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Antibodies targeting G protein-coupled receptors: Recent advances and therapeutic challenges

Mohammed Akli Ayoub , Pascale Crépieux , Markus Koglin , Marc Parmentier , Jean-Philippe Pin , et al.
Article dans une revue hal-01604272v1

Préliminaire à la construction d’un réseau de signalisation en biologie systémique

Flavie Landomiel , Anubhav Gupta , Denis Maurel , Anne Poupon
Atelier Fouille de Textes - Text Mine, en conjonction avec EGC 2017, Jan 2017, Grenoble, France
Communication dans un congrès hal-01637528v1
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Evolution of genes involved in gamete interaction: Evidence for positive selection, duplications and losses in vertebrates

Camille Meslin , Sylvie Mugnier , Isabelle Callebaut , Michel Laurin , Géraldine Pascal , et al.
PLoS ONE, 2012, 7 (9), pp.1-8. ⟨10.1371/journal.pone.0044548⟩
Article dans une revue hal-01136282v1

Les prédictions du désordre peuvent être utilisées pour prédire les constructions génétiques avec une meilleure expression, solubilité et stabilité

Anne Poupon
Conférences Jacques Monod "Le repliement des protéines dans les maladies infectieuses et neurodégénératives", Apr 2009, Aussois, France. n.p
Communication dans un congrès hal-02816942v1
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Advances in computational modeling approaches of pituitary gonadotropin signaling

Romain Yvinec , Pascale Crépieux , Eric Reiter , Anne Poupon , Frédérique Clément
Expert Opinion on Drug Discovery, 2018, 13 (9), pp.799-813. ⟨10.1080/17460441.2018.1501025⟩
Article dans une revue hal-01913612v1

Mapping the follicle-stimulating hormone-induced signaling networks

Pauline Gloaguen , Pascale Crépieux , Domitille Heitzler , Anne Poupon , Eric Reiter
Frontiers in Endocrinology, 2011, 2 (Article 45), pp.1-13. ⟨10.3389/fendo.2011.00045⟩
Article dans une revue hal-01129612v1

p70S6K and PKA anchorage on a common site on β-arrestin 1 provides clues on the particular activation mode of p70S6K downstream of the FSHR

Astrid Musnier , Flavie Landomiel , Thomas Bourquard , Kelly León , Thomas Boulo , et al.
3. Annual Meeting of the GDR 3545 RCPG-PhysioMed, Oct 2014, Montpellier, France. 2014
Poster de conférence hal-02793005v1

A docking analysis of the statistical physics of protein-protein recognition.

Julie Bernauer , Anne Poupon , Jérôme Azé , Joël Janin
Physical Biology, 2005, 2 (2), pp.S17-23. ⟨10.1088/1478-3975/2/2/S02⟩
Article dans une revue inria-00431699v1

Predicting the 3D structure of macromolecular assemblies using PRIOR

Thomas Bourquard , Flavie Landomiel , Gwenhael Jegot , Jérémy Decourtye , Marie-Christine Maurel , et al.
International Conference on Gonadotropins & Receptors, Sep 2014, Tours, France. , 2014, ICGRIII International Conference on Gonadotropins & Receptors
Poster de conférence hal-02743415v1

Beta-arrestin 2 barcode of phosphorylation: impact on beta-arrestin-dependent signaling

Franck Vandermoere , Elisabeth Cassier , Nathalie Langonné Gallay , Thomas Bourquard , Romain Yvinec , et al.
3. Annual Meeting of the GDR 3545 RCPG-PhysioMed, Oct 2014, Montpellier, France. 2014
Poster de conférence hal-02793437v1
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Biased signaling and allosteric modulation at the FSHR

Flavie Landomiel , Francesco de Pascali , Pauline Raynaud , Frédéric Jean-Alphonse , Romain Yvinec , et al.
Frontiers in Endocrinology, 2019, 10, pp.148. ⟨10.3389/fendo.2019.00148⟩
Article dans une revue hal-02362523v1

G protein-dependent signaling triggers a β-arrestin-scaffolded p70S6K/ rpS6 module that controls 5'TOP mRNA translation in FSH stimulated cells

Aurélie Trefier , Astrid Musnier , Flavie Landomiel , Thomas Bourquard , Thomas Boulo , et al.
1st ICGR-GnRH congress, Sep 2017, Modena, Italy
Communication dans un congrès hal-02736363v1
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Towards a logic-based method to infer provenance-aware molecular networks

Zahira Aslaoui-Errafi , Sarah Cohen-Boulakia , Christine Froidevaux , Pauline Gloaguen , Anne Poupon , et al.
Proc. of the 1st ECML/PKDD International workshop on Learning and Discovery in Symbolic Systems Biology (LDSSB), Sep 2012, Bristol, United Kingdom. pp.103-110
Communication dans un congrès hal-00748041v1

Two Negative Allosteric Modulators (NAMS) display biased activities on FSH-induced β-arrestin recruitment at the FSH-R

Gwenhael Jegot , Anne Poupon , Pascale Crépieux , Nathalie Langonné Gallay , Sonia-Maria Poli , et al.
International Conference on Gonadotropins & Receptors, Sep 2014, Tours, France. , 2014, ICGRIII International Conference on Gonadotropins & Receptors
Poster de conférence hal-02740119v1

Developmental regulation of p70 S6 kinase by a G protein-coupled receptor dynamically modelized in primary cells

Astrid Musnier , Domitille Heitzler , Thomas Boulo , Sophie Tesseraud , Guillaume Durand , et al.
Cellular and Molecular Life Sciences, 2009, 66 (21), pp.3487-3503. ⟨10.1007/s00018-009-0134-z⟩
Article dans une revue istex hal-02660848v1

β-arrestins interact directly to PKA, promoting its translocation to the nucleus and form a transcriptionnally active complex with CREB upon stimulation of Gs-coupled GPCRs

Flavie Landomiel , Thibaud Tranchant , Thomas Bourquard , Nathalie Langonné , Christophe Gauthier , et al.
Molecular Pharmacology Gordon Research Conference - Connecting G protein-coupled receptor mechanisms to physiological functions, Feb 2015, Ventura, United States. 2015, Molecular Pharmacology - Connecting G Protein-Coupled Receptor Mechanisms to Physiological Function
Poster de conférence hal-02744352v1
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Harnessing Fc/FcRn affinity data from patents with different machine learning methods

Christophe Dumet , Martine Pugnière , Corinne Henriquet , Valérie Gouilleux-Gruart , Anne Poupon , et al.
International Journal of Molecular Sciences, 2023, 24 (6), pp.5724. ⟨10.3390/ijms24065724⟩
Article dans une revue hal-04308512v1
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β-arrestin signalling and bias in hormone-responsive GPCRs

Eric Reiter , Mohammed Akli Ayoub , Lucie P. Pellissier , Flavie Landomiel , Astrid Musnier , et al.
Molecular and Cellular Endocrinology, 2017, 449, pp.28-41. ⟨10.1016/j.mce.2017.01.052⟩
Article dans une revue hal-01604784v1
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Assessing gonadotropin receptor function by resonance energy transfer-based assays

Mohammed Akli Ayoub , Flavie Landomiel , Nathalie Langonné , Gwenhael Jegot , Anne Poupon , et al.
Frontiers in Endocrinology, 2015, 6, pp.1-14. ⟨10.3389/fendo.2015.00130⟩
Article dans une revue hal-01422312v1

Intrabody fragments to explore conformation-activity relationships at the FSHR

Pascale Crépieux , Pauline Raynaud , Laëtitia Mathias , Océane Vaugrente , Thomas Boulo , et al.
Targeting GPCR to generate life, preserve the environment and improve animal breeding, Oct 2019, Tours, France
Poster de conférence hal-04180274v1

Analyse des interactions protéine-protéine sur puces et in silico pour la construction rationnelle de peptides interférents.

Thomas Boulo , Thomas Bourquard , Pascale Crépieux , Eric Reiter , Anne Poupon
5. Journées d'Animation Scientifique du département Phase (JAS Phase 2013), Oct 2013, Paris, France. 2013
Poster de conférence hal-02810161v1

p.N680S single nucleotide polymorphism of the FSHR affects FSH-induced β-arrestin recruitment, β-arrestin-dependent translocation of PKA catalytic subunit to the nucleus and CRE-driven transcription

Flavie Landomiel , Thibaud Tranchant , Guillaume Durand , Alfredo Ulloa Aguirre , Pascale Crépieux , et al.
International Conference on Gonadotropins & Receptors, Sep 2014, Tours, France. , 2014, ICGRIII International Conference on Gonadotropins & Receptors
Poster de conférence hal-02739343v1

S680 single nucleotide polymorphism of the FSH receptor increases FSH-induced beta-arrestin recruitment while reducing beta-arrestin-dependent translocation of active PKA to the nucleus

Thibaud Tranchant , Guillaume Durand , Flavie Landomiel , Gwenhael Jegot , Nathalie Gallay , et al.
Gordon Research Conference in Molecular Pharmacology, Apr 2013, Lucca (Barga), Italy. 2013
Poster de conférence hal-02811177v1

Completing signaling networks by abductive reasoning with perturbation experiments

Adrien Rougny , Yoshitaka Yamamoto , Hidetomo Nabeshima , Gauvain Bourgne , Anne Poupon , et al.
25th International Conference on Inductive Logic Programming, Aug 2015, Kyoto, Japan
Communication dans un congrès hal-01259205v1
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The translation regulatory subunit eIF3f controls the kinase-dependent mTOR signaling required for muscle differentiation and hypertrophy in mouse

Alfredo Csibi , Karen Cornille , Marie-Pierre Leibovitch , Anne Poupon , Lionel Tintignac , et al.
PLoS ONE, 2010, 5 (2), pp.e8994. ⟨10.1371/journal.pone.0008994⟩
Article dans une revue hal-01129600v1
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Une nouvelle fonction de score pour l'amarrage protéine-protéine fondée sur les diagrammes de Voronoï

Julie Bernauer , Jérôme Azé , Joël Janin , Anne Poupon
Journées Ouvertes de Biologie Informatique Mathématiques, Jul 2005, Lyon, France
Communication dans un congrès inria-00431703v1
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Characterization of new monoclonal PF4-specific antibodies as useful tools for studies on typical and autoimmune heparin-induced thrombocytopenia

Caroline Vayne , Thi-Huong Nguyen , Jérôme Rollin , Noémie Charuel , Anne Poupon , et al.
Thrombosis and Haemostasis, 2021, 121 (3), pp.322-331. ⟨10.1055/s-0040-1717078⟩
Article dans une revue hal-03039816v1
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TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity

Harshad Ugamraj , Kevin Dang , Laure-Hélène Ouisse , Benjamin Buelow , Eduardo Chini , et al.
Article dans une revue hal-03684683v1

p70S6K and PKA docking on a common site on β-arrestin 1 provides clues on the particular activation mode of p70S6K downstream of the FSH receptor

Astrid Musnier , Flavie Landomiel , Thomas Bourquard , Kelly León , Thomas Boulo , et al.
Molecular Pharmacology Gordon Research Conference - Connecting G protein-coupled receptor mechanisms to physiological functions, Feb 2015, Ventura, United States. 2015, Molecular Pharmacology - Connecting G Protein-Coupled Receptor Mechanisms to Physiological Function
Poster de conférence hal-02739813v1

The translatome of the FSH receptor reveals tha several FSH-responsive signaling effectors are co-translated in primary rat Sertoli cells

Aurélie Trefier , Romain Yvinec , Thomas Bourquard , Kelly Léon-Huaman , Astrid Musnier , et al.
2. Journées du GdR 3606 Repro, Apr 2017, Tours, France. 75 p., 2017, 2èmes Journées Scientifiques du GdR Repro
Poster de conférence hal-01603078v1