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Engraftment of Human Stem Cell Derived Otic Progenitors in the Damaged Cochlea

Alejandra Lopez-Juarez , Hanae Lahlou , Chantal Ripoll , Yves Cazals , Jean Michel Brezun , et al.
Molecular Therapy, 2019, ⟨10.1016/j.ymthe.2019.03.018⟩
Article dans une revue hal-02544441v1

Culture conditions have an impact on the maturation of traceable, transplantable mouse embryonic stem cell-derived otic progenitor cells.

Nesrine Abboud , Arnaud Fontbonne , Isabelle Watabe , Alain Tonetto , Jean Michel Brezun , et al.
Journal of Tissue Engineering and Regenerative Medicine, 2016, ⟨10.1002/term.2163⟩
Article dans une revue hal-01478887v1
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Blocking c-Jun-N-terminal kinase signaling can prevent hearing loss induced by both electrode insertion trauma and neomycin ototoxicity.

Adrien A. Eshraghi , Jing Wang , Eelam Adil , Jiao He , Azel Zine , et al.
Hearing Research, 2007, 226 (1-2), pp.168-77. ⟨10.1016/j.heares.2006.09.008⟩
Article dans une revue inserm-00168116v1
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A human induced pluripotent stem cell-based modular platform to challenge sensorineural hearing loss

Azel Zine , Yassine Messat , Bernd Fritzsch
STEM CELLS, 2021, ⟨10.1002/stem.3346⟩
Article dans une revue hal-03221270v1
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Transcriptome-Wide Analysis Reveals a Role for Extracellular Matrix and Integrin Receptor Genes in Otic Neurosensory Differentiation from Human iPSCs

Lejo Johnson Chacko , Hanae Lahlou , Claudia Steinacher , Said Assou , Yassine Messat , et al.
International Journal of Molecular Sciences, 2021, 22 (19), pp.10849. ⟨10.3390/ijms221910849⟩
Article dans une revue hal-03409973v1

Cochlear stem/progenitor cells from a postnatal cochlea respond to Jagged1 and demonstrate that notch signaling promotes sphere formation and sensory potential.

Etienne Savary , Jean Charles Sabourin , Julien Santo , Jean Philippe Hugnot , Christian Chabbert , et al.
Mech Dev, 2008, 125 (8), pp.674-86. ⟨10.1016/j.mod.2008.05.001⟩
Article dans une revue istex inserm-00349478v1