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THY-Tau22 mouse model accumulates more tauopathy at late stage of the disease in response to microglia deactivation through TREM2 deficiency

Audrey Vautheny , Charlotte Duwat , Gwennaëlle Aurégan , Charlène Joséphine , Anne-Sophie Hérard , et al.
Neurobiology of Disease, 2021, 155, pp.105398. ⟨10.1016/j.nbd.2021.105398⟩
Article dans une revue inserm-03366724v1
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IGF-1 exacerbates the neurotoxicity of the mitochondrial inhibitor 3NP in rats

Carole Escartin , Frédéric Boyer , Alexis-Pierre Bemelmans , Philippe Hantraye , Emmanuel Brouillet
Neuroscience Letters, 2007, 425 (3), pp.167-172. ⟨10.1016/j.neulet.2007.08.031⟩
Article dans une revue cea-02290618v1
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Thérapie génique du système nerveux central: Considérations générales sur les vecteurs viraux pour le transfert de gène dans le cerveau

Ché Serguera , Alexis-Pierre Bemelmans
Revue Neurologique, 2014, 170 (12), pp.727-738. ⟨10.1016/j.neurol.2014.09.004⟩
Article dans une revue cea-03650651v1

Characterization of the striatal kinase Dclk3 and its neuroprotective effects against mutant huntingtin

E. Brouillet , L. Francelle , Laurie Galvan , M.-C Gaillard , M.-A Carrillo-de Sauvage , et al.
SFN 2015, Oct 2015, CHICAGO, United States
Communication dans un congrès hal-02534708v1

Nanoscale molecular architecture controls calcium diffusion and ER replenishment in dendritic spines

Kanishka Basnayake , David Mazaud , Lilia Kushnireva , Alexis Bemelmans , Nathalie Rouach , et al.
Science Advances , 2021, 7 (38), ⟨10.1126/sciadv.abh1376⟩
Article dans une revue hal-03516891v1
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The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin

Laurie Galvan , Laetitia Francelle , Marie-Claude Gaillard , Lucie de Longprez , Maria-Angeles Carrillo-de Sauvage , et al.
Brain - A Journal of Neurology , 2018, 141 (5), pp.1434-1454. ⟨10.1093/brain/awy057⟩
Article dans une revue hal-02074093v1
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TLR9 activation via microglial glucocorticoid receptors contributes to degeneration of midbrain dopamine neurons

Layal Maatouk , Anne-Claire Compagnion , Maria-Angeles Carrillo-De Sauvage , Alexis-Pierre Bemelmans , Sabrina Leclere-Turbant , et al.
Nature Communications, 2018, 9, pp.2450. ⟨10.1038/s41467-018-04569-y⟩
Article dans une revue cea-01881325v1

An adenovirus encoding CuZnSOD protects cultured striatal neurones against glutamate toxicity

Martine Barkats , Alexis-Pierre Bemelmans , Marie-Claude Geoffroy , Jean-Jacques Robert , Isabelle Loquet , et al.
NeuroReport, 1996, 7 (2), pp.497-501. ⟨10.1097/00001756-199601310-00029⟩
Article dans une revue hal-03083413v1

Lentiviral-mediated gene transfer of brain-derived neurotrophic factor is neuroprotective in a mouse model of neonatal excitotoxic challenge.

Alexis-Pierre Bemelmans , Isabelle Husson , Muriel Jaquet , Jacques Mallet , Barry E Kosofsky , et al.
Journal of Neuroscience Research, 2006, 83 (1), pp.50-60. ⟨10.1002/jnr.20704⟩
Article dans une revue istex hal-00166667v1
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Physiological synaptic activity and recognition memory require astroglial glutamine

Giselle Cheung , Danijela Bataveljic , Josien Visser , Naresh Kumar , Julien Moulard , et al.
Nature Communications, 2022, 13 (1), pp.753. ⟨10.1038/s41467-022-28331-7⟩
Article dans une revue hal-03625240v1
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Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration

Olivier Levy , Bertrand Calippe , Sophie Lavalette , Shulong J Hu , William Raoul , et al.
EMBO Molecular Medicine, 2015, 7 (2), pp.211-26. ⟨10.15252/emmm.201404524⟩
Article dans une revue inserm-01231055v1
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Impairment of Glycolysis-Derived l-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer’s Disease

Juliette Le Douce , Marianne Maugard , Julien Veran , Marco Matos , Pierrick Jégo , et al.
Cell Metabolism, 2020, 31 (3), pp.503-517.e8. ⟨10.1016/j.cmet.2020.02.004⟩
Article dans une revue hal-02989009v2
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Potentiating tangle formation reduces acute toxicity of soluble tau species in the rat

Marie D’orange , Gwenaëlle Auregan , Dimitri Cheramy , Mylène Gaudin-Guérif , Sarah Lieger , et al.
Brain - A Journal of Neurology , 2018, 141 (2), pp.535-549. ⟨10.1093/brain/awx342⟩
Article dans une revue cea-02074052v1
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Complex roles for reactive astrocytes in the triple transgenic mouse model of Alzheimer disease

Océane Guillemaud , Kelly Ceyzériat , Thomas Saint-Georges , Karine Cambon , Fanny Petit , et al.
2019
Pré-publication, Document de travail cea-02392438v1
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Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer’s disease

Kelly Ceyzériat , Lucile Ben Haim , Audrey Denizot , Dylan Pommier , Marco Matos , et al.
Acta Neuropathologica Communications, 2018, 6 (1), pp.1047. ⟨10.1186/s40478-018-0606-1⟩
Article dans une revue hal-02074082v1

Chromatic serial multiphoton microscopy for multicolor imaging of large brain volumes

Lamiae Abdeladim , Katherine S. Matho , Solène Clavreul , Pierre Mahou , Jean-Marc Sintes , et al.
Advances in Microscopic Imaging, Proceedings of SPIE, the International Society for Optical Engineering, SPIE, pp.7, 2019, ⟨10.1117/12.2526947⟩
Proceedings/Recueil des communications hal-02372159v1

Functional reinnervation from remaining DA terminals induced by GDNF lentivirus in a rat model of early Parkinson's disease.

Mara Brizard , Carole Carcenac , Alexis-Pierre Bemelmans , Claude Feuerstein , Jacques Mallet , et al.
Neurobiology of Disease, 2006, 21 (1), pp.90-101. ⟨10.1016/j.nbd.2005.06.015⟩
Article dans une revue istex hal-00166668v1
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rAAV-mediated cochlear gene therapy: Prospects and challenges for clinical application

Fabian Blanc , Michel Mondain , Alexis-Pierre Bemelmans , Corentin Affortit , Jean-Luc Puel , et al.
Journal of Clinical Medicine, 2020, 9 (2), pp.589. ⟨10.3390/jcm9020589⟩
Article dans une revue hal-03521743v1

βAPP Processing Drives Gradual Tau Pathology in an Age-Dependent Amyloid Rat Model of Alzheimer’s Disease

Mickael Audrain , Benoit Souchet , Sandro Alves , Romain Fol , Arthur Viodé , et al.
Cerebral Cortex, 2018, 28 (11), pp.3976-3993. ⟨10.1093/cercor/bhx260⟩
Article dans une revue hal-02324980v1

PKCδ-positive GABAergic neurons in the central amygdala exhibit tissue-type plasminogen activator: role in the control of anxiety

Sara Douceau , Eloïse Lemarchand , Yannick Hommet , Laurent Lebouvier , Charlène Joséphine , et al.
Molecular Psychiatry, 2022, 27 (4), pp.2197-2205. ⟨10.1038/s41380-022-01455-4⟩
Article dans une revue hal-04444779v1
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Local Translation in Perisynaptic Astrocytic Processes Is Specific and Changes after Fear Conditioning

Noémie Mazaré , Marc Oudart , Julien Moulard , Giselle Cheung , Romain Tortuyaux , et al.
Cell Reports, 2020, 32, ⟨10.1016/j.celrep.2020.108076⟩
Article dans une revue hal-03013688v1
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A new promoter allows optogenetic vision restoration with enhanced sensitivity in macaque retina

Antoine Chaffiol , Romain P Caplette , Céline Jaillard , Elena Brazhnikova , Mélissa Desrosiers , et al.
Molecular Therapy, 2017, 25 (11), pp.2546-2560. ⟨10.1016/j.ymthe.2017.07.011⟩
Article dans une revue hal-01844782v1

The C-Terminal Domain of LRRK2 with the G2019S Substitution Increases Mutant A53T α-Synuclein Toxicity in Dopaminergic Neurons In Vivo

Noémie Cresto , Camille Gardier , Marie-Claude Gaillard , Francesco Gubinelli , Pauline Roost , et al.
International Journal of Molecular Sciences, 2021, 22 (13), pp.6760. ⟨10.3390/ijms22136760⟩
Article dans une revue hal-03452142v1

Repair of Rhodopsin mRNA by Spliceosome-Mediated RNA Trans -Splicing: A New Approach for Autosomal Dominant Retinitis Pigmentosa

Adeline Berger , Stéphanie Lorain , Charlène Joséphine , Mélissa Desrosiers , Cécile Peccate , et al.
Molecular Therapy, 2015, 23 (5), pp.918-930. ⟨10.1038/mt.2015.11⟩
Article dans une revue cea-02155559v1
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Alzheimer's disease-like APP processing in wild-type mice identifies synaptic defects as initial steps of disease progression.

Mickael Audrain , Romain Fol , Patrick Dutar , Brigitte Potier , Jean-Marie Billard , et al.
Molecular Neurodegeneration, 2016, 11 (1), pp.5. ⟨10.1186/s13024-016-0070-y⟩
Article dans une revue inserm-01322473v1

Targeted in vivo expression of nicotinic acetylcholine receptors in mouse brain using lentiviral expression vectors.

B. E. Molles , Uwe Maskos , Stéphane Pons , M. Besson , Bruno P. Guiard , et al.
Journal of Molecular Neuroscience, 2006, 30 (1-2), pp.105-6. ⟨10.1385/JMN:30:1:105⟩
Article dans une revue istex pasteur-00161355v1
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Spectral-domain optical coherence tomography of the rodent eye: highlighting layers of the outer retina using signal averaging and comparison with histology.

Adeline Berger , Sophie Cavallero , Elisa Dominguez , Peggy Barbe , Manuel Simonutti , et al.
PLoS ONE, 2014, 9 (5), pp.e96494. ⟨10.1371/journal.pone.0096494⟩
Article dans une revue hal-00990132v1

Deciphering the molecular basis of invasiveness in Sdhb-deficient cells

Céline Loriot , Mélanie Domingues , Adeline Berger Berger , Mélanie Menara , Maëva Ruel , et al.
Oncotarget, 2016, 6 (32), pp.32955-32965. ⟨10.18632/oncotarget.5106⟩
Article dans une revue hal-01373908v1
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Hyperactivation of retina by light in mice leads to photoreceptor cell death mediated by VEGF and retinal pigment epithelium permeability

M Cachafeiro , Alexis-Pierre Bemelmans , M Samardzija , T Afanasieva , J-A Pournaras , et al.
Cell Death and Disease, 2013, 4, pp.e781. ⟨10.1038/cddis.2013.303⟩
Article dans une revue hal-01548456v1

mRNA trans -splicing in gene therapy for genetic diseases

Adeline Berger , Séverine Maire , Marie-Claude Gaillard , José-Alain Sahel , Philippe Hantraye , et al.
Wiley Interdisciplinary Reviews: RNA, 2016, 7 (4), pp.487-498. ⟨10.1002/wrna.1347⟩
Article dans une revue cea-02073831v1