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alpha-L-Arabinofuranosylated pyrrolidines as arabinanase inhibitors

Ethan Goddard-Borger , Raphaël Carapito , Jean-Marc Jeltsch , Vincent Phalip , Robert Stick , et al.
Chemical Communications, 2011, 47 (34), pp.9684-9686. ⟨10.1039/c1cc13675e⟩
Article dans une revue hal-03408190v1
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Structure and engineering of tandem repeat lectins

Simona Notova , François Bonnardel , Frédérique Lisacek , Annabelle Varrot , Anne Imberty
Current Opinion in Structural Biology, 2020, 62, pp.39-47. ⟨10.1016/j.sbi.2019.11.006⟩
Article dans une revue hal-02463790v1
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Targeting a Multidrug-Resistant Pathogen: First Generation Antagonists of Burkholderia cenocepacia ’s BC2L-C Lectin

Rafael Bermeo , Kanhaya Lal , Davide Ruggeri , Daniele Lanaro , Sarah Mazzotta , et al.
ACS Chemical Biology, 2022, ⟨10.1021/acschembio.2c00532⟩
Article dans une revue hal-03795919v1

Multivalent Fucosides with Nanomolar Affinity for the Aspergillus fumigatus Lectin FleA Prevent Spore Adhesion to Pneumocytes

Victor Lehot , Yoan Brissonnet , Christophe Dussouy , Sami Brument , Aurore Cabanettes , et al.
Chemistry - A European Journal, 2018, 24 (72), pp.19243-19249. ⟨10.1002/chem.201803602⟩
Article dans une revue hal-02140873v1
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Discovery of N -β- l -Fucosyl Amides as High-Affinity Ligands for the Pseudomonas aeruginosa Lectin LecB

Patrycja Mała , Eike Siebs , Joscha Meiers , Katharina Rox , Annabelle Varrot , et al.
Journal of Medicinal Chemistry, 2022, 65 (20), pp.14180-14200. ⟨10.1021/acs.jmedchem.2c01373⟩
Article dans une revue hal-03834673v1
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The choanoflagellate pore-forming lectin SaroL-1 punches holes in cancer cells by targeting the tumor-related glycosphingolipid Gb3

Simona Notova , François Bonnardel  , Francesca Rosato , Lina Siukstaite , Jessica Schwaiger , et al.
Communications Biology, 2022, 5 (1), pp.954. ⟨10.1038/s42003-022-03869-w⟩
Article dans une revue hal-03775900v1
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Deciphering the Glycan Preference of Bacterial Lectins by Glycan Array and Molecular Docking with Validation by Microcalorimetry and Crystallography

Jeremie Topin , Julie Arnaud , Anita Sarkar , Aymeric Audfray , Emilie Gillon , et al.
PLoS ONE, 2013, pp.e71149. ⟨10.1371/journal.pone.0071149⟩
Article dans une revue hal-03068180v1
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Hexavalent thiofucosides to probe the role of the Aspergillus fumigatus lectin FleA in fungal pathogenicity

Christophe Dussouy , Pierre-Alban Lalys , Aurore Cabanettes , Victor Lehot , David Deniaud , et al.
Organic & Biomolecular Chemistry, 2021, 19 (14), pp.3234-3240. ⟨10.1039/D1OB00152C⟩
Article dans une revue hal-03429198v1
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Structural insights into Aspergillus fumigatus lectin specificity: AFL binding sites are functionally non-equivalent

Josef Houser , Jan Komarek , Gianluca Cioci , Annabelle Varrot , Anne Imberty , et al.
Acta crystallographica Section D : Structural biology [1993-..], 2015, 71 (3), pp.442-453. ⟨10.1107/S1399004714026595⟩
Article dans une revue hal-03641311v1
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A Recombinant Fungal Lectin for Labeling Truncated Glycans on Human Cancer Cells

Aymeric Audfray , Mona Beldjoudi , Adrien Breiman , Amandine Hurbin , Irene Boos , et al.
PLoS ONE, 2015, 10 (6), pp.e0128190. ⟨10.1371/journal.pone.0128190⟩
Article dans une revue hal-02349425v1
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Non‐Carbohydrate Glycomimetics as Inhibitors of Calcium(II)‐binding Lectins

Sakonwan Kuhaudomlarp , Eike Siebs , Elena Shanina , Jérémie Topin , Ines Joachim , et al.
Angewandte Chemie International Edition, 2021, 60 (15), pp.8104-8114. ⟨10.1002/anie.202013217⟩
Article dans une revue hal-03083693v2

O -Alkylated heavy atom carbohydrate probes for protein X-ray crystallography: Studies towards the synthesis of methyl 2- O -methyl-L-selenofucopyranoside

Roman Sommer , Dirk Hauck , Annabelle Varrot , Anne Imberty , Markus Künzler , et al.
Beilstein Journal of Organic Chemistry, 2016, 12, pp.2828-2833. ⟨10.3762/bjoc.12.282⟩
Article dans une revue hal-02381861v1
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Recognition of Complex Core-Fucosylated N-Glycans by a Mini Lectin

Aurore Cabanettes , Lukas Perkams , Carolina Spies , Carlo Unverzagt , Annabelle Varrot
Angewandte Chemie International Edition, 2018, 57 (32), pp.10178 - 10181. ⟨10.1002/anie.201805165⟩
Article dans une revue hal-01880792v1
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LecA (PA-IL), a Galactose-Binding Lectin from Pseudomonas aeruginosa

Sakonwan Kuhaudomlarp , Émilie Gillon , Annabelle Varrot , Anne Imberty
Methods in Molecular Biology, 2020, Lectin purification and analysis, 2132, pp.257-266. ⟨10.1007/978-1-0716-0430-4_25⟩
Article dans une revue hal-02554317v1

Crystal structure of a mannose-specific lectin from Burkholderia cenocepacia. Occurrence in bacteria of B. cepacia complex and comparison with PA-IIL from Pseudomonas aeruginosa

E Lameignere , L Malinovska , M Pokorna , Éric Duchaud , Ep Mitchell , et al.
Biochemical Journal, 2008, 411, pp.307-318
Article dans une revue hal-02653241v1

Structure determination of Discoidin II from Dictyostelium discoideum and carbohydrate binding properties of the lectin domain.

Karoline Saboia Aragão , Michel Satre , Anne Imberty , Annabelle Varrot
Proteins - Structure, Function and Bioinformatics, 2008, 73 (1), pp.43-52. ⟨10.1002/prot.22038⟩
Article dans une revue istex hal-00320152v1
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Biophysical characterization and structural determination of the potent cytotoxic Psathyrella asperospora lectin

João P. Ribeiro , Mohamed Ali Abol Hassan , Razina Rouf , Evelin Tiralongo , Tom W. May , et al.
Proteins - Structure, Function and Bioinformatics, 2017, 85 (5), pp.969-975. ⟨10.1002/prot.25265⟩
Article dans une revue hal-02378060v1
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Effect of Noncanonical Amino Acids on Protein–Carbohydrate Interactions: Structure, Dynamics, and Carbohydrate Affinity of a Lectin Engineered with Fluorinated Tryptophan Analogs

Felix Tobola , Mickaël Lelimousin , Annabelle Varrot , Emilie Gillon , Barbara Darnhofer , et al.
ACS Chemical Biology, 2018, 13 (8), pp.2211-2219. ⟨10.1021/acschembio.8b00377⟩
Article dans une revue hal-02106155v1
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Covalent lectin inhibition and its application in bacterial biofilm imaging

Stefanie Wagner , Dirk Hauck , Michael Hoffmann , Roman Sommer , Ines Joachim , et al.
Angewandte Chemie International Edition, 2017, 56 (52), pp.16559-16564. ⟨10.1002/anie.201709368⟩
Article dans une revue hal-02310009v1
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Glycomimetic, Orally Bioavailable LecB Inhibitors Block Biofilm Formation of Pseudomonas aeruginosa

Roman Sommer , Stefanie Wagner , Katharina Rox , Annabelle Varrot , Dirk Hauck , et al.
Journal of the American Chemical Society, 2018, 140 (7), pp.2537-2545. ⟨10.1021/jacs.7b11133⟩
Article dans une revue hal-02106161v1

Crystal Structures of Fungal Tectonin in Complex with O-Methylated Glycans Suggest Key Role in Innate Immune Defense

Roman Sommer , Olga N Makshakova , Therese Wohlschlager , Stephanie Hutin , May Marsh , et al.
Structure, 2018, 26 (3), pp.391 - 402. ⟨10.1016/j.str.2018.01.003⟩
Article dans une revue hal-01902618v1
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Anti-biofilm Agents against Pseudomonas aeruginosa : A Structure–Activity Relationship Study of C -Glycosidic LecB Inhibitors

Roman Sommer , Katharina Rox , Stefanie Wagner , Dirk Hauck , Sarah Henrikus , et al.
Journal of Medicinal Chemistry, 2019, 62 (20), pp.9201-9216. ⟨10.1021/acs.jmedchem.9b01120⟩
Article dans une revue hal-02349120v1
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Structural basis for mannose recognition by alectin from opportunistic bacteria Burkholderia cenocepacia

Emilie Lameignere , Lenka Malinovska , Margita Slavikova , Éric Duchaud , Edward P Mitchell , et al.
Biochemical Journal, 2008, 411 (2), pp.307-318. ⟨10.1042/bj20071276⟩
Article dans une revue hal-00479454v1
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Prediction and Validation of a Druggable Site on Virulence Factor of Drug Resistant Burkholderia cenocepacia

Kanhaya Lal , Rafael Bermeo , Jonathan Cramer , Francesca Vasile , Beat Ernst , et al.
ACS Chemical Biology, 2022, ⟨10.1002/chem.202100252⟩
Article dans une revue hal-03198933v1
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Molecular Basis of Arabinobio-hydrolase Activity in Phytopathogenic Fungi CRYSTAL STRUCTURE AND CATALYTIC MECHANISM OF FUSARIUM GRAMINEARUM GH93 EXO-alpha-L-ARABINANASE

Raphaël Carapito , Anne Imberty , Jean Jeltsch , Simon Byrns , Pui Tam , et al.
Journal of Biological Chemistry, 2009, 284 (18), pp.12285-12296. ⟨10.1074/jbc.M900439200⟩
Article dans une revue hal-03408197v1
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Expression, Purification, and Applications of the Recombinant Lectin PVL from Psathyrella velutina Specific for Terminal N-Acetyl-Glucosamine

Oriane Machon , Annabelle Varrot
Lectin Purification and Analysis. Methods in Molecular Biology, pp.421-436, 2020, ⟨10.1007/978-1-0716-0430-4_41⟩
Chapitre d'ouvrage hal-02928046v1

High Affinity Interaction between a Bivalve C-type Lectin and a Biantennary Complex-type N -Glycan Revealed by Crystallography and Microcalorimetry

Juliette Smith-Ravin , Jean-Philippe Gourdine , Gianluca Cioci , Laurence Miguet , Carlo Unverzagt , et al.
Journal of Biological Chemistry, 2008, 283 (44), pp.30112 - 30120. ⟨10.1074/jbc.M804353200⟩
Article dans une revue hal-01700354v1
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Induction of rare conformation of oligosaccharide by binding to calcium-dependent bacterial lectin: X-ray crystallography and modelling study

Martin Lepsik , Roman Sommer , Sakonwan Kuhaudomlarp , Mickaël Lelimousin , Emanuele Paci , et al.
European Journal of Medicinal Chemistry, 2019, 177, pp.212-220. ⟨10.1016/j.ejmech.2019.05.049⟩
Article dans une revue hal-02309977v1

Carbohydrate binding specificities and crystal structure of the cholera toxin-like B-subunit from Citrobacter freundii

Lena Jansson , Jonas Angstrom , Michael Lebens , Anne Imberty , Annabelle Varrot , et al.
Biochimie, 2010, 92 (5), pp.482-490. ⟨10.1016/j.biochi.2010.02.010⟩
Article dans une revue istex hal-00499332v1
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Biochemical and structural characterization of the novel sialic acid-binding site of Escherichia coli heat-labile enterotoxin LT-IIb

Dani Zalem , Joao Ribeiro , Annabelle Varrot , Michael Lebens , Anne Imberty , et al.
Biochemical Journal, 2016, 473 (21), pp.3923-3936. ⟨10.1042/BCJ20160575⟩
Article dans une revue hal-02381852v1