Angélique Stéphanou

Documents

Publications

	On the Importance of Acidity in Cancer Cells and Therapy Alaa Tafech , Angélique Stéphanou Biology, 2024, 13 (4), pp.225. ⟨10.3390/biology13040225⟩ Article dans une revue hal-04527526v1
	A reduced model of cell metabolism to revisit the glycolysis-OXPHOS relationship in the deregulated tumor microenvironment Pierre Jacquet , Angélique Stéphanou Journal of Theoretical Biology, 2023, 562, pp.111434. ⟨10.1016/j.jtbi.2023.111434⟩ Article dans une revue hal-03973607v1
	Generalization of the Ratiometric Method to Extend pH Range Measurements of the BCECF Probe Alaa Tafech , Céline Beaujean , Yves Usson , Angélique Stéphanou Biomolecules, 2023, 13 (3), pp.442. ⟨10.3390/biom13030442⟩ Article dans une revue hal-04287591v1
	Characterization of the Intracellular Acidity Regulation of Brain Tumor Cells and Consequences for Therapeutic Optimization of Temozolomide Alaa Tafech , Pierre Jacquet , Céline Beaujean , Arnold Fertin , Yves Usson Biology, 2023, 12 (9), pp.1221. ⟨10.3390/biology12091221⟩ Article dans une revue hal-04208184v1
	Searching for the Metabolic Signature of Cancer: A Review from Warburg’s Time to Now Pierre Jacquet , Angélique Stéphanou Biomolecules, 2022, 12 (10), pp.1412. ⟨10.3390/biom12101412⟩ Article dans une revue hal-03813369v1
	Modelling the role of HIF in the regulation of metabolic key genes LDH and PDH: Emergence of Warburg Phenotype Kévin Spinicci , Pierre Jacquet , Gibin Powathil , Angélique Stéphanou Computational and Systems Oncology, 2022, 2 (3), ⟨10.1002/cso2.1040⟩ Article dans une revue hal-03759747v1
	Can major breakthroughs in cancer be achieved through theoretical models? Comment on “Improving cancer treatments via dynamical biophysical models” by M. Kuznetsov, J. Clairambault and V. Volpert Angélique Stéphanou Physics of Life Reviews, 2022, 40, pp.63-64. ⟨10.1016/j.plrev.2021.11.006⟩ Article dans une revue hal-03470089v1
	Metabolic Reprogramming, Questioning, and Implications for Cancer Pierre Jacquet , Angélique Stéphanou Biology, 2021, 10 (2), pp.129. ⟨10.3390/biology10020129⟩ Article dans une revue hal-03151101v1
	On the importance of substrate deformations for cell migration Anais Gagnieu , Grégory Chagnon , Yves Chemisky , Angélique Stephanou , Arnaud Chauvière Computer Methods in Biomechanics and Biomedical Engineering, 2020, 22 suppl 1, pp.S334-S335. ⟨10.1080/10255842.2020.1714933⟩ Article dans une revue hal-02425956v1
	A minimal biomechanical model for random cell migration Ian Manifacier , Arnaud Chauvière , Claude Verdier , G. Chagnon , Ibrahim Cheddadi Computer Methods in Biomechanics and Biomedical Engineering, 2020, 45th Congress of the Société de Biomécanique, 23 (sup1), pp.S183-S185. ⟨10.1080/10255842.2020.1813420⟩ Article dans une revue hal-03015234v1
	HYBRID DATA-BASED MODELLING IN ONCOLOGY: SUCCESSES, CHALLENGES AND HOPES Angélique Stéphanou , Pascal Ballet , Gibin Powathil Mathematical Modelling of Natural Phenomena, 2020, 15, ⟨10.1051/mmnp/2019026⟩ Article dans une revue hal-02405782v1
	Hybrid Modelling in Oncology: Sucesses, Challenges and Hopes Angélique Stéphanou , Pascal Ballet , Gibin Powathil Mathematical Modelling of Natural Phenomena, 2020, 15, ⟨10.1051/mmnp/2019026⟩ Article dans une revue hal-01980757v1
	A minimal biomechanical model for random cell migration Ian Manifacier , Arnaud Chauvière , Claude Verdier , Gregory Chagnon , Ibrahim Cheddadi Computer Methods in Biomechanics & Biomedical Engineering, 2020, ⟨10.1080/10255842.2020.1813420⟩ Article dans une revue hal-02985515v1
	pH as a potential therapeutic target to improve temozolomide antitumor efficacy : A mechanistic modeling study Angélique Stéphanou , Annabelle Ballesta Pharmacology Research & Perspectives, 2019, 7 (1), pp.e00454. ⟨10.1002/prp2.454⟩ Article dans une revue hal-03015254v1
	Systems Biology, Systems Medicine, Systems Pharmacology: The What and The Why Angélique Stéphanou , Eric Fanchon , Pasquale Innominato , Annabelle Ballesta Acta Biotheoretica, 2018, 66 (4), pp.345-365. ⟨10.1007/s10441-018-9330-2⟩ Article dans une revue hal-01975961v1
	How tumour-induced vascular changes alter angiogenesis: Insights from a computational model Angélique Stéphanou , Anne-Cécile Lesart , J. Deverchere , A. Juhem , A. Popov Journal of Theoretical Biology, 2017, 419, pp.211-226 Article dans une revue hal-01975971v1
	Towards the Design of a Patient-Specific Virtual Tumour Flavien Caraguel , Anne-Cécile Lesart , François Estève , Boudewijn Pj van Der Sanden , Angélique Stéphanou Computational and Mathematical Methods in Medicine, 2016, 2016, pp.1-12. ⟨10.1155/2016/7851789⟩ Article dans une revue hal-01975976v1
	Hybrid Modelling in Cell Biology Angélique Stéphanou , Vitaly Volpert Mathematical Modelling of Natural Phenomena, 2015, 10 (1), pp.1-3. ⟨10.1051/mmnp/201510100⟩ Article dans une revue hal-01975989v1
	Effects of the hypoxia-mimetic agents DFO and CoCl2 on HeLa-FUCCI cells Baptiste Bedessem , Marie-Paule Montmasson , Malika Hamel , Françoise Giroud , Angélique Stéphanou Journal of Cell Biology and Cell Metab, 2015, 2, pp.4-12. ⟨10.24966/cbcm-1943/100004⟩ Article dans une revue hal-01483598v1
	A mathematical model of HiF-1α-mediated response to hypoxia on the G1/S transition Baptiste Bedessem , Angélique Stéphanou Mathematical Biosciences, 2014, 248, pp.31-9. ⟨10.1016/j.mbs.2013.11.007⟩ Article dans une revue hal-00977635v1
	Proceedings of the XXXIInd Seminar of the French-Speaking Society for Theoretical Biology; Saint-Flour (Cantal), France, 10-13 June, 2012. Nicolas Glade , Angélique Stéphanou Acta Biotheoretica, 2013, 61 (3), pp.289-90. ⟨10.1007/s10441-013-9201-9⟩ Article dans une revue hal-00977696v1
	Mathematical modelling and numerical simulations of actin dynamics in the eukaryotic cell. Uduak Z George , Angélique Stéphanou , Anotida Madzvamuse Journal of Mathematical Biology, 2013, 66 (3), pp.547-93. ⟨10.1007/s00285-012-0521-1⟩ Article dans une revue hal-00847003v1
	A Computational Framework to Assess the Efficacy of Cytotoxic Molecules and Vascular Disrupting Agents against Solid Tumours Margarita Pons-Salort , Boudewijn van Der Sanden , Aurélie Juhem , Andrei Popov , Angélique Stéphanou Mathematical Modelling of Natural Phenomena, 2012, 7 (1), pp.49-77. ⟨10.1051/mmnp/20127104⟩ Article dans une revue hal-00847022v1
	On the importance of the submicrovascular network in a computational model of tumour growth. Anne-Cécile Lesart , Boudewijn van Der Sanden , Lauriane Hamard , François Estève , Angélique Stéphanou Microvascular Research, 2012, 84 (2), pp.188-204. ⟨10.1016/j.mvr.2012.06.001⟩ Article dans une revue inserm-00738177v1
	On the Influence of Discrete Adhesive Patterns for Cell Shape and Motility: A Computational Approach Céline Franco , Tzvetelina Tzvetkova-Chevolleau , Angélique Stéphanou Mathematical Modelling of Natural Phenomena, 2010, 5 (1), pp.56 - 83. ⟨10.1051/mmnp/20105101⟩ Article dans une revue hal-00847012v1
	Modelling the Impact of Pericyte Migration and Coverage of Vessels on the Efficacy of Vascular Disrupting Agents Steven Mcdougall , Mark A.J. Chaplain , Angélique Stéphanou , Alexander R.A. Anderson Mathematical Modelling of Natural Phenomena, 2010, 5 (1), pp.163-202. ⟨10.1051/mmnp/20105108⟩ Article dans une revue hal-00847029v1
	The motility of normal and cancer cells in response to the combined influence of substrate rigidity and anisotropic microstructure Tzvetelina Tzvetkova-Chevolleau , Angélique Stéphanou , David Fuard , Jacques Ohayon , Patrick Schiavone Biomaterials, 2008, 29 (10), pp.1541--1551. ⟨10.1016/j.biomaterials.2007.12.016⟩ Article dans une revue hal-00291559v1
	Spatiotemporal dynamics of actin-rich adhesion microdomains: influence of substrate flexibility. Olivier Collin , Philippe Tracqui , Angélique Stephanou , Yves Usson , Jocelyne Clément-Lacroix Journal of Cell Science, 2006, 119 (Pt 9), pp.1914-25. ⟨10.1242/jcs.02838⟩ Article dans une revue inserm-00173037v1
	Spatiotemporal dynamics of actin-rich adhesion microdomains: influence of substrate flexibility O. Collin , Angélique Stéphanou Journal of Cell Science, 2006, 119 (9), pp.1914-1925 Article dans une revue hal-01976004v1
	The rigidity in fibrin gels as a contributing factor to the dynamics of in vitro vascular cord formation Angélique Stephanou , Ghislaine Meskaoui , Vailhé Bruno , Philippe Tracqui Microvascular Research, 2006, 73 (3), pp.182-190. ⟨10.1016/j.mvr.2006.12.002⟩ Article dans une revue hal-00193847v1
	A mathematical model for the dynamics of large membrane deformations of isolated fibroblasts Angélique Stéphanou Bulletin of Mathematical Biology, 2004, 66 (5), pp.1119-1154 Article dans une revue hal-01976003v1

	Le vivant discret et continu - modes de représentation en biologie théorique Nicolas Glade , Angélique Stéphanou Editions Matériologiques, pp.427, 2013, 978-2-919694-24-2 Ouvrages hal-00977657v1
	Spatio-temporal dynamics of the cell - characterization from images and computer-simulations Angélique Stéphanou Lambert Academic Publishing, pp.165, 2010, 9783838337920 Ouvrages hal-00977665v1

	Modélisation de la motilité cellulaire perturbée par l'interaction cellule-substrat Anais Gagnieu , Arnaud Chauvière , Grégory Chagnon , Yves Chemisky , Angélique Stephanou 38ème Séminaire de la Société Francophone de Biologie Théorique, Jun 2018, Sainf Flour, France Communication dans un congrès hal-01890322v1
	Hybrid modelling of mechanical cues in cell migration Angélique Stéphanou , Simon Lefloch , Arnaud Chauvière ITM Conference 2015, Workshop on Multiscale and Hybrid Modelling in Cell and Cell Population Biology, Mar 2015, Paris, France. ⟨10.1051/itmconf/20150500012⟩ Communication dans un congrès hal-01550582v1
	Reduced Model For 2D Tumor Growth and Tumor Induced Angiogenesis Mazen Alamir , Mirko Fiacchini , Angélique Stephanou ECC 2015 - 14th European Control Conference, Jul 2015, Linz, Austria Communication dans un congrès hal-01235354v1
	Mathematical Modelling of Fibroblast shape Transition on Arrays of Adhesive Micropatterns with Varying Pitch Angélique Stéphanou , Tzvetelina Tzvetkova-Chevolleau , David Fuard , Philippe Tracqui , Patrick Schiavone ECMTB08; European Conference on Mathematical and Theoretical Biology, Jun 2008, Edinburgh, United Kingdom Communication dans un congrès hal-00340399v1
	The Motility of Normal and Cancer Cells in Response to the Combined Influence of Substrate Rigidity and Anisotropic Nanostructure Tzvetelina Tzvetkova-Chevolleau , Angélique Stephanou , David Fuard , Jacques Ohayon , Patrick Schiavone ICBME2008, 13th International Conference on Biomedical Engineering, 2008, Singapore, Singapore Communication dans un congrès hal-00374519v1
	Control of cell morphodynamic and displacement orientation by precise tuning between substrate nanopatterning and rigidity Tzvetelina Tzvetkova-Chevolleau , David Fuard , Patrick Schiavone , Sébastien Decossas , Angélique Stéphanou Nanobio Europe 2008, Jun 2008, Barcelona, Spain Communication dans un congrès hal-00340397v1

	A computational framework integrating cytoskeletal and adhesion dynamics for modelling cell motility Angélique Stéphanou Cell mechanics: from single scale-based models to multiscale modeling, Chapman & Hall/CRC Mathematical and Computational Biology, pp.482, 2010, 9781420094541 Chapitre d'ouvrage hal-00977684v1

	Une Approche Computationnelle pour l'Etude de Processus Morphogénétiques - de la motilité des cellules à la croissance des vaisseaux Angélique Stéphanou Bio-Informatique, Biologie Systémique [q-bio.QM]. Université Joseph-Fourier - Grenoble I, 2011 HDR tel-00749373v1

	A computational model of the spatiotemporal adaptation of tumor cells metabolism in a growing spheroid Pierre Jacquet , Angélique Stéphanou 2023 Pré-publication, Document de travail hal-04284937v1
	A biomechanical model for cell sensing and cell migration Ian Manifacier , Arnaud Chauvière , Claude Verdier , Grégory Chagnon , Ibrahim Cheddadi 2022 Pré-publication, Document de travail hal-03839909v1
	Why the tumor cell metabolism is not that abnormal Pierre Jacquet , Angélique Stéphanou 2019 Pré-publication, Document de travail hal-02402051v1

	The spatio-temporal dynamics of cell membranes deformations and cell migration Angélique Stéphanou Modeling and Simulation. Université Joseph-Fourier - Grenoble I, 2002. English. ⟨NNT : ⟩ Thèse tel-00004593v1

Angélique Stéphanou

Publications

On the Importance of Acidity in Cancer Cells and Therapy

A reduced model of cell metabolism to revisit the glycolysis-OXPHOS relationship in the deregulated tumor microenvironment

Generalization of the Ratiometric Method to Extend pH Range Measurements of the BCECF Probe

Characterization of the Intracellular Acidity Regulation of Brain Tumor Cells and Consequences for Therapeutic Optimization of Temozolomide

Searching for the Metabolic Signature of Cancer: A Review from Warburg’s Time to Now

Modelling the role of HIF in the regulation of metabolic key genes LDH and PDH: Emergence of Warburg Phenotype

Can major breakthroughs in cancer be achieved through theoretical models? Comment on “Improving cancer treatments via dynamical biophysical models” by M. Kuznetsov, J. Clairambault and V. Volpert

Metabolic Reprogramming, Questioning, and Implications for Cancer

On the importance of substrate deformations for cell migration

A minimal biomechanical model for random cell migration

HYBRID DATA-BASED MODELLING IN ONCOLOGY: SUCCESSES, CHALLENGES AND HOPES

Hybrid Modelling in Oncology: Sucesses, Challenges and Hopes

A minimal biomechanical model for random cell migration

pH as a potential therapeutic target to improve temozolomide antitumor efficacy : A mechanistic modeling study

Systems Biology, Systems Medicine, Systems Pharmacology: The What and The Why

How tumour-induced vascular changes alter angiogenesis: Insights from a computational model

Towards the Design of a Patient-Specific Virtual Tumour

Hybrid Modelling in Cell Biology

Effects of the hypoxia-mimetic agents DFO and CoCl2 on HeLa-FUCCI cells

A mathematical model of HiF-1α-mediated response to hypoxia on the G1/S transition

Proceedings of the XXXIInd Seminar of the French-Speaking Society for Theoretical Biology; Saint-Flour (Cantal), France, 10-13 June, 2012.

Mathematical modelling and numerical simulations of actin dynamics in the eukaryotic cell.

A Computational Framework to Assess the Efficacy of Cytotoxic Molecules and Vascular Disrupting Agents against Solid Tumours

On the importance of the submicrovascular network in a computational model of tumour growth.

On the Influence of Discrete Adhesive Patterns for Cell Shape and Motility: A Computational Approach

Modelling the Impact of Pericyte Migration and Coverage of Vessels on the Efficacy of Vascular Disrupting Agents

The motility of normal and cancer cells in response to the combined influence of substrate rigidity and anisotropic microstructure

Spatiotemporal dynamics of actin-rich adhesion microdomains: influence of substrate flexibility.

Spatiotemporal dynamics of actin-rich adhesion microdomains: influence of substrate flexibility

The rigidity in fibrin gels as a contributing factor to the dynamics of in vitro vascular cord formation

A mathematical model for the dynamics of large membrane deformations of isolated fibroblasts

Le vivant discret et continu - modes de représentation en biologie théorique

Spatio-temporal dynamics of the cell - characterization from images and computer-simulations

Modélisation de la motilité cellulaire perturbée par l'interaction cellule-substrat

Hybrid modelling of mechanical cues in cell migration

Reduced Model For 2D Tumor Growth and Tumor Induced Angiogenesis

Mathematical Modelling of Fibroblast shape Transition on Arrays of Adhesive Micropatterns with Varying Pitch

The Motility of Normal and Cancer Cells in Response to the Combined Influence of Substrate Rigidity and Anisotropic Nanostructure

Control of cell morphodynamic and displacement orientation by precise tuning between substrate nanopatterning and rigidity

A computational framework integrating cytoskeletal and adhesion dynamics for modelling cell motility

Une Approche Computationnelle pour l'Etude de Processus Morphogénétiques - de la motilité des cellules à la croissance des vaisseaux

A computational model of the spatiotemporal adaptation of tumor cells metabolism in a growing spheroid

A biomechanical model for cell sensing and cell migration

Why the tumor cell metabolism is not that abnormal

The spatio-temporal dynamics of cell membranes deformations and cell migration