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Clinical utility of circulating DNA analysis for rapid detection of actionable mutations to select metastatic colorectal patients for anti-EGFR treatment

A.R. Thierry , S. El Messaoudi , C. Mollevi , J. L. Raoul , R. Guimbaud , et al.
Annals of Oncology, 2017, 28 (9), pp.2149 - 2159. ⟨10.1093/annonc/mdx330⟩
Article dans une revue hal-01682168v1
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Blood contains circulating cell free respiratory competent mitochondria

Zahra Al Amir Dache , Amaëlle Otandault , Rita Tanos , Brice Pastor , Romain Meddeb , et al.
FASEB Journal, 2020, 34 (3), pp.3616-3630. ⟨10.1096/fj.201901917RR⟩
Article dans une revue hal-02504546v1

Recent advances in circulating nucleic acids in oncology

A. Otandault , P. Anker , Z. Al Amir Dache , V. Guillaumon , R. Meddeb , et al.
Annals of Oncology, 2019, 30 (3), pp.374-384. ⟨10.1093/annonc/mdz031⟩
Article dans une revue hal-02462645v1
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Monitoring levels of circulating cell‐free DNA in patients with metastatic colorectal cancer as a potential biomarker of responses to regorafenib treatment

Brice Pastor , André Thierry , Julie Henriques , Isabelle Trouilloud , Christophe Tournigand , et al.
Molecular Oncology, 2021, 15 (9), pp.2401-2411. ⟨10.1002/1878-0261.12972⟩
Article dans une revue hal-03216431v1

Cellular uptake and intracellular fate of antisense oligonucleotides

Alain R Thierry , E. Vives , J. P. Richard , P. Prevot , C. Martinand-Mari , et al.
Current Opinion in Molecular Therapeutics, 2003, 5 (2), pp.133--138. ⟨10.1016/0962-8924(92)90100-2⟩
Article dans une revue istex hal-02239718v1
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Circulating Cell-Free DNA from Colorectal Cancer Patients May Reveal High KRAS or BRAF Mutation Load

Florent Mouliere , Safia El Messaoudi , Celine Gongora , Anne-Sophie Guedj , Bruno Robert , et al.
Translational Oncology, 2013, 6 (3), pp.319 - 328. ⟨10.1593/tlo.12445⟩
Article dans une revue hal-01826199v1

A Step Closer to Cancer Screening by Blood Test

Alain R Thierry
Clinical Chemistry, 2018, 64 (10), pp.1420-1422. ⟨10.1373/clinchem.2018.287847⟩
Article dans une revue hal-02292769v1

Clinical validation of the detection of KRAS and BRAF mutations from circulating tumor DNA

Alain Thierry , Florent Mouliere , Safia El Messaoudi , Caroline Mollevi , Evelyne El Lopez-Crapez , et al.
Nature Medicine, 2014, 20 (4), pp.430-435. ⟨10.1038/nm.3511⟩
Article dans une revue hal-02362372v1
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Modelling of complex biological systems in the context of genomics: an account of a multidisciplinary thematic seminar held in Montpellier (France) in April 2005

Alain Thierry , François Képès , Patrick Amar , Georgia Barlovatz-Meimon , Gilles Bernot , et al.
Journal of Biological Physics and Chemistry, 2006, 6, pp.103-107
Article dans une revue hal-00830064v1
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Circulating nuclear DNA structural features, origins, and complete size profile revealed by fragmentomics

Cynthia Sanchez , Benoit Roch , Thibault Mazard , Philippe Jl Blache , Zahra Al Amir Dache , et al.
JCI Insight, 2021, 6, ⟨10.1172/jci.insight.144561⟩
Article dans une revue hal-03367566v1

Circulating DNA Demonstrates Convergent Evolution and Common Resistance Mechanisms during Treatment of Colorectal Cancer.

Alain R Thierry , Brice Pastor , Jiang Zhi Qin , Katsiampoura D Anastasia , Christine Parseghian
Clinical Cancer Research, 2017, ⟨10.1158/1078-0432.CCR-17-0232⟩
Article dans une revue hal-02292236v1

The Mimic Chain Reaction

Vic Norris , Alain R Thierry , Patrick Amar , Barry I Holland , Franck Molina
Journal of Molecular Microbiology and Biotechnology, 2012, 22 (5), pp.335-343. ⟨10.1159/000345328⟩
Article dans une revue hal-00761608v1

Computing with bacterial constituents, cells and populations: from bioputing to bactoputing

Vic Norris , Abdallah Zemirline , Patrick Amar , Jean Nicolas Audinot , Pascal Ballet , et al.
Theorie in den Biowissenschaften / Theory in Biosciences, 2011, 130 (3), pp.211-228. ⟨10.1007/s12064-010-0118-4⟩
Article dans une revue hal-00643738v1
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High Fragmentation Characterizes Tumour-Derived Circulating DNA

Florent Mouliere , Bruno Robert , Erika Arnau Peyrotte , Maguy del Rio , Marc Ychou , et al.
PLoS ONE, 2011, 6 (9), pp.e23418. ⟨10.1371/journal.pone.0023418⟩
Article dans une revue hal-02362667v1
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Neutrophil Extracellular Traps and By-Products Play a Key Role in COVID-19: Pathogenesis, Risk Factors, and Therapy

Alain R Thierry , Benoit Roch
Journal of Clinical Medicine, 2020, 9 (9), pp.2942. ⟨10.3390/jcm9092942⟩
Article dans une revue hal-03339360v1
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Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care

Safia El Messaoudi , Florent Mouliere , Stanislas Du Manoir , Caroline Bascoul-Mollevi , Brigitte Gillet , et al.
Clinical Cancer Research, 2016, 22 (12), pp.3067 - 3077. ⟨10.1158/1078-0432.CCR-15-0297⟩
Article dans une revue hal-01826197v1
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Machine Learning‐Assisted Evaluation of Circulating DNA Quantitative Analysis for Cancer Screening

Rita Tanos , Guillaume Tosato , Amaelle Otandault , Zahra Al Amir Dache , Laurence Pique Lasorsa , et al.
Advanced Science, 2020, 7 (18), pp.2000486. ⟨10.1002/advs.202000486⟩
Article dans une revue hal-03337999v1
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From bioputing to bactoputing: computing with bacteria

Victor Norris , Abdallah Zemirline , Patrick Amar , Pascal Ballet , Eshel Ben Jacob , et al.
Lille Spring School on Modelling Complex Biological Systems in the Context of Genomics, Apr 2008, Paris, France. pp.123-150
Communication dans un congrès hal-00340470v1
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Multi-marker analysis of circulating cell-free DNA toward personalized medicine for colorectal cancer.

Florent Mouliere , Safia El Messaoudi , Dalong Pang , Anatoly Dritschilo , Alain R Thierry
Molecular Oncology, 2014, 8 (5), pp.927-41. ⟨10.1016/j.molonc.2014.02.005⟩
Article dans une revue inserm-01076572v1

New insights into structural features and optimal detection of circulating tumor DNA determined by single-strand DNA analysis

Cynthia Sanchez , Matthew Snyder , Rita Tanos , Jay Shendure , Alain R Thierry
npj Genomic Medicine, 2018, 3, pp.31. ⟨10.1038/s41525-018-0069-0⟩
Article dans une revue hal-02292243v1
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Neutrophil extracellular traps have auto-catabolic activity and produce mononucleosome-associated circulating DNA

Ekaterina Pisareva , Lucia Mihalovičová , Brice Pastor , Andrei Kudriavtsev , Alexia Mirandola , et al.
Genome Medicine, 2022, 14 (1), pp.135. ⟨10.1186/s13073-022-01125-8⟩
Article dans une revue hal-03877035v1
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Quantifying circulating cell-free DNA in humans

Romain Meddeb , Zahra Al Amir Dache , Simon Thezenas , Amaëlle Otandault , Rita Tanos , et al.
Scientific Reports, 2019, 9 (1), pp.5220. ⟨10.1038/s41598-019-41593-4⟩
Article dans une revue hal-02327317v1
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Mechanical signatures of human colon cancers

Evelyne Lopez-Crapez , Luca Costa , Guillaume Tosato , Jeanne Ramos , Thibault Mazard , et al.
Scientific Reports, 2022, 12 (1), pp.12475. ⟨10.1038/s41598-022-16669-3⟩
Article dans une revue hal-03811868v1

Lipoplex and peptide-based strategies for the delivery of steric-block oligonucleotides.

Sarah Resina , Saïd Abes , John J Turner , Paul Prevot , Adrian Travo , et al.
International Journal of Pharmaceutics, 2007, epub ahead of print. ⟨10.1016/j.ijpharm.2007.04.039⟩
Article dans une revue istex hal-00167451v1
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[Liquid biopsy: a possible approach for cancer screening].

Alain R Thierry , Rita Tanos
Médecine/Sciences, 2018, 34 (10), pp.824-832. ⟨10.1051/medsci/2018208⟩
Article dans une revue hal-02292799v1

Guidelines for the Preanalytical Conditions for Analyzing Circulating Cell-Free DNA

Romain Meddeb , Ekaterina Pisareva , Alain Thierry
Clinical Chemistry, 2019, 65 (5), pp.623-633. ⟨10.1373/clinchem.2018.298323⟩
Article dans une revue hal-02421322v1
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Hypoxia differently modulates the release of mitochondrial and nuclear DNA

Amaëlle Otandault , Jean-Daniel Abraham , Zahra Al Amir Dache , Abdelnaby Khalyfa , Isabelle Jariel-Encontre , et al.
British Journal of Cancer, 2020, 122, pp.715 - 725. ⟨10.1038/s41416-019-0716-y⟩
Article dans une revue hal-02504555v2
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Origins, structures, and functions of circulating DNA in oncology

Alain R Thierry , S. El Messaoudi , P. Gahan , P. Anker , M. Stroun
Cancer and Metastasis Reviews, 2016, 35 (3), pp.347-376. ⟨10.1007/s10555-016-9629-x⟩
Article dans une revue hal-02299112v1
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Origin and quantification of circulating DNA in mice with human colorectal cancer xenografts

Alain Thierry , Florent Mouliere , Celine Gongora , Jérémy Ollier , Bruno Robert , et al.
Nucleic Acids Research, 2010, 38 (18), pp.6159-6175. ⟨10.1093/nar/gkq421⟩
Article dans une revue hal-02362686v1

Dual Inhibition of EGFR and c-Src by Cetuximab and Dasatinib Combined with FOLFOX Chemotherapy in Patients with Metastatic Colorectal Cancer

Christine Parseghian , Nila Parikh , Ji Yuan Wu , Zhi-Qin Jiang , Laura Henderson , et al.
Clinical Cancer Research, 2017, 23 (15), pp.4146-4154. ⟨10.1158/1078-0432.CCR-16-3138⟩
Article dans une revue hal-02301894v1