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Structure analysis uncovers a highly diverse but structurally conserved effector family in phytopathogenic fungi

Karine de Guillen , Diana Ortiz-Vallero , Jérôme Gracy , Elisabeth E. Fournier , Thomas T. Kroj , et al.
PLoS Pathogens, 2015, 11 (10), pp.e1005228. ⟨10.1371/journal.ppat.1005228⟩
Article dans une revue hal-02634260v1
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N (6)-substituted AMPs inhibit mammalian deoxynucleotide N-hydrolase DNPH1.

Claire Amiable , Sylvie Pochet , André Padilla , Gilles Labesse , Pierre-Alexandre Kaminski
PLoS ONE, 2013, 8 (11), pp.e80755. ⟨10.1371/journal.pone.0080755.t003⟩
Article dans une revue pasteur-01472730v1
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HIV-1 Nef protein: Purification, crystallizations, and preliminary X-ray diffraction studies

P. Franken , S. Arold , André Padilla , M Bodeus , F. Hoh , et al.
Protein Science, 1997, 6, pp.2681 - 2683. ⟨10.1002/pro.5560061227⟩
Article dans une revue hal-02359698v1

NMR structure of rALF-Pm3, an anti-lipopolysaccharide factor from shrimp: Model of the possible lipid A-binding site.

Yinshan Yang , Hélène Boze , Patrick Chemardin , André Padilla , Guy Moulin , et al.
Biopolymers, 2009, 91 (3), pp.207-20. ⟨10.1002/bip.21119⟩
Article dans une revue hal-00358510v1
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Structural genomics applied to the rust fungus Melampsora larici-populina reveals two candidate effector proteins adopting cystine knot and NTF2-like protein folds

Karine de Guillen , Cécile Lorrain , Pascale Tsan , Philippe Barthe , Benjamin Petre , et al.
Scientific Reports, 2019, 9 (1), pp.18084. ⟨10.1038/s41598-019-53816-9⟩
Article dans une revue hal-02548559v1
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1H, 13C, 15 N backbone and side-chain NMR assignments for three MAX effectors from Magnaporthe oryzae

Mounia Lahfa , André Padilla , Karine de Guillen , Joana Pissarra , Mouna Raji , et al.
Biomolecular NMR Assignments, 2022, 16 (2), pp.305-309. ⟨10.1007/s12104-022-10095-2⟩
Article dans une revue hal-04234517v1
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Structure Structural insights into the allosteric activation of the LicT antiterminator by PTS- mediated phosphorylation

Yinshan Yang , André Padilla , Karine de Guillen , Léa Mammri , Jérôme Gracy , et al.
Structure, 2020, 28 (2), pp.244-251.e3. ⟨10.1016/j.str.2019.10.017⟩
Article dans une revue hal-02368196v1

Structural Insight into the Mycobacterium tuberculosis Rv0020c Protein and Its Interaction with the PknB Kinase

Christian Roumestand , Jade Leiba , Nathalie Galophe , Emmanuel Margeat , André Padilla , et al.
Structure, 2011, 19 (10), pp.1525-1534. ⟨10.1016/j.str.2011.07.011⟩
Article dans une revue hal-02282715v1
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Structural and Biochemical Characterization of the Cop9 Signalosome CSN5/CSN6 Heterodimer

Melissa Birol , Radoslav Ivanov Enchev , André Padilla , Florian Stengel , Ruedi Aebersold , et al.
PLoS ONE, 2014, 9 (8), pp.e105688. ⟨10.1371/journal.pone.0105688⟩
Article dans une revue hal-02359383v1

Biochemical characterization of the helper component of Cauliflower mosaic virus

Eugénie Hébrard , M. Drucker , D. Leclerc , T. Hohn , Marilyne Uzest , et al.
Journal of Virology, 2001, 75 (18), pp.8538-8546
Article dans une revue hal-02674872v1

Stylin-1, the first protein located in the acrostyle and its role in non-circulative virus transmission by aphids

Craig Webster , François Hoh , Manuella van Munster , Daniel Gargani , André Padilla , et al.
8. Rencontres du réseau Biologie Adaptative des Pucerons et Organismes Associés (BAPOA), Nov 2015, Paris, France
Communication dans un congrès hal-02794212v1

6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: synthesis, structural studies and cytotoxic activities.

Claire Amiable , Julie Paoletti , Ahmed Haouz , André Padilla , Gilles Labesse , et al.
European Journal of Medicinal Chemistry, 2014, 85, pp.418-37. ⟨10.1016/j.ejmech.2014.07.110⟩
Article dans une revue pasteur-01483767v1
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Combining High-Pressure NMR and Geometrical Sampling to Obtain a Full Topological Description of Protein Folding Landscapes: Application to the Folding of Two MAX Effectors from Magnaporthe oryzae

Cécile Dubois , Mounia Lahfa , Joana Pissarra , Karine de Guillen , Philippe Barthe , et al.
International Journal of Molecular Sciences, 2022, 23 (10), pp.5461. ⟨10.3390/ijms23105461⟩
Article dans une revue hal-03705665v1

The preliminary solution structure of human p13 MTCPI an oncogenic protein encoded by the MTCPI gene, using 2D homonuclear NMR

Laurent Guignard , Y.-S Yang , André Padilla , C. Boiteau , M.-P Strub , et al.
Journal de Chimie Physique, 1998, 1, pp.454 - 459. ⟨10.1051/jcp:1998116⟩
Article dans une revue istex hal-02359634v1

Structure-based discovery of an inhibitor of Arf activation by Sec7 domains through targeting of protein-protein complexes.

Julien Viaud , Mahel Zeghouf , Hélène Barelli , Jean-Christophe Zeeh , André Padilla , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2007, 104 (25), pp.10370-5. ⟨10.1073/pnas.0700773104⟩
Article dans une revue hal-03726712v1

Removing the invariant salt bridge of parvalbumin increases flexibility in the AB -loop structure

François Hoh , Adrien Cavé , Marie-Paule Strub , Jean-Louis Banères , André Padilla
Acta crystallographica Section D : Structural biology [1993-..], 2009, 65 (8), pp.733-743. ⟨10.1107/S0907444909011482⟩
Article dans une revue istex hal-02359417v1

Fragment-Based Identification of a Locus in the Sec7 Domain of Arno for the Design of Protein-Protein Interaction Inhibitors.

Jad Rouhana , Francois Hoh , Sébastien Estaran , Corinne Henriquet , Yvan Boublik , et al.
Journal of Medicinal Chemistry, 2013, 56 (8497−8511), epub ahead of print. ⟨10.1021/jm4009357⟩
Article dans une revue hal-03726698v1
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Specific recognition of two MAX effectors by integrated HMA domains in plant immune receptors involves distinct binding surfaces

Liwei Guo , Stella S. Cesari , Karine de Guillen , Véronique Chalvon , Léa Mammri , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (45), pp.11637-11642. ⟨10.1073/pnas.1810705115⟩
Article dans une revue hal-02349802v1

Structural Insight into the Mycobacterium tuberculosis Rv0020c Protein and Its Interaction with the PknB Kinase

Christian Roumestand , Jade Leiba , Nathalie Galophe , Emmanuel Margeat , André Padilla , et al.
Structure, 2011, 19 (10), pp.1525-1534. ⟨10.1016/j.str.2011.07.011⟩
Article dans une revue hal-03726704v1

Solution structure of the recombinant human oncoprotein p13 MTCP1

Yin-Shan Yang , Laurent Guignard , André Padilla , François Hoh , Marie-Paule Strub , et al.
Journal of Biomolecular NMR, 1998, 11 (3), pp.337 - 354. ⟨10.1023/A:1008279616063⟩
Article dans une revue istex hal-02359642v1
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Does a Similar 3D Structure Mean a Similar Folding Pathway? The Presence of a C-Terminal α-Helical Extension in the 3D Structure of MAX60 Drastically Changes the Folding Pathway Described for Other MAX-Effectors from Magnaporthe oryzae

Mounia Lahfa , Assia Mouhand , Karine De de Guillen , Philippe Barthe , Thomas Kroj , et al.
Molecules, 2023, 28 (16), pp.6068. ⟨10.3390/molecules28166068⟩
Article dans une revue hal-04234553v1
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The structural landscape and diversity of Pyricularia oryzae MAX effectors revisited

Mounia Lahfa , Philippe Barthe , Karine De Guillen , Stella Cesari , Mouna Raji , et al.
2023
Pré-publication, Document de travail hal-04236508v1

The activity of the RGA5 sensor NLR from rice requires binding of its integrated HMA domain to effectors but not HMA domain self‐interaction

Yuxuan Xi , Véronique Chalvon , André Padilla , Stella Cesari , Thomas Kroj
Molecular Plant Pathology, In press, ⟨10.1111/mpp.13236⟩
Article dans une revue hal-03720934v1
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Aedesin: Structure and Antimicrobial Activity against Multidrug Resistant Bacterial Strains

Sylvain Godreuil , Nadia Leban , André Padilla , Rodolphe Hamel , Natthanej Luplertlop , et al.
PLoS ONE, 2014, 9 (8), pp.e105441. ⟨10.1371/journal.pone.0105441⟩
Article dans une revue hal-01358388v1

Fragment-Based Identification of a Locus in the Sec7 Domain of Arno for the Design of Protein-Protein Interaction Inhibitors.

Jad Rouhana , Francois Hoh , Sébastien Estaran , Corinne Henriquet , Yvan Boublik , et al.
Journal of Medicinal Chemistry, 2013, 56 (8497−8511), epub ahead of print. ⟨10.1021/jm4009357⟩
Article dans une revue hal-00905451v1

NMR structure of rALF-Pm3, an anti-lipopolysaccharide factor from shrimp: Model of the possible lipid A-binding site.

Yinshan Yang , Hélène Boze , Patrick Chemardin , André Padilla , Guy Moulin , et al.
Biopolymers, 2009, 91 (3), pp.207-20. ⟨10.1002/bip.21119⟩
Article dans une revue hal-03726710v1
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Structural characterization of the mammalian deoxynucleotide N-hydrolase Rcl and its stabilizing interactions with two inhibitors.

Yinshan Yang , André Padilla , Chi Zhang , Gilles Labesse , Pierre-Alexandre Kaminski
Journal of Molecular Biology, 2009, 394 (3), pp.435-47. ⟨10.1016/j.jmb.2009.10.004⟩
Article dans une revue istex pasteur-00432797v1

Crystal structure of P4tcl1, an oncogene product involved in T-cell prolymphocytic leukemia, reveals a nolve beta-barrel topology

François Hoh , Yin-Shan Yang , Laurent Guignard , André Padilla , Marc-Henri Stern , et al.
Article dans une revue hal-02359625v1
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Recognition of the Magnaporthe oryzae effector AVR-Pia by the decoy domain of the rice NLR immune receptor RGA5

Diana Ortiz , Karine de Guillen , Stella Cesari , Veronique Chalvon-Poulier , Jérôme Gracy , et al.
The Plant cell, 2017, 29 (1), pp.156-168. ⟨10.1105/tpc.16.00435⟩
Article dans une revue hal-01608403v1
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New recognition specificity in a plant immune receptor by molecular engineering of its integrated domain

Thomas Kroj , André Padilla , Vincent Chochois , Karine de Guillen , Corinne Henriquet , et al.
Nature Communications, 2022, 13 (1), pp.1524. ⟨10.1038/s41467-022-29196-6⟩
Article dans une revue hal-03646871v1