Anne Lespine

127

Documents

Publications

	Filarial DAF-12 sense the host serum to resume iL3 development during infection Rémy Bétous , Anthony Emile , Hua Che , Eva Guchen , Didier Concordet PLoS Pathogens, 2023, 19 (6), pp.e1011462. ⟨10.1371/journal.ppat.1011462⟩ Article dans une revue hal-04169441v1
	Genetic polymorphism, constitutive expression and tissue localization of Dirofilaria immitis P-glycoprotein 11: a putative marker of macrocyclic lactone resistance Emily Curry , Roger Prichard , Anne Lespine Parasites & Vectors, 2022, 15 (1), pp.482. ⟨10.1186/s13071-022-05571-6⟩ Article dans une revue hal-04019855v1
	Lack of efficacy of topical administration of eprinomectin against gastrointestinal nematode in a French dairy sheep farm: A case of underexposure of worms Léa Bordes , Denis Ticoulet , Jean-François Sutra , Anne Lespine , Philippe Jacquiet Veterinary Record Case Reports, 2022, 10, pp.e435. ⟨10.1002/vrc2.435⟩ Article dans une revue hal-03832199v1
	A device to simulate contaminant transfer and surface and subsurface flow through intact soil monoliths Nico Hachgenei , Guillaume Nord , Lorenzo Spadini , Henri Mora , François Courvoisier Vadose Zone Journal, 2022, 21 (2), ⟨10.1002/vzj2.20184⟩ Article dans une revue hal-03715127v1
	Effect of sainfoin ( Onobrychis viciifolia ) on cyathostomin eggs excretion, larval development, larval community structure and efficacy of ivermectin treatment in horses Joshua Malsa , Elise Courtot , Michel Boisseau , Bertrand Dumont , Pascale Gombault Parasitology, 2022, 149 (11), pp.1439-1449. ⟨10.1017/S0031182022000853⟩ Article dans une revue hal-03753744v1
	Ivermectin as a potential treatment for COVID-19? Olivier Chosidow , Charlotte Bernigaud , Didier Guillemot , Bruno Giraudeau , Anne Lespine PLoS Neglected Tropical Diseases, 2021, 15 (6), pp.e0009446. ⟨10.1371/journal.pntd.0009446⟩ Article dans une revue hal-03246642v1
	A Large Impact of Obesity on the Disposition of Ivermectin, Moxidectin and Eprinomectin in a Canine Model: Relevance for COVID-19 Patients Alain Bousquet-Mélou , Anne Lespine , Jean-François Sutra , Isabelle Bargues , Pierre-Louis Toutain Frontiers in Pharmacology, 2021, 12, ⟨10.3389/fphar.2021.666348⟩ Article dans une revue hal-03260114v1
	Ivermectin treatment in lactating mares results in suboptimal ivermectin exposure in their suckling foals Ghismon-De-Kasin Mayinda , Delphine Serreau , Amandine Gesbert , Fabrice Reigner , Jean-François Sutra Veterinary Parasitology, 2021, 296, 5 p. ⟨10.1016/j.vetpar.2021.109511⟩ Article dans une revue hal-03282424v1
	Serious Ivermectin Toxicity and Human ABCB1 Nonsense Mutations Eloise Baudou , Anne Lespine , Geneviève Durrieu , François André , Peggy Gandia New England Journal of Medicine, 2020, 383 (8), pp.787--789. ⟨10.1056/NEJMc1917344⟩ Article dans une revue hal-02928174v1
	P-glycoprotein (ABCB1) is involved in vitamin K efflux Marielle Margier , Cedric Le May , Tiffany Antoine , Charlotte Halimi , Marion Nowicki Food Chemistry, 2020, 343, pp.1-5. ⟨10.1016/j.foodchem.2020.128510⟩ Article dans une revue hal-03012693v1
	First report of multiple resistance to eprinomectin and benzimidazole in Haemonchus contortus on a dairy goat farm in France Léa Bordes , Nicolas Dumont , Anne Lespine , Elise Souil , Jean-François Sutra Parasitology International, 2020, 76, pp.102063. ⟨10.1016/j.parint.2020.102063⟩ Article dans une revue hal-03464522v1
	The development of the dog heartworm is highly sensitive to sterols which activate the orthologue of the nuclear receptor DAF‑12. Thavy Long , Mélanie Alberich , François André , Cécile Menez , Roger K Prichard Scientific Reports, 2020, 10 (1), pp.11207. ⟨10.1038/s41598-020-67466-9⟩ Article dans une revue hal-02957764v1
	The transcription factor NHR-8: A new target to increase ivermectin efficacy in nematodes Cécile Ménez , Mélanie Alberich , Elise Courtot , Fabrice Guégnard , Alexandra Blanchard PLoS Pathogens, 2019, 15 (2), 31 p. ⟨10.1371/journal.ppat.1007598⟩ Article dans une revue hal-02628877v1
	ABCB1 (P-glycoprotein) regulates vitamin D absorption and contributes to its transintestinal efflux Marielle Margier , Xavier Collet , Cédric Le May , Charles Desmarchelier , François André FASEB Journal, 2019, 33 (2), pp.2084-2094. ⟨10.1096/fj.201800956R⟩ Article dans une revue hal-01986017v1
	Assessment of the long-acting ivermectin formulation in sheep: Further insight into potential pharmacokinetic interactions Mariana Ballent , Maria Laura Maté , Paula Dominguez , Guillermo Virkel , Mélanie Alberich Journal of Veterinary Pharmacology and Therapeutics, 2019, 42 (2), pp.189-196. ⟨10.1111/jvp.12739⟩ Article dans une revue hal-02618035v1
	Scabies in an obese patient: How should the ivermectin dosing be adapted? G Mellon , L Hermet , Pierre-Louis Toutain , A Dulioust , Anne Lespine Médecine et Maladies Infectieuses, 2019, 49 (4), pp.286-288. ⟨10.1016/j.medmal.2018.09.007⟩ Article dans une revue hal-02618679v1
	Efficacy and pharmacokinetics evaluation of a single oral dose of afoxolaner against Sarcoptes scabiei in the porcine Scabies model for human infestation Charlotte Bernigaud , Fang Fang , Katja Fischer , Anne Lespine , Ludwig S. Aho Antimicrobial Agents and Chemotherapy, 2018, 62 (9), ⟨10.1128/AAC.02334-17⟩ Article dans une revue hal-02627327v1
	Structural model, functional modulation by ivermectin and tissue localization of Haemonchus contortus P-glycoprotein-13 Marion David , Chantal Lebrun , Thomas Duguet , Franck Talmont , Robin Beech International journal for parasitology. Drugs and drug resistance, 2018, 8 (1), pp.145--157. ⟨10.1016/j.ijpddr.2018.02.001⟩ Article dans une revue hal-02177610v1
	P-glycoproteins play a role in ivermectin resistance in cyathostomins L.E. Peachey , G.L. Pinchbeck , J.B. Matthews , F.A. Burden , Anne Lespine International journal for parasitology. Drugs and drug resistance, 2017, 7 (3), pp.388-398. ⟨10.1016/j.ijpddr.2017.10.006⟩ Article dans une revue hal-02620683v1
	Cross-resistance to moxidectin and ivermectin on a meat sheep farm in France Carine Paraud , T. Marcotty , Anne Lespine , Jean-Francois Sutra , I. Pors Veterinary Parasitology, 2016, 226, pp.88-92. ⟨10.1016/j.vetpar.2016.06.033⟩ Article dans une revue hal-02633599v1
	In silico analysis of the binding of anthelmintics to Caenorhabditis elegansP-glycoprotein 1. Marion A. David , Stéphane Orlowski , Roger K. Prichard , Shaima Hashem , François André International journal for parasitology. Drugs and drug resistance, 2016, 6 (3), pp.299-313. ⟨10.1016/j.ijpddr.2016.09.001⟩ Article dans une revue hal-01451654v1
	Preclinical study of single-dose moxidectin, a new oral treatment for scabies: Efficacy, safety, and pharmacokinetics compared to two-Ddose Iiermectin in a porcine model Charlotte Bernigaud , Fang Fang , Katja Fischer , Anne Lespine , Ludwig Serge Aho PLoS Neglected Tropical Diseases, 2016, 10 (10), ⟨10.1371/journal.pntd.0005030⟩ Article dans une revue hal-01608099v1
	Acquired tolerance to ivermectin and moxidectin after drug selection pressure in the nematode Caenorhabditis elegans Cécile Menez , Mélanie Alberich , Dalia Kansoh , Alexandra Blanchard , Anne Lespine Antimicrobial Agents and Chemotherapy, 2016, 60 (8), pp.4809-4819. ⟨10.1128/AAC.00713-16⟩ Article dans une revue hal-02634646v1
	Efficacy of sainfoin (Onobrychis viciifolia) pellets against multi resistant Haemonchus contortus and interaction with oral ivermectin: Implications for on-farm control Elodie Gaudin , Margaux Simon , Jessica Quijada , Francois F. Schelcher , Jean-Francois Sutra Veterinary Parasitology, 2016, 227, pp.122-129. ⟨10.1016/j.vetpar.2016.08.002⟩ Article dans une revue hal-02633792v1
	Kinetics and anthelmintic efficacy of topical eprinomectin when given orally to goats Chloé Badie , Anne Lespine , Jacques Devos , Jean-Francois Sutra , Christophe Chartier Veterinary Parasitology, 2015, 209 (1-2), pp.56-61. ⟨10.1016/j.vetpar.2015.02.013⟩ Article dans une revue hal-02637782v1
	Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions Andrew C. Kotze , Peter W. Hunt , Philip Skuce , Georg von Samson-Himmelstjerna , Richard J. Martin International Journal for Parasitology, 2014, 4 (3), pp.164-184. ⟨10.1016/j.ijpddr.2014.07.007⟩ Article dans une revue hal-02639668v1
	Ivermectin exposure leads to up-regulation of detoxification genes in vitro and in vivo in mice Mélanie Alberich , Cécile Menez , Jean-Francois Sutra , Anne Lespine European Journal of Pharmacology, 2014, 740, pp.428 - 435. ⟨10.1016/j.ejphar.2014.06.052⟩ Article dans une revue hal-02634112v1
	Persistent coma in Strongyloides hyperinfection syndrome associated with persistently increased ivermectin levels David J. van Westerloo , Gijs W. Landman , Roger Prichard , Anne Lespine , Leo G. Visser Clinical Infectious Diseases, 2014, 58 (1), pp.143-144. ⟨10.1093/cid/cit656⟩ Article dans une revue hal-02634358v1
	Lipid-like properties and pharmacology of the anthelmintic macrocyclic lactones Anne Lespine Expert Opinion on Drug Metabolism and Toxicology, 2013, 9 (12), pp.1581-1595. ⟨10.1517/17425255.2013.832200⟩ Article dans une revue hal-02646036v1
	Exposition alimentaire aux pesticides seuls ou en mélange : caractérisation métabolique et impact sur la barrière intestinale Métais Benjamin , Edwin Fouché , Anne Lespine , Anne Galinier , Sutra Jean-François Innovations Agronomiques, 2013, 28, pp.49-57. ⟨10.17180/f0k6-he23⟩ Article dans une revue hal-04537730v1
	Transintestinal Cholesterol Excretion Is an Active Metabolic Process Modulated by PCSK9 and Statin Involving ABCB1 Cedric Le May , Jean Mathieu Berger , Anne Lespine , Bruno Pillot , Xavier Prieur Arteriosclerosis, Thrombosis, and Vascular Biology, 2013, 33 (7), pp.1484-1493. ⟨10.1161/ATVBAHA.112.300263⟩ Article dans une revue hal-03013326v1
	Transintestinal Cholesterol Excretion Is an Active Metabolic Process Modulated by PCSK9 and Statin Involving ABCB1 Cedric Le May , Jean Mathieu Berger , Anne Lespine , Bruno Pillot , Xavier Prieur Arteriosclerosis, Thrombosis, and Vascular Biology, 2013, 33 (7), pp.1484 - 1493. ⟨10.1161/ATVBAHA.112.300263⟩ Article dans une revue hal-02650431v1
	P-glycoproteins and other multidrug resistance transporters in the pharmacology of anthelmintics: Prospects for reversing transport-dependent anthelmintic resistance Roger K. Prichard , Cécile Menez-Berlioz , Anne Lespine International journal for parasitology. Drugs and drug resistance, 2012, 2, pp.58 - 75. ⟨10.1016/j.ijpddr.2011.10.001⟩ Article dans une revue hal-02645017v1
	Characterisation of macrocyclic lactone resistance in two field-derived isolates of Cooperia oncophora Dj Bartley , C.L Mcarthur , L.M Devin , Jean-Francois Sutra , A.A Morrison Veterinary Parasitology, 2012, 190 (3-4), pp.454-460. ⟨10.1016/j.vetpar.2012.07.022⟩ Article dans une revue hal-02652074v1
	Ivermectin induces P-glycoprotein expression and function through mRNA stabilization in murine hepatocyte cell line Cécile Menez-Berlioz , Laila Mselli-Lakhal , Magali Vignault-Foucaud , Patrick Balaguer , Roger Alvinerie Biochemical Pharmacology, 2012, 83 (2), pp.269-278. ⟨10.1016/j.bcp.2011.10.010⟩ Article dans une revue hal-01191347v1
	Moxidectin and the avermectins: Consanguinity but not identity Roger Prichard , Cécile Menez-Berlioz , Anne Lespine International journal for parasitology. Drugs and drug resistance, 2012, 2, pp.134 - 153. ⟨10.1016/j.ijpddr.2012.04.001⟩ Article dans une revue hal-02649069v1
	Endectocides in goats: pharmacology, efficacy and use conditions in the context of anthelmintic resistance Anne Lespine , Christophe Chartier , Herve Hoste , Roger Alvinerie Small Ruminant Research, 2012, 103 (1), pp.10-17. ⟨10.1016/j.smallrumres.2011.10.013⟩ Article dans une revue hal-02651501v1
	Relative Neurotoxicity of Ivermectin and Moxidectin in Mdr1ab (-/-) Mice and Effects on Mammalian GABA(A) Channel Activity Cécile Menez-Berlioz , Jean-Francois Sutra , Roger Prichard , Anne Lespine PLoS Neglected Tropical Diseases, 2012, 6 (11), ⟨10.1371/journal.pntd.0001883⟩ Article dans une revue hal-02644560v1
	Influence of Pluronic 85 and ketoconazole on disposition and efficacy of ivermectin in sheep infected with a multiple resistant Haemonchus contortus isolate Dj Bartley , A.A Morrison , Jacques Dupuy , Y Bartley , Jean-Francois Sutra Veterinary Parasitology, 2012, 187 (3-4), pp.464-472. ⟨10.1016/j.vetpar.2012.02.011⟩ Article dans une revue hal-01222889v1
	P-glycoprotein Dysfunction Contributes to Hepatic Steatosis and Obesity in Mice Magali Vignault-Foucaud , Zeina Soayfane , Cécile Menez-Berlioz , Justine Bertrand-Michel , Pascal Guy PLoS ONE, 2011, 6 (9), ⟨10.1371/journal.pone.0023614⟩ Article dans une revue hal-02650319v1
	P-glycoprotein Dysfunction Contributes to HepaticSteatosis and Obesity in Mice Magali Vignault-Foucaud , Zeina Soayfane , Cécile Menez-Berlioz , Justine Bertrand-Michel , Pascal G.P. Martin PLoS ONE, 2011, 6 (9), pp.e23614 Article dans une revue hal-01137178v1
	Ivermectin Interacts With Human ABCG2 Marton Jani , Ildiko Makai , Emese Kis , Pal Szabo , Tunde Nagy Journal of Pharmaceutical Sciences, 2011, 100 (1), pp.94-97. ⟨10.1002/jps.22262⟩ Article dans une revue hal-02645949v1
	Interaction of anthelmintic drugs with P-glycoprotein in recombinant LLC-PK1-mdr1a cells Jacques Dupuy , Michel Alvinerie , Cécile Menez , Anne Lespine Chemico-Biological Interactions, 2010, 186 (3), pp.280-286. ⟨10.1016/j.cbi.2010.05.013⟩ Article dans une revue hal-02663660v1
	Role of P-Glycoprotein in the Disposition of Macrocyclic Lactones: A Comparison between Ivermectin, Eprinomectin, and Moxidectin in Mice Solange Kiki-Mvouaka , Cécile Menez , Christiane Borin , Faouzi Lyazrhi , Magali Vignault-Foucaud Drug Metabolism and Disposition, 2010, 38 (4), pp.573-580. ⟨10.1124/dmd.109.030700⟩ Article dans une revue hal-02663207v1
	Influence of obesity on the pharmacokinetics of anthelmintic macrocyclic lactones in dogs I Bargues , Anne Lespine , Pierre-Louis Toutain , Alain Bousquet‐mélou Journal of Veterinary Pharmacology and Therapeutics, 2009, 32 (s1), pp.161-162 Article dans une revue hal-02654350v1
	P-glycoprotein interfering agents potentiate ivermectin susceptibility in ivermectin sensitive and resistant isolates of Teladorsagia circumcincta and Haemonchus contortus D.J. Bartley , H. Mcallister , Y. Bartley , Jacques Dupuy , Cécile Menez-Berlioz Parasitology, 2009, 136 (9), pp.1081-1088. ⟨10.1017/S0031182009990345⟩ Article dans une revue hal-02662392v1
	Interaction of macrocyclic lactones with the multidrug transporters: The bases of the pharmacokinetics of lipid-like drugs Anne Lespine , Jacques Dupuy , M Alvinerie , Christine Coméra , T Nagy Current Drug Metabolism, 2009, 10 (3), pp.272-288 Article dans une revue hal-02655821v1
	Pharmacologie et efficacité des endectocides chez les caprins C Chartier , Anne Lespine , Herve Hoste , M.A Alvinerie Bulletin des G.T.V., 2008, 44, pp.119-124 Article dans une revue hal-02654601v1
	Ketoconazole increases the plasma levels of ivermectin in sheep Roger Alvinerie , Jacques Dupuy , Solange Kiki-Mvouaka , Jf Sutra , Anne Lespine Veterinary Parasitology, 2008, 157 (1-2), pp.117-122. ⟨10.1016/j.vetpar.2008.06.017⟩ Article dans une revue hal-02658693v1
	Les endectocides chez les caprins : pharmacologie, efficacité et conditions d'utilisation dans le contexte de la résistance aux anthelminthiques C Chartier , Anne Lespine , Herve Hoste , M Alvinerie Bulletin des G.T.V., 2008, pp.Inconnu Article dans une revue hal-02654687v1
	ABC transporter modulation: a strategy to enhance the activity of macrocyclic lactone anthelmintics Anne Lespine , Roger Alvinerie , Jozef Vercruysse , Roger K. Prichard , Peter Geldhof Trends in Parasitology, 2008, 24 (7), pp.293-298. ⟨10.1016/j.pt.2008.03.011⟩ Article dans une revue hal-02662487v1
	Multiple oral dosing of ketoconazole increases dog exposure to ivermectin C Hugnet , Anne Lespine , Roger Alvinerie Journal of Pharmacy and Pharmaceutical Sciences, 2007, 10 (3), pp.311-318 Article dans une revue hal-02655765v1
	Interaction of macrocyclic lactones with P-glycoprotein : Structure - affinity relationship Eur Anne Lespine , S. Martin , J. Dupuy , A. Roulet , T. Pineau Journal of Pharmaceutical Sciences, 2007, pp.84-94 Article dans une revue hal-00207662v1
	Estimation of absolute oral bioavailability of moxidectin in dogs using a semi-simultaneous method: influence of lipid co-administration. Elodie Lallemand , Anne Lespine , Michel Alvinerie , Alain Bousquet‐mélou , Pierre-Louis Toutain Journal of Veterinary Pharmacology and Therapeutics, 2007, 30 (5), pp.375-80. ⟨10.1111/j.1365-2885.2007.00878.x⟩ Article dans une revue hal-00517557v1
	Interaction of macrocyclic lactones with P-glycoprotein: Structure-affinity relationship Anne Lespine , Sylvie Martin , Jacques Dupuy , Alain Roulet , Thierry Pineau European Journal of Pharmaceutical Sciences, 2007, 30 (1), pp.84-94. ⟨10.1016/j.ejps.2006.10.004⟩ Article dans une revue hal-02668370v1
	Fumagillin, a new P-glycoprotein-interfering agent able to modulate moxidectin efflux in rat hepatocytes Jacques Dupuy , Anne Lespine , Jean-Francois Sutra , Roger Alvinerie Journal of Veterinary Pharmacology and Therapeutics, 2006, 29 (6), pp.489-494 Article dans une revue hal-02655459v1
	Assessment of a liposomal formulation of ivermectin in rabbit after a single subcutaneous administration Mohamad Firas Bassissi , Anne Lespine , Roger Alvinerie Parasitology Research, 2006, 98 (3), pp.244-249. ⟨10.1007/s00436-005-0073-z⟩ Article dans une revue hal-02659880v1
	The interaction between moxidectin and MDR transporters in primary cultures of rat hepatocytes Jacques Dupuy , Anne Lespine , Jf Sutra , M Alvinerie Journal of Veterinary Pharmacology and Therapeutics, 2006, 29 (2), pp.107-111 Article dans une revue hal-02661548v1
	Contribution of lymphatic transport to the systemic exposure of orally administered moxidectin in conscious lymph duct-cannulated dogs. Anne Lespine , Guillaume Chanoit , Alain Bousquet‐mélou , Elodie Lallemand , Firas Mohamad Bassissi European Journal of Pharmaceutical Sciences, 2006, 27 (1), pp.37-43. ⟨10.1016/j.ejps.2005.08.003⟩ Article dans une revue hal-00517563v1
	Interaction of ivermectin with multidrug resistance proteins (MRP1, 2 and 3) Anne Lespine , Jacques Dupuy , S Orlowski , T Nagy , H Glavinas Chemico-Biological Interactions, 2006, 159 (3), pp.169-179. ⟨10.1016/j.cbi.2005.11.002⟩ Article dans une revue hal-02661667v1
	Influence of dyslipidemia on moxidectin distribution in plasma lipoproteins and on its pharmacokinetics Mf Bassissi , Roger Alvinerie , Pgp Martin , B Perret , Anne Lespine Pharmaceutical Research, 2006, 23 (11), pp.2672-2680. ⟨10.1007/s11095-006-9114-2⟩ Article dans une revue hal-02658696v1
	Influence of the route of administration on efficacy and tissue distribution of ivermectin in goat Anne Lespine , M Alvinerie , Jf Sutra , I Pors , C Chartier Veterinary Parasitology, 2005, 128 (3-4), pp.251-260. ⟨10.1016/j.vetpar.2004.11.028⟩ Article dans une revue hal-02683370v1
	Efficacy of eprinomectin pour-on against gastrointestinal nematodes and the nasal bot fly (Oestrus ovis) in sheep Herve Hoste , Anne Lespine , P Lemercier , M Alvinerie , Philippe P. Jacquiet Veterinary Record, 2004, 154 (25), pp.782-785 Article dans une revue hal-02672817v1
	The influence of parasitism on the pharmacokinetics of moxidectin in lambs Anne Lespine , J.F. Sutra , J. Dupuy , M. Alvinerie , Gilles Aumont Parasitology Research, 2004, 93, pp.121-126 Article dans une revue hal-02669260v1
	The influence of parasitism on the pharmacokinetics of moxidectin in lambs Anne Lespine , Jf Sutra , Jacques Dupuy , M Alvinerie , Gilles Aumont Parasitology Research, 2004, 93 (2), pp.121-126. ⟨10.1007/s00436-004-1084-x⟩ Article dans une revue hal-02680452v1
	Macrocyclic lactones: distribution in plasma lipoproteins of several animal species including humans Mf Bassissi , Roger Alvinerie , Anne Lespine Comparative Biochemistry and Physiology - Part C: Toxicology and Pharmacology, 2004, 138 (4), pp.437-444. ⟨10.1016/j.cca.2004.07.011⟩ Article dans une revue hal-02680351v1
	Enhancement of oral moxidectin bioavailability in rabbits by lipid co-administration Mohamad Firas Bassissi , Anne Lespine , Roger Alvinerie Parasitology Research, 2004, 94 (3), pp.188-192. ⟨10.1007/s00436-004-1192-7⟩ Article dans une revue hal-02679907v1
	Efficacy of injectable and pour-on microdose ivermectin in the treatment of goat warble fly infestation by Przhevalskiana silenus (Diptera, Oestridae) A. Giangaspero , M. Alvinerie , D. Traversa , B. Paoletti , Anne Lespine Veterinary Parasitology, 2003, 116, pp.333-343 Article dans une revue hal-02680122v1
	Enhancement of moxidectin bioavailability in lamb by a natural flavonoid: quercetin Jacques Dupuy , G Larrieu , Jf Sutra , Anne Lespine , M Alvinerie Veterinary Parasitology, 2003, 112 (4), pp.337-347. ⟨10.1016/S0304-4017(03)00008-6⟩ Article dans une revue hal-02683396v1
	The comparative serum disposition kinetics of subcutaneous administration of doramectin, ivermectin and moxidectin in the Australian Merino sheep S Barber , V Bowles , Anne Lespine , Roger Alvinerie Journal of Veterinary Pharmacology and Therapeutics, 2003, 26 (5), pp.343-348 Article dans une revue hal-02675599v1
	Pharmacokinetics of ivermectin in the yak (Bos grunniens) Jacques Dupuy , H. Yin , J.X. Luo , D.Y. Yang , G.Q. Guan Veterinary Parasitology, 2003, 117, pp.153-157. ⟨10.1016/j.vetpar.2003.07.025⟩ Article dans une revue hal-02681891v1
	Eprinomectin in goat: assessment of subcutaneous administration Anne Lespine , Jean-Francois Sutra , Jacques Dupuy , Roger Alvinerie Parasitology Research, 2003, 89 (2), pp.120-122. ⟨10.1007/s00436-002-0727-z⟩ Article dans une revue hal-02680249v1

	P-Glycoproteins 6 and 9 role in ivermectin resistance in the nematode model Caenorhabditis elegans Clara Blancfuney , Marie Garcia , Anne Lespine , Mélanie Alberich International Congress of the European Association for Veterinary Pharmacology and Toxicology, Jul 2023, Bruges, Belgium Poster de conférence hal-04166911v1
	Effect of sainfoin (Onobrychis viciifolia) on cyathostomin eggs excretion, larval development, larval community structure and efficacy of ivermectin treatment in horses Joshua Malsa , Elise Courtot , Michel Boisseau , Bertrand Dumont , Pascale Gombault Journées d’Animation Scientifique du Département Santé Animale (JAS SA), Oct 2022, Anglet, France. Poster de conférence hal-03847631v1
	Selected resistance to macrocyclic lactone exhibit modulation of amphid structure and function at genetic level Cécile Menez , Cristina Ballesteros , Ludmel Urdaneta-Marquez , Roger K. Prichard , Anne Lespine Molecular Anthelmintics: from Discovery to Resistance, Feb 2020, santa monica, United States Poster de conférence hal-02958028v1
	Le récepteur nucléaire NRH-8 : une nouvelle cible pour augmenter l’efficacité de l’ivermectine chez les nématodes Cécile Ménez , Mélanie Alberich , Elise Courtot , Sylvie Dervins , Fabrice Guégnard Journées d'Animation Scientifique du Département Santé Animale, Oct 2018, Nantes, France. , 2018, Santé Animale et Santé Publique Poster de conférence hal-02734278v1
	Resistance to macrocyclic lactones: Is there a fitness cost of acquired tolerance to ivermectin and moxidectin in Caenorhabditis elegans? Cécile Menez , Dalia Kansoh , Jean-Francois Sutra , Anne Lespine Molecular Anthelmintics: from Discovery to Resistance, Feb 2016, San Diego, United States Poster de conférence hal-02958055v1
	In vitro comparison of the effect of flavonoids in anthelmintic resistant and susceptible isolates of Haemonchus contortus: preliminary results Guillaume Salle Sallé , Cédric Neveu , Herve Hoste , Anne Lespine BSP Bristol 2013, Apr 2013, Bristol, United Kingdom. 156 p., 2013 Poster de conférence hal-02746557v1
	Médicaments antiparasitaires et ABC transporteurs Solange Kiki-Mvouaka , M Alvinerie , Anne Lespine Journées d’Animation Scientifique du Département Santé Animale, 2009, Port d'Albret, France. pp.Inconnu, 2009 Poster de conférence hal-02814455v1
	Modulation des ABC transporteurs par les lactones macrocycliques : implication des récepteurs nucléaires ? Cécile Menez-Berlioz , Laila Mselli-Lakhal , M Alvinerie , Anne Lespine Journées d’Animation Scientifique du Département Santé Animale, 2009, Port d'Albret, France. pp.Inconnu, 2009 Poster de conférence hal-02815467v1
	Interaction of the anthelmintic ivermectin with breast-cancer resistant protein (BCRP) Anne Lespine , E Kis , T Nagy , Jacques Dupuy , S Orlowski FEBS-ABC2008 Meeting, 2008, Innsbruck, Austria. pp.Inconnu, 2008 Poster de conférence hal-02818058v1
	P-gp interfering agents potentiate ivermectin susceptibility in nematode ivermectin-resistant strains Anne Lespine , D Bartley , Jacques Dupuy , M Alvinerie , Frank Jackson 21st International Conference of the World Association for the Advancement of Veterinary Parasitology (WAAVP), 2007, Ghent, Belgium. pp.Inconnu, 2007 Poster de conférence hal-02816515v1
	Differences between ivermectin and moxidectin related to their affinities for multidrug resistance proteins (MRP1, 2 and 3) Anne Lespine , Jacques Dupuy , Peter Krajcsi , M Alvinerie International Society of the Study of Xenobiotics, 2006, Manchester, United Kingdom. pp.Inconnu, 2006 Poster de conférence hal-02816155v1
	Role of he P-glycoprotein in the cellular efflux of the mocrcyclic lactones (MLs) Influence of interfering agents Anne Lespine , J Dupuis , Alain Roulet , Thierry Pineau , M Alvinerie EU-FEBS Conference, 2004, Copenhagen, Denmark. pp.Inconnu, 2004 Poster de conférence hal-02828610v1
	Putative prediction of macrocyclic lactones in vivo-disposition using an original pharmacological parameter (Vp50) obtained from transport experiments in P-glycoprotein-expressing cells Alain Roulet , Alain Bousquet‐mélou , Didier Concordet , Jacques Dupuy , Anne Lespine 19th International Conference of the World Association for the Advancement of Veterinary Parasitology, 2003, New Orleans, United States. pp.Inconnu, 2003 Poster de conférence hal-02829746v1

	O75 \| Pharmacodynamic and phenotypic evaluation of eprinomectin resistant Haemonchus isolates from French dairy sheep farms Anne Lespine , Sophie Jouffroy , J. Petterman , Marie Garcia , Christelle Grisez 15th International Congress of the European Association for Veterinary Pharmacology and Toxicology, European Association of Veterinary Pharmacology and Toxicology (EAVPT), Jul 2023, Bruges, Belgium. pp.65-65, ⟨10.1111/jvp.13241⟩ Communication dans un congrès hal-04181004v1
	Anthelmintic Fluorescent drugs, new probes to detect anthelmintic resistance in the nematode Caenorhabditis elegans Mélanie Alberich , Jean-Francois Sutra , Marlène Z Lacroix , Anne Lespine WAAVPT 2021, Jul 2021, Dublin (Online), France Communication dans un congrès hal-04169554v1
	The transcription factor NHR-8 is involved in ivermectin tolerance in the model nematode Caenorhabditis elegans and in the strongylid nematode Haemonchus contortus Cécile Menez , Mélanie Alberich , Elise Courtot , Alexandra Blanchard , Hugo Aguilaniu anthelmintics: Discovery to resistance, Jan 2018, Clearwater, United States Communication dans un congrès hal-02929481v1
	The transcription factor NHR-8 is involved in ivermectin tolerance in the model nematode Caenorhabditis elegans and in the strongylid nematode Haemonchus contortus Cécile Ménez , Mélanie Alberich , Elise Courtot , Anne Lespine 26. International Conference of the World Association for the Advancement of Veterinary Parasitology (WAAVP 2017), The Malaysian Society of Parasitology & Tropical Medicine (MSPTM)., Sep 2017, Kuala Lumpur, Malaysia Communication dans un congrès hal-02736808v1
	Discovery of a new factor involved in ivermectin tolerance in the model nematode Caenorhabditis elegans and in the strongylid nematode Haemonchus contortus. Cécile Menez , Mélanie Alberich , Elise Courtot , Anne Lespine Molecular Helminthology: An Integrated Approach, Mar 2017, Cap Cod, United States Communication dans un congrès hal-02957851v1
	ABCB1 is involved in vitamin D intestinal efflux Marielle Margier , Charles Desmarchelier , Alice Bluteau , André Collet , Patrick Borel 16. Fat Soluble Vitamins (FSV) congress, Société Française des Vitamines et Biofacteurs (SFVB). FRA., Mar 2017, Paris, France. 130 p Communication dans un congrès hal-01517923v1
	Comparison of ivermectin and moxidectin resistance profiles in the nematode Caenorhabditis elegans Cécile Menez , Dalia Kansoh , Jean-Francois Sutra , Anne Lespine International Conference of the World Association for the Advancement of Veterinary Parasitology (WAAVP 2015), Aug 2015, liverpool, United Kingdom Communication dans un congrès hal-02929510v1
	Comparative pharmacodynamics and pharmacokinetics of moxidectin and ivermectin endectocides: a brief update R. K. Prichard , Anne Lespine , Cécile Menez 12. International Congress of the European Association for Veterinary Pharmacology and Toxicology (EAVPT 2012), Jul 2012, Noordwijkerhout, Netherlands. 182 p Communication dans un congrès hal-02748125v1
	Chronic administration of ivermectin leads to a decrease of its concentration in the host Mélanie Alberich , Cécile Menez , Anne Lespine 12. International Congress of the European Association for Veterinary Pharmacology and Toxicology (EAVPT 2012), Jul 2012, Noordwijkerhout, Netherlands. 182 p Communication dans un congrès hal-02748957v1
	Differential neurotoxicity of ivermectin and moxidectin in mammals Cécile Menez , Jean-Francois Sutra , R. K. Prichard , Anne Lespine 12. International Congress of the European Association for Veterinary Pharmacology and Toxicology (EAVPT 2012), Jul 2012, Noordwijkerhout, Netherlands. 182 p Communication dans un congrès hal-02748121v1
	Optimizing anthelmintic combinations to counter anthelmintic resistance Anne Lespine Conference of the World Association for the Advancement of Veterinary Parasitology, Saisissez le nom du laboratoire, du service ou du département., Ville service., Aug 2011, Buenos Aires, Argentina Communication dans un congrès hal-02802149v1
	Interaction of anthelminthics with ABC transporters Anne Lespine Symposium on Membrane Ion Channels in Helminth Parasites, Resistance and Site of Action for Anthelmintics, Saisissez le nom du laboratoire, du service ou du département., Ville service., Dec 2011 Communication dans un congrès hal-02803051v1
	Pharmacocinétique de l'éprinomectine chez les souris déficientes en P-gp : comparaison avec l'ivermectine et la moxidectine Solange Kiki-Mvouaka , Christiane Borin , Magali Vignault-Foucaud , Cécile Menez , Christine Coméra Journées d’Animation Scientifique du Département Santé Animale, 2009, Port d'Albret, France. pp.Inconnu Communication dans un congrès hal-02822598v1
	WP6 - Control of P-glycoprotein (Pgp) in both host and parasites for an improvement of anthelmintic treatment. Dominique Kerboeuf , Fabrice Guégnard , Christine Koch , Yves Le Vern , Roger Alvinerie PARASOL - Sixth framework programme of the E.U. (Project FOOD-CT-2005-022851) - Novel solutions for the sustainable control of nematodes in ruminants, 2009, Edinburgh, United Kingdom. n.p Communication dans un congrès hal-02823130v1
	Influence of obesity on the pharmacokinetics of anthelmintic macrocyclic lactones in dogs I Bargues , Anne Lespine , Pierre-Louis Toutain , Alain Bousquet‐mélou 11th International congress of the European Association for Veterinary Pharmacology and Toxicology, 2009, Leipzig, Germany Communication dans un congrès hal-02752015v1
	The anthelmintic ivermectin: a substrate of Breast-Cancer Resistant Protein (BCRP) E Kis , Sylvaine Lecoeur , Cécile Menez , T Nagy , Jacques Dupuy 22nd World Association for the Advancement of Veterinary Parasitology Conference - WAAVP 2009, 2009, Calgary, Canada. pp.Inconnu Communication dans un congrès hal-02821732v1
	Disposition of eprinomectin in P-gp deficient mice: a comparison with ivermectin and moxidectin Solange Kiki-Mvouaka , Christiane Borin , Magali Vignault , Cécile Menez , Christine Coméra 22nd World Association for the Advancement of Veterinary Parasitology Conference - WAAVP 2009, 2009, Calgary, Canada. pp.Inconnu Communication dans un congrès hal-02815515v1
	Investigations into the effects of p-glycoprotein and/or cytochrom P450 inhibitors on the phenotype responses of various developmental stages of ovine nematodes Dj Bartley , Anne Lespine , Jacques Dupuy , M Alvinerie , H Mc Allister 21st International Conference of the World Association for the Advancement of Veterinary Parasitology (WAAVP), 2007, Ghent, Belgium. pp.Inconnu Communication dans un congrès hal-02814112v1
	Interaction of macrocyclic lactones (MLs) with multidrug resistance transporters Anne Lespine , M Alvinerie 21st International Conference of the World Association for the Advancement of Veterinary Parasitology (WAAVP), 2007, Ghent, Belgium. pp.Inconnu Communication dans un congrès hal-02815063v1
	Interaction of MLs with ABC transporters Anne Lespine Invited by SOLVO Biotechnology, 2006, Budapest, Hungary. pp.Inconnu Communication dans un congrès hal-02811791v1
	The role of drug transporters in the disposition of milbemycins and avermectins M Alvinerie , Anne Lespine EAVPT, 2006, Turin, Italy. pp.Inconnu Communication dans un congrès hal-02815213v1
	Influence of anthelmintic drugs on P-glycoprotein transport activity in mdr1-LLC-PK1 cells Jacques Dupuy , Anne Lespine , M Alvinerie EAVPT, 2006, Turin, Italy. pp.Inconnu Communication dans un congrès hal-02812336v1
	Rôle des ABC transporteurs dans le devenir des lactones macrocycliques dans l'organisme Anne Lespine Journées francophones sur les transporteurs ABC, 2006, Paris, France. pp.Inconnu Communication dans un congrès hal-02811820v1
	Differences between ivermectin and moxidectin related to their affinities for multidrug resistance proteins (MRP1, 2 and 3) Anne Lespine , Jacques Dupuy , T Nagy , Peter Krajcsi , M Alvinerie 10e Congrès international de l’EAVPT, 2006, Turin, Italy. pp.Inconnu Communication dans un congrès hal-02816593v1
	Differences between ivermectin and moxidectin related to their affinities for multidrug resistance proteins (MRP1, 2, and 3) Anne Lespine , Jacques Dupuy , Peter Krajcsi , M Alvinerie Inconnu, 2006, pp.Inconnu Communication dans un congrès hal-02814340v1
	Intestinal lymphatic transport of moxidectin in conscious lymph duct-cannulated dogs Anne Lespine , G Chanoit , Alain Bousquet‐mélou , Elodie Lallemand , F Bassissi EUFEPS Conferences 3rd World Conference on Drug Absorption Transport and delivery, 2004, Barcelona, Spain. pp.Inconnu Communication dans un congrès hal-02827582v1
	Effect of route of administration and formulation on ivermectin bioavailability in Chinese cattle M Alvinerie , Anne Lespine , Jacques Dupuy INCO Project nICA42000-30036 meeting, 2004, Shangai, China. pp.Inconnu Communication dans un congrès hal-02825390v1
	Chemotherapy improvement for hypodermosis M Alvinerie , Anne Lespine , Jacques Dupuy INCO Project nICA42000-30036 meeting, 2004, Shangai, China. pp.Inconnu Communication dans un congrès hal-02825185v1
	Influence of hypercholesterolemia on disposition of moxidectin in a rabbit model F Bassissi , M Alvinerie , Anne Lespine EUFEPS Conferences 3rd World Conference on Drug Absorption Transport and delivery, 2004, Barcelona, Spain. pp.Inconnu Communication dans un congrès hal-02827470v1
	Influence of the macrocyclic lactones on the P-glycoprotein function on P-gp overexpressing cells Anne Lespine , Jacques Dupuy , Alain Roulet , Thierry Pineau European Federation for Pharmaceutical Sciences Conference, 2004, Copenhagen, Denmark. pp.Inconnu Communication dans un congrès hal-02830010v1
	Hypodermosis control : determination of dose and route of administration of ivermectin microdosis to goat M Alvinerie , Anne Lespine , Jacques Dupuy INCO Project nICA42000-30036 meeting, 2004, Shangai, China. pp.Inconnu Communication dans un congrès hal-02825675v1
	Eprinomectin in dairy goats : assessment of an optimal dosage Anne Lespine , J Duupuy , Jf Sutra , M Alvinerie , C Chartier 8th International Conference on Goats, 2004, Pretoria, South Africa. pp.Inconnu Communication dans un congrès hal-02825263v1
	Improvement of ML's treatment by control of P-glycoprotein in the host M Alvinerie , Anne Lespine COST - B16, 2004, Paris, France. pp.Inconnu Communication dans un congrès hal-02825235v1
	Use of reversing agents of P-glycoprotein to increase the systematic availability of macrocyclic lactones : a promising tool M Alvinerie , Jacques Dupuy , Jf Sutra , Anne Lespine 19th International Conference of the World Association for the Advancement of Veterinary Parasitology, 2003, New Orleans, United States. pp.Inconnu Communication dans un congrès hal-02825262v1
	Role of the P-glycoprotein in the cellular eflux of macrocyclic lactones : influence of interfering agents Anne Lespine , Alain Roulet , Jacques Dupuy , Thierry Pineau , M Alvinerie 9th EAVPT Congress, 2003, Lisbon, Portugal. pp.Inconnu Communication dans un congrès hal-02828145v1
	Binding of ivermectin and moxidectin to the plasma lipoproteins Anne Lespine , F Bree , F Bassissi , Jf Sutra , Jp Tillement 9th EAVPT Congress, 2003, Lisbon, Portugal. pp.Inconnu Communication dans un congrès hal-02828011v1
	Putative prediction of macrocyclic lactones in vivo-disposition using an original pharmacological parameter [Vp50] obtained from transport experiments in P-glycoprotein-expressing cells Alain Roulet , Alain Bousquet‐mélou , Didier Concordet , Jacques Dupuy , Anne Lespine 19th International Conference of the World Association for the Advancement of Veterinary Parasitology (WAAVP), 2003, New Orleans, United States. pp.Inconnu Communication dans un congrès hal-02829726v1

	Ecotoxicity of antiparasitics: optimization of the use of pharmaceutical forms of ivermectin and its analogues Michel Alvinerie , Pierre-Louis Toutain , Jean-François Sutra , Anne Lespine , Etienne Zundel [Rapport de recherche] ASI0001393, INRAE. 2021, pp.20 Rapport hal-03294640v1
	Le contrôle du varron par l'ivermectine : éradication de l’hypodermose bovine Chantal Boulard , Michel Alvinerie , Pierre‐louis Toutain , Anne Lespine , Etienne Zundel [Rapport de recherche] 1396, INRAE. 2021, pp.17 Rapport hal-03292187v1
	Création de tomates de qualité pour le frais et l’industrie : F1 GARANCE et F1 TERRADOU Rene Damidaux , Anne Lespine , . Asirpa (analyse Socio‐économique Des Impacts de La Recherche Publique Agronomique) , . Département Bap [Rapport Technique] INRA. 2015 Rapport hal-02794423v1

	Antiparasitaires : homme et animal, même combat ! Anne Lespine 2020 Autre publication scientifique hal-02952479v1
	Deux mutations rares chez l'homme responsables de la toxicité du traitement contre la gâle Anne Lespine 2020 Autre publication scientifique hal-02952475v1

Anne Lespine

Publications

Filarial DAF-12 sense the host serum to resume iL3 development during infection

Genetic polymorphism, constitutive expression and tissue localization of Dirofilaria immitis P-glycoprotein 11: a putative marker of macrocyclic lactone resistance

Lack of efficacy of topical administration of eprinomectin against gastrointestinal nematode in a French dairy sheep farm: A case of underexposure of worms

A device to simulate contaminant transfer and surface and subsurface flow through intact soil monoliths

Effect of sainfoin ( Onobrychis viciifolia ) on cyathostomin eggs excretion, larval development, larval community structure and efficacy of ivermectin treatment in horses

Ivermectin as a potential treatment for COVID-19?

A Large Impact of Obesity on the Disposition of Ivermectin, Moxidectin and Eprinomectin in a Canine Model: Relevance for COVID-19 Patients

Ivermectin treatment in lactating mares results in suboptimal ivermectin exposure in their suckling foals

Serious Ivermectin Toxicity and Human ABCB1 Nonsense Mutations

P-glycoprotein (ABCB1) is involved in vitamin K efflux

First report of multiple resistance to eprinomectin and benzimidazole in Haemonchus contortus on a dairy goat farm in France

The development of the dog heartworm is highly sensitive to sterols which activate the orthologue of the nuclear receptor DAF‑12.

The transcription factor NHR-8: A new target to increase ivermectin efficacy in nematodes

ABCB1 (P-glycoprotein) regulates vitamin D absorption and contributes to its transintestinal efflux

Assessment of the long-acting ivermectin formulation in sheep: Further insight into potential pharmacokinetic interactions

Scabies in an obese patient: How should the ivermectin dosing be adapted?

Efficacy and pharmacokinetics evaluation of a single oral dose of afoxolaner against Sarcoptes scabiei in the porcine Scabies model for human infestation

Structural model, functional modulation by ivermectin and tissue localization of Haemonchus contortus P-glycoprotein-13

P-glycoproteins play a role in ivermectin resistance in cyathostomins

Cross-resistance to moxidectin and ivermectin on a meat sheep farm in France

In silico analysis of the binding of anthelmintics to Caenorhabditis elegansP-glycoprotein 1.

Preclinical study of single-dose moxidectin, a new oral treatment for scabies: Efficacy, safety, and pharmacokinetics compared to two-Ddose Iiermectin in a porcine model

Acquired tolerance to ivermectin and moxidectin after drug selection pressure in the nematode Caenorhabditis elegans

Efficacy of sainfoin (Onobrychis viciifolia) pellets against multi resistant Haemonchus contortus and interaction with oral ivermectin: Implications for on-farm control

Kinetics and anthelmintic efficacy of topical eprinomectin when given orally to goats

Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions

Ivermectin exposure leads to up-regulation of detoxification genes in vitro and in vivo in mice

Persistent coma in Strongyloides hyperinfection syndrome associated with persistently increased ivermectin levels

Lipid-like properties and pharmacology of the anthelmintic macrocyclic lactones

Exposition alimentaire aux pesticides seuls ou en mélange : caractérisation métabolique et impact sur la barrière intestinale

Transintestinal Cholesterol Excretion Is an Active Metabolic Process Modulated by PCSK9 and Statin Involving ABCB1

Transintestinal Cholesterol Excretion Is an Active Metabolic Process Modulated by PCSK9 and Statin Involving ABCB1

P-glycoproteins and other multidrug resistance transporters in the pharmacology of anthelmintics: Prospects for reversing transport-dependent anthelmintic resistance

Characterisation of macrocyclic lactone resistance in two field-derived isolates of Cooperia oncophora

Ivermectin induces P-glycoprotein expression and function through mRNA stabilization in murine hepatocyte cell line

Moxidectin and the avermectins: Consanguinity but not identity

Endectocides in goats: pharmacology, efficacy and use conditions in the context of anthelmintic resistance

Relative Neurotoxicity of Ivermectin and Moxidectin in Mdr1ab (-/-) Mice and Effects on Mammalian GABA(A) Channel Activity

Influence of Pluronic 85 and ketoconazole on disposition and efficacy of ivermectin in sheep infected with a multiple resistant Haemonchus contortus isolate

P-glycoprotein Dysfunction Contributes to Hepatic Steatosis and Obesity in Mice

P-glycoprotein Dysfunction Contributes to HepaticSteatosis and Obesity in Mice

Ivermectin Interacts With Human ABCG2

Interaction of anthelmintic drugs with P-glycoprotein in recombinant LLC-PK1-mdr1a cells

Role of P-Glycoprotein in the Disposition of Macrocyclic Lactones: A Comparison between Ivermectin, Eprinomectin, and Moxidectin in Mice

Influence of obesity on the pharmacokinetics of anthelmintic macrocyclic lactones in dogs

P-glycoprotein interfering agents potentiate ivermectin susceptibility in ivermectin sensitive and resistant isolates of Teladorsagia circumcincta and Haemonchus contortus

Interaction of macrocyclic lactones with the multidrug transporters: The bases of the pharmacokinetics of lipid-like drugs

Pharmacologie et efficacité des endectocides chez les caprins

Ketoconazole increases the plasma levels of ivermectin in sheep

Les endectocides chez les caprins : pharmacologie, efficacité et conditions d'utilisation dans le contexte de la résistance aux anthelminthiques

ABC transporter modulation: a strategy to enhance the activity of macrocyclic lactone anthelmintics

Multiple oral dosing of ketoconazole increases dog exposure to ivermectin

Interaction of macrocyclic lactones with P-glycoprotein : Structure - affinity relationship Eur

Estimation of absolute oral bioavailability of moxidectin in dogs using a semi-simultaneous method: influence of lipid co-administration.

Interaction of macrocyclic lactones with P-glycoprotein: Structure-affinity relationship

Fumagillin, a new P-glycoprotein-interfering agent able to modulate moxidectin efflux in rat hepatocytes

Assessment of a liposomal formulation of ivermectin in rabbit after a single subcutaneous administration

The interaction between moxidectin and MDR transporters in primary cultures of rat hepatocytes

Contribution of lymphatic transport to the systemic exposure of orally administered moxidectin in conscious lymph duct-cannulated dogs.

Interaction of ivermectin with multidrug resistance proteins (MRP1, 2 and 3)

Influence of dyslipidemia on moxidectin distribution in plasma lipoproteins and on its pharmacokinetics

Influence of the route of administration on efficacy and tissue distribution of ivermectin in goat

Efficacy of eprinomectin pour-on against gastrointestinal nematodes and the nasal bot fly (Oestrus ovis) in sheep

The influence of parasitism on the pharmacokinetics of moxidectin in lambs

The influence of parasitism on the pharmacokinetics of moxidectin in lambs

Macrocyclic lactones: distribution in plasma lipoproteins of several animal species including humans

Enhancement of oral moxidectin bioavailability in rabbits by lipid co-administration

Efficacy of injectable and pour-on microdose ivermectin in the treatment of goat warble fly infestation by Przhevalskiana silenus (Diptera, Oestridae)

Enhancement of moxidectin bioavailability in lamb by a natural flavonoid: quercetin

The comparative serum disposition kinetics of subcutaneous administration of doramectin, ivermectin and moxidectin in the Australian Merino sheep

Pharmacokinetics of ivermectin in the yak (Bos grunniens)

Eprinomectin in goat: assessment of subcutaneous administration

P-Glycoproteins 6 and 9 role in ivermectin resistance in the nematode model Caenorhabditis elegans

Effect of sainfoin (Onobrychis viciifolia) on cyathostomin eggs excretion, larval development, larval community structure and efficacy of ivermectin treatment in horses

Selected resistance to macrocyclic lactone exhibit modulation of amphid structure and function at genetic level

Le récepteur nucléaire NRH-8 : une nouvelle cible pour augmenter l’efficacité de l’ivermectine chez les nématodes

Resistance to macrocyclic lactones: Is there a fitness cost of acquired tolerance to ivermectin and moxidectin in Caenorhabditis elegans?

In vitro comparison of the effect of flavonoids in anthelmintic resistant and susceptible isolates of Haemonchus contortus: preliminary results

Deux mutations rares chez l'homme responsables de la toxicité du traitement contre la gâle