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Combination of lentiviral and genome editing technologies for the treatment of sickle cell disease

Sophie Ramadier , Anne Chalumeau , Tristan Felix , Nadia Othman , Sherazade Aknoun , et al.
Molecular Therapy, 2022, 30 (1), pp.145-163. ⟨10.1016/j.ymthe.2021.08.019⟩
Article dans une revue hal-03531070v1

Iron complexes of terdentate nitrogen ligands: formation and X-ray structure of three new dicationic complexes

F. Pelascini , Manuel Wesolek , F. Peruch , A de Cian , N. Kyritsakas , et al.
Polyhedron, 2004, 23 (18), pp.3193-3199. ⟨10.1016/j.poly.2004.10.001⟩
Article dans une revue istex hal-03144983v1

Plasmodium telomeric sequences: structure, stability and quadruplex targeting by small compounds

A. de Cian , P. Grellier , E. Mouray , D. Depoix , Hélène Bertrand , et al.
ChemBioChem, 2008, 9, pp.2730
Article dans une revue hal-00339356v1

Stimulation of the human RAD51 nucleofilament restricts HIV-1 integration in vitro and in infected cells.

O. Cosnefroy , A. Tocco , P. Lesbats , S. Thierry , C. Calmels , et al.
Journal of Virology, 2012, 86 (1), pp.513-26. ⟨10.1128/JVI.05425-11⟩
Article dans une revue hal-00675716v1
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Cooperation, cis-interactions, versatility and evolutionary plasticity of multiple cis-acting elements underlie krox20 hindbrain regulation

Patrick Torbey , Elodie Thierion , Samuel Collombet , Anne de Cian , Carole Desmarquet-Trin-Dinh , et al.
PLoS Genetics, 2018, 14 (8), pp.e1007581. ⟨10.1371/journal.pgen.1007581⟩
Article dans une revue hal-01876045v1

Stimulation of the Human RAD51 Nucleofilament Restricts HIV-1 Integration In Vitro and in Infected Cells

O. Cosnefroy , A. Tocco , P. Lesbats , S. Thierry , C. Calmels , et al.
Journal of Virology, 2011, 86 (1), pp.513-526. ⟨10.1128/jvi.05425-11⟩
Article dans une revue hal-03065212v1

Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action.

Anne de Cian , G. Cristofari , P. Reichenbach , E. de Lemos , David Monchaud , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2007, 104 (44), pp.17347-52. ⟨10.1073/pnas.0707365104⟩
Article dans une revue hal-00259071v1

Fine tuning of the [2+2] vs [4+2] selectivity of 1,1-disubstituted dienes in cycloaddition reactions

T. Zoller , P. Breuilles , S. Klein , D. Uguen , A. de Cian , et al.
Tetrahedron Letters, 1999, 40 (51), pp.9015-9018. ⟨10.1016/S0040-4039(99)01884-5⟩
Article dans une revue istex hal-02308648v1
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Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins

Séverine Ménoret , Anne de Cian , Laurent Tesson , Séverine Remy , Claire Usal , et al.
Scientific Reports, 2015, 5, pp.14410. ⟨10.1038/srep14410⟩
Article dans une revue hal-01271745v1
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High doses of CRISPR/Cas9 ribonucleoprotein efficiently induce gene knockout with low mosaicism in the hydrozoan Clytia hemisphaerica through microhomology-mediated deletion

Tsuyoshi R Momose , Anne de Cian , Kogiku Shiba , Kazuo Inaba , Carine Giovannangeli , et al.
Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-018-30188-0⟩
Article dans une revue hal-02142636v1

The importance of metal geometry in the recognition of G-quadruplex-DNA by metal-terpyridine complexes

Hélène Bertrand , David Monchaud , Anne de Cian , Régis Guillot , Jean-Louis Mergny , et al.
Organic & Biomolecular Chemistry, 2007, 5 (16), pp.2555. ⟨10.1039/B708635K⟩
Article dans une revue istex hal-02124571v1

ATP-Independent Cooperative Binding of Yeast Isw1a to Bare and Nucleosomal DNA

Anne de Cian , Elise Praly , Fangyuan Ding , Vijender Singh , Christophe Lavelle , et al.
PLoS ONE, 2012, 7 (2), pp.e31845. ⟨10.1371/journal.pone.0031845⟩
Article dans une revue hal-03065210v1
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Characterization of Dystrophin Deficient Rats: A New Model for Duchenne Muscular Dystrophy

Thibaut Larcher , Aude Lafoux , Laurent Tesson , Severine Remy , Virginie Thepenier , et al.
PLoS ONE, 2014, 9 (10), 13 p. ⟨10.1371/journal.pone.0110371⟩
Article dans une revue hal-01190124v1
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Improved Genome Editing Efficiency and Flexibility Using Modified Oligonucleotides with TALEN and CRISPR-Cas9 Nucleases.

Jean-Baptiste Renaud , Charlotte Boix , Marine Charpentier , Anne de Cian , Julien Cochennec , et al.
Cell Reports, 2016, 14 (9), pp.2263-72. ⟨10.1016/j.celrep.2016.02.018⟩
Article dans une revue hal-01371505v1

Synthesis and Properties of Oligo[n]cruciforms : Nanosized Sterically Encumbered Tetraethynylphenyl-Homologated Fluorophores

A. Al Ouahabi , P. N. W. Baxter , J. P. Gisselbrecht , A. de Cian , L. Brelot , et al.
Journal of Organic Chemistry, 2009, 74 (13), pp.4675-4689
Article dans une revue hal-00430672v1
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Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human Cells

Edwige B Garcin , Stéphanie Gon , Meghan Sullivan , Gregory J Brunette , Anne De Cian , et al.
PLoS Genetics, 2019, 15 (10), pp.e1008355. ⟨10.1371/journal.pgen.1008355⟩
Article dans une revue hal-02383639v1

A new steroid derivative stabilizes g-quadruplexes and induces telomere uncapping in human tumor cells.

Alain Montagnac , Khuong-Huu Qui , Françoise Gueritte , B. Brassart , D. Gomez , et al.
Molecular Pharmacology, 2007, 72 (3), pp.631-40. ⟨10.1124/mol.107.036574⟩
Article dans une revue hal-00184644v1

Ligands playing musical chairs with G-quadruplex DNA: A rapid and simple displacement assay for identifying selective G-quadruplex binders

D. Monchaud , C. Allain , H. Bertrand , N. Smargiasso , F. Rosu , et al.
Biochimie, 2008, 90 (8), pp.1207-1223. ⟨10.1016/j.biochi.2008.02.019⟩
Article dans une revue hal-02125647v1

Highly Efficient G-Quadruplex Recognition by Bisquinolinium Compounds

Anne de Cian , Elsa Delemos , Jean-Louis Mergny , Marie-Paule Teulade-Fichou , David Monchaud
Journal of the American Chemical Society, 2007, 129 (7), pp.1856-1857. ⟨10.1021/ja067352b⟩
Article dans une revue istex hal-02124562v1

Highly efficient G-quadruplex recognition by bisquinolinium compounds.

Anne de Cian , Elsa Delemos , Jean-Louis Margny , Marie-Paule Teulade-Fichou , David Monchaud
Journal of the American Chemical Society, 2007, 129 (7), pp.1856-7. ⟨10.1021/ja067352b⟩
Article dans une revue istex hal-00258125v1

An unexpected sequel of an alcohol oxidation study: Stereoselective cyclisation of an unsaturated keto-sulfide

T. Zoller , P. Breuilles , D. Uguen , A. de Cian , J. Fischer
Tetrahedron Letters, 1999, 40 (34), pp.6253-6256. ⟨10.1016/S0040-4039(99)01298-8⟩
Article dans une revue istex hal-02308636v1

Ligands playing musical chairs with G-quadruplex DNA: a rapid and simple displacement assay for identifying selective G-quadruplex binders

David Monchaud , Clémence Allain , Hélène Bertrand , Nicolas Smargiasso , Frédéric Rosu , et al.
Biochimie, 2008, 90 (8), pp.1207-1223. ⟨10.1016/j.biochi.2008.02.019⟩
Article dans une revue hal-00311781v1

Fluorescence-based melting assays for studying quadruplex ligands.

Anne de Cian , Lionel Guittat , Markus Kaiser , Barbara Saccà , Samir Amrane , et al.
Methods, 2007, 42 (2), pp.183-95. ⟨10.1016/j.ymeth.2006.10.004⟩
Article dans une revue istex hal-00258193v1
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Unraveling Ewing Sarcoma Tumorigenesis Originating from Patient-Derived Mesenchymal Stem Cells

Anna Sole , Sandrine Grossetête , Maxime Heintzé , Loelia Babin , Sakina Zaïdi , et al.
Cancer Research, 2021, 81 (19), pp.4994-5006. ⟨10.1158/0008-5472.CAN-20-3837⟩
Article dans une revue mnhn-03873854v1

Urp1 and Urp2 act redundantly to maintain spine shape in zebrafish larvae

Anne-Laure Gaillard , Teddy Mohamad , Feng Quan , Anne de Cian , Christian Mosimann , et al.
2023
Pré-publication, Document de travail hal-03935642v1
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Editing a γ-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype

Leslie Weber , Giacomo Frati , Tristan Felix , Giulia Hardouin , Antonio Casini , et al.
Science Advances , 2020, 6 (7), pp.eaay9392. ⟨10.1126/sciadv.aay9392⟩
Article dans une revue mnhn-03100446v1
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Identification et caractérisation de ligands des quadruplexes de guanines: cibler les télomères et/ou la télomérase?

Anne de Cian
Biochimie [q-bio.BM]. Université Pierre et Marie Curie - Paris VI, 2007. Français. ⟨NNT : ⟩
Thèse tel-00440832v1

The importance of metal geometry in the recognition of G-quadruplex-DNA by metal-terpyridine complexes.

Hélène Bertrand , David Monchaud , Anne de Cian , Régis Guillot , Jean-Louis Mergny , et al.
Organic & Biomolecular Chemistry, 2007, 5 (16), pp.2555-9
Article dans une revue hal-00259076v1

Plasmodium Telomeric Sequences: Structure, Stability and Quadruplex Targeting by Small Compounds

Anne de Cian , Philippe Grellier , Elisabeth Mouray , Delphine Depoix , Hélène Bertrand , et al.
ChemBioChem, 2008, 9 (16), pp.2730-2739. ⟨10.1002/cbic.200800330⟩
Article dans une revue hal-02125633v1
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Gene targeting in rats using transcription activator-like effector nucleases

Séverine Ménoret , Laurent Tesson , Severine Rémy , Claire Usal , Virginie Thépenier , et al.
Methods, 2014, 69 (1), pp.102-107. ⟨10.1016/j.ymeth.2014.02.027⟩
Article dans une revue inserm-02164327v1