Number of documents

18

Dr. Alexandre VASSEUR


Professional experience:

Since Oct. 2018
Research assistant professor at CNRS (Chargé de Recherche au CNRS). Appointment in the University of Lorraine/Lorraine Laboratory of Molecular Chemistry, CNRS UMR 7053.Research axis: Heterocycles and Functional Materials (HeMaF).
 
2015-2018 (3 years)
Teaching and Research Temporary Attaché at the Institute of Molecular Sciences of Marseille, CNRS UMR 7313/Ecole Centrale de Marseille.
Advisors: Dr. D. NUEL, Dr. L. GIORDANO & Prof. Dr. A. MARTINEZ
Topic: Synthesis of chiral supramolecular bisphosphinite palladacycles and applications in organic synthesis.
 
2013-2015 (2 years 6 months)
Post-doctoral associate at Technion – Israel Institute of Technology, Haifa, Israel (European Research Council financial support).
Advisor: Prof. Ilan MAREK,Sir Michael & Lady Sobell Academic Chair.
Topic: Transition metal-assisted remote functionalization of alkenes.

Teaching experience:

2015-2018
Teaching in the first and second years of engineering school (Ecole Centrale de Marseille) – 558 h ETD
Structure and molecular properties (1st year): tutorials (48 h); Molecular reactivity (1st year): tutorials (70 h) and practical work (416 h); Materials (2nd year): practical work (24 h).

Education:

2012
PhD degree in organic chemistry with highest honors (CNRS BDI fellowship) at the Reims Institute of Molecular Chemistry – ICMR, CNRS UMR 7312/University of Reims.
Advisor: Dr. Jean LE BRAS.
Topic: C-H Functionalization of heterocycles derived from biomass:  Pd-catalyzed dehydrogenative Heck reactions.
Committee members: Prof. Jean-Cyrille HIERSO (University of Burgundy), Prof. Jérôme WASER (Federal Polytechnic School of Lausanne), Dr. Nicolas RABASSO (University of Paris XI), Dr. Norbert Hoffmann (University of Reims), Dr. Jacques MUZART (University of Reims), Dr. Jean LE BRAS (University of Reims).
 
2009
Master degree in molecular chemistry with distinction - University of Reims (School of pharmacy).
Master degree placement: Reims Institute of Molecular Chemistry (ICMR), CNRS UMR 7312/University of Reims
Advisor: Prof. Dominique GUILLAUME.
Topic: Synthesis of enantiopure Beyrepel® analogues, repellents for mosquitoes.


Journal articles16 documents

  • Romain Membrat, Alexandre Vasseur, Laurent Giordano, Alexandre Martinez, Didier Nuel. General methodology for the chemoselective N-alkylation of (2,2,6,6)-tetramethylpiperidin-4-ol: Contribution of microwave irradiation. Tetrahedron Letters, Elsevier, 2019, 60 (3), pp.240-243. ⟨10.1016/j.tetlet.2018.12.020⟩. ⟨hal-01969189⟩
  • Romain Membrat, Alexandre Vasseur, Alexandre Martinez, Laurent Giordano, Didier Nuel. Phosphinous Acid Platinum Complex as Robust Catalyst for Oxidation: Comparison with Palladium and Mechanistic Investigations. European Journal of Organic Chemistry, Wiley-VCH Verlag, 2018, 2018 (39), pp.5427-5434. ⟨10.1002/ejoc.201801040⟩. ⟨hal-01905995⟩
  • Jeffrey Bruffaerts, Alexandre Vasseur, Sukhdev Singh, Ahmad Masarwa, Dorian Didier, et al.. Zirconocene-Mediated Selective C–C Bond Cleavage of Strained Carbocycles: Scope and Mechanism. Journal of Organic Chemistry, American Chemical Society, 2018, 83 (7), pp.3497 - 3515. ⟨10.1021/acs.joc.7b03115⟩. ⟨hal-01767301⟩
  • Alexandre Vasseur, Romain Membrat, Davide Palpacelli, Michel Giorgi, Didier Nuel, et al.. Synthesis of chiral supramolecular bisphosphinite palladacycles through hydrogen transfer-promoted self-assembly process. Chemical Communications, Royal Society of Chemistry, 2018, 54 (72), pp.10132 - 10135. ⟨10.1039/c8cc06283h⟩. ⟨hal-01870774⟩
  • Jeffrey Bruffaerts, Alexandre Vasseur, Ilan Marek. Alkene-Zipper Catalyzed Selective and Remote Retro-ene Reaction of Alkenyl Cyclopropylcarbinol. Advanced Synthesis and Catalysis, Wiley-VCH Verlag, 2018, 360 (7), pp.1389 - 1396. ⟨10.1002/adsc.201701481⟩. ⟨hal-01780966⟩
  • Alexandre Vasseur, Romain Membrat, David Gatineau, Alphonse Tenaglia, Didier Nuel, et al.. Secondary Phosphine Oxides as Multitalented Preligands En Route to the Chemoselective Palladium-Catalyzed Oxidation of Alcohols. ChemCatChem, Wiley, 2017, 9 (5), pp.728 - 732. ⟨10.1002/cctc.201601261⟩. ⟨hal-01682727⟩
  • Sukhdev Singh, Jeffrey Bruffaerts, Alexandre Vasseur, Ilan Marek. A unique Pd-catalysed Heck arylation as a remote trigger for cyclopropane selective ring-opening. Nature Communications, Nature Publishing Group, 2017, 8, ⟨10.1038/ncomms14200⟩. ⟨hal-01780964⟩
  • Alexandre Vasseur, Ilan Marek. Merging allylic C–H bond activation and C–C bond cleavage en route to the formation of a quaternary carbon stereocenter in acyclic systems. Nature Protocols, Nature Publishing Group, 2016, 12 (1), pp.74 - 87. ⟨10.1038/nprot.2016.161⟩. ⟨hal-01780962⟩
  • Alexandre Vasseur, Jeffrey Bruffaerts, Ilan Marek. Remote functionalization through alkene isomerization. Nature Chemistry, Nature Publishing Group, 2016, 8 (3), pp.209 - 219. ⟨10.1038/nchem.2445⟩. ⟨hal-01780960⟩
  • Alexandre Vasseur, Caroline Laugel, Dominique Harakat, Jacques Muzart, Jean Le Bras. Ligand-Promoted Reactivity of Alkenes in Dehydrogenative Heck Reactions of Furans and Thiophenes. European Journal of Organic Chemistry, Wiley-VCH Verlag, 2015, 2015 (5), pp.944-948. ⟨10.1002/ejoc.201403475⟩. ⟨hal-02109118⟩
  • Alexandre Vasseur, Jacques Muzart, Jean Le Bras. Ubiquitous Benzoquinones, Multitalented Compounds for Palladium-Catalyzed Oxidative Reactions. European Journal of Organic Chemistry, Wiley-VCH Verlag, 2015, 2015 (19), pp.4053-4069. ⟨10.1002/ejoc.201500080⟩. ⟨hal-02109108⟩
  • Alexandre Vasseur, Lionel Perrin, Odile Eisenstein, Ilan Marek. Remote functionalization of hydrocarbons with reversibility enhanced stereocontrol. Chemical Science , The Royal Society of Chemistry, 2015, 6, pp.2770-2776. ⟨hal-01484410⟩
  • Alexandre Vasseur, Lionel Perrin, Odile Eisenstein, Ilan Marek. Remote functionalization of hydrocarbons with reversibility enhanced stereocontrol. Chemical Science , The Royal Society of Chemistry, 2015, 6, pp.2770-2776. ⟨10.1039/C5SC00445D⟩. ⟨hal-01152129⟩
  • Alexandre Vasseur, Dominique Harakat, Jacques Muzart, Jean Le Bras. Aerobic Dehydrogenative Heck Reactions of Heterocycles with Styrenes: A Negative Effect of Metallic Co-Oxidants. Advanced Synthesis and Catalysis, Wiley-VCH Verlag, 2013, 355 (1), pp.59-67. ⟨10.1002/adsc.201200787⟩. ⟨hal-02109125⟩
  • Alexandre Vasseur, Dominique Harakat, Jacques Muzart, Jean Le Bras. ESI-MS Studies of the Dehydrogenative Heck Reaction of Furans with Acrylates Using Benzoquinone as the Reoxidant and DMSO as the Solvent. Journal of Organic Chemistry, American Chemical Society, 2012, 77 (13), pp.5751-5758. ⟨10.1021/jo300921s⟩. ⟨hal-02109127⟩
  • Alexandre Vasseur, Jacques Muzart, Jean Le Bras. Dehydrogenative Heck Reaction of Furans and Thiophenes with Styrenes under Mild Conditions and Influence of the Oxidizing Agent on the Reaction Rate. Chemistry - A European Journal, Wiley-VCH Verlag, 2011, 17 (45), pp.12556-12560. ⟨10.1002/chem.201101992⟩. ⟨hal-02109134⟩

Book sections2 documents

  • Alexandre Vasseur, Jeffrey Bruffaerts. C(sp3)–H Functionalization by Allylic C–H Activation of Zirconocene Complexes. Science of Synthesis: Knowledge Updates 2016/2, 2016. ⟨hal-01780954⟩
  • Jeffrey Bruffaerts, Alexandre Vasseur. Synthesis and Reactivity of Heteroatom-Substituted Vinylzirconocene Derivatives and Hetarylzirconocenes. Science of Synthesis: Knowledge Updates 2016/2, 2016. ⟨hal-01780956⟩