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Population Pharmacokinetics of Ibrutinib and Its Dihydrodiol Metabolite in Patients with Lymphoid Malignancies

Fanny Gallais , Loic Ysebaert , Fabien Despas , Sandra de Barros , Loïc Dupré , et al.
Clinical Pharmacokinetics, 2020, 59 (9), pp.1171-1183. ⟨10.1007/s40262-020-00884-0⟩
Article dans une revue hal-02989879v1

Target lysis by human lak cells is critically dependent upon target binding properties, but LFA-1, LFA-3 AND ICAM-1 are not the major adhesion ligands on targets

Anne Quillet-Mary , Laurent Cavarec , Nathalie Kermarrec , Carmen Marchiol-Fournigault , Maria Luisa Gil , et al.
International Journal of Cancer, 1991, 47 (3), pp.473-479. ⟨10.1002/ijc.2910470328⟩
Article dans une revue hal-02349227v1
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Lymphoma Heterogeneity Unraveled by Single-Cell Transcriptomics

Loic Ysebaert , Anne Quillet-Mary , Marie Tosolini , Frederic Pont , Camille Laurent , et al.
Frontiers in Immunology, 2021, 12, pp.597651. ⟨10.3389/fimmu.2021.597651⟩
Article dans une revue hal-03153258v1

Idelalisib improves CD37 antibody BI 836826 cytotoxicity against chemo-resistant /relapse-initiating CLL cells: a rationale for combination treatment

S Betrian , Loic Ysebaert , K Heider , J. P Delord , J Fournié , et al.
Blood Cancer Journal, 2016, 6 (11), pp.e496-e496. ⟨10.1038/bcj.2016.106⟩
Article dans une revue hal-02348641v1

An improved double fluorescence flow cytometry method for the quantification of killer cell/target cell conjugate formation

Laurent Cavarec , Anne Quillet-Mary , Didier Fradelizi , Hélène Conjeaud
Journal of Immunological Methods, 1990, 130 (2), pp.251-261. ⟨10.1016/0022-1759(90)90055-Z⟩
Article dans une revue istex hal-02349237v1

Abstract 2852: Obinutuzumab (GA101) efficacy in chronic lymphocytic leukemia in vitro is not diminished in high risk patients.

Loic Ysebaert , Emilie Laprevotte , Christian Klein , Jean-Jacques Fournié , Anne Quillet-Mary
Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC, Apr 2013, Washington, United States. pp.2852-2852, ⟨10.1158/1538-7445.AM2013-2852⟩
Communication dans un congrès hal-02348799v1

Endogenous IL-8 acts as a CD16 co-activator for natural killer-mediated anti-CD20 B cell depletion in chronic lymphocytic leukemia

Emilie Laprevotte , Loic Ysebaert , Christian Klein , Wilfried Valleron , Amandine Blanc , et al.
Leukemia Research, 2013, 37 (4), pp.440-446. ⟨10.1016/j.leukres.2012.11.015⟩
Article dans une revue istex hal-02348811v1

Oxidative stress-induced activation of Lyn recruits sphingomyelinase and is requisite for its stimulation by Ara-C

Christine Bezombes , Isabelle Plo , Véronique Mansat-de Mas , Anne Quillet-Mary , Anne Nègre-Salvayre , et al.
FASEB Journal, 2001, 15 (9), pp.1583-1585. ⟨10.1096/fj.00-0787fje⟩
Article dans une revue hal-02349143v1
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S141: Eliciting anti-tumor t cell activity in chronic lymphocytic leukemia with bispecific antibody-based combination therapy

Despoina Papazoglou , Loic Ysebaert , Nikolaos Ioannou , Benedetta Apollonio , Piers Patten , et al.
HemaSphere, 2022, 6, pp.42-43. ⟨10.1097/01.hs9.0000843456.05456.f5⟩
Article dans une revue hal-03795600v1

Implication of Mitochondrial Hydrogen Peroxide Generation in Ceramide-induced Apoptosis

Anne Quillet-Mary , Jean-Pierre Jaffrézou , Véronique Mansat , Christine Bordier , Javier Naval , et al.
Journal of Biological Chemistry, 1997, 272 (34), pp.21388-21395. ⟨10.1074/jbc.272.34.21388⟩
Article dans une revue hal-02349177v1

Ibrutinib Exposure and B-Cell Depletion Induced By Anti-CD20 Monoclonal Antibodies Rituximab and Obinutuzumab: Is There a Rationale for Combination Studies?

Loic Ysebaert , Christian Klein , Anne Quillet-Mary
Blood, 2014, 124 (21), pp.1980-1980. ⟨10.1182/blood.V124.21.1980.1980⟩
Article dans une revue hal-02348895v1
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Phased differentiation of γδ T and T CD8 tumor-infiltrating lymphocytes revealed by single-cell transcriptomics of human cancers

Juan-Pablo Cerapio , Marion Perrier , Camille-Charlotte Balança , Pauline Gravelle , Fréderic Pont , et al.
OncoImmunology, 2021, 10 (1), ⟨10.1080/2162402X.2021.1939518⟩
Article dans une revue hal-03363714v1
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Nurse-like cells impact on disease progression in chronic lymphocytic leukemia

F Boissard , C. Laurent , A. Ramsay , A Quillet-Mary , J-J Fournié , et al.
Blood Cancer Journal, 2016, 6 (1), pp.e381-e381. ⟨10.1038/bcj.2015.108⟩
Article dans une revue inserm-02472210v1

B-chronic lymphocytic leukemia chemoresistance involves innate and acquired leukemic side population cells

Emilie Gross , F-E L’faqihi-Olive , Loic Ysebaert , M Brassac , S Struski , et al.
Leukemia, 2010, 24 (11), pp.1885-1892. ⟨10.1038/leu.2010.176⟩
Article dans une revue hal-02348941v1

Immune recovery after fludarabine–cyclophosphamide–rituximab treatment in B-chronic lymphocytic leukemia: implication for maintenance immunotherapy

Loic Ysebaert , Emilie Gross , E Kühlein , A. Blanc , J Corre , et al.
Leukemia, 2010, 24 (7), pp.1310-1316. ⟨10.1038/leu.2010.89⟩
Article dans une revue hal-02348948v1

Protein kinase C-ζ overexpression induces erythroid phenotype in the monocytic leukaemia cell line U937

Véronique Mansat-de Mas , Aurélie de Thonel , Vanessa Gaulin , Cécile Demur , Guy Laurent , et al.
British Journal of Haematology, 2002, 118 (2), pp.646-653. ⟨10.1046/j.1365-2141.2002.03625.x⟩
Article dans une revue hal-03030306v1

Overexpression of Protein Kinase Cζ Confers Protection Against Antileukemic Drugs by Inhibiting the Redox-Dependent Sphingomyelinase Activation

Christine Bezombes , Aurélie de Thonel , Andriana Apostolou , Thierry Louat , Jean-Pierre Jaffrézou , et al.
Molecular Pharmacology, 2002, 62 (6), pp.1446-1455. ⟨10.1124/mol.62.6.1446⟩
Article dans une revue hal-02349104v1

Distribution, function, and prognostic value of cytotoxic T lymphocytes in follicular lymphoma: a 3-D tissue-imaging study

Camille Laurent , Sabina Müller , Catherine Do , Talal Al-Saati , Sophie Allart , et al.
Blood, 2011, 118 (20), pp.5371-5379. ⟨10.1182/blood-2011-04-345777⟩
Article dans une revue hal-02348927v1

TNFα stimulates NKG2D-mediated lytic activity of acute myeloid leukemic cells

F Guilloton , A. de Thonel , C Jean , C. Demur , V Mansat-de Mas , et al.
Leukemia, 2005, 19 (12), pp.2206-2214. ⟨10.1038/sj.leu.2403952⟩
Article dans une revue hal-02349023v1
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Phased differentiation of γδ T and T CD8 tumorinfiltrating lymphocytes revealed by single-cell transcriptomics of human cancers

Juan-Pablo Cerapio , Marion Perrier , Camille-Charlotte Balança , Pauline Gravelle , Fréderic Pont , et al.
OncoImmunology, In press, ⟨10.1080/2162402X.2021.1939518⟩
Article dans une revue hal-03365502v1

Implication of Radical Oxygen Species in Ceramide Generation, c-Jun N-Terminal Kinase Activation and Apoptosis Induced by Daunorubicin

Véronique Mansat-De Mas , Christine Bezombes , Anne Quillet-Mary , Ali Bettaieb , Aurélie de Thonel D’orgeix , et al.
Molecular Pharmacology, 1999, 56 (5), pp.867-874. ⟨10.1124/mol.56.5.867⟩
Article dans une revue hal-02349158v1

Protein kinase C ζ associates with death inducing signaling complex and regulates Fas ligand-induced apoptosis

Ingrid Leroy , Aurélie de Thonel , Guy Laurent , Anne Quillet-Mary
Cellular Signalling, 2005, 17 (9), pp.1149-1157. ⟨10.1016/j.cellsig.2004.12.013⟩
Article dans une revue istex hal-02349056v1
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Longitudinal CITE-Seq profiling of chronic lymphocytic leukemia during ibrutinib treatment: evolution of leukemic and immune cells at relapse

Sarah Cadot , Carine Valle , Marie Tosolini , Frederic Pont , Laetitia Largeaud , et al.
Biomarker Research, 2020, 8 (1), ⟨10.1186/s40364-020-00253-w⟩
Article dans une revue hal-03081383v1

Daunorubicin-induced internucleosomal DNA fragmentation in acute myeloid cell lines.

A Quillet-Mary , V Mansat , E Duchayne , M Come , M Allouche , et al.
Leukemia, 1996, 10 (3), pp.417-25
Article dans une revue hal-02349188v1

Daunorubicin- and Mitoxantrone-Triggered Phosphatidylcholine Hydrolysis: Implication in Drug-Induced Ceramide Generation and Apoptosis

Ali Bettaieb , Isabelle Plo , Véronique Mansat-de Mas , Anne Quillet-Mary , Thierry Levade , et al.
Molecular Pharmacology, 1999, 55 (1), pp.118-125. ⟨10.1124/mol.55.1.118⟩
Article dans une revue hal-02349169v1

DNA polymerase ν gene expression influences fludarabine resistance in chronic lymphocytic leukemia independently of p53 status

Srdana Grgurevic , Patricia Montilla-Perez , Alice Bradbury , Julia Gilhodes , Sophie Queille , et al.
Haematologica, 2018, 103 (6), pp.1038-1046. ⟨10.3324/haematol.2017.174243⟩
Article dans une revue hal-02347541v1

Rituximab inhibits B-cell receptor signaling

Samar Kheirallah , Pierre Caron , Emilie Gross , Anne Quillet-Mary , Justine Bertrand-Michel , et al.
Blood, 2010, 115 (5), pp.985-994. ⟨10.1182/blood-2009-08-237537⟩
Article dans une revue hal-03477044v1
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PKCzeta protects against UV-C-induced apoptosis by inhibiting acid sphingomyelinase-dependent ceramide production

Alexandra Charruyer , Christine Jean , Audrey Colomba , Jean-Pierre Jaffrézou , Anne Quillet-Mary , et al.
Biochemical Journal, 2007, 405 (1), pp.77-83. ⟨10.1042/BJ20061528⟩
Article dans une revue hal-00478682v1

Emerging Concepts for the Treatment of Hematological Malignancies with Therapeutic Monoclonal Antibodies

Aude-Hélène Capietto , Samarh Keirallah , Emilie Gross , Nicolas Dauguet , Emilie Laprevotte , et al.
Current Drug Targets, 2010, 11 (7), pp.790-800. ⟨10.2174/138945010791320845⟩
Article dans une revue hal-02348959v1

Granzyme B induction signalling pathway in acute myeloid leukemia cell lines stimulated by Tumor Necrosis Factor alpha and Fas Ligand

Fabien Guilloton , Christine Jean , Aurélie de Thonel , Guy Laurent , Anne Quillet-Mary
Cellular Signalling, 2007, 19 (6), pp.1132-1140. ⟨10.1016/j.cellsig.2006.12.005⟩
Article dans une revue istex hal-02348993v1