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Ion Channels as Promising Therapeutic Targets for Melanoma

 Aurélie Chantôme , Marie Potier-Cartereau , Sébastien Roger , Christophe Vandier , Olivier Soriani , et al.
Yohei Tanaka. Breakthroughs in Melanoma Research, InTech, pp.429-460, 2011
Chapitre d'ouvrage inserm-00662370v1

cAMP–PKA inhibition of SK3 channel reduced both Ca2+ entry and cancer cell migration by regulation of SK3–Orai1 complex

 Lucie Clarysse , Maxime Guéguinou , Marie Potier-Cartereau , Grégoire Vandecasteele , Philippe Bougnoux , et al.
Pflügers Archiv European Journal of Physiology, 2014, 466 (10), pp.1921-1932. ⟨10.1007/s00424-013-1435-5⟩
Article dans une revue hal-02372875v1

A Novel Calcium-Mediated EMT Pathway Controlled by Lipids: An Opportunity for Prostate Cancer Adjuvant Therapy

 Sandy Figiel , Fanny Bery , Aurélie Chantôme , Delphine Fontaine , Côme Pasqualin , et al.
Cancers, 2019, 11 (11), pp.1814. ⟨10.3390/cancers11111814⟩
Article dans une revue hal-02460772v1

Alkyl ether lipids, ion channels and lipid raft reorganization in cancer therapy

 Paul-Alain Jaffres , Gajate Consuelo , Ana Bouchet , Hélène Couthon , Aurélie Chantôme , et al.
Pharmacology and Therapeutics, 2016, ⟨10.1016/j.pharmthera.2016.06.003⟩
Article dans une revue inserm-01330970v1

Two Approaches for Automatic Nuclei Cell Counting in Low Resolution Fluorescence Images

 Thierry Brouard , Aurélie Chantôme
J.M. Tavares and R.M. Jorge. Computational Vision and Medical Image Processing: Recent Trends, Springer, pp.311-326, 2011
Chapitre d'ouvrage hal-01067465v1
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Development of pyrene-based fluorescent ether lipid as inhibitor of SK3 ion channels

 Alicia Bauduin , Marion Papin , Aurélie Chantôme , Hélène Couthon , Laure Burel-Deschamps , et al.
European Journal of Medicinal Chemistry, 2021, 209, pp.112894. ⟨10.1016/j.ejmech.2020.112894⟩
Article dans une revue hal-02997273v1
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Lipidic synthetic alkaloids as SK3 channel modulators. Synthesis and biological evaluation of 2-substituted tetrahydropyridine derivatives with potential anti-metastatic activity

 Sana Kouba , Julien Braire , Romain Félix , Aurélie Chantôme , Paul-Alain Jaffres , et al.
European Journal of Medicinal Chemistry, 2020, 186, pp.111854. ⟨10.1016/j.ejmech.2019.111854⟩
Article dans une revue hal-03027843v1

New Disaccharide-Based Ether Lipids as SK3 Ion Channel Inhibitors

 Wilfried Berthe , Charlotte Sevrain , Aurélie Chantôme , Ana Maria Bouchet , Maxime Gueguinou , et al.
ChemMedChem, 2016, 11 (14), pp.1531 - 1539. ⟨10.1002/cmdc.201600147⟩
Article dans une revue istex hal-01474320v1

SK3/TRPC1/Orai1 complex regulates SOCE-dependent colon cancer cell migration: a novel opportunity to modulate anti-EGFR mAb action by the alkyl-lipid Ohmline

 Maxime Guéguinou , Thomas Harnois , David Crottes , Arnaud Uguen , Nadine Déliot , et al.
Oncotarget, 2016, 7, pp.36168-36184. ⟨10.18632/oncotarget.8786⟩
Article dans une revue hal-01539569v1

SK3 Gene Polymorphism Is Associated with Taxane Neurotoxicity and Cell Calcium Homeostasis

 Maxime Gueguinou , Carina Rua , Imane Soubai , Erika Viel , Marie Potier-Cartereau , et al.
Clinical Cancer Research, 2018, 24 (21), pp.5313-5320. ⟨10.1158/1078-0432.CCR-18-0870⟩
Article dans une revue hal-02372720v1

Lipid rafts, KCa/ClCa/Ca2+ channel complexes and EGFR signaling: Novel targets to reduce tumor development by lipids?

 Maxime Guéguinou , Audrey Gambade , Romain Félix , Aurélie Chantôme , Yann Fourbon , et al.
Biochimica et Biophysica Acta:Biomembranes, 2015, 1848 (10), pp.2603-2620. ⟨10.1016/j.bbamem.2014.10.036⟩
Article dans une revue hal-02372867v1

New alkyl-lipid blockers of SK3 channels reduce cancer-cell migration and occurrence of metastasis

 Alban Girault , Jean-Pierre Haelters , Marie Potier-Cartereau , Aurélie Chantôme , Michelle Pinault , et al.
Current Cancer Drug Targets, 2011, 11, pp.1111-1125
Article dans une revue inserm-00662356v1
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Constitutive calcium entry and cancer: updated views and insights.

 Olivier Mignen , Bruno Constantin , Marie Potier-Cartereau , Aubin Penna , Mathieu Gautier , et al.
European Biophysics Journal, 2017, 46 (5), pp.395-413. ⟨10.1007/s00249-017-1216-8⟩
Article dans une revue inserm-01526286v1

The SK3/K(Ca)2.3 potassium channel is a new cellular target for edelfosine.

 Marie Potier-Cartereau , Aurélie Chantôme , Virginie Joulin , Alban Girault , Sébastien Roger , et al.
British Journal of Pharmacology, 2011, 162 (2), pp.464-79. ⟨10.1111/j.1476-5381.2010.01044.x⟩
Article dans une revue inserm-00662360v1

Automatic Nuclei Cell Counting in Low-Resolution Fluorescence Images

 Thierry Brouard , Aurélie Chantôme
II ECCOMAS Thematic Conference on Computational Vision and Medical Image Processing, Oct 2009, Porto, Portugal. pp.83-88
Communication dans un congrès hal-01026411v1

Targeting SKCa Channels in Cancer: Potential New Therapeutic Approaches

 Alban Girault , Jean-Pierre Haelters , Marie Potier-Cartereau , Aurélie Chantôme , Paul-Alain Jaffres , et al.
Current Medicinal Chemistry, 2011, sous presse. ⟨10.2174/092986712798992039⟩
Article dans une revue inserm-00662354v1

DiGalactosyl-Glycero-Ether Lipid: synthetic approaches and evaluation as SK3 channel inhibitor.

 Charlotte Sevrain , Jean-Pierre Haelters , Aurélie Chantôme , Hélène Couthon , Maxime Gueguinou , et al.
Organic & Biomolecular Chemistry, 2013, 11 (27), pp.4479-87. ⟨10.1039/c3ob40634b⟩
Article dans une revue inserm-00848879v1

KCa2.3 channel-dependent hyperpolarization increases melanoma cell motility.

 Aurélie Chantôme , Alban Girault , Marie Potier-Cartereau , Christine Collin , Pascal Vaudin , et al.
Experimental Cell Research, 2009, 315 (20), pp.3620-30. ⟨10.1016/j.yexcr.2009.07.021⟩
Article dans une revue istex inserm-00662365v1

Glyco-phospho-glycero-ether lipid as modulator of SK3 ion channel and SK3-dependent cancer cell migration

 C. Sevrain , Wilfried Berthe , Hélène Couthon , J. P. Haelters , M. Bouchet , et al.
Phosphorus, Sulfur, and Silicon and the Related Elements, 2016, 191 (11-12), pp.1623 - 1624. ⟨10.1080/10426507.2016.1217221⟩
Article dans une revue hal-01539329v1

Singular Interaction between an Antimetastatic Agent and the Lipid Bilayer: The Ohmline Case

 Fernando Herrera , Charlotte M. Sevrain , Paul-Alain Jaffres , Hélène Couthon , Axelle Grélard , et al.
ACS Omega, 2017, 2 (10), pp.6361 - 6370. ⟨10.1021/acsomega.7b00936⟩
Article dans une revue hal-01624549v1

Altered SK3/KCa2.3-mediated migration in adenomatous polyposis coli (Apc) mutated mouse colon epithelial cells.

 Marie Potier-Cartereau , Truong-An Tran , Aurélie Chantôme , Alban Girault , Virginie Joulin , et al.
Biochemical and Biophysical Research Communications, 2010, 397 (1), pp.42-7. ⟨10.1016/j.bbrc.2010.05.046⟩
Article dans une revue istex inserm-00662363v1

Thio-ether functionalized glycolipid amphiphilic compounds reveal a potent activator of SK3 channel with vasorelaxation effect

 Charlotte Sevrain , Delphine Fontaine , Alicia Bauduin , Maxime Guéguinou , Bei Li Zhang , et al.
Organic & Biomolecular Chemistry, 2021, 19 (12), pp.2753-2766. ⟨10.1039/D1OB00021G⟩
Article dans une revue hal-03187829v1
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Potassium and Calcium Channel Complexes as Novel Targets for Cancer Research

 Marie Potier-Cartereau , William Raoul , Günther Weber , Karine Mahéo , Raphaël Rapetti-Mauss , et al.
Reviews of Physiology Biochemistry and Pharmacology, 2020, Epub 2020 - 08 August. ⟨10.1007/112_2020_24⟩
Article dans une revue inserm-02921492v1

A novel calcium-mediated epithelial-to-mesenchymal transition pathway controlled by lipids: an opportunity for prostate cancer adjuvant therapy

 Fanny Bery , Sandy Figiel , A.C Chantôme , D.F Fontaine , Côme Pasqualin , et al.
26th Meeting of the EAU Section of Urological Research: In collaboration with the Society for Basic Urologic Research and the EAU Section of Uropathology, Oct 2019, Porto, Portugal. ⟨10.1016/S1569-9056(19)33306-8⟩
Communication dans un congrès hal-02460840v1

KCa and Ca2+ channels: The complex thought

 Maxime Guéguinou , Aurélie Chantôme , Gaëlle Fromont , Philippe Bougnoux , Christophe Vandier , et al.
Biochimica et Biophysica Acta - Molecular Cell Research, 2014, 1843 (10), pp.2322-2333. ⟨10.1016/j.bbamcr.2014.02.019⟩
Article dans une revue hal-02372872v1

Glyco-Phospho-Glycero Ether Lipids (GPGEL): synthesis and evaluation as small conductance Ca2+-activated K+ channel (SK3) inhibitors

 Charlotte M. Sevrain , Jean-Pierre Haelters , Aurélie Chantôme , Hélène Couthon , Alban Girault , et al.
MedChemComm, 2012, 3 (11), ⟨10.1039/C2MD20207G⟩
Article dans une revue hal-01556890v1

Pivotal Role of the Lipid Raft SK3-Orai1 Complex in Human Cancer Cell Migration and Bone Metastases.

 Aurélie Chantôme , Marie Potier-Cartereau , Lucie Clarysse , Gaëlle Fromont , Séverine Marionneau-Lambot , et al.
Cancer Research, 2013, epub ahead of print. ⟨10.1158/0008-5472.CAN-12-4572⟩
Article dans une revue inserm-00848873v1

The SigmaR1 chaperone drives breast and colorectal cancer cell migration by tuning SK3-dependent Ca2+ homeostasis

 M Gueguinou , D Crottès , A. Chantôme , R Rapetti-Mauss , M. Potier-Cartereau , et al.
Oncogene, 2017, 36 (25), pp.3640-3647. ⟨10.1038/onc.2016.501⟩
Article dans une revue hal-02372859v1
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Ca2+ protein alpha 1D of CaV1.3 regulates intracellular calcium concentration and migration of colon cancer cells through a non-canonical activity

 Yann Fourbon , Maxime Guéguinou , Romain Félix , Bruno Constantin , Arnaud Uguen , et al.
Scientific Reports, 2017, 7 (1), pp.14199. ⟨10.1038/s41598-017-14230-1⟩
Article dans une revue hal-01705171v1
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