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Abl interconnects oncogenic Met and p53 core pathways in cancer cells

Flavio Maina , Alessandro Furlan , Filippo Conti , Azeemudeen Hussain , Sylvie Richelme , et al.
Cell Death and Differentiation, 2011, ⟨10.1038/cdd.2011.23⟩
Article dans une revue hal-00628278v1
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Control of cell death/survival balance by the MET dependence receptor

Leslie Duplaquet , Catherine Leroy , Audrey Vinchent , Sonia Paget , Jonathan Lefebvre , et al.
eLife, 2020, 9, pp.e50041. ⟨10.7554/eLife.50041⟩
Article dans une revue hal-03060380v1

‘Click’ synthesis of a triazole-based inhibitor of Met functions in cancer cells

Francesco Colombo , Cristina Tintori , Alessandro Furlan , Stella Borrelli , Michael Christodoulou , et al.
Bioorganic and Medicinal Chemistry Letters, 2012, 22 (14), pp.4693-4696. ⟨10.1016/j.bmcl.2012.05.078⟩
Article dans une revue istex hal-02414569v1

Interdisciplinary approaches to investigate the tumor microenvironment

Alessandro Furlan , Mélanie Arcicasa , Samuel Meignan
Mifobio 2023 Functional Microscopy for Biology, Nov 2023, Hyères, France
Communication dans un congrès hal-04548466v1
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Ets-1 drives breast cancer cell angiogenic potential and interactions between breast cancer and endothelial cells

Alessandro Furlan , Chantal Vercamer , Laurent Héliot , Nicolas Wernert , Xavier Desbiens , et al.
International Journal of Oncology, 2018, 54 (1), pp.29-40. ⟨10.3892/ijo.2018.4605⟩
Article dans une revue hal-02413908v1

Ets-1 controls breast cancer cell balance between invasion and growth

Alessandro Furlan , Chantal Vercamer , Fatima Bouali , Isabelle Damour , Anne Chotteau-Lelievre , et al.
International Journal of Cancer, 2014, 135 (10), pp.2317-2328. ⟨10.1002/ijc.28881⟩
Article dans une revue hal-02414529v1

Hypoxia in Solid Tumors: How Low Oxygenation Impacts the “Six Rs” of Radiotherapy

Andria Rakotomalala , Alexandre Escande , Alessandro Furlan , Samuel Meignan , Eric Lartigau
Frontiers in Endocrinology, 2021, 12, ⟨10.3389/fendo.2021.742215⟩
Article dans une revue hal-04540877v1

How does met regulate the survival/apoptosis balance?

Alessandro Furlan , David Tulasne
Hepatology, 2014, 60 (3), pp.1108-1109. ⟨10.1002/hep.26969⟩
Article dans une revue hal-02414539v1

Ets-1 activation, when tumors crosstalk with their microenvironment.

Alessandro Furlan , Albin Pourtier
Cancer Cell & Microenvironment, 2015, ⟨10.14800/ccm.494⟩
Article dans une revue hal-02413954v1
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Mathematical models converge on PGC1α as the key metabolic integrator of SIRT1 and AMPK regulation of the circadian clock

Alessandro Furlan , Marine Jacquier , Aurore Woller , Laurent Héliot , Hélène Duez , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (27), pp.13171-13172. ⟨10.1073/pnas.1907751116⟩
Article dans une revue inserm-02264503v1
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Combined drug action of 2-phenylimidazo[2,1-b]benzothiazole derivatives on cancer cells according to their oncogenic molecular signatures

Alessandro Furlan , Benjamin Roux , Fabienne Lamballe , Filippo Conti , Nathalie Issaly , et al.
PLoS ONE, 2012, 7 (10), pp.e46738. ⟨10.1371/journal.pone.0046738⟩
Article dans une revue hal-00843384v1
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Combined Drug Action of 2-Phenylimidazo[2,1-b]Benzothiazole Derivatives on Cancer Cells According to Their Oncogenic Molecular Signatures

Alessandro Furlan , Benjamin Roux , Fabienne Lamballe , Filippo Conti , Nathalie Issaly , et al.
PLoS ONE, 2012, 7 (10), pp.e46738. ⟨10.1371/journal.pone.0046738⟩
Article dans une revue hal-02414559v1
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Large-Scale Virtual Screening Against the MET Kinase Domain Identifies a New Putative Inhibitor Type

Emmanuel Bresso , Alessandro Furlan , Philippe Noel , Vincent Leroux , Flavio Maina , et al.
Molecules, 2020, 25 (4), pp.938. ⟨10.3390/molecules25040938⟩
Article dans une revue hal-03049726v1
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HEXIM1 Diffusion in the Nucleus Is Regulated by Its Interactions with Both 7SK and P-TEFb

Alessandro Furlan , Mariano Gonzalez-Pisfil , Aymeric Leray , Dorian Champelovier , Mélanie Henry , et al.
Biophysical Journal, 2019, 117 (9), pp.1615-1625. ⟨10.1016/j.bpj.2019.09.019⟩
Article dans une revue hal-03060372v1

A Bloody Conspiracy— Blood Vessels and Immune Cells in the Tumor Microenvironment

Lisa Terrassoux , Hugo Claux , Salimata Bacari , Samuel Meignan , Alessandro Furlan
Cancers, 2022, 14 (19), pp.4581. ⟨10.3390/cancers14194581⟩
Article dans une revue hal-04540748v1

Met acts through Abl to regulate p53 transcriptional outcomes and cell survival in the developing liver.

Alessandro Furlan , Fabienne Lamballe , Venturina Stagni , Azeemudeen Hussain , Sylvie Richelme , et al.
Journal of Hepatology, 2012, 57 (6), pp.1292-8. ⟨10.1016/j.jhep.2012.07.044⟩
Article dans une revue hal-00843385v1

Le récepteur Met fête ses 30 ans: de la découverte d’un oncogène au développement de thérapies ciblées

Rémi Montagne , Alessandro Furlan , Zoulika Kherrouche , David Tulasne
Médecine/Sciences, 2014, 30 (10), pp.864-873. ⟨10.1051/medsci/20143010013⟩
Article dans une revue hal-02414525v1

Identification of new aminoacid amides containing the imidazo[2,1-b]benzothiazol-2-ylphenyl moiety as inhibitors of tumorigenesis by oncogenic Met signaling

Alessandro Furlan , Francesco Colombo , Andrea Kover , Nathalie Issaly , Cristina Tintori , et al.
European Journal of Medicinal Chemistry, 2012, 47, pp.239-254. ⟨10.1016/j.ejmech.2011.10.051⟩
Article dans une revue istex hal-00763849v1

Ets-1 triggers and orchestrates the malignant phenotype of mammary cancer cells within their matrix environment

Alessandro Furlan , Chantal Vercamer , Xavier Desbiens , Albin Pourtier
Journal of Cellular Physiology, 2008, 215 (3), pp.782-793. ⟨10.1002/jcp.21360⟩
Article dans une revue istex hal-02414579v1

Click' synthesis of a triazole-based inhibitor of Met functions in cancer cells.

Francesco Colombo , Cristina Tintori , Alessandro Furlan , Stella Borrelli , Michael S Christodoulou , et al.
Bioorganic and Medicinal Chemistry Letters, 2012, 22 (14), pp.4693-6. ⟨10.1016/j.bmcl.2012.05.078⟩
Article dans une revue istex hal-00843387v1
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Caspases shutdown nonsense-mediated mRNA decay during apoptosis

Jieshuang Jia , Alessandro Furlan , Sara Gonzalez-Hilarion , Catherine Leroy , Dieter Gruenert , et al.
Cell Death and Differentiation, 2015, 22, pp.1754 - 1763. ⟨10.1038/cdd.2015.18⟩
Article dans une revue hal-03834781v1

ST6GalNAc I expression in MDA-MB-231 breast cancer cells greatly modifies their O-glycosylation pattern and enhances their tumourigenicity.

Sylvain Julien , Eric Adriaenssens , Katherin Ottenberg , Alessandro Furlan , Gilles Courtand , et al.
Glycobiology, 2006, 16, pp.54-64
Article dans une revue hal-00085754v1
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P-TEFb et Brd4

Alessandro Furlan , Florence Agbazahou , Mélanie Henry , Mariano Gonzalez-Pisfil , Corentin Le Nézet , et al.
Médecine/Sciences, 2018, 34 (8-9), pp.685-692. ⟨10.1051/medsci/20183408015⟩
Article dans une revue hal-03060370v1

A tumor-on-chip as a DIPG model mimicking tumor microenvironment

Alessandro Furlan , Lisa Terrassoux , Joanne Balsamelli , Samuel Meignan
Functional investigation of multicellular systems with light probes, Jun 2023, Paris, France
Communication dans un congrès hal-04548485v1

FRET Image Correlation Spectroscopy Reveals RNAPII-Independent P-TEFb Recruitment on Chromatin

Gabriel Bidaux , Corentin Le Nézet , Mariano Gonzalez Pisfil , Mélanie Henry , Alessandro Furlan , et al.
Biophysical Journal, 2018, 114 (3), pp.522-533. ⟨10.1016/j.bpj.2017.11.3783⟩
Article dans une revue hal-02413911v1

Exon 14 Deleted MET Receptor as a New Biomarker and Target in Cancers

Alexis Cortot , Zoulika Kherrouche , Clotilde Descarpentries , Marie Wislez , Simon Baldacci , et al.
JNCI: Journal of the National Cancer Institute, 2017, 109 (5), pp.djw262. ⟨10.1093/jnci/djw262⟩
Article dans une revue hal-02413937v1