Anne Zaparucha

Documents

Affiliations actuelles

21582

Identifiants chercheurs

anne-zaparucha
IdRef : 155946307
0000-0003-2531-4148

Contact

Domaines de recherche

Chimie Sciences du Vivant [q-bio]

Publications

	METHOD FOR PREPARING AMINES FROM ALDEHYDES AND KETONES BY BIOCATALYSIS Carine Vergne-Vaxelaire , Véronique de Berardinis , Anne Zaparucha France, Patent n° : EP3649246A1; US11118200B2. 2018 Brevet hal-04171875v1
	New enzymes and method for preparing hydroxylated L-lysine or L-ornithine and analogs thereof Anne Zaparucha , Véronique De Berardinis , Pierre-Loïc Saaidi , Damien Baud France, Patent n° : WO/2015/078889. 2013 Brevet hal-04171878v1

	Adapting an acyl CoA ligase from Metallosphaera sedula for lactam formation by structure-guided protein engineering Nikolas Capra , Chloé Lelièvre , Océane Touré , Aurélie Fossey-Jouenne , Carine Vergne-Vaxelaire Frontiers in Catalysis, 2024, 4, ⟨10.3389/fctls.2024.1360129⟩ Article dans une revue hal-04489511v1
	Native amine dehydrogenases can catalyze the direct reduction of carbonyl compounds to alcohols in the absence of ammonia Aurélie Fossey-Jouenne , Laurine Ducrot , Ewald Jongkind , Eddy Elisée , Anne Zaparucha Frontiers in Catalysis, 2023, 3, pp.1105948. ⟨10.3389/fctls.2023.1105948⟩ Article dans une revue hal-04178006v1
	Expanding the substrate scope of native amine dehydrogenases through in silico structural exploration and targeted protein engineering Laurine Ducrot , Megan Bennett , Gwenaëlle André-Leroux , Eddy Elisée , Sacha Marynberg ChemCatChem, 2022, 2022, pp.e202200880. ⟨10.1002/cctc.202200880⟩ Article dans une revue cea-03781286v1
	Synthesis of Chiral Amines via a Bi‐Enzymatic Cascade Using an Ene‐Reductase and Amine Dehydrogenase Ewald Jongkind , Aurélie Fossey-Jouenne , Ombeline Mayol , Anne Zaparucha , Carine Vergne-Vaxelaire ChemCatChem, 2022, 14 (2), ⟨10.1002/cctc.202101576⟩ Article dans une revue hal-04177991v1
	Biocatalytic Reductive Amination by Native Amine Dehydrogenases to Access Short Chiral Alkyl Amines and Amino Alcohols Laurine Ducrot , Megan Bennett , Adam Caparco , Julie Champion , Andreas Bommarius Frontiers in Catalysis, 2021, 1, ⟨10.3389/fctls.2021.781284⟩ Article dans une revue hal-04178002v1
	Nitrilase immobilization and transposition from a micro‐scale batch to a continuous process increase the nicotinic acid productivity Chalore Teepakorn , Petra Zajkoska , Gregory Cwicklinski , Véronique de Berardinis , Anne Zaparucha Biotechnology Journal, 2021, 16 (10), pp.2100010. ⟨10.1002/biot.202100010⟩ Article dans une revue hal-03664115v1
	Complete Genome Sequences of Two Pseudomonas Species Isolated from Marine Environments of the Pacific Ocean Shi-Zhen Wang , Corinne Cruaud , Jean-Marc Aury , David Vallenet , Julie Poulain Microbiology Resource Announcements, 2021, 10 (16), ⟨10.1128/mra.01062-19⟩ Article dans une revue hal-04178012v1
	Purification and Characterization of Nitphym, a Robust Thermostable Nitrilase From Paraburkholderia phymatum Thomas Bessonnet , Aline Mariage , Jean-Louis Petit , Virginie Pellouin , Adrien Debard Frontiers in Bioengineering and Biotechnology, 2021, 9, ⟨10.3389/fbioe.2021.686362⟩ Article dans une revue cea-03664095v1
	Metagenomic Mining for Amine Dehydrogenase Discovery Adam Caparco , Eric Pelletier , Jean Louis Petit , Aurélie Jouenne , Bettina Bommarius Advanced Synthesis and Catalysis, 2020, 362 (12), pp.2427-2436. ⟨10.1002/adsc.202000094⟩ Article dans une revue hal-04150129v1
	XszenFHal, a novel tryptophan 5-halogenase from Xenorhabdus szentirmaii Jérémy Domergue , Diane Erdmann , Aurélie Fossey-Jouenne , Jean-Louis Petit , Adrien Debard AMB Express, 2019, 9 (1), pp.175. ⟨10.1186/s13568-019-0898-y⟩ Article dans une revue pasteur-03026562v1
	XszenFHal, a novel tryptophan 5-halogenase from Xenorhabdus szentirmaii Jérémy Domergue , Diane Erdmann , Aurélie Fossey-Jouenne , Jean-Louis Petit , Adrien Debard AMB Express, 2019, 9 (1), pp.175. ⟨10.1186/s13568-019-0898-y⟩ Article dans une revue hal-04166372v1
	A family of native amine dehydrogenases for the asymmetric reductive amination of ketones Ombeline Mayol , Karine Bastard , Lilian Beloti , Amina Frese , Johan P Turkenburg Nature Catalysis, 2019, 2 (4), pp.324-333. ⟨10.1038/s41929-019-0249-z⟩ Article dans une revue hal-02945525v1
	ATP Regeneration System in Chemoenzymatic Amide Bond Formation with Thermophilic CoA Ligase Chloé Lelièvre , Mélanie Balandras , Jean‐louis Petit , Carine Vergne-Vaxelaire , Anne Zaparucha ChemCatChem, 2019, 12 (4), pp.1184-1189. ⟨10.1002/cctc.201901870⟩ Article dans une revue hal-04167114v1
	Characterization of a thermotolerant ROK-type mannofructokinase from Streptococcus mitis: application to the synthesis of phosphorylated sugars Carine Vergne-Vaxelaire , Aline Mariage , Jean-Louis Petit , Aurélie Fossey-Jouenne , Christine Guérard-Hélaine Applied Microbiology and Biotechnology, 2018, 102 (13), pp.5569-5583. ⟨10.1007/s00253-018-9018-1⟩ Article dans une revue hal-02323767v1
	Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family Karine Bastard , Tatiana Isabet , Enrico Stura , Pierre Legrand , Anne Zaparucha Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-018-34795-9⟩ Article dans une revue cea-02099557v1
	Enzymatic cascade reactions for the synthesis of chiral amino alcohols from L-lysine Aurélie Fossey-Jouenne , Carine Vergne-Vaxelaire , Anne Zaparucha Journal of visualized experiments : JoVE, 2018, 132, pp.e56926. ⟨10.3791/56926⟩ Article dans une revue cea-04311404v1
	Biocatalytic Approaches towards the Synthesis of Chiral Amino Alcohols from Lysine: Cascade Reactions Combining alpha-Keto Acid Oxygenase Hydroxylation with Pyridoxal Phosphate- Dependent Decarboxylation Damien Baud , Olivier Peruch , Pierre-Loïc Saaidi , Aurélie Fossey , Aline Mariage Advanced Synthesis & Catalysis, 2017, 359 (9), pp.1563-1569. ⟨10.1002/adsc.201600934⟩ Article dans une revue hal-04167194v1
	Parallel evolution of non-homologous isofunctional enzymes in methionine biosynthesis Karine Bastard , Alain Perret , Aline Mariage , Thomas Bessonnet , Agnès Pinet-Turpault Nature Chemical Biology, 2017, 13, pp.858-866. ⟨10.1038/nchembio.2397⟩ Article dans une revue cea-02132779v1
	Asymmetric reductive amination by a wild-type amine dehydrogenase from the thermophilic bacteria Petrotoga mobilis Ombeline Mayol , Sylvain David , Ekaterina Darii , Adrien Debard , Aline Mariage Catalysis Science & Technology, 2016, 6 (20), pp.7421-7428. ⟨10.1039/C6CY01625A⟩ Article dans une revue hal-04177990v1
	Debromokeramadine from the marine sponge Agelas cf. mauritiana: isolation and short regioselective and flexible synthesis Cosima Schroif-Grégoire , Jérôme Appenzeller , Cécile Debitus , Anne Zaparucha , Ali Al-Mourabit Tetrahedron, 2015, 71 (22), pp.3609-3613. ⟨10.1016/j.tet.2014.12.081⟩ Article dans une revue hal-01152783v1
	Revealing the hidden functional diversity of an enzyme family Karine Bastard , Adam Alexander Thil Smith , Carine Vergne-Vaxelaire , Alain Perret , Anne Zaparucha Nature Chemical Biology, 2014, 10 (1), pp.42-49. ⟨10.1038/nchembio.1387⟩ Article dans une revue hal-02504067v1
	Synthesis of Mono- and Dihydroxylated Amino Acids with New $\alpha$-Ketoglutarate-Dependent Dioxygenases: Biocatalytic Oxidation of C$-$H Bonds Damien Baud , Pierre-Loïc Saaidi , Adam Monfleur , Marine Harari , Julien Cuccaro ChemCatChem, 2014, 6, pp.3012 - 3017. ⟨10.1002/cctc.201402498⟩ Article dans une revue cea-01591870v1
	Large α-aminonitrilase activity screening of nitrilase superfamily members: Access to conversion and enantiospecificity by LC–MS Franck Bordier , Mark Stam , Ekaterina Darii , Sabine Tricot , Aurélie Fossey Journal of Molecular Catalysis B: Enzymatic, 2014, 107, pp.79-88. ⟨10.1016/j.molcatb.2014.05.019⟩ Article dans une revue hal-02504052v1
	Nitrilase Activity Screening on Structurally Diverse Substrates: Providing Biocatalytic Tools for Organic Synthesis Carine Vergne-Vaxelaire , Franck Bordier , Aurélie Fossey , Marielle Besnard-Gonnet , Adrien Debard Advanced Synthesis and Catalysis, 2013, 355 (9), pp.1763-1779. ⟨10.1002/adsc.201201098⟩ Article dans une revue hal-02503873v1
	3-Keto-5-aminohexanoate cleavage enzyme: a common fold for an uncommon Claisen-type condensation Marco Bellinzoni , Karine Bastard , Alain Perret , Anne Zaparucha , Nadia Perchat Journal of Biological Chemistry, 2011, 286 (31), pp.27399-27405. ⟨10.1074/jbc.M111.253260⟩ Article dans une revue pasteur-03137933v1
	Biomimetically inspired short access to the 2-aminoimidazole-fused tetracyclic core of (+/-)-dibromoagelaspongin. Sylvain Picon , Huu Dau Elise Tran , Marie-Thérèse Martin , Pascal Retailleau , Anne Zaparucha Organic Letters, 2009, 11 (12), pp.2523-6. ⟨10.1021/ol900745c⟩ Article dans une revue hal-00432043v1
	A Conserved Gene Cluster Rules Anaerobic Oxidative Degradation of L-Ornithine Nuria Fonknechten , A. Perret , N. Perchat , S. Tricot , C. Lechaplais Journal of Bacteriology, 2009, 191 (9), pp.3162-3167. ⟨10.1128/JB.01777-08⟩ Article dans une revue hal-02503069v1
	N-Pyridinium imidates as new sources of 2-aminoimidazole and imidazoline derivatives S. Picon , A. Zaparucha , A. Al Mourabit Tetrahedron Letters, 2009, 50 (49), pp.6826-6829. ⟨10.1016/j.tetlet.2009.09.101⟩ Article dans une revue hal-00433240v1
	Agelasines J, K, and L from the Solomon Islands Marine Sponge Agelas cf. mauritiana J. Appenzeller , G. Mihci , M. T. Martin , J. F. Gallard , J. L. Menou Journal of Natural Products, 2008, 71 (8), pp.1451-1454. ⟨10.1021/np800212g⟩ Article dans une revue hal-00320681v1
	Debromodispacamides B and D: isolation from the marine sponge Agelas mauritiana and stereoselective synthesis using a biomimetic proline route. Carine Vergne , Jérôme Appenzeller , Céline Ratinaud , Marie-Thérèse Martin , Cécile Debitus Organic Letters, 2008, 10 (3), pp.493-6. ⟨10.1021/ol702866m⟩ Article dans une revue hal-00265603v1
	Preparation of N-alkyl-N′-carboalkoxy guanidines: unexpected effective trans-alkoxylation transforming the 2,2,2-trichloroethoxycarbonyl into various carbamates C. Schroif-Grégoire , K. Barale , A. Zaparucha , A. Al-Mourabit Tetrahedron Letters, 2007, 48 (13), pp.2357-2359. ⟨10.1016/j.tetlet.2007.01.126⟩ Article dans une revue hal-00157575v1
	Direct Access to Marine Pyrrole-2-aminoimidazoles, Oroidin, and Derivatives, via New Acyl-1,2-dihydropyridin Intermediates C. Schroif-Grégoire , N. Travert , A. Zaparucha , A. Al-Mourabit Organic Letters, 2006, 8(14), pp.2961-2964. ⟨10.1021/ol0608451⟩ Article dans une revue hal-00089125v1
	Synthesis of metal complexes of 2,9-bis(2-hydroxyphenyl)-1,10-phenanthroline and their DNA binding and cleaving activities Sylvain Routier , Valérie Joanny , Anne Zaparucha , Herve Vezin , Jean-Pierre Catteau Journal of the Chemical Society, Perkin Transactions 2, 1998, Journal of the Chemical Society, Perkin Transactions 2, pp.863-868. ⟨10.1039/a707941i⟩ Article dans une revue hal-03423348v1

	Hybrid catalysis, assisted by machine learning, for bio-sourced molecules functionalization Antoine Lancien , Guillaume Darlot , Jonathan Bassut , Aurélie Jouenne , Tao Jiang Invited Seminar - University of Graz, Nov 2023, Graz, Austria Communication dans un congrès hal-04336053v1
	Comparison of the biocatalytic performances of immobilized nitrilase in milli-scale reactors for continuous production of nicotinic acid Maïté Michaud , Zoe Anxionnaz-Minvielle , Véronique de Berardinis , Guillaume Nonglaton , Anne Zaparucha BIOTRANS - 16th International Symposium on Biocatalysis & Biotransformations, Jun 2023, La Rochelle, France Communication dans un congrès cea-04431030v1
	Immobilized nitrilase in continuous bioreactors: packed bed reactor vs. milli-structured pillar reactor Maïté Michaud , Carine Vergne-Vaxelaire , Véronique de Berardinis , Anne Zaparucha , Guillaume Nonglaton ECCEECAB 2023 - 14th European Congress of Chemical Engineering and 7th European Congress of Applied Biotechnology, Sep 2023, Berlin, Germany Communication dans un congrès cea-04431029v1
	Expanding the portfolio of enzymes for biocatalysis by extensive biodiversity screening Carine Vergne-Vaxelaire , Eddy Elisée , Laurine Ducrot , Raphael Meheust , Mark Stam 6e Symposium International de l'AFERP, Jul 2023, Orsay - Paris, France Communication dans un congrès hal-04327790v1
	Expanding the portfolio of native Amine Dehydrogenases by extensive biodiversity screening Carine Vergne-Vaxelaire , Eddy Elisée , Laurine Ducrot , Raphael Meheust , Mark Stam BioTrans 2023, Jun 2023, La Rochelle, France Communication dans un congrès hal-04327737v1
	Diverse Amine dehydrogenases for the biocatalytic synthesis of amines Carine Vergne-Vaxelaire , Eddy Elisée , Laurine Ducrot , Ombeline Mayol , Raphael Meheust ENZYNOV'2, Oct 2023, Paris-Romainville, France Communication dans un congrès hal-04327765v1
	Milli-structured bioreactor with immobilized commercial nitrilase for continuous production of nicotinic acid Maïté Michaud , Carine Vergne-Vaxelaire , Véronique de Berardinis , Anne Zaparucha , Guillaume Nonglaton EPIC 8 - 8th European Process Intensification Conference, May 2023, Varsovie, Poland Communication dans un congrès cea-04431033v1
	Hybrid catalysis: towards an optimal combination of catalysts Application to HMF valorization Antoine Lancien , Aurelie Fossey , Robert Wojcieszak , Rénato Froidevaux , Matthias Höhne ISGC 2022, May 2022, La Rochelle, France Communication dans un congrès hal-04158400v1
	CoA ligase for amide and lactam synthesis Touré Océane , Capra Nikolas , Lelièvre Chloé , Fossey Aurélie , Vergne-Vaxelaire Carine CBSO, Jun 2022, Visio conférence, France Communication dans un congrès hal-04405375v1
	Expanding the portfolio of native Amine Dehydrogenases by extensive biodiversity screening Carine Vergne-Vaxelaire , Eddy Elisée , Laurine Ducrot , Raphael Meheust , Mark Stam Amine BioCat 5.0, Nov 2022, Groningen, Netherlands Communication dans un congrès hal-04328280v1
	Metagenomic expansion and active site analysis of the Amine Dehydrogenase family Elisée Eddy , Laurine Ducrot , Raphaël Méheust , Mark Stam , Pelletier Eric International Congress on Biocatalysis 2022, Aug 2022, Hamburg, Germany Communication dans un congrès hal-04360123v1
	Valorisation of bio-based furfurals by hybrid catalysis: towards the synthesis of new amine polymers and surfactants Antoine Lancien , Aurélie Fossey , Robert Wojcieszak , Rénato Froidevaux , Anne Zaparucha CBSO2021, Sep 2021, Cap Ferret, France Communication dans un congrès hal-04303442v1
	Hybrid catalysis: towards an optimal combination of catalysts Application to HMF valorization Antoine Lancien , Aurélie Fossey , Robert Wojcieszak , Rénato Froidevaux , Anne Zaparucha CBSO2021, Sep 2021, Cap Ferret, France Communication dans un congrès hal-04345706v1
	MODAMDH: identification of diverse Amine Dehydrogenases by screening biodiversity using sequence and structure-based approaches Elisée Eddy , Laurine Ducrot , Raphaël Méheust , Karine Bastard , Aurélie Fossey-Jouenne 29th Conference on Intelligent Systems for Molecular Biology (ISMB) - 20th European Conference on Computational Biology (ECCB), Jul 2021, Virtual conference, United States Communication dans un congrès hal-04359840v1
	Expanding the substrate scope of Amine Dehydrogenases by protein engineering Carine Vergne-Vaxelaire , Megan Bennett , Laurine Ducrot , Eddy Elisée , Anne Zaparucha BioTrans 2021, Jul 2021, Graz (virtual conference), Austria Communication dans un congrès hal-04328324v1
	Large scale exploration of the biocatalytic capability of biodiversity for biocatalysis & synthetic biology applications Véronique de Berardinis , Jean-Louis Petit , Carine Vergne-Vaxelaire , David Vallenet , Anne Zaparucha First International symposium on High-Throughput Catalysts Design, Jun 2021, Virtual conference (Lille), France Communication dans un congrès hal-04315412v1
	MODAMDH: identification of diverse Amine Dehydrogenases by screening biodiversity using innovative in silico approaches Eddy Elisée , Raphael Meheust , Laurine Ducrot , Mark Stam , Eric Pelletier International Symposium on High-Throughput Catalyst Design, Jun 2021, Lille (Virtual), France Communication dans un congrès hal-04328578v1
	An overview of the native amine dehydrogenase family : discovery, structural and genomic exploration, protein engineering and biocatalytic applications Carine Vergne-Vaxelaire , Laurine Ducrot , Megan Bennett , Eddy Elisée , Karine Bastard 28e colloque du Club de Biocatalyse en Synthèse Organique, Arkema; Proteus; CBSO, Sep 2021, Lège Cap-Ferret, France Communication dans un congrès hal-04328296v1
	Metagenomic mining for Amine Dehydrogenase discovery Carine Vergne-Vaxelaire , Adam Caparco , Eric Pelletier , Jean-Louis Petit , Aurélie Fossey-Jouenne Amine Biocatalysis 4.0, Feb 2020, Stuttgart, Germany Communication dans un congrès hal-04327878v1
	Exploring biodiversity for biocatalyst discovery: applications to synthetic chemistry and synthetic biology Véronique de Berardinis , Anne Zaparucha , David Vallenet , Carine Vergne , Jean-Louis Petit GMGM Open Scientific day & IPCB Inauguration, May 2019, Strabourg, France Communication dans un congrès hal-04315453v1
	A family of Native Amine Dehydrogenases for the Asymmetric Reductive Amination of Ketones Carine Vergne-Vaxelaire , Ombeline Mayol , Karine Bastard , Lilian Beloti , Amina Frese Novel Enzymes 2018, Technische Universitat Darmstadt, Oct 2018, Damstadt, Germany Communication dans un congrès hal-04328306v1
	Enzymatic cascade synthesis of chiral building-blocks from L-lysine Anne Zaparucha , Raphael Dubois , Olivier Peruch , Damien Baud , Pierre-Loic Saaidi Multiple Enzyme Cascade Processes Congress, Mar 2018, Trondheim ( Norvège), Norway Communication dans un congrès hal-04303639v1
	Enzymatic cascades for the synthesis of amino alcohols Anne Zaparucha , Damien Baud , Olivier Peruch , Pierre-Loic Saaidi , Aurélie Fossey BIOTRANS, Jul 2017, Budapest (Hungary), Hungary Communication dans un congrès hal-04303631v1
	Nouvelle dioxygénases alpha-cetoglutarate dépendantes pour la synthèse de plateformes chirales Anne Zaparucha , Damien Baud , Pierre-Loic Saaidi , Marine Harari , Julien Cuccaro CBSO, Jun 2014, Carry Le Rouet, France Communication dans un congrès hal-04303652v1
	Large nitrilase activity screening on structurally diverse substrates: providing new biocatalytic tools for organic synthesis Anne Zaparucha , Carine Vergne-Vaxelaire , Franck Bordier , Ekaterina Darii , Aurélie Fossey BIOTRANS, Jul 2013, Manchester (UK), United Kingdom Communication dans un congrès hal-04303622v1
	De la biodiversité à la biocatalyse Anne Zaparucha CBSO, Jun 2012, Evry, France Communication dans un congrès hal-04303647v1

	Metagenomic expansion and active site analysis of the Amine Dehydrogenase family Elisée Eddy , Laurine Ducrot , Raphaël Méheust , Mark Stam , Pelletier Eric International Congress on Biocatalysis 2022, Aug 2022, Hamburg, Germany Poster de conférence hal-04360138v1
	One-pot bi-enzymatic cascade with an Old Yellow Enzyme and a native amine dehydrogenase to synthesize chiral amines Ewald Jongkind , Aurélie Fossey-Jouenne , Ombeline Mayol , Anne Zaparucha , Carine Vergne-Vaxelaire BioTrans 2021, Jul 2021, Graz (virtual conference), Austria Poster de conférence hal-04328842v1
	CoA ligase for lactam synthesis Touré Océane , Capra Nikolas , Lelièvre Chloé , Vergne-Vaxelaire Carine , Thunnissen Andy-Mark CBSO, Sep 2021, Cap Ferret, France Poster de conférence hal-04405342v1
	MODAMDH: identification of diverse Amine Dehydrogenases by screening biodiversity using sequence and structure-based approaches Elisée Eddy , Laurine Ducrot , Raphaël Méheust , Karine Bastard , Aurélie Fossey-Jouenne 29th Conference on Intelligent Systems for Molecular Biology (ISMB) - 20th European Conference on Computational Biology (ECCB), Jul 2021, Virtual conference, United States Poster de conférence hal-04359878v1
	MODAMDH: identification of diverse Amine Dehydrogenases by screening biodiversity using sequence and structure-based approaches Elisée Eddy , Laurine Ducrot , Raphaël Méheust , Karine Bastard , Aurélie Fossey-Jouenne BioTrans 2021, Jul 2021, Graz (Virtual Conference), Austria Poster de conférence hal-04360034v1
	Smart ATP regeneration system for chemoenzymatic amide bond formation Chloé M. Lelièvre , Mélanie Balandras , Adrien Debard , Virginie Pellouin , Jean-Louis Petit 14th Biotrans symposium, Jul 2019, Groningen, Netherlands Poster de conférence hal-04354478v1
	Production of valuable hydroxylated-L-lysine by novel α-keto acid dependent oxygenases Selina Seide , Anne Zaparucha , Katrin Rosenthal , Stephan Lütz , Martina Pohl BIOTRANS, Jul 2019, Groningen, Netherlands Poster de conférence hal-04405143v1
	From structural elucidation to active site classification: exploration of an enzyme family Karine Bastard , Tatiana Isabet , Enrico A Stura , Pierre Legrand , Anne Zaparucha BIOTRANS, Jul 2019, Groningen, Netherlands Poster de conférence hal-04405103v1

	Chapter 1. Genome Mining for Enzyme Discovery Anne Zaparucha , Véronique de Berardinis , Carine Vaxelaire-Vergne Modern Biocatalysis, Royal Society of Chemistry, pp.1-27, 2018, Catalysis Series, ⟨10.1039/9781788010450-00001⟩ Chapitre d'ouvrage hal-04150687v1

	Cover Feature: Expanding the Substrate Scope of Native Amine Dehydrogenases through In Silico Structural Exploration and Targeted Protein Engineering (ChemCatChem 22/2022) Laurine Ducrot , Megan Bennett , Gwenaëlle André-Leroux , Eddy Elisée , Sacha Marynberg France. 2022 Image hal-04299738v1

Anne Zaparucha

Domaines de recherche

Publications

METHOD FOR PREPARING AMINES FROM ALDEHYDES AND KETONES BY BIOCATALYSIS

New enzymes and method for preparing hydroxylated L-lysine or L-ornithine and analogs thereof

Adapting an acyl CoA ligase from Metallosphaera sedula for lactam formation by structure-guided protein engineering

Native amine dehydrogenases can catalyze the direct reduction of carbonyl compounds to alcohols in the absence of ammonia

Expanding the substrate scope of native amine dehydrogenases through in silico structural exploration and targeted protein engineering

Synthesis of Chiral Amines via a Bi‐Enzymatic Cascade Using an Ene‐Reductase and Amine Dehydrogenase

Biocatalytic Reductive Amination by Native Amine Dehydrogenases to Access Short Chiral Alkyl Amines and Amino Alcohols

Nitrilase immobilization and transposition from a micro‐scale batch to a continuous process increase the nicotinic acid productivity

Complete Genome Sequences of Two Pseudomonas Species Isolated from Marine Environments of the Pacific Ocean

Purification and Characterization of Nitphym, a Robust Thermostable Nitrilase From Paraburkholderia phymatum

Metagenomic Mining for Amine Dehydrogenase Discovery

XszenFHal, a novel tryptophan 5-halogenase from Xenorhabdus szentirmaii

XszenFHal, a novel tryptophan 5-halogenase from Xenorhabdus szentirmaii

A family of native amine dehydrogenases for the asymmetric reductive amination of ketones

ATP Regeneration System in Chemoenzymatic Amide Bond Formation with Thermophilic CoA Ligase

Characterization of a thermotolerant ROK-type mannofructokinase from Streptococcus mitis: application to the synthesis of phosphorylated sugars

Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family

Enzymatic cascade reactions for the synthesis of chiral amino alcohols from L-lysine

Biocatalytic Approaches towards the Synthesis of Chiral Amino Alcohols from Lysine: Cascade Reactions Combining alpha-Keto Acid Oxygenase Hydroxylation with Pyridoxal Phosphate- Dependent Decarboxylation

Parallel evolution of non-homologous isofunctional enzymes in methionine biosynthesis

Asymmetric reductive amination by a wild-type amine dehydrogenase from the thermophilic bacteria Petrotoga mobilis

Debromokeramadine from the marine sponge Agelas cf. mauritiana: isolation and short regioselective and flexible synthesis

Revealing the hidden functional diversity of an enzyme family

Synthesis of Mono- and Dihydroxylated Amino Acids with New $\alpha$-Ketoglutarate-Dependent Dioxygenases: Biocatalytic Oxidation of C$-$H Bonds

Large α-aminonitrilase activity screening of nitrilase superfamily members: Access to conversion and enantiospecificity by LC–MS

Nitrilase Activity Screening on Structurally Diverse Substrates: Providing Biocatalytic Tools for Organic Synthesis

3-Keto-5-aminohexanoate cleavage enzyme: a common fold for an uncommon Claisen-type condensation

Biomimetically inspired short access to the 2-aminoimidazole-fused tetracyclic core of (+/-)-dibromoagelaspongin.

A Conserved Gene Cluster Rules Anaerobic Oxidative Degradation of L-Ornithine

N-Pyridinium imidates as new sources of 2-aminoimidazole and imidazoline derivatives

Agelasines J, K, and L from the Solomon Islands Marine Sponge Agelas cf. mauritiana

Debromodispacamides B and D: isolation from the marine sponge Agelas mauritiana and stereoselective synthesis using a biomimetic proline route.

Preparation of N-alkyl-N′-carboalkoxy guanidines: unexpected effective trans-alkoxylation transforming the 2,2,2-trichloroethoxycarbonyl into various carbamates

Direct Access to Marine Pyrrole-2-aminoimidazoles, Oroidin, and Derivatives, via New Acyl-1,2-dihydropyridin Intermediates

Synthesis of metal complexes of 2,9-bis(2-hydroxyphenyl)-1,10-phenanthroline and their DNA binding and cleaving activities

Hybrid catalysis, assisted by machine learning, for bio-sourced molecules functionalization

Comparison of the biocatalytic performances of immobilized nitrilase in milli-scale reactors for continuous production of nicotinic acid

Immobilized nitrilase in continuous bioreactors: packed bed reactor vs. milli-structured pillar reactor

Expanding the portfolio of enzymes for biocatalysis by extensive biodiversity screening

Expanding the portfolio of native Amine Dehydrogenases by extensive biodiversity screening

Diverse Amine dehydrogenases for the biocatalytic synthesis of amines

Milli-structured bioreactor with immobilized commercial nitrilase for continuous production of nicotinic acid

Hybrid catalysis: towards an optimal combination of catalysts Application to HMF valorization

CoA ligase for amide and lactam synthesis

Expanding the portfolio of native Amine Dehydrogenases by extensive biodiversity screening

Metagenomic expansion and active site analysis of the Amine Dehydrogenase family

Valorisation of bio-based furfurals by hybrid catalysis: towards the synthesis of new amine polymers and surfactants

Hybrid catalysis: towards an optimal combination of catalysts Application to HMF valorization

MODAMDH: identification of diverse Amine Dehydrogenases by screening biodiversity using sequence and structure-based approaches

Expanding the substrate scope of Amine Dehydrogenases by protein engineering

Large scale exploration of the biocatalytic capability of biodiversity for biocatalysis & synthetic biology applications

MODAMDH: identification of diverse Amine Dehydrogenases by screening biodiversity using innovative in silico approaches

An overview of the native amine dehydrogenase family : discovery, structural and genomic exploration, protein engineering and biocatalytic applications

Metagenomic mining for Amine Dehydrogenase discovery

Exploring biodiversity for biocatalyst discovery: applications to synthetic chemistry and synthetic biology

A family of Native Amine Dehydrogenases for the Asymmetric Reductive Amination of Ketones

Enzymatic cascade synthesis of chiral building-blocks from L-lysine

Enzymatic cascades for the synthesis of amino alcohols

Nouvelle dioxygénases alpha-cetoglutarate dépendantes pour la synthèse de plateformes chirales

Large nitrilase activity screening on structurally diverse substrates: providing new biocatalytic tools for organic synthesis

De la biodiversité à la biocatalyse

Metagenomic expansion and active site analysis of the Amine Dehydrogenase family

One-pot bi-enzymatic cascade with an Old Yellow Enzyme and a native amine dehydrogenase to synthesize chiral amines

CoA ligase for lactam synthesis

MODAMDH: identification of diverse Amine Dehydrogenases by screening biodiversity using sequence and structure-based approaches

MODAMDH: identification of diverse Amine Dehydrogenases by screening biodiversity using sequence and structure-based approaches

Smart ATP regeneration system for chemoenzymatic amide bond formation

Production of valuable hydroxylated-L-lysine by novel α-keto acid dependent oxygenases

From structural elucidation to active site classification: exploration of an enzyme family

Chapter 1. Genome Mining for Enzyme Discovery

Cover Feature: Expanding the Substrate Scope of Native Amine Dehydrogenases through In Silico Structural Exploration and Targeted Protein Engineering (ChemCatChem 22/2022)