Recherche - Archive ouverte HAL Accéder directement au contenu

Filtrer vos résultats

48 résultats
Page :
triés par
Image document

THY-Tau22 mouse model accumulates more tauopathy at late stage of the disease in response to microglia deactivation through TREM2 deficiency

 Audrey Vautheny , Charlotte Duwat , Gwennaëlle Aurégan , Charlène Joséphine , Anne-Sophie Hérard , et al.
Neurobiology of Disease, 2021, 155, pp.105398. ⟨10.1016/j.nbd.2021.105398⟩
Article dans une revue inserm-03366724v1
Image document

IGF-1 exacerbates the neurotoxicity of the mitochondrial inhibitor 3NP in rats

 Carole Escartin , Frédéric Boyer , Alexis-Pierre Bemelmans , Philippe Hantraye , Emmanuel Brouillet
Neuroscience Letters, 2007, 425 (3), pp.167-172. ⟨10.1016/j.neulet.2007.08.031⟩
Article dans une revue cea-02290618v1
Image document

Thérapie génique du système nerveux central: Considérations générales sur les vecteurs viraux pour le transfert de gène dans le cerveau

 Ché Serguera , Alexis-Pierre Bemelmans
Revue Neurologique, 2014, 170 (12), pp.727-738. ⟨10.1016/j.neurol.2014.09.004⟩
Article dans une revue cea-03650651v1

Nanoscale molecular architecture controls calcium diffusion and ER replenishment in dendritic spines

 Kanishka Basnayake , David Mazaud , Lilia Kushnireva , Alexis Bemelmans , Nathalie Rouach , et al.
Science Advances , 2021, 7 (38), ⟨10.1126/sciadv.abh1376⟩
Article dans une revue hal-03516891v1

Characterization of the striatal kinase Dclk3 and its neuroprotective effects against mutant huntingtin

 E. Brouillet , L. Francelle , Laurie Galvan , M.-C Gaillard , M.-A Carrillo-de Sauvage , et al.
SFN 2015, Oct 2015, CHICAGO, United States
Communication dans un congrès hal-02534708v1
Image document

The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin

 Laurie Galvan , Laetitia Francelle , Marie-Claude Gaillard , Lucie de Longprez , Maria-Angeles Carrillo-de Sauvage , et al.
Brain - A Journal of Neurology , 2018, 141 (5), pp.1434-1454. ⟨10.1093/brain/awy057⟩
Article dans une revue hal-02074093v1
Image document

TLR9 activation via microglial glucocorticoid receptors contributes to degeneration of midbrain dopamine neurons

 Layal Maatouk , Anne-Claire Compagnion , Maria-Angeles Carrillo-De Sauvage , Alexis-Pierre Bemelmans , Sabrina Leclere-Turbant , et al.
Nature Communications, 2018, 9, pp.2450. ⟨10.1038/s41467-018-04569-y⟩
Article dans une revue cea-01881325v1
Image document

Potentiating tangle formation reduces acute toxicity of soluble tau species in the rat

 Marie D’orange , Gwenaëlle Auregan , Dimitri Cheramy , Mylène Gaudin-Guérif , Sarah Lieger , et al.
Brain - A Journal of Neurology , 2018, 141 (2), pp.535-549. ⟨10.1093/brain/awx342⟩
Article dans une revue cea-02074052v1
Image document

Complex roles for reactive astrocytes in the triple transgenic mouse model of Alzheimer disease

 Océane Guillemaud , Kelly Ceyzériat , Thomas Saint-Georges , Karine Cambon , Fanny Petit , et al.
2019
Pré-publication, Document de travail cea-02392438v1

Chromatic serial multiphoton microscopy for multicolor imaging of large brain volumes

 Lamiae Abdeladim , Katherine S. Matho , Solène Clavreul , Pierre Mahou , Jean-Marc Sintes , et al.
Advances in Microscopic Imaging, Proceedings of SPIE, the International Society for Optical Engineering, SPIE, pp.7, 2019, ⟨10.1117/12.2526947⟩
Proceedings/Recueil des communications hal-02372159v1
Image document

Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer’s disease

 Kelly Ceyzériat , Lucile Ben Haim , Audrey Denizot , Dylan Pommier , Marco Matos , et al.
Acta Neuropathologica Communications, 2018, 6 (1), pp.1047. ⟨10.1186/s40478-018-0606-1⟩
Article dans une revue hal-02074082v1
Image document

Impairment of Glycolysis-Derived l-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer’s Disease

 Juliette Le Douce , Marianne Maugard , Julien Veran , Marco Matos , Pierrick Jégo , et al.
Cell Metabolism, 2020, 31 (3), pp.503-517.e8. ⟨10.1016/j.cmet.2020.02.004⟩
Article dans une revue hal-02989009v2

An adenovirus encoding CuZnSOD protects cultured striatal neurones against glutamate toxicity

 Martine Barkats , Alexis-Pierre Bemelmans , Marie-Claude Geoffroy , Jean-Jacques Robert , Isabelle Loquet , et al.
NeuroReport, 1996, 7 (2), pp.497-501. ⟨10.1097/00001756-199601310-00029⟩
Article dans une revue hal-03083413v1
Image document

Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration

 Olivier Levy , Bertrand Calippe , Sophie Lavalette , Shulong J Hu , William Raoul , et al.
EMBO Molecular Medicine, 2015, 7 (2), pp.211-26. ⟨10.15252/emmm.201404524⟩
Article dans une revue inserm-01231055v1

Lentiviral-mediated gene transfer of brain-derived neurotrophic factor is neuroprotective in a mouse model of neonatal excitotoxic challenge.

 Alexis-Pierre Bemelmans , Isabelle Husson , Muriel Jaquet , Jacques Mallet , Barry E Kosofsky , et al.
Journal of Neuroscience Research, 2006, 83 (1), pp.50-60. ⟨10.1002/jnr.20704⟩
Article dans une revue istex hal-00166667v1
Image document

Physiological synaptic activity and recognition memory require astroglial glutamine

 Giselle Cheung , Danijela Bataveljic , Josien Visser , Naresh Kumar , Julien Moulard , et al.
Nature Communications, 2022, 13 (1), pp.753. ⟨10.1038/s41467-022-28331-7⟩
Article dans une revue hal-03625240v1
Image document

A new promoter allows optogenetic vision restoration with enhanced sensitivity in macaque retina

 Antoine Chaffiol , Romain P Caplette , Céline Jaillard , Elena Brazhnikova , Mélissa Desrosiers , et al.
Molecular Therapy, 2017, 25 (11), pp.2546-2560. ⟨10.1016/j.ymthe.2017.07.011⟩
Article dans une revue hal-01844782v1
Image document

rAAV-mediated cochlear gene therapy: Prospects and challenges for clinical application

 Fabian Blanc , Michel Mondain , Alexis-Pierre Bemelmans , Corentin Affortit , Jean-Luc Puel , et al.
Journal of Clinical Medicine, 2020, 9 (2), pp.589. ⟨10.3390/jcm9020589⟩
Article dans une revue hal-03521743v1
Image document

Local Translation in Perisynaptic Astrocytic Processes Is Specific and Changes after Fear Conditioning

 Noémie Mazaré , Marc Oudart , Julien Moulard , Giselle Cheung , Romain Tortuyaux , et al.
Cell Reports, 2020, 32, ⟨10.1016/j.celrep.2020.108076⟩
Article dans une revue hal-03013688v1

Functional reinnervation from remaining DA terminals induced by GDNF lentivirus in a rat model of early Parkinson's disease.

 Mara Brizard , Carole Carcenac , Alexis-Pierre Bemelmans , Claude Feuerstein , Jacques Mallet , et al.
Neurobiology of Disease, 2006, 21 (1), pp.90-101. ⟨10.1016/j.nbd.2005.06.015⟩
Article dans une revue istex hal-00166668v1

PKCδ-positive GABAergic neurons in the central amygdala exhibit tissue-type plasminogen activator: role in the control of anxiety

 Sara Douceau , Eloïse Lemarchand , Yannick Hommet , Laurent Lebouvier , Charlène Joséphine , et al.
Molecular Psychiatry, 2022, 27 (4), pp.2197-2205. ⟨10.1038/s41380-022-01455-4⟩
Article dans une revue hal-04444779v1

βAPP Processing Drives Gradual Tau Pathology in an Age-Dependent Amyloid Rat Model of Alzheimer’s Disease

 Mickael Audrain , Benoit Souchet , Sandro Alves , Romain Fol , Arthur Viodé , et al.
Cerebral Cortex, 2018, 28 (11), pp.3976-3993. ⟨10.1093/cercor/bhx260⟩
Article dans une revue hal-02324980v1

Loss of otx2 in the adult retina disrupts retinal pigment epithelium function, causing photoreceptor degeneration.

 Michael Housset , Alexander Samuel , Mohamed Ettaiche , Alexis-Pierre Bemelmans , Francis Béby , et al.
Journal of Neuroscience, 2013, 33 (24), pp.9890-904. ⟨10.1523/JNEUROSCI.1099-13.2013⟩
Article dans une revue hal-00843349v1

Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors.

 Uwe Maskos , B. E. Molles , Stéphane Pons , M. Besson , Bruno Guiard , et al.
Nature, 2005, 436 (7047), pp.103-7. ⟨10.1038/nature03694⟩
Article dans une revue istex pasteur-00162546v1

Fast calcium transients in dendritic spines driven by extreme statistics

 Kanishka Basnayake , David Mazaud , Alexis Bemelmans , Nathalie Rouach , Eduard Korkotian , et al.
PLoS Biology, 2019, 17 (6), pp.e2006202. ⟨10.1371/journal.pbio.2006202⟩
Article dans une revue hal-02626523v1
Image document

The Small Molecule Alpha-Synuclein Aggregator, FN075, Enhances Alpha-Synuclein Pathology in Subclinical AAV Rat Models

 Rachel Kelly , Andrew G Cairns , Jörgen Ådén , Fredrik Almqvist , Alexis-Pierre Bemelmans , et al.
Biomolecules, 2021, 11 (11), pp.1685. ⟨10.3390/biom11111685⟩
Article dans une revue hal-04444836v1
Image document

The C-terminal domain of LRRK2 with the G2019S mutation is sufficient to produce neurodegeneration of dopaminergic neurons in vivo

 Noémie Cresto , Marie-Claude Gaillard , Camille Gardier , Francesco Gubinelli , Elsa Diguet , et al.
Neurobiology of Disease, 2020, 134, pp.104614. ⟨10.1016/j.nbd.2019.104614⟩
Article dans une revue hal-03043360v1

Insulin growth factor-1 protects against excitotoxicity in the rat striatum

 Carole Escartin , Frédéric Boyer , Alexis-Pierre Bemelmans , Philippe Hantraye , Emmanuel Brouillet
NeuroReport, 2004, 15 (14), pp.2251-2254. ⟨10.1097/00001756-200410050-00022⟩
Article dans une revue cea-02290615v1
Image document

The intellectual disability protein Oligophrenin1 controls astrocyte morphology and migration

 Laure-Elise Pillet , Noémie Cresto , Yoann Saillour , Grégory Ghézali , Alexis-Pierre Bemelmans , et al.
Glia, 2020, Epub ahead of print. ⟨10.1002/glia.23801⟩
Article dans une revue inserm-02506646v1
Image document

A Single Intravenous AAV9 Injection Mediates Bilateral Gene Transfer to the Adult Mouse Retina

 Alexis-Pierre Bemelmans , Sandra Duqué , Christel Rivière , Stéphanie Astord , Mélissa Desrosiers , et al.
PLoS ONE, 2013, 8 (4), pp.e61618. ⟨10.1371/journal.pone.0061618⟩
Article dans une revue hal-01537691v1
Page :