molecules of ADP and Mg2+ supports an associative mechanism for phosphoryl transfer.

Marco Bellinzoni , Ahmed Haouz , Martin Graña , Hélène Munier-Lehmann , William Shepard , et al.
Protein Science, 2006, 15 (6), pp.1489-93. ⟨10.1110/ps.062163406⟩
Article dans une revue pasteur-00166948v1
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Shedding X-ray Light on the Role of Magnesium in the Activity of Mycobacterium tuberculosis Salicylate Synthase (MbtI) for Drug Design

Matteo Mori , Giovanni Stelitano , Arianna Gelain , Elena Pini , Laurent Chiarelli , et al.
Journal of Medicinal Chemistry, 2020, 63 (13), pp.7066-7080. ⟨10.1021/acs.jmedchem.0c00373⟩
Article dans une revue pasteur-03257004v1
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The Antibacterial Type VII Secretion System of Bacillus subtilis: Structure and Interactions of the Pseudokinase YukC/EssB

Matteo Tassinari , Thierry Doan , Marco Bellinzoni , Maïalene Chabalier , Mathilde Ben-Assaya , et al.
mBio, 2022, pp.e0013422. ⟨10.1128/mbio.00134-22⟩
Article dans une revue pasteur-03790349v1

Proteome remodeling in the Mycobacterium tuberculosis PknG knockout: Molecular evidence for the role of this kinase in cell envelope biogenesis and hypoxia response

Analía Lima , Alejandro Leyva , Bernardina Rivera , María Magdalena Portela , Magdalena Gil , et al.
Journal of Proteomics, 2021, 244, pp.104276. ⟨10.1016/j.jprot.2021.104276⟩
Article dans une revue pasteur-03256994v1

Structural and Binding Studies of the Three-metal Center in Two Mycobacterial PPM Ser/Thr Protein Phosphatases

Annemarie Wehenkel , Marco Bellinzoni , Francis Schaeffer , Andrea Villarino , Pedro M. Alzari
Journal of Molecular Biology, 2007, 374 (4), pp.890-898. ⟨10.1016/j.jmb.2007.09.076⟩
Article dans une revue istex pasteur-03139199v1

High prevalence of a variant of SENV in intravenous drug user HIV-infected patients

Silvia Pirovano , Marco Bellinzoni , Alberto Matteelli , Cristina Ballerini , Alberto Albertini , et al.
Journal of Medical Virology, 2002, 68 (1), pp.18-23. ⟨10.1002/jmv.10165⟩
Article dans une revue istex pasteur-03257819v1
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Structural Basis for the Binding of Allosteric Activators Leucine and ADP to Mammalian Glutamate Dehydrogenase

Vasily A. Aleshin , Victoria I. Bunik , Eduardo M. Bruch , Marco Bellinzoni
International Journal of Molecular Sciences, 2022, 23 (19), pp.11306. ⟨10.3390/ijms231911306⟩
Article dans une revue pasteur-03789556v1

Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG

Giorgia Mori , Laurent Chiarelli , Marta Esposito , Vadim Makarov , Marco Bellinzoni , et al.
Chemistry and Biology, 2015, 22 (7), pp.917-927. ⟨10.1016/j.chembiol.2015.05.016⟩
Article dans une revue pasteur-03096090v1
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Selective Inhibition of 2-Oxoglutarate and 2-Oxoadipate Dehydrogenases by the Phosphonate Analogs of Their 2-Oxo Acid Substrates

Artem V Artiukhov , Alexey V Kazantsev , Nikolay V Lukashev , Marco Bellinzoni , Victoria Bunik
Frontiers in Chemistry, 2021, 8, pp.596187. ⟨10.3389/fchem.2020.596187⟩
Article dans une revue pasteur-03256999v1