Aline THOMAS

Documents

Publications

	Toward non-factor therapy in hemophilia: an antithrombin insensitive Gla-domainless factor Xa as tissue factor pathway inhibitor bait Marie-Claire Dagher , Atanur Ersayin , Landry Seyve , Mathieu Castellan , Cyril Moreau Research and Practice in Thrombosis and Haemostasis, 2023, 7 (6), pp.102175. ⟨10.1016/j.rpth.2023.102175⟩ Article dans une revue hal-04235785v1
	An in vitro model to assess the peripheral vestibulotoxicity of aromatic solvents Running title: In vitro screening of aromatic solvent vestibulotoxicity V. Tallandier , M. Chalansonnet , L. Merlen , S. Boucard , Aline Thomas NeuroToxicology, 2021, ⟨10.1016/j.neuro.2021.03.002⟩ Article dans une revue hal-03176306v1
	Interest of novel N-alkylpyridinium-indolizine hybrids in the field of Alzheimer's disease: Synthesis, characterization and evaluation of antioxidant activity, cholinesterase inhibition, and amyloid fibrillation interference Isabelle Baussanne , Olga Firstovaa , Andreea Botezatu Dediu , Camille Larosa , Bianca Furdui Bioorganic Chemistry, 2021, 116, pp.105390. ⟨10.1016/j.bioorg.2021.105390⟩ Article dans une revue hal-03365026v2
	Could we expect new praziquantel derivatives ? A meta pharmacometrics/pharmacoinformatics analysis of all antischistosomal praziquantel derivatives found in the literature V.B. Ribeiro da Silva , B. Boucherle , J. El-Methni , B. Hoffmann , A.L. da Silva SAR and QSAR in Environmental Research, 2019, 30 (6), pp.383 - 401. ⟨10.1080/1062936X.2019.1607898⟩ Article dans une revue hal-03928621v1
	Chimeric Protein–Protein Interface Inhibitors Allow Efficient Inhibition of Type III Secretion Machinery and Pseudomonas aeruginosa Virulence Tuan-Dung Ngo , Sophie Plé , Aline Thomas , Caroline Barette , Antoine Fortuné ACS Infectious Diseases, 2019, 5 (11), pp.1843-1854. ⟨10.1021/acsinfecdis.9b00154⟩ Article dans une revue hal-02318760v1
	Rapid discovery of de novo deleterious mutations in cattle enhances the value of livestock as model species Emmanuelle Bourneuf , P. Otz , H. Pausch , V. Jagannathan , Pauline Michot Scientific Reports, 2017, 7 (1), pp.11466. ⟨10.1038/s41598-017-11523-3⟩ Article dans une revue hal-01608270v1
	Catalytically inactive Gla-domainless factor Xa binds to TFPI and restores ex vivo coagulation in hemophilia plasma Atanur Ersayin , Aline Thomas , Landry Seyve , Nicole M. Thielens , Mathieu Castellan Haematologica, 2017, 102 (12), pp.e483 - e485. ⟨10.3324/haematol.2017.174037⟩ Article dans une revue hal-01657794v1
	Catalytically inactive Gla-domainless factor Xa binds to TFPI and restores ex vivo coagulation in hemophilia plasma Atanur Ersayin , Aline Thomas , Landry Seyve , Nicole M. Thielens , Mathieu Castellan Haematologica, 2017, 102 (12), pp.e483-e485. ⟨10.3324/haematol.2017.174037⟩ Article dans une revue hal-03068097v1
	Structural insights and membrane binding properties of MGD1, the major galactolipid synthase in plants Joana Rocha , Joe Sarkis , Aline Thomas , Laurence Pitou , Jens Radzimanowski Plant Journal, 2016, 85 (5), pp.622-633. ⟨10.1111/tpj.13129⟩ Article dans une revue hal-01272198v1
	Langerin–heparin interaction: two binding sites for small and large ligands as revealed by a combination of NMR spectroscopy and cross-linking mapping experiments Juan Muñoz-García , Eric Chabrol , Romain Vivès , Aline Thomas , José de Paz Journal of the American Chemical Society, 2015, 137 (12), pp.4100-4110. ⟨10.1021/ja511529x⟩ Article dans une revue hal-03754287v1
	Langerin–Heparin Interaction: Two Binding Sites for Small and Large Ligands As Revealed by a Combination of NMR Spectroscopy and Cross-Linking Mapping Experiments Juan Muñoz-García , Eric Chabrol , Romain Vivès , Aline Thomas , José de Paz Journal of the American Chemical Society, 2015, 137 (12), pp.4100-4110. ⟨10.1021/ja511529x⟩ Article dans une revue hal-03752769v1
	Probing the Acceptor Active Site Organization of the Human Recombinant beta 1,4-Galactosyltransferase 7 and Design of Xyloside-based Inhibitors Mineem Saliba , Nick Ramalanjaona , Sandrine Gulberti , Isabelle Bertin-Jung , Aline Thomas Journal of Biological Chemistry, 2015, 290 (12), pp.7658-7670. ⟨10.1074/jbc.M114.628123⟩ Article dans une revue hal-01451902v1
	Langerin-heparin interaction: two binding sites for small and large ligands as revealed by a combination of NMR spectroscopy and cross-linking mapping experiments. Juan C Muñoz-García , Eric Chabrol , Romain R Vivès , Aline Thomas , José L de Paz Journal of the American Chemical Society, 2015, 137 (12), pp.4100-10 Article dans une revue hal-01149071v1
	Visceral white fat remodelling contributes to intermittent hypoxia-induced atherogenesis L. Poulain , A. Thomas , Jennifer Rieusset , L. Casteilla , P. Levy European Respiratory Journal, 2014, 43 (2), pp.513-522. ⟨10.1183/09031936.00019913⟩ Article dans une revue hal-01859545v1
	Reduction of Lectin Valency Drastically Changes Glycolipid Dynamics in Membranes but Not Surface Avidity Julie Arnaud , Julie Claudinon , Kevin Tröndle , Marie Trovaslet , Göran Larson ACS Chemical Biology, 2013, 8 (9), pp.1918-1924. ⟨10.1021/cb400254b⟩ Article dans une revue hal-03068212v1
	Insights into the Mechanism by Which Interferon-γ Basic Amino Acid Clusters Mediate Protein Binding to Heparan Sulfate. Els Saesen , Stéphane Sarrazin , Cédric Laguri , Rabia Sadir , Damien Maurin Journal of the American Chemical Society, 2013, 135 (25), pp.9384-90. ⟨10.1021/ja4000867⟩ Article dans une revue hal-00847973v1
	Deciphering the Glycan Preference of Bacterial Lectins by Glycan Array and Molecular Docking with Validation by Microcalorimetry and Crystallography Jeremie Topin , Julie Arnaud , Anita Sarkar , Aymeric Audfray , Emilie Gillon PLoS ONE, 2013, pp.e71149. ⟨10.1371/journal.pone.0071149⟩ Article dans une revue hal-03068180v1
	Some Key Features to Consider When Studying Acrylamide-Based Polymers for Chemical Enhanced Oil Recovery A. Thomas , N. Gaillard , C. Favero Oil & Gas Science and Technology - Revue d'IFP Energies nouvelles, 2012, 67 (6), pp.887-902. ⟨10.2516/ogst/2012065⟩ Article dans une revue hal-01936538v1
	Transglutaminase-2 Interaction with Heparin: IDENTIFICATION OF A HEPARIN BINDING SITE THAT REGULATES CELL ADHESION TO FIBRONECTIN-TRANSGLUTAMINASE-2 MATRIX. Hugues Lortat-Jacob , Izhar Burhan , Alessandra Scarpellini , Aline Thomas , Anne Imberty Journal of Biological Chemistry, 2012, 287 (22), pp.18005-17. ⟨10.1074/jbc.M111.337089⟩ Article dans une revue hal-00718061v1
	Discovery of New Inhibitors of Resistant Streptococcus pneumoniae Penicillin Binding Protein (PBP) 2x by Structure-Based Virtual Screening Laurence Miguet , Astrid Zervosen , Thomas Gerards , Farhan Pasha , André Luxen Journal of Medicinal Chemistry, 2009, 52 (19), pp.5926-5936. ⟨10.1021/jm900625q⟩ Article dans une revue hal-03068184v1
	An implementation of the nudged elastic band algorithm and application to the reaction mechanism of HGXPRTase from Plasmodium falciparum Ramon Crehuet , Aline Thomas , Martin Field Journal of Molecular Graphics and Modelling, 2005, 24 (2), pp.102-110. ⟨10.1016/j.jmgm.2005.05.003⟩ Article dans une revue hal-03068222v1
	An implementation of the nudged elastic band algorithm and application to the reaction mechanism of HGXPRTase from Plasmodium falciparum Laurent Mugherli , Olga n. Burchak , Larissa a. Balakireva , Aline Thomas , François Chatelain Journal of Molecular Graphics and Modelling, 2005, 24 (2), pp.102-110. ⟨10.1016/j.jmgm.2005.05.003⟩ Article dans une revue hal-03068232v1
	Reaction Mechanism of the HGXPRTase from Plasmodium f alciparum : A Hybrid Potential Quantum Mechanical/Molecular Mechanical Study Aline Thomas , Martin Field Journal of the American Chemical Society, 2002, 124 (42), pp.12432-12438. ⟨10.1021/ja0206846⟩ Article dans une revue hal-03068235v1
	Analysis of domain motions in large proteins Konrad Hinsen , Aline Thomas , Martin Field Proteins: Structure, Function, and Genetics, 1999, 34 (3), pp.369-382. ⟨10.1002/(SICI)1097-0134(19990215)34:3<369::AID-PROT9>3.0.CO;2-F⟩ Article dans une revue hal-02159761v1
	Tertiary and quaternary conformational changes in aspartate transcarbamylase: a normal mode study D. Thomas , Konrad Hinsen , Martin Field , David Perahia , Aline Thomas Proteins: Structure, Function, and Genetics, 1999, 34 (1), pp.96-112. ⟨10.1002/(SICI)1097-0134(19990101)34:1<96::AID-PROT8>3.0.CO;2-0⟩ Article dans une revue hal-02159763v1
	Is There a Covalent Intermediate in the Viral Neuraminidase Reaction? A Hybrid Potential Free-Energy Study Aline Thomas , David Jourand , Celine Bret , Patricia Amara , Martin Field Journal of the American Chemical Society, 1999, 121 (41), pp.9693-9702. ⟨10.1021/ja991603h⟩ Article dans une revue hal-03068194v1
	Structural Basis of Antibody Cross-Reactivity: Solution Conformation of an Immunogenic Peptide Fragment Containing both T and B Epitopes Philippe Cuniasse , Aline Thomas , Jeremy Smith , Hung Lam Thanh , Michel Leonetti Biochemistry, 1995, 34 (39), pp.12782-12789. ⟨10.1021/bi00039a039⟩ Article dans une revue hal-03068252v1
	Engineering of protein epitopes: a single deletion in a snake toxin generates full binding capacity to a previously unrecognized antibody Sophie Zinn-Justin , Laurence Pillet , Frédéric Ducancel , Aline Thomas , Jeremy Smith Protein Engineering, Design and Selection, 1994, 7 (7), pp.917-923. ⟨10.1093/protein/7.7.917⟩ Article dans une revue hal-03068254v1
	Computer simulations of the flexibility of a series of synthetic cyclic peptide analogues Aline Thomas , Benoît Roux , Jeremy Smith Biopolymers, 1993, 33 (8), pp.1249-1270. ⟨10.1002/bip.360330811⟩ Article dans une revue hal-03068258v1
	Symmetry and crystallography: New facilities in the graphic software MANOSK Aline Thomas , M.C. Vaney , M. Le Bars , J.P. Mornon , I. Morize Journal of Molecular Graphics, 1990, 8 (2), pp.108-110. ⟨10.1016/0263-7855(90)80090-3⟩ Article dans une revue hal-03068245v1
	Hydrophobic cluster analysis (HCA) of the hormone-binding domain of receptor proteins J.P. Mornon , V. Bissery , C. Gaboriaud , Aline Thomas , T. Ojasoo Journal of Steroid Biochemistry, 1989, 34 (1-6), pp.355-361. ⟨10.1016/0022-4731(89)90108-8⟩ Article dans une revue hal-03068249v1

	Arthralgies et éruption acrale : une forme bruyante de syndrome post-streptococcique peu connu, l’acrovésiculopustulose L. Cavée , A.M. Blind , M. Groza , A. Thomas , J. Cattelan 77e congrès de médecine interne, Jun 2018, Lyon, France. 39, pp.A165-A166, 2018, ⟨10.1016/j.revmed.2018.03.113⟩ Poster de conférence hal-02182614v1

	Composés pour le traitement de l’hémophilie Aline Thomas , Marie Claire Dagher , Muriel Jourdan , Benoit Polack , Raphaël Marlu France, Patent n° : FR 2007806. 2020 Brevet hal-03068374v1
	Leurre GD-FXa mutant Aline Thomas , Raphaël Marlu , Benoit Polack , Atanur Ersayin , Marie Claire Dagher France, Patent n° : FR1753060. 2017 Brevet hal-03068391v1
	Facteur X dépourvu de domain GLA Marie Claire Dagher , Benoit Polack , Raphaël Marlu , Aline Thomas France, Patent n° : PCT/FR2012/05425. 2013 Brevet hal-03068411v1
	Protocoagulant pour hémophile Benoit Polack , Aline Thomas France, Patent n° : FR11/51637. 2011 Brevet hal-03068417v1

	Does Corporate Social Responsibility strengthen social dialogue ? Nicolas Poussing , A. Thomas , Valérie Swaen RIODD, Quelles responsabilités pour les entreprises ?, Oct 2017, Paris, France. 2017 Proceedings/Recueil des communications hal-02615211v1

	Structure-function study of MGD1, the major galactolipid synthase in Arabidopsis Joana Rocha , Laurence Pitou , Aline Thomas , Maryse Block , Eric Maréchal Annual Conference of the Society for Glycobiology, Society for glycobiology., Nov 2013, St. Petersburg, United States Communication dans un congrès hal-02748574v1
	Quantitative analysis of particle shape during grinding : application to hydrargillite T. Rolland , Marie-Noëlle Pons , A. Thomas , Hervé Vivier , John A. Dodds 5th World congress of chemical engineering -Technologies critical to a changing world, Jul 1996, San Diego, United States. p.271-276 Communication dans un congrès hal-01808942v1
	Fragmentation by high velocity impacts on a target Olivier Lecoq , N. Chouteau , P. Guignon , A. Rolland , Marie-Noëlle Pons 7TH WORLD FILTRATION CONGRESS, Jun 1996, Nancy, France Communication dans un congrès hal-01809141v1
	Regulation of nonpoint source pollution when factor augmentation of polluting inputs is possible A. Thomas , Robert D. Weaver 8. Congress : Redefining the roles for European agriculture, Sep 1996, Edimbourg, United Kingdom. 25 p Communication dans un congrès hal-02299647v1

	Rationally designed Gla-domainless FXa as TFPI bait in hemophilia Marie-Claire Dagher , Atanur Ersayin , Landry Seyve , Mathieu Castellan , Cyril Moreau 2022 Pré-publication, Document de travail hal-03774924v1

Aline THOMAS

Publications

Toward non-factor therapy in hemophilia: an antithrombin insensitive Gla-domainless factor Xa as tissue factor pathway inhibitor bait

An in vitro model to assess the peripheral vestibulotoxicity of aromatic solvents Running title: In vitro screening of aromatic solvent vestibulotoxicity

Interest of novel N-alkylpyridinium-indolizine hybrids in the field of Alzheimer's disease: Synthesis, characterization and evaluation of antioxidant activity, cholinesterase inhibition, and amyloid fibrillation interference

Could we expect new praziquantel derivatives ? A meta pharmacometrics/pharmacoinformatics analysis of all antischistosomal praziquantel derivatives found in the literature

Chimeric Protein–Protein Interface Inhibitors Allow Efficient Inhibition of Type III Secretion Machinery and Pseudomonas aeruginosa Virulence

Rapid discovery of de novo deleterious mutations in cattle enhances the value of livestock as model species

Catalytically inactive Gla-domainless factor Xa binds to TFPI and restores ex vivo coagulation in hemophilia plasma

Catalytically inactive Gla-domainless factor Xa binds to TFPI and restores ex vivo coagulation in hemophilia plasma

Structural insights and membrane binding properties of MGD1, the major galactolipid synthase in plants

Langerin–heparin interaction: two binding sites for small and large ligands as revealed by a combination of NMR spectroscopy and cross-linking mapping experiments

Langerin–Heparin Interaction: Two Binding Sites for Small and Large Ligands As Revealed by a Combination of NMR Spectroscopy and Cross-Linking Mapping Experiments

Probing the Acceptor Active Site Organization of the Human Recombinant beta 1,4-Galactosyltransferase 7 and Design of Xyloside-based Inhibitors

Langerin-heparin interaction: two binding sites for small and large ligands as revealed by a combination of NMR spectroscopy and cross-linking mapping experiments.

Visceral white fat remodelling contributes to intermittent hypoxia-induced atherogenesis

Reduction of Lectin Valency Drastically Changes Glycolipid Dynamics in Membranes but Not Surface Avidity

Insights into the Mechanism by Which Interferon-γ Basic Amino Acid Clusters Mediate Protein Binding to Heparan Sulfate.

Deciphering the Glycan Preference of Bacterial Lectins by Glycan Array and Molecular Docking with Validation by Microcalorimetry and Crystallography

Some Key Features to Consider When Studying Acrylamide-Based Polymers for Chemical Enhanced Oil Recovery

Transglutaminase-2 Interaction with Heparin: IDENTIFICATION OF A HEPARIN BINDING SITE THAT REGULATES CELL ADHESION TO FIBRONECTIN-TRANSGLUTAMINASE-2 MATRIX.

Discovery of New Inhibitors of Resistant Streptococcus pneumoniae Penicillin Binding Protein (PBP) 2x by Structure-Based Virtual Screening

An implementation of the nudged elastic band algorithm and application to the reaction mechanism of HGXPRTase from Plasmodium falciparum

An implementation of the nudged elastic band algorithm and application to the reaction mechanism of HGXPRTase from Plasmodium falciparum

Reaction Mechanism of the HGXPRTase from Plasmodium f alciparum : A Hybrid Potential Quantum Mechanical/Molecular Mechanical Study

Analysis of domain motions in large proteins

Tertiary and quaternary conformational changes in aspartate transcarbamylase: a normal mode study

Is There a Covalent Intermediate in the Viral Neuraminidase Reaction? A Hybrid Potential Free-Energy Study

Structural Basis of Antibody Cross-Reactivity: Solution Conformation of an Immunogenic Peptide Fragment Containing both T and B Epitopes

Engineering of protein epitopes: a single deletion in a snake toxin generates full binding capacity to a previously unrecognized antibody

Computer simulations of the flexibility of a series of synthetic cyclic peptide analogues

Symmetry and crystallography: New facilities in the graphic software MANOSK

Hydrophobic cluster analysis (HCA) of the hormone-binding domain of receptor proteins

Arthralgies et éruption acrale : une forme bruyante de syndrome post-streptococcique peu connu, l’acrovésiculopustulose

Composés pour le traitement de l’hémophilie

Leurre GD-FXa mutant

Facteur X dépourvu de domain GLA

Protocoagulant pour hémophile

Does Corporate Social Responsibility strengthen social dialogue ?

Structure-function study of MGD1, the major galactolipid synthase in Arabidopsis

Quantitative analysis of particle shape during grinding : application to hydrargillite

Fragmentation by high velocity impacts on a target

Regulation of nonpoint source pollution when factor augmentation of polluting inputs is possible

Rationally designed Gla-domainless FXa as TFPI bait in hemophilia