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Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα

 Ning Liang , Anastasius Damdimopoulos , Saioa Goñi , Zhiqiang Huang , Lise-Lotte Vedin , et al.
Nature Communications, 2019, 10 (1), pp.1684. ⟨10.1038/s41467-019-09524-z⟩
Article dans une revue inserm-02154801v1

Expression and functional role of perosome proliferator-activated receptor-gamma in ovarian folliculogenesis in the sheep

 Pascal Froment , Stéphane Fabre , Joëlle Dupont , C. Pisselet , Didier Chesneau , et al.
Biology of Reproduction, 2003, 69 (5), pp.1665-1674. ⟨10.1095/biolreprod.103.017244⟩
Article dans une revue hal-02681583v1
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Rexinoid bexarotene modulates triglyceride but not cholesterol metabolism via gene-specific permissivity of the RXR/LXR heterodimer in the liver.

 Fanny Lalloyer , Thomas Åskov Pedersen , Barbara Gross , Sophie Lestavel , Saïd Yous , et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 2009, 29 (10), pp.1488-95. ⟨10.1161/ATVBAHA.109.189506⟩
Article dans une revue inserm-00410108v1

Beyond the Rule of 5: Impact of PEGylation with Various Polymer Sizes on Pharmacokinetic Properties, Structure–Properties Relationships of mPEGylated Small Agonists of TGR5 Receptor

 Vanessa Hoguet , Manuel Lasalle , Mathieu Maingot , Geoffroy Dequirez , Rajaa Boulahjar , et al.
Journal of Medicinal Chemistry, 2021, 64 (3), pp.1593-1610. ⟨10.1021/acs.jmedchem.0c01774⟩
Article dans une revue hal-03185533v1
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Liver-specific RORα deletion does not affect the metabolic susceptibility to western style diet feeding

 Antonio Molinaro , Robert Caesar , Laurent L'Homme , Ara Koh , Marcus Ståhlman , et al.
Molecular metabolism, 2019, 23, pp.82-87. ⟨10.1016/j.molmet.2019.02.010⟩
Article dans une revue inserm-02158994v1
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EMBO workshop on immunology and metabolism.

 Bart Staels , David Dombrowicz , Ursula Grohmann
EMBO Reports, 2011, 12 (5), pp.386-8. ⟨10.1038/embor.2011.68⟩
Article dans une revue inserm-00588108v1
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Fibrates, glitazones, and peroxisome proliferator-activated receptors.

 Fanny Lalloyer , Bart Staels
Arteriosclerosis, Thrombosis, and Vascular Biology, 2010, 30 (5), pp.894-9. ⟨10.1161/ATVBAHA.108.179689⟩
Article dans une revue inserm-00475566v1
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Targeting the gut microbiota with inulin-type fructans: preclinical demonstration of a novel approach in the management of endothelial dysfunction

 Emilie Catry , B. Bindels Laure , Anne Muhr Tailleux , Sophie Lestavel , M. Neyrinck Audrey , et al.
Gut, 2018, Gut, 67 (2), pp.271-283. ⟨10.1136/gutjnl-2016-313316⟩
Article dans une revue hal-03251558v1
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A Mathematical Model of the Liver Circadian Clock Linking Feeding and Fasting Cycles to Clock Function

 Aurore Woller , Helene Duez , Bart Staels , Marc Lefranc
Cell Reports, 2016, 17 (4), pp.1087-1097. ⟨10.1016/j.celrep.2016.09.060⟩
Article dans une revue hal-03142705v1
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Hepatic PPARα is critical in the metabolic adaptation to sepsis

 Réjane Paumelle , Joel T Haas , Nathalie Hennuyer , Eric Baugé , Yann Deleye , et al.
Journal of Hepatology, 2019, 70 (5), pp.963-973. ⟨10.1016/j.jhep.2018.12.037⟩
Article dans une revue hal-04358206v1
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Hepatic molecular signatures highlight the sexual dimorphism of Non-Alcoholic SteatoHepatitis (NASH)

 Jimmy Vandel , Julie Dubois-Chevalier , Celine Gheeraert , Bruno Derudas , Violetta Raverdy , et al.
Hepatology, 2020, ⟨10.1002/HEP.31312⟩
Article dans une revue inserm-02617094v1
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Retinoids Issued from Hepatic Stellate Cell Lipid Droplet Loss as Potential Signaling Molecules Orchestrating a Multicellular Liver Injury Response

 Marie Bobowski-Gerard , Francesco Paolo Zummo , Bart Staels , Jérôme Eeckhoute
Cells, 2018, 7 (9), pii: E137. ⟨10.3390/cells7090137⟩
Article dans une revue inserm-02154783v1
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The HDAC inhibitor trichostatin A impairs pancreatic b-cell function through an epigenome-wide reprogramming

 Frédérik Oger , Maeva Moreno , Mehdi Derhourhi , Bryan Thiroux , Lionel Berberian , et al.
2023
Pré-publication, Document de travail hal-04365596v1
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Title: Bile acid alterations in non-alcoholic fatty liver disease, obesity, insulin resistance and type 2 diabetes: what do the human studies tell?

 Oscar Chávez-Talavera , Joël Haas , Guillaume Grzych , Anne Tailleux , Bart Staels
Current Opinion in Lipidology, 2019, 30 (3), pp.244-254. ⟨10.1097/MOL.0000000000000597⟩
Article dans une revue inserm-02302134v1
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Peroxisomal β-oxidation acts as a sensor for intracellular fatty acids and regulates lipolysis

 Lianggong Ding , Wenfei Sun , Miroslav Balaz , Anyuan He , Manuel Klug , et al.
Nature Metabolism, 2021, 3 (12), pp.1648-1661. ⟨10.1038/s42255-021-00489-2⟩
Article dans une revue inserm-03507759v1
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PERSPECTIVES ON THE USE OF SUPER-ENHANCERS AS A DEFINING FEATURE OF CELL/TISSUE- IDENTITY GENES

 Julie Dubois-Chevalier , Vanessa Dubois , Bart Staels , Philippe Lefebvre , Jérôme Eeckhoute
Epigenomics, 2020, 12, pp.715-723
Article dans une revue inserm-02506724v1
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Control of nuclear receptor activities in metabolism by post-translational modifications.

 Wahiba Berrabah , Pierrette Aumercier , Philippe Lefebvre , Bart Staels
FEBS Letters, 2011, 585 (11), pp.1640-50. ⟨10.1016/j.febslet.2011.03.066⟩
Article dans une revue inserm-00587038v1

Statin Induction of Liver Fatty Acid-Binding Protein (L-FABP) Gene Expression Is Peroxisome Proliferator-activated Receptor-α-dependent

 Jean-François Landrier , Charles Thomas , Jacques Grober , Hélène Duez , Frédéric Percevault , et al.
Journal of Biological Chemistry, 2004, 279 (44), pp.45512-45518. ⟨10.1074/jbc.M407461200⟩
Article dans une revue hal-01959211v1

Peroxisome proliferator-activated receptor-α activation as a mechanism of preventive neuroprotection induced by chronic fenofibrate treatment

 Dominique Deplanque , Patrick Gelé , Olivier Pétrault , Isabelle Six , Christophe Furman , et al.
Journal of Neuroscience, 2003, 23 (15), pp.6264-6271. ⟨10.1523/JNEUROSCI.23-15-06264.2003⟩
Article dans une revue hal-00537698v1
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Near-infrared light activatable hydrogels for metformin delivery

 Li Chengnan , Quentin Pagneux , Anna Voronova , Alexandre Barras , Amar Abderrahmani , et al.
Nanoscale, 2019, 11 (34), pp.15810-15820. ⟨10.1039/c9nr02707f⟩
Article dans une revue hal-02368024v1
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The logic of transcriptional regulator recruitment architecture at cis-regulatory modules controlling liver functions

 Julie Dubois , Vanessa Dubois , Hélène Dehondt , Parisa Mazrooei , Claire Mazuy , et al.
Genome Research, 2017, Genome research, 27 (6), pp.985-996. ⟨10.1101/gr.217075.116⟩
Article dans une revue hal-01647846v1
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Peroxisome Proliferator-activated Receptor α (PPARα) Turnover by the Ubiquitin-Proteasome System Controls the Ligand-induced Expression Level of Its Target Genes

 Christophe Blanquart , Olivier Barbier , Jean-Charles Fruchart , Bart Staels , Corine Glineur
Journal of Biological Chemistry, 2002, 277 (40), pp.37254. ⟨10.1074/jbc.M110598200⟩
Article dans une revue inserm-02474752v1
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PPARs in liver physiology

 Alexandre Berthier , Manuel Johanns , Francesco Paolo Zummo , Philippe Lefebvre , Bart Staels
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2021, 1867 (5), pp.166097. ⟨10.1016/j.bbadis.2021.166097⟩
Article dans une revue inserm-03176517v1

Transcription factor TCF7L2 genetic study in the French population: expression in human beta-cells and adipose tissue and strong association with type 2 diabetes.

 Stéphane Cauchi , David Meyre , Christian Dina , Hélène Choquet , Chantal Samson , et al.
Diabetes, 2006, 55 (10), pp.2903-8. ⟨10.2337/db06-0474⟩
Article dans une revue hal-00173852v1

Peroxisome proliferator-activated receptor-α activation protects brain capillary endothelial cells from oxygen-glucose deprivation-induced hyperpermeability in the blood-brain barrier

 Caroline Mysiorek , Maxime Culot , Lucie Dehouck , Bruno Derudas , Bart Staels , et al.
Current Neurovascular Research, 2009, 6 (3), pp.181-193. ⟨10.2174/156720209788970081⟩
Article dans une revue hal-00544019v1
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Visfatin is induced by peroxisome proliferator-activated receptor gamma in human macrophages.

 Thérèse Hèrvée Mayi , Christian Duhem , Corinne Copin , Mohamed Amine Bouhlel , Elena Rigamonti , et al.
FEBS Journal, 2010, 277 (16), pp.3308-20. ⟨10.1111/j.1742-4658.2010.07729.x⟩
Article dans une revue inserm-00515302v1
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Regulation of PPARα by APP in Alzheimer disease impacts the pharmacological modulation of synaptic activity

 Francisco Sáez-Orellana , Thomas Leroy , Floriane Ribeiro , Anna Kreis , Karelle Leroy , et al.
JCI Insight, 2021, ⟨10.1172/jci.insight.150099⟩
Article dans une revue hal-03280763v1
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The nuclear bile acid receptor FXR is a PKA- and FOXA2-sensitive activator of fasting hepatic gluconeogenesis

 Maheul Ploton , Claire Mazuy , Celine Gheeraert , Vanessa Dubois , Alexandre Berthier , et al.
Journal of Hepatology, 2018, 69 (5), pp.1099-1109. ⟨10.1016/j.jhep.2018.06.022⟩
Article dans une revue inserm-02108132v1

The ALGOVUE Clinical Trial: Effects of the Daily Consumption of Eggs Enriched with Lutein and Docosahexaenoic Acid on Plasma Composition and Macular Pigment Optical Density

 Coralie Schnebelen-Berthier , Niyazi Acar , Emilie Simon , Clémentine Thabuis , Anne Bourdillon , et al.
Nutrients, 2021, 13 (10), pp.3347. ⟨10.3390/nu13103347⟩
Article dans une revue hal-04470449v1

Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism

 Audrey Deprince , Nathalie Hennuyer , Sander Kooijman , Amanda Pronk , Eric Baugé , et al.
Hepatology, 2023, 77 (4), pp.1287-1302. ⟨10.1002/hep.32631⟩
Article dans une revue hal-04470474v1
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