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Evaluation of the inhibitory activity of (aza)isoindolinone-type compounds: toward in vitro InhA action, Mycobacterium tuberculosis growth and mycolic acid biosynthesis
Aurélien Chollet
,
Jean-Luc Stigliani
,
Maria Rosalia Pasca
,
Giorgia Mori
,
Christian Lherbet
,
et al.
Article dans une revue
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hal-01929908v1
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1H and 13C NMR characterization of isoniazid-NAD pyridinium-type adducts as possible inhibitors of InhA reductase of Mycobacterium tuberculosis
Sylvain Broussy
,
Vania Bernardes-Génisson
,
Yannick Coppel
,
A. Quémard
,
Jean Bernadou
,
et al.
Organic & Biomolecular Chemistry, 2005, 3, pp.670-673
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hal-00078731v1
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The first chemical synthesis of the core structure of the benzoylhydrazine-NAD adduct, a competitive inhibitor of the Mycobacterium tuberculosis enoyl reductase
Sylvain Broussy
,
Vania Bernardes-Génisson
,
A. Quémard
,
Jean Bernadou
,
B. Meunier
Journal of Organic Chemistry, 2005, 70, pp.10502-10510
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hal-00077300v1
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HadD, a novel fatty acid synthase type II protein, is essential for alpha- and epoxy-mycolic acid biosynthesis and mycobacterial fitness
Cyril Lefebvre
,
Richard Boulon
,
Manuelle Ducoux
,
Sabine Gavalda
,
Françoise Laval
,
et al.
Article dans une revue
hal-02179486v1
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The Polyketide Synthase Pks13 Catalyzes a Novel Mechanism of Lipid Transfer in Mycobacteria
Sabine Gavalda
,
Fabienne Bardou
,
Françoise Laval
,
Cécile Bon
,
Wladimir Malaga
,
et al.
Article dans une revue
hal-03002982v1
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Negative regulation by Ser/Thr phosphorylation of HadAB and HadBC dehydratases from Mycobacterium tuberculosis type II fatty acid synthase system
Nawel Slama
,
Jade Leiba
,
Nathalie Eynard
,
Mamadou Daffé
,
Laurent Kremer
,
et al.
Article dans une revue
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hal-02282724v1
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The Dual Function of the Mycobacterium tuberculosis FadD32 Required for Mycolic Acid Biosynthesis
Mathieu Léger
,
Sabine Gavalda
,
Valérie Guillet
,
Benoît van Der Rest
,
Nawel Slama
,
et al.
Article dans une revue
hal-03003389v1
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Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases
Alexandre Faille
,
Sabine Gavalda
,
Nawel Slama
,
Christian Lherbet
,
Laurent Maveyraud
,
et al.
Article dans une revue
hal-03002100v1
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Rv3389C from Mycobacterium tuberculosis, a member of the (R)-specific hydratase/dehydratase family
Emmanuelle Sacco
,
Virginie Legendre
,
Françoise Laval
,
Didier Zerbib
,
Henri Montrozier
,
et al.
Article dans une revue
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hal-01883516v1
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Enzymic Characterization of the Target for Isoniazid in Mycobacterium tuberculosis
Annaïk Quémard
,
Annaiek Quemard
,
James Sacchettini
,
Andréa Dessen
,
Catherine Vilcheze
,
et al.
Article dans une revue
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hal-03066406v1
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Biochemical and Structural Study of the Atypical Acyltransferase Domain from the Mycobacterial Polyketide Synthase Pks13
Fabien Bergeret
,
Sabine Gavalda
,
Christian Chalut
,
Wladimir Malaga
,
Annaïk Quémard
,
et al.
Article dans une revue
hal-03003064v1
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Ligand-induced fit in mycobacterial MabA: the sequence-specific C-terminus locks the conformational change
M. Cohen-Gonsaud
,
S. Ducasse
,
A. Quémard
,
G. Labesse
Proteins - Structure, Function and Bioinformatics, 2005, 60 (3), pp.392-400
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hal-00077525v1
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Design, synthesis and evaluation of new GEQ derivatives as inhibitors of InhA enzyme and Mycobacterium tuberculosis growth
Aurélien Chollet
,
Georgia Mori
,
Christophe Menendez
,
Frédéric Rodriguez
,
Isabelle Fabing
,
et al.
Article dans une revue
hal-01920338v1
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The Pks13/FadD32 Crosstalk for the Biosynthesis of Mycolic Acids in Mycobacterium tuberculosis
Sabine Gavalda
,
Mathieu Léger
,
Benoît van Der Rest
,
Alexandre Stella
,
Fabienne Bardou
,
et al.
Article dans une revue
hal-03003050v1
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Further Insight into S-Adenosylmethionine-dependent Methyltransferases: STRUCTURAL CHARACTERIZATION OF Hma, AN ENZYME ESSENTIAL FOR THE BIOSYNTHESIS OF OXYGENATED MYCOLIC ACIDS IN MYCOBACTERIUM TUBERCULOSIS
Fanny Boissier
,
Fabienne Bardou
,
Valérie Guillet
,
Sandrine Uttenweiler-Joseph
,
Mamadou Daffé
,
et al.
Article dans une revue
hal-03003456v1
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HadBD dehydratase from Mycobacterium tuberculosis fatty acid synthase type II : A singular structure for a unique function
Pascaline Bories
,
Julie Rima
,
Samuel Tranier
,
Julien Marcoux
,
Yasmina Grimoire
,
et al.
Article dans une revue
hal-04514640v1
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Preliminary Investigations of the Effect of Lipophilic Analogues of the Active Metabolite of Isoniazid Toward Bacterial and Plasmodial Strains
Tamara Delaine
,
Vania Bernardes-Génisson
,
Annaïk Quémard
,
Patricia Constant
,
Frédéric Coslédan
,
et al.
Article dans une revue
hal-02909742v1
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Mycobacterium bovis BCG genes involved in the biosynthesis of cyclopropyl keto‐ and hydroxy‐mycolic acids
Eugenie Dubnau
,
Marie‐antoinette Lanéelle
,
Sonia Soares
,
Anne Bénichou
,
Tania Vaz
,
et al.
Article dans une revue
hal-03066402v1
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Crystal Structure of MabA from Mycobacterium tuberculosis, a Reductase involved in Long-chain Fatty Acid Biosynthesis
Martin Cohen-Gonsaud
,
Stéphanie Ducasse
,
Francois Hoh
,
Didier Zerbib
,
Gilles Labesse
,
et al.
Article dans une revue
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hal-02359522v1
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Mycolic Acids: From Chemistry to Biology
Mamadou Daffé
,
Annaïk Quémard
,
Hedia Marrakchi
Chapitre d'ouvrage
hal-02388910v1
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Acylation of glycerolipids in mycobacteria
Shiva Kumar Angala
,
Ana Carreras-Gonzalez
,
Emilie Huc-Claustre
,
Itxaso Anso
,
Devinder Kaur
,
et al.
Article dans une revue
hal-04264659v1
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The changes in mycolic acid structures caused by hadC mutation have a dramatic effect on the virulence of Mycobacterium tuberculosis
Nawel Slama
,
Stevie Jamet
,
Wafa Frigui
,
Alexandre Pawlik
,
Daria Bottai
,
et al.
Article dans une revue
pasteur-02618562v1
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Discovery of a novel dehydratase of the fatty acid synthase type II critical for ketomycolic acid biosynthesis and virulence of Mycobacterium tuberculosis
Cyril Lefebvre
,
Wafa Frigui
,
Nawel Slama
,
Françoise Lauzeral-Vizcaino
,
Patricia Constant
,
et al.
Article dans une revue
pasteur-02474005v1
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S-Adenosyl-N-decyl-aminoethyl, a Potent Bisubstrate Inhibitor ofMycobacterium tuberculosisMycolic Acid Methyltransferases
Julien Vaubourgeix
,
Fabienne Bardou
,
Fanny Boissier
,
Sylviane Julien
,
Patricia Constant
,
et al.
Article dans une revue
hal-03003382v1
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