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SGM-101: An innovative near-infrared dye-antibody conjugate that targets CEA for fluorescence-guided surgery

Marian Gutowski , Bérénice Framery , Martin Boonstra , Véronique Garambois , François Quenet , et al.
Surgical Oncology, 2017, 26 (2), pp.153-162. ⟨10.1016/j.suronc.2017.03.002⟩
Article dans une revue hal-02371819v1
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The HER3/ERBB3 receptor: the dark side of the ERBB planet

Christel Larbouret , Nadège Gaborit , Marie-Alix Poul , André Pèlegrin , Thierry Chardès
Médecine/Sciences, 2015, 31 (5), pp.465-468. ⟨10.1051/medsci/20153105002⟩
Article dans une revue hal-02285139v1

Llama single-domain antibodies directed against nonconventional epitopes of tumor-associated carcinoembryonic antigen absent from nonspecific cross-reacting antigen.

Ghislaine Behar , Patrick Chames , Isabelle Teulon , Amélie Cornillon , Faisal Alshoukr , et al.
FEBS Journal, 2009, 276 (14), pp.3881-93. ⟨10.1111/j.1742-4658.2009.07101.x⟩
Article dans une revue hal-00420547v1
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The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation

Christophe Le Clorennec , Yassamine Lazrek , Olivier Dubreuil , Christel Larbouret , Marie-Alix Poul , et al.
Oncotarget, 2016, 7 (24), pp.37013-37029. ⟨10.18632/oncotarget.9455⟩
Article dans une revue hal-02297403v1
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Prognostic impact of epidermal growth factor receptor (EGFR) expression on loco-regional recurrence after preoperative radiotherapy in rectal cancer.

David Azria , Frédéric Bibeau , Nicolas Barbier , Abderrahim Zouhair , Claire Lemanski , et al.
BMC Cancer, 2005, 5, pp.62. ⟨10.1186/1471-2407-5-62⟩
Article dans une revue inserm-00090458v1

Symplekin promotes tumorigenicity by up-regulating claudin-2 expression

Michael Buchert , Marina Papin , Caroline Bonnans , Charbel Darido , Warren Raye , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2010, 107 (6), pp.2628-2633. ⟨10.1073/pnas.0903747107⟩
Article dans une revue hal-03108425v1
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Examination of HER3 targeting in cancer using monoclonal antibodies

Nadège Gaborit , Ali Abdul-Hai , Maicol Mancini , Moshit Lindzen , Sara Lavi , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (3), pp.839-844. ⟨10.1073/pnas.1423645112⟩
Article dans une revue hal-02276327v1

Targets for MAbs: innovative approaches for their discovery & validation, LabEx MAbImprove 6 th antibody industrial symposium, June 25-26, 2018, Montpellier, France

Pierre Martineau , Herve Watier , André Pèlegrin , Andrei Turtoi
mAbs, 2019, 11 (5), pp.812-825. ⟨10.1080/19420862.2019.1612691⟩
Article dans une revue hal-02448613v1

Therapeutic Activity of Anti-AXL Antibody against Triple-Negative Breast Cancer Patient-Derived Xenografts and Metastasis

Nina Radosevic-Robin , Wilhem Leconet , Myriam Chentouf , Stanislas Du Manoir , Clément Chevalier , et al.
Clinical Cancer Research, 2017, 23 (11), pp.2806 - 2816. ⟨10.1158/1078-0432.CCR-16-1316⟩
Article dans une revue hal-01676378v1
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Quantitative proteomic analysis reveals AK2 as potential biomarker for late normal tissue radiotoxicity

Jérôme Lacombe , Muriel Brengues , Alain Mangé , Céline Bourgier , Sophie Gourgou , et al.
Radiation Oncology, 2019, 14 (1), pp.142. ⟨10.1186/s13014-019-1351-8⟩
Article dans une revue hal-02371868v1
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Apoptosis and p53 are not involved in the anti-tumor efficacy of (125)I-labeled monoclonal antibodies targeting the cell membrane.

Salomé Paillas , Laurent Boudou , Bérengère Piron , Nathalie Kersual , Manuel Bardiès , et al.
Nuclear Medicine and Biology, 2013, epub ahead of print. ⟨10.1016/j.nucmedbio.2013.02.001⟩
Article dans une revue inserm-00815724v1
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Improving Biologics’ Effectiveness in Clinical Oncology: From the Combination of Two Monoclonal Antibodies to Oligoclonal Antibody Mixtures

Christel Larbouret , Laurent Gros , André Pèlegrin , Thierry Chardès
Cancers, 2021, 13 (18), pp.4620. ⟨10.3390/cancers13184620⟩
Article dans une revue hal-03360265v1

Image-Guided Surgery in Patients with Pancreatic Cancer: First Results of a Clinical Trial Using SGM-101, a Novel Carcinoembryonic Antigen-Targeting, Near-Infrared Fluorescent Agent

Charlotte Hoogstins , Leonora Boogerd , Babs Sibinga Mulder , J. Sven D. Mieog , Rutger Jan Swijnenburg , et al.
Annals of Surgical Oncology, 2018, 25 (11), pp.3350-3357. ⟨10.1245/s10434-018-6655-7⟩
Article dans une revue hal-02289226v1
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Anti-HER2 vaccines: new prospects for breast cancer therapy.

Maha Zohra Ladjemi , William Jacot , Thierry Chardès , André Pèlegrin , Isabelle Navarro-Teulon
Cancer Immunology, Immunotherapy, 2010, 59 (9), pp.1295-312. ⟨10.1007/s00262-010-0869-2⟩
Article dans une revue inserm-00491487v1
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[Anti-HER2 vaccines: The HER2 immunotargeting future?]

Maha-Zohra Ladjemi , William Jacot , André Pèlegrin , Isabelle Navarro-Teulon
Pathologie Biologie, 2009, epub ahead of print. ⟨10.1016/j.patbio.2009.04.002⟩
Article dans une revue inserm-00396298v1
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Toxicity and pharmacokinetic profile of SGM-101, a fluorescent anti-CEA chimeric antibody for fluorescence imaging of tumors in patients

Bérénice Framery , Marian Gutowski , Karen Dumas , Alexandre Evrard , Nathalie Muller , et al.
Toxicology Reports, 2019, 6, pp.409--415. ⟨10.1016/j.toxrep.2019.04.011⟩
Article dans une revue hal-02931825v1
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Dual targeting of HER1/EGFR and HER2 with cetuximab and trastuzumab in patients with metastatic pancreatic cancer after gemcitabine failure: results of the "THERAPY"phase 1-2 trial

Eric Assenat , David Azria , Caroline Mollevi , Rosine Guimbaud , Nicole Tubiana-Mathieu , et al.
Oncotarget, 2015, 6 (14), ⟨10.18632/oncotarget.3473⟩
Article dans une revue hal-02005981v1
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Anti-tumoral activity of the Pan-HER (Sym013) antibody mixture in gemcitabine-resistant pancreatic cancer models

Emilia Rabia , Véronique Garambois , Julie Hubert , Marine Bruciamacchie , Nelly Pirot , et al.
mAbs, 2021, 13 (1), pp.1914883. ⟨10.1080/19420862.2021.1914883⟩
Article dans une revue hal-03360283v1
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Cell Membrane is a More Sensitive Target than Cytoplasm to Dense Ionization Produced by Auger Electrons.

Jean-Pierre Pouget , Lore Santoro , Laure Raymond , Nicolas Chouin , Manuel Bardiès , et al.
Radiation Research, 2008, 170 (2), pp.192-200. ⟨10.1667/RR1359.1⟩
Article dans une revue inserm-00311037v1
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DNA damage-centered signaling pathways are effectively activated during low dose-rate Auger radioimmunotherapy.

Bérengère Piron , Salomé Paillas , Vincent Boudousq , André Pèlegrin , Caroline Bascoul-Mollevi , et al.
Nuclear Medicine and Biology, 2014, 41 Suppl, pp.e75-83. ⟨10.1016/j.nucmedbio.2014.01.012⟩
Article dans une revue inserm-00981411v1
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The human Mullerian inhibiting substance type II receptor as immunotherapy target for ovarian cancer. Validation using the mAb 12G4

Nathalie Kersual , Véronique Garambois , Thierry Chardès , Jean-Pierre Pouget , Imed Salhi , et al.
mAbs, 2014, 6, pp.1314--26. ⟨10.4161/mabs.29316⟩
Article dans une revue hal-02168055v1
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Brief intraperitoneal radioimmunotherapy of small peritoneal carcinomatosis using high activities of noninternalizing 125I-labeled monoclonal antibodies.

Vincent Boudousq , Stéphanie Ricaud , Véronique Garambois , Caroline Bascoul-Mollevi , Samir Boutaleb , et al.
Journal of Nuclear Medicine, 2010, 51 (11), pp.1748-55. ⟨10.2967/jnumed.110.080226⟩
Article dans une revue inserm-00531603v1
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[Bispecific antibodies: what future?]

André Pèlegrin , Bruno Robert
Médecine/Sciences, 2009, 25 (12), pp.1155-8. ⟨10.1051/medsci/200925121155⟩
Article dans une revue inserm-00446432v1

Late side-effects after curative intent radiotherapy: Identification of hypersensitive patients for personalized strategy

Céline Bourgier , Jérôme Lacombe , Jérôme Solassol , Alain Mangé , André Pèlegrin , et al.
Critical Reviews in Oncology/Hematology, 2015, 93 (3), pp.312-319. ⟨10.1016/j.critrevonc.2014.11.004⟩
Article dans une revue hal-02148578v1
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Radiation-induced CD8 T-lymphocyte Apoptosis as a Predictor of Breast Fibrosis After Radiotherapy: Results of the Prospective Multicenter French Trial

David Azria , Olivier Riou , Florence Castan , Tan Dat Nguyen , Karine Peignaux , et al.
EBioMedicine, 2015, 2 (12), pp.1965-1973. ⟨10.1016/j.ebiom.2015.10.024⟩
Article dans une revue hal-02338826v1

Synthesis of new cyclic RGD peptides for specific tumor cell targeting.

Florine Cavelier , Julien Schmidt , Luc Rocheblave , Jean Martinez , André Pèlegrin , et al.
Peptides, 2006, pp.600
Article dans une revue hal-00117023v1
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Noninternalizing monoclonal antibodies are suitable candidates for 125I radioimmunotherapy of small-volume peritoneal carcinomatosis.

Lore Santoro , Samir Boutaleb , Véronique Garambois , Caroline Bascoul-Mollevi , Vincent Boudousq , et al.
Journal of Nuclear Medicine, 2009, 50 (12), pp.2033-41. ⟨10.2967/jnumed.109.066993⟩
Article dans une revue inserm-00442929v1
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The anti-tumor efficacy of 3C23K, a glyco-engineered humanized anti-MISRII antibody, in an ovarian cancer model is mainly mediated by engagement of immune effector cells

Pauline Estupina , Alexandre Fontayne , Jean-Marc Barret , Nathalie Kersual , Olivier Dubreuil , et al.
Oncotarget, 2017, 8 (23), pp.37061-37079. ⟨10.18632/oncotarget.15715⟩
Article dans une revue hal-02379710v1
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Single-domain antibody-based and linker-free bispecific antibodies targeting FcγRIII induce potent antitumor activity without recruiting regulatory T cells.

Caroline Rozan , Amélie Cornillon , Corinne Petiard , M. Chartier , G. Behar , et al.
Molecular Cancer Therapeutics, 2013, 12 (8), pp.1481-1491. ⟨10.1158/1535-7163.MCT-12-1012⟩
Article dans une revue hal-02454959v1
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Peptides in Receptor-Mediated Radiotherapy: From Design to the Clinical Application in Cancers

Catherine Lozza , Isabelle Navarro-Teulon , André Pèlegrin , Jean-Pierre Pouget , Eric Vivès
Frontiers in Oncology, 2013, 3 (2), pp.332. ⟨10.3389/fonc.2013.00247⟩
Article dans une revue hal-03824440v1