Number of documents

24

Alice Lebreton, Group leader, INRA CR1, HDR

Research career

Since 2015	Group leader, Institute of Biology of École normale supérieure (IBENS), Paris, HDR.
2008-2014	INRA Research scientist (CR1), Pasteur Institute (lab P. Cossart, group H. Bierne), Paris.
2006-2008	Post-doctoral fellow, Centre de Génétique Moléculaire (lab B. Séraphin), CNRS, Gif-sur-Yvette.
2002-2006	PhD thesis student, Pasteur Institute (lab A. Jacquier, supervision M. Fromont-Racine), Paris.
2000	Intern, Microbiology Institute (lab Th. Leisinger), ETH Zürich.
1999	Summer intern, La Pitié-Salpêtrière hospital, Paris.

Teaching

Currently	Lecturer for the biology department of École normale supérieure. Organisation of the Molecular Cell Biology course for non-biologist students at ENS (Bachelor’s degree), co-organisation of the Microbial Systems course, (IMaLiS Master’s degree). Lecturer at ENS Cachan for the Cell Biology of Host-Invasive Bacteria Interactions course (Master’s degree).
2002-2005	Teaching assistant in Immunology (Bachelor’s degree), Paris 7 University.

Education

2002-2006	PhD in Microbiology-Virology, Paris 7 University.
1998-2002	Studies in Biochemistry and Cell Biology at École normale supérieure de Cachan and Paris 7 University. Undergraduate studies in Biochemistry and Cell Biology, then Master’s degree in Microbiology-Virology (Pasteur Institute). Agrégation (French degree for high-school teaching) in Biochemistry – Biological Engineering.

Journal articles23 documents

Mathieu Bahin, Benoit Noel, Valentine Murigneux, Charles Bernard, Leila Bastianelli, et al.. ALFA: annotation landscape for aligned reads. BMC Genomics, BioMed Central, 2019, 20 (250), ⟨https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-019-5624-2⟩. ⟨10.1186/s12864-019-5624-2⟩. ⟨hal-02084432⟩
Mélodie Duval, Pascale Cossart, Alice Lebreton. Mammalian microRNAs and long noncoding RNAs in the host-bacterial pathogen crosstalk. Seminars in Cell and Developmental Biology, Elsevier, 2017, 65, pp.11-19. ⟨http://linkinghub.elsevier.com/retrieve/pii/S1084952116301628⟩. ⟨10.1016/j.semcdb.2016.06.016⟩. ⟨hal-01350977⟩
Alice Lebreton, Pascale Cossart. RNA- and protein-mediated control of Listeria monocytogenes virulence gene expression. RNA Biology, Taylor & Francis, 2017, 14 (5), pp.460-470. ⟨10.1080/15476286.2016.1189069⟩. ⟨hal-01350979⟩
Alice Lebreton, Fabrizia Stavru, Sylvain Brisse, Pascale Cossart. 1926–2016: 90 Years of listeriology. Microbes and Infection, Elsevier, 2016, 18 (12), pp.711 - 723. ⟨http://www.sciencedirect.com/science/article/pii/S128645791630168X⟩. ⟨10.1016/j.micinf.2016.10.009⟩. ⟨hal-01400517⟩
Goran Lakisic, Alice Lebreton, Renaud Pourpre, Olivia Wendling, Emanuele Libertini, et al.. Role of the BAHD1 Chromatin-Repressive Complex in Placental Development and Regulation of Steroid Metabolism. PLoS Genetics, Public Library of Science, 2016, 12 (3), pp.e1005898. ⟨http://dx.plos.org/10.1371/journal.pgen.1005898⟩. ⟨10.1371/journal.pgen.1005898⟩. ⟨hal-01350966⟩
Alice Lebreton, Fabrizia Stavru, Pascale Cossart. Organelle targeting during bacterial infection: insights from Listeria. Trends in Cell Biology, Elsevier, 2015, 25 (6), pp.330-8. ⟨10.1016/j.tcb.2015.01.003⟩. ⟨pasteur-01162370⟩
Emanuele Libertini, Alice Lebreton, Goran Lakisic, Marie-Agnès Dillies, Stephan Beck, et al.. Overexpression of the Heterochromatinization Factor BAHD1 in HEK293 Cells Differentially Reshapes the DNA Methylome on Autosomes and X Chromosome. Frontiers in Genetics, Frontiers, 2014, 6, pp.339. ⟨http://journal.frontiersin.org/article/10.3389/fgene.2015.00339/full⟩. ⟨10.3389/fgene.2015.00339⟩. ⟨hal-01350961⟩
Alice Lebreton, Viviana Job, Marie Ragon, Alban Le Monnier, Andréa Dessen, et al.. Structural basis for the inhibition of the chromatin repressor BAHD1 by the bacterial nucleomodulin LntA.. mBio, American Society for Microbiology, 2014, 5 (1), pp.e00775-13. ⟨10.1128/mBio.00775-13⟩. ⟨hal-01109386⟩
Pascale Cossart, Alice Lebreton. A trip in the "New Microbiology" with the bacterial pathogen Listeria monocytogenes. FEBS Letters, Wiley, 2014, 588 (15), pp.2437-45. ⟨10.1016/j.febslet.2014.05.051⟩. ⟨pasteur-01161887⟩
Alice Lebreton, Pascale Cossart, Hélène Bierne. Bacteria tune interferon responses by playing with chromatin. VIRULENCE, 2012, 3 (1), pp.87-91. ⟨10.4161/viru.3.1.18531⟩. ⟨hal-01350803⟩
Hélène Bierne, Laetitia Travier, Tanel Mahlakõiv, Ludovic Tailleux, Agathe Subtil, et al.. Activation of type III interferon genes by pathogenic bacteria in infected epithelial cells and mouse placenta.. PLoS ONE, Public Library of Science, 2012, 7 (6), pp.e39080. ⟨10.1371/journal.pone.0039080⟩. ⟨pasteur-00750162⟩
Cristel Archambaud, Odile Sismeiro, Joern Toedling, Guillaume Soubigou, Christophe Bécavin, et al.. The intestinal microbiota interferes with the microRNA response upon oral Listeria infection.. mBio, American Society for Microbiology, 2012, 4 (6), pp.e00707-13. ⟨10.1128/mBio.00707-13⟩. ⟨hal-01350904⟩
Alice Lebreton, Helene Bierne, Pascale Cossart. Les multiples stratégies de Listeria. Pour la science, Pour la science, 2012, 412, pp.42-49. ⟨https://www.pourlascience.fr/sd/biologie-cellulaire/les-multiples-strategies-de-ilisteriai-6626.php⟩. ⟨hal-01204374⟩
Rajani Kanth Gudipati, Zhenyu Xu, Alice Lebreton, Bertrand Séraphin, Lars M Steinmetz, et al.. Extensive degradation of RNA precursors by the exosome in wild-type cells.. Molecular Cell, Elsevier, 2012, 48 (3), pp.409-21. ⟨10.1016/j.molcel.2012.08.018⟩. ⟨hal-01350901⟩
Alice Lebreton, Goran Lakisic, Viviana Job, Lauriane Fritsch, To Nam Tham, et al.. A bacterial protein targets the BAHD1 chromatin complex to stimulate type III interferon response. Science, American Association for the Advancement of Science, 2011, 331 (6022), pp.1319-21. ⟨http://www.sciencemag.org/cgi/doi/10.1126/science.1200120⟩. ⟨10.1126/science.1200120⟩. ⟨cea-00819299⟩
Alice Lebreton, Bertrand Séraphin. Exosome-mediated quality control: substrate recruitment and molecular activity. BBA - Biochimica et Biophysica Acta, Elsevier, 2008, 1779 (9), pp.558-65. ⟨http://www.sciencedirect.com.gate2.inist.fr/science/article/pii/S187493990800045X⟩. ⟨10.1016/j.bbagrm.2008.02.003⟩. ⟨hal-01350691⟩
Alice Lebreton, Jean-Claude Rousselle, Pascal Lenormand, Abdelkader Namane, Alain Jacquier, et al.. 60S ribosomal subunit assembly dynamics defined by semi-quantitative mass spectrometry of purified complexes. Nucleic Acids Research, Oxford University Press, 2008, 36 (15), pp.4988-4999. ⟨10.1093/nar/gkn469⟩. ⟨hal-01350774⟩
Alice Lebreton, Rafal Tomecki, Andrzej Dziembowski, Bertrand Séraphin. Endonucleolytic RNA cleavage by a eukaryotic exosome. Nature, Nature Publishing Group, 2008, 456 (7224), pp.993-6. ⟨http://www.nature.com/nature/journal/v456/n7224/full/nature07480.html⟩. ⟨10.1038/nature07480⟩. ⟨hal-01350769⟩
Brigitte Pertschy, Cosmin Saveanu, Gertrude Zisser, Alice Lebreton, Martin Tengg, et al.. Cytoplasmic recycling of 60S preribosomal factors depends on the AAA protein Drg1. Molecular and Cellular Biology, American Society for Microbiology, 2007, 27 (19), pp.6581-92. ⟨http://mcb.asm.org.gate2.inist.fr/content/27/19/6581.long⟩. ⟨10.1128/MCB.00668-07⟩. ⟨hal-01350677⟩
Alice Lebreton, Cosmin Saveanu, Laurence Decourty, Alain Jacquier, Micheline Fromont-Racine. Nsa2 is an unstable, conserved factor required for the maturation of 27 SB pre-rRNAs. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2006, 281 (37), pp.27099-108. ⟨http://jcb.rupress.org/content/173/3/349.long⟩. ⟨10.1074/jbc.M602199200⟩. ⟨hal-01350676⟩
Alice Lebreton, Cosmin Saveanu, Laurence Decourty, Jean-Christophe Rain, Alain Jacquier, et al.. A functional network involved in the recycling of nucleocytoplasmic pre-60S factors. Journal of Cell Biology, Rockefeller University Press, 2006, 173 (3), pp.349-60. ⟨http://jcb.rupress.org/content/173/3/349.long⟩. ⟨10.1083/jcb.200510080⟩. ⟨hal-01350674⟩
Cosmin Saveanu, Abdelkader Namane, Pierre-Emmanuel Gleizes, Alice Lebreton, Jean-Claude Rousselle, et al.. Sequential protein association with nascent 60S ribosomal particles. Molecular and Cellular Biology, American Society for Microbiology, 2003, 23 (13), pp.4449-60. ⟨http://mcb.asm.org/cgi/doi/10.1128/MCB.23.13.4449-4460.2003⟩. ⟨10.1128/MCB.23.13.4449–4460.2003⟩. ⟨hal-01350680⟩
Susana de Azevedo Wäsch, Jan van der Ploeg, Tere Maire, Alice Lebreton, Andreas Kiener, et al.. Transformation of isopropylamine to L-alaninol by Pseudomonas sp. strain KIE171 involves N-glutamylated intermediates. Applied and Environmental Microbiology, American Society for Microbiology, 2002, 68 (5), pp.2368-75. ⟨10.1128/AEM.68.5.2368–23750.2002⟩. ⟨hal-01350667⟩

Theses1 document

Alice Lebreton. Dynamique des facteurs pré-ribosomiques au cours de la biogenèse de la grande sous-unité ribosomique chez S. cerevisiae. Biochimie [q-bio.BM]. Université Paris-Diderot - Paris VII, 2006. Français. ⟨tel-00100381⟩