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The HER3/ERBB3 receptor: the dark side of the ERBB planet
Christel Larbouret
,
Nadège Gaborit
,
Marie-Alix Poul
,
André Pèlegrin
,
Thierry Chardès
Article dans une revue
hal-02285139v1
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SGM-101: An innovative near-infrared dye-antibody conjugate that targets CEA for fluorescence-guided surgery
Marian Gutowski
,
Bérénice Framery
,
Martin Boonstra
,
Véronique Garambois
,
François Quenet
,
et al.
Article dans une revue
hal-02371819v1
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Llama single-domain antibodies directed against nonconventional epitopes of tumor-associated carcinoembryonic antigen absent from nonspecific cross-reacting antigen.
Ghislaine Behar
,
Patrick Chames
,
Isabelle Teulon
,
Amélie Cornillon
,
Faisal Alshoukr
,
et al.
Article dans une revue
hal-00420547v1
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Prognostic impact of epidermal growth factor receptor (EGFR) expression on loco-regional recurrence after preoperative radiotherapy in rectal cancer.
David Azria
,
Frédéric Bibeau
,
Nicolas Barbier
,
Abderrahim Zouhair
,
Claire Lemanski
,
et al.
Article dans une revue
inserm-00090458v1
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The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation
Christophe Le Clorennec
,
Yassamine Lazrek
,
Olivier Dubreuil
,
Christel Larbouret
,
Marie-Alix Poul
,
et al.
Article dans une revue
hal-02297403v1
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Symplekin promotes tumorigenicity by up-regulating claudin-2 expression
Michael Buchert
,
Marina Papin
,
Caroline Bonnans
,
Charbel Darido
,
Warren Raye
,
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2010, 107 (6), pp.2628-2633. ⟨10.1073/pnas.0903747107⟩
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hal-03108425v1
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Examination of HER3 targeting in cancer using monoclonal antibodies
Nadège Gaborit
,
Ali Abdul-Hai
,
Maicol Mancini
,
Moshit Lindzen
,
Sara Lavi
,
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (3), pp.839-844. ⟨10.1073/pnas.1423645112⟩
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hal-02276327v1
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Quantitative proteomic analysis reveals AK2 as potential biomarker for late normal tissue radiotoxicity
Jérôme Lacombe
,
Muriel Brengues
,
Alain Mangé
,
Céline Bourgier
,
Sophie Gourgou
,
et al.
Article dans une revue
hal-02371868v1
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Targets for MAbs: innovative approaches for their discovery & validation, LabEx MAbImprove 6 th antibody industrial symposium, June 25-26, 2018, Montpellier, France
Pierre Martineau
,
Herve Watier
,
André Pèlegrin
,
Andrei Turtoi
Article dans une revue
hal-02448613v1
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Apoptosis and p53 are not involved in the anti-tumor efficacy of (125)I-labeled monoclonal antibodies targeting the cell membrane.
Salomé Paillas
,
Laurent Boudou
,
Bérengère Piron
,
Nathalie Kersual
,
Manuel Bardiès
,
et al.
Article dans une revue
inserm-00815724v1
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Therapeutic Activity of Anti-AXL Antibody against Triple-Negative Breast Cancer Patient-Derived Xenografts and Metastasis
Nina Radosevic-Robin
,
Wilhem Leconet
,
Myriam Chentouf
,
Stanislas Du Manoir
,
Clément Chevalier
,
et al.
Article dans une revue
hal-01676378v1
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Improving Biologics’ Effectiveness in Clinical Oncology: From the Combination of Two Monoclonal Antibodies to Oligoclonal Antibody Mixtures
Christel Larbouret
,
Laurent Gros
,
André Pèlegrin
,
Thierry Chardès
Article dans une revue
hal-03360265v1
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Image-Guided Surgery in Patients with Pancreatic Cancer: First Results of a Clinical Trial Using SGM-101, a Novel Carcinoembryonic Antigen-Targeting, Near-Infrared Fluorescent Agent
Charlotte Hoogstins
,
Leonora Boogerd
,
Babs Sibinga Mulder
,
J. Sven D. Mieog
,
Rutger Jan Swijnenburg
,
et al.
Article dans une revue
hal-02289226v1
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Anti-HER2 vaccines: new prospects for breast cancer therapy.
Maha Zohra Ladjemi
,
William Jacot
,
Thierry Chardès
,
André Pèlegrin
,
Isabelle Navarro-Teulon
Article dans une revue
inserm-00491487v1
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[Anti-HER2 vaccines: The HER2 immunotargeting future?]
Maha-Zohra Ladjemi
,
William Jacot
,
André Pèlegrin
,
Isabelle Navarro-Teulon
Article dans une revue
inserm-00396298v1
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Toxicity and pharmacokinetic profile of SGM-101, a fluorescent anti-CEA chimeric antibody for fluorescence imaging of tumors in patients
Bérénice Framery
,
Marian Gutowski
,
Karen Dumas
,
Alexandre Evrard
,
Nathalie Muller
,
et al.
Article dans une revue
hal-02931825v1
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Dual targeting of HER1/EGFR and HER2 with cetuximab and trastuzumab in patients with metastatic pancreatic cancer after gemcitabine failure: results of the "THERAPY"phase 1-2 trial
Eric Assenat
,
David Azria
,
Caroline Mollevi
,
Rosine Guimbaud
,
Nicole Tubiana-Mathieu
,
et al.
Article dans une revue
hal-02005981v1
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Anti-tumoral activity of the Pan-HER (Sym013) antibody mixture in gemcitabine-resistant pancreatic cancer models
Emilia Rabia
,
Véronique Garambois
,
Julie Hubert
,
Marine Bruciamacchie
,
Nelly Pirot
,
et al.
Article dans une revue
hal-03360283v1
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Time-resolved fluorescence resonance energy transfer (TR-FRET) to analyze the disruption of EGFR/HER2 dimers: a new method to evaluate the efficiency of targeted therapy using monoclonal antibodies.
Nadège Gaborit
,
Christel Larbouret
,
Julie Vallaghe
,
Frédéric Peyrusson
,
Caroline Bascoul-Mollevi
,
et al.
Article dans une revue
inserm-00576598v1
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The lipid-modulating effects of a CD4-specific recombinant antibody correlate with ZAP-70 segregation outside membrane rafts.
Myriam Chentouf
,
Maxime Rigo
,
Soufiane Ghannam
,
Isabelle Navarro-Teulon
,
Sébastien Mongrand
,
et al.
Article dans une revue
inserm-00508402v1
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Redirecting NK cells mediated tumor cell lysis by a new recombinant bifunctional protein.
Claire Germain
,
Emmanuelle Campigna
,
Imed Salhi
,
Sébastien Morisseau
,
Isabelle Navarro-Teulon
,
et al.
Article dans une revue
inserm-00325786v1
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In Pancreatic Carcinoma, Dual EGFR/HER2 Targeting with Cetuximab/Trastuzumab Is More Effective than Treatment with Trastuzumab/Erlotinib or Lapatinib Alone: Implication of Receptors' Down-regulation and Dimers' Disruption.
Christel Larbouret
,
Nadège Gaborit
,
Thierry Chardès
,
Mickaël Coelho
,
Emmanuelle Campigna
,
et al.
Article dans une revue
inserm-00682017v1
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Adjuvant Radioimmunotherapy Trial with Iodine-131-Labeled Anti-Carcinoembryonic Antigen Monoclonal Antibody F6 F(ab')2 after Resection of Liver Metastases from Colorectal Cancer.
Marc Ychou
,
David Azria
,
Cathy Menkarios
,
Patrick Faurous
,
François Quenet
,
et al.
Article dans une revue
inserm-00292535v1
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A recycling anti-transferrin receptor-1 monoclonal antibody as an efficient therapy for erythroleukemia through target up-regulation and antibody-dependent cytotoxic effector functions
Madeline Neiveyans
,
Rana Melhem
,
Christophe Arnoult
,
Thomas Bourquard
,
Marta Jarlier
,
et al.
Article dans une revue
hal-02325764v1
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Anti-HER3 domain 1 and 3 antibodies reduce tumor growth by hindering HER2/HER3 dimerization and AKT-induced MDM2, XIAP, and FoxO1 phosphorylation.
Yassamine Lazrek
,
Olivier Dubreuil
,
Véronique Garambois
,
Nadège Gaborit
,
Christel Larbouret
,
et al.
Article dans une revue
inserm-00815985v1
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Higher Anti-Tumor Efficacy of the Dual HER3-EGFR Antibody MEHD7945a Combined with Ionizing Irradiation in Cervical Cancer Cells
Laura Bourillon
,
Sylvain Demontoy
,
Alexis Lenglet
,
Alexandre Zampieri
,
Julien Fraisse
,
et al.
Article dans une revue
hal-03038992v1
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Single nucleotide polymorphisms, apoptosis, and the development of severe late adverse effects after radiotherapy.
David Azria
,
Mahmut Ozsahin
,
Andrew Kramar
,
Sheila Peters
,
David P Atencio
,
et al.
Article dans une revue
inserm-00337542v1
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ITCH-dependent proteasomal degradation of c-FLIP induced by the anti-HER3 antibody 9F7-F11 promotes DR5/caspase 8-mediated apoptosis of tumor cells
Christophe Le Clorennec
,
Yassamine Lazrek
,
Olivier Dubreuil
,
Carla Sampaio
,
Christel Larbouret
,
et al.
Article dans une revue
inserm-02280785v1
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Single-domain antibody-based and linker-free bispecific antibodies targeting FcγRIII induce potent antitumor activity without recruiting regulatory T cells.
Caroline Rozan
,
Amélie Cornillon
,
Corinne Petiard
,
M. Chartier
,
G. Behar
,
et al.
Article dans une revue
hal-02454959v1
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[Bispecific antibodies: what future?]
André Pèlegrin
,
Bruno Robert
Article dans une revue
inserm-00446432v1
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