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Structural and Binding Studies of the Three-metal Center in Two Mycobacterial PPM Ser/Thr Protein Phosphatases

Annemarie Wehenkel , Marco Bellinzoni , Francis Schaeffer , Andrea Villarino , Pedro M. Alzari
Journal of Molecular Biology, 2007, 374 (4), pp.890-898. ⟨10.1016/j.jmb.2007.09.076⟩
Article dans une revue istex pasteur-03139199v1

Functional Plasticity and Allosteric Regulation of α-Ketoglutarate Decarboxylase in Central Mycobacterial Metabolism

Tristan Wagner , Marco Bellinzoni , Annemarie Wehenkel , Helen M. O'Hare , Pedro M. Alzari
Chemistry & biology, 2011, 18 (8), pp.1011-1020. ⟨10.1016/j.chembiol.2011.06.004⟩
Article dans une revue pasteur-03137931v1

Regulation of glutamate metabolism by protein kinases in mycobacteria

Helen O'Hare , Rosario Durán , Carlos Cerveñansky , Marco Bellinzoni , Anne Marie Wehenkel , et al.
Molecular Microbiology, 2008, 70 (6), pp.1408-1423. ⟨10.1111/j.1365-2958.2008.06489.x⟩
Article dans une revue pasteur-03139167v1

Proteomic Identification of M.tuberculosis Protein Kinase Substrates: PknB Recruits GarA, a FHA Domain-containing Protein, Through Activation Loop-mediated Interactions

A. Villarino , R. Duran , A. Wehenkel , P. Fernandez , Patrick England , et al.
Journal of Molecular Biology, 2005, 350 (5), pp.953-963. ⟨10.1016/j.jmb.2005.05.049⟩
Article dans une revue istex pasteur-03144578v1

Proteome remodeling in the Mycobacterium tuberculosis PknG knockout: Molecular evidence for the role of this kinase in cell envelope biogenesis and hypoxia response

Analía Lima , Alejandro Leyva , Bernardina Rivera , María Magdalena Portela , Magdalena Gil , et al.
Journal of Proteomics, 2021, 244, pp.104276. ⟨10.1016/j.jprot.2021.104276⟩
Article dans une revue pasteur-03256994v1

Structural Insights Into the Catalytic Mechanism of Trypanosoma Cruzi Trans-Sialidase

María Fernanda Amaya , Andrew G Watts , Iben Damager , Annemarie Wehenkel , Tong Nguyen , et al.
Structure, 2004, 12 (5), pp.775 - 784. ⟨10.1016/j.str.2004.02.036⟩
Article dans une revue pasteur-02554101v1

Conserved autophosphorylation pattern in activation loops and juxtamembrane regions of Mycobacterium tuberculosis Ser/Thr protein kinases

Rosario Durán , Andrea Villarino , Marco Bellinzoni , Annemarie Wehenkel , Pablo Fernandez , et al.
Biochemical and Biophysical Research Communications, 2005, 333 (3), pp.858-867. ⟨10.1016/j.bbrc.2005.05.173⟩
Article dans une revue istex pasteur-03144581v1
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Essential dynamic interdependence of FtsZ and SepF for Z-ring and septum formation in Corynebacterium glutamicum

Adrià Sogues , Mariano Martinez , Quentin Gaday , Mathilde Ben Assaya , Martín Graña , et al.
Nature Communications, 2020, 11 (1), pp.1641. ⟨10.1038/s41467-020-15490-8⟩
Article dans une revue pasteur-02559164v1
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FtsEX-independent control of RipA-mediated cell separation in Corynebacteriales

Quentin Gaday , Daniela Megrian , Giacomo Carloni , Mariano Martinez , Bohdana Sokolova , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (50), pp.e2214599119. ⟨10.1073/pnas.2214599119⟩
Article dans une revue pasteur-03914065v1
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Population genomics and antimicrobial resistance in Corynebacterium diphtheriae

Melanie Hennart , Leonardo G. Panunzi , Carla Rodrigues , Quentin Gaday , Sarah L. Baines , et al.
Genome Medicine, 2020, 12 (1), pp.107. ⟨10.1186/s13073-020-00805-7⟩
Article dans une revue pasteur-03199447v1
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The crystal structure of the catalytic domain of the Ser/Thr kinase PknA from M. tuberculosis shows an Src-like autoinhibited conformation

Tristan Wagner , Matthieu Alexandre , Rosario Duran , Nathalie Barilone , Annemarie Wehenkel , et al.
Proteins - Structure, Function and Bioinformatics, 2015, 83 (5), pp.982-988. ⟨10.1002/prot.24754⟩
Article dans une revue istex pasteur-01175001v1
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Bacterial kinesin light chain (Bklc) links the Btub cytoskeleton to membranes

Lurlène Akendengue , Sylvain Trépout , Martín Graña , Alexis Voegele , Carsten Janke , et al.
Scientific Reports, 2017, 7, pp.45668. ⟨10.1038/srep45668⟩
Article dans une revue pasteur-01508066v1
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Structure of the RZZ complex and molecular basis of its interaction with Spindly

Shyamal Mosalaganti , Jenny Keller , Anika Altenfeld , Franz Herzog , Pascaline Rombaut , et al.
Journal of Cell Biology, 2017, 216 (4), pp.961-981. ⟨10.1083/jcb.201611060⟩
Article dans une revue pasteur-02749286v1
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SepF is the FtsZ anchor in archaea, with features of an ancestral cell division system

Nika Pende , Adrià Sogues , Daniela Megrian , Anna Sartori-Rupp , Patrick England , et al.
Nature Communications, 2021, 12 (1), pp.3214. ⟨10.1038/s41467-021-23099-8⟩
Article dans une revue hal-03251652v1

Legionella para-effectors target chromatin and promote bacterial replication

Daniel Schator , Sonia Mondino , Jérémy Berthelet , Cristina Di Silvestre , Mathilde Ben Assaya , et al.
Nature Communications, 2023, 14 (1), pp.2154. ⟨10.1101/2022.10.16.512414⟩
Article dans une revue pasteur-03914071v1
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Mycobacterial Ser/Thr protein kinases and phosphatases: physiological roles and therapeutic potential.

Annemarie Wehenkel , Marco Bellinzoni , Martin Graña , Rosario Duran , Andrea Villarino , et al.
Biochimica et Biophysica Acta - Molecular Cell Research, 2008, 1784 (1), pp.193-202. ⟨10.1016/j.bbapap.2007.08.006⟩
Article dans une revue pasteur-00508942v1
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3D structures of the Plasmodium vivax subtilisin-like drug target SUB1 reveal conformational changes to accommodate a substrate-derived α-ketoamide inhibitor

Mariano Martinez , Fernando A Batista , Manon Maurel , Anthony Bouillon , Laura Ortega Varga , et al.
Acta crystallographica Section D : Structural biology [1993-..], 2023, 79 (8), ⟨10.1107/s2059798323004710⟩
Article dans une revue pasteur-04158872v1
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Novel mechanistic insights into physiological signaling pathways mediated by mycobacterial Ser/Thr protein kinases

Marco Bellinzoni , Anne Marie Wehenkel , Rosario Durán , Pedro Alzari
Microbes and Infection, 2019, 21 (5-6), pp.222-229. ⟨10.1016/j.micinf.2019.06.015⟩
Article dans une revue pasteur-02749197v1
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New substrates and interactors of the mycobacterial Serine/Threonine protein kinase PknG identified by a tailored interactomic approach

Magdalena Gil , Analía Lima , Bernardina Rivera , Jéssica Rossello , Estefanía Urdániz , et al.
Journal of Proteomics, 2019, 192, pp.321-333. ⟨10.1016/j.jprot.2018.09.013⟩
Article dans une revue pasteur-02749223v1

Insights into the Catalytic Mechanism of PPM Ser/Thr Phosphatases from the Atomic Resolution Structures of a Mycobacterial Enzyme

Marco Bellinzoni , Annemarie Wehenkel , William Shepard , Pedro M. Alzari
Structure, 2007, 15 (7), pp.863-872. ⟨10.1016/j.str.2007.06.002⟩
Article dans une revue pasteur-03139223v1
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Eukaryotic-like gephyrin and cognate membrane receptor coordinate corynebacterial cell division and polar elongation

Mariano Martinez , Julienne Petit , Alejandro Leyva , Adrià Sogues , Daniela Megrian , et al.
Nature Microbiology, 2023, 8 (10), pp.1896 - 1910. ⟨10.1038/s41564-023-01473-0⟩
Article dans une revue pasteur-04367080v1
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The FHA-containing protein GarA acts as a phosphorylation-dependent molecular switch in mycobacterial signaling.

Patrick England , Annemarie Wehenkel , Sonia Martins , Sylviane Hoos , Gwenaëlle André-Leroux , et al.
FEBS Letters, 2009, 583 (2), pp.301-7. ⟨10.1016/j.febslet.2008.12.036⟩
Article dans une revue hal-02660100v1

The structure of PknB in complex with mitoxantrone, an ATP-competitive inhibitor, suggests a mode of protein kinase regulation in mycobacteria.

Annemarie Wehenkel , Pablo Fernandez , Marco Bellinzoni , Vincent Catherinot , Nathalie Barilone , et al.
FEBS Letters, 2006, 580 (13), pp.3018-22. ⟨10.1016/j.febslet.2006.04.046⟩
Article dans une revue istex pasteur-03144516v1

The crystal structure of M. leprae ML2640c defines a large family of putative S-adenosylmethionine-dependent methyltransferases in mycobacteria.

Martin Graña , Ahmed Haouz , Alejandro Buschiazzo , Isabelle Miras , Annemarie Wehenkel , et al.
Protein Science, 2007, 16 (9), pp.1896-904. ⟨10.1110/ps.072982707⟩
Article dans une revue pasteur-00508941v1
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A novel nuclease is the executing part of a bacterial plasmid defense system

Manuela Weiß , Giacomo Giacomelli , Mathilde Ben Assaya , Finja Grundt , Ahmed Haouz , et al.
2022
Pré-publication, Document de travail pasteur-03914070v1