Alain Legrand

Documents

Publications

	Disturbed expression of autophagy genes in blood of Parkinson’s disease patients Saïd El Haddad , Amandine Serrano , Fréderic Moal , Thierry Normand , Chloé Robin Gene, 2020, 738, pp.144454. ⟨10.1016/j.gene.2020.144454⟩ Article dans une revue hal-02501027v1
	Reply B. Chauveau , C. Auclair , A. Legrand , R. Mangione , Laurent Gerbaud Ultrasound in Obstetrics and Gynecology = Ultrasound in Obstetrics & Gynecology, 2019, 53 (2), pp.276-277. ⟨10.1002/uog.20164⟩ Article dans une revue hal-03049060v1
	Interaction of Alpha-synuclein with Cytogaligin, a protein encoded by the proapoptotic gene GALIG Saïd El Haddad , Amandine Serrano , Thierry Normand , Chloé Robin , Martine Dubois Biochemical and Biophysical Research Communications, 2018, 495 (1), pp.787-792. ⟨10.1016/j.bbrc.2017.11.078⟩ Article dans une revue hal-01966108v1
	Recombinant yeast and human cells as screening tools to search for antibacterial agents targeting the transcription termination factor Rho Kévin Moreau , Justine Surand , Aurélia Le Dantec , Christine Mosrin-Huaman , Alain Legrand Journal of Antibiotics, 2018, 71 (4), pp.447-455 Article dans une revue hal-01966171v1
	Dysregulation of apoptosis and autophagy gene expression in peripheral blood mononuclear cells of efficiently treated HIV-infected patients Amandine Serrano , Saïd El Haddad , Fréderic Moal , Thierry Prazuck , Eric Legac AIDS. Official journal of the international AIDS Society, 2018, 32 (12), pp.1579 - 1587. ⟨10.1097/QAD.0000000000001851⟩ Article dans une revue hal-01936094v1
	The addressing fragment of mitogaligin: first insights into functional and structural properties. Violette Senille , Dominique Lelievre , Françoise Paquet , Norbert Garnier , Ned Lamb ChemBioChem, 2013, 14 (6), pp.711-20. ⟨10.1002/cbic.201200715⟩ Article dans une revue hal-00817503v1
	Opposing Mcl-1, the GALIG proapoptotic gene is upregulated as neutrophils die and underexpressed in Acute Myeloid Leukemia cells. Lucile Mollet , Pauline Robinet , Martine Dubois , Axel Aurouet , Thierry Normand Molecular Immunology, 2013, 56 (1-2), pp.123-8. ⟨10.1016/j.molimm.2013.04.012⟩ Article dans une revue hal-00840170v1
	The mitogaligin protein is addressed to the nucleus via a non-classical localization signal Pauline Robinet , Lucile Mollet , Patrick Gonzalez , Thierry Normand , Stephane Charpentier Biochemical and Biophysical Research Communications, 2010, 392 (1), pp.53-57. ⟨10.1016/j.bbrc.2009.12.162⟩ Article dans une revue hal-00529397v1
	Multiple reprobing of Western blots after inactivation of peroxidase activity by its substrate, hydrogen peroxide Alexis D. Sennepin , Stéphane Charpentier , Thierry Normand , Cedric Sarre , Alain Legrand Analytical Biochemistry, 2009, 393 (1), pp.129-131. ⟨10.1016/j.ab.2009.06.004⟩ Article dans une revue hal-00525339v1
	Apoptotic activity of a nuclear form of mitogaligin, a cell death protein Patrick Gonzalez , Pauline Robinet , Stéphane Charpentier , Lucile Mollet , Thierry Normand Biochemical and Biophysical Research Communications, 2009, 378 (4), pp.816-820. ⟨10.1016/j.bbrc.2008.11.133⟩ Article dans une revue hal-00522444v1
	Glycofection: The Ubiquitous Roles of Sugar Bound on Glycoplexes Valerie Boutin , Alain Legrand , Roger Mayer , Maurice Nachtigal , Michel Monsigny Drug Delivery, 2008, 6 (1), pp.45-50. ⟨10.1080/107175499267156⟩ Article dans une revue hal-02138035v1
	Destabilization of Membranes Containing Cardiolipin or Its Precursors by Peptides Derived from Mitogaligin, a Cell Death Protein Patrick Gonzalez , Mélanie Duneau , Stéphane Charpentier , Thierry Normand , Lucile Mollet Biochemistry, 2007, 46 (25), pp.7374-7382. ⟨10.1021/bi700213p⟩ Article dans une revue hal-00159568v1
	Protective Effects of 4-Hydroxycinnamic Ethyl Ester Derivatives and Related Dehydrodimers against Oxidation of LDL: Radical Scavengers or Metal Chelators? Anne Neudörffer , Jean-Pierre Desvergne , Dominique Bonnefont-Rousselot , Alain Legrand , Maurice-Bernard Fleury Journal of Agricultural and Food Chemistry, 2006, 54 (5), pp.1898-1905. ⟨10.1021/jf052923p⟩ Article dans une revue hal-02384987v1
	Galig, a novel cell death gene that encodes a mitochondrial protein promoting cytochrome c release M. Duneau , M. Boyer Guittaut , P. Gonzalez , S. Charpentier , T. Normand Experimental Cell Research, 2005, 302, pp.194-205 Article dans une revue hal-00088588v1
	Identification of an Internal Gene to the Human Galectin-3 Gene with Two Different Overlapping Reading Frames That Do Not Encode Galectin-3 Michaël Guittaut , Stéphane Charpentier , Thierry Normand , Martine Dubois , Jacques Raimond Journal of Biological Chemistry, 2001, 276 (4), pp.2652-2657. ⟨10.1074/jbc.m002523200⟩ Article dans une revue hal-02137994v1
	The Tat protein of HIV-1 induces galectin-3 expression S. Fogel , M. Guittaut , Alain Legrand , M. Monsigny , E. Hebert Glycobiology, 1999, 9 (4), pp.383-387. ⟨10.1093/glycob/9.4.383⟩ Article dans une revue hal-02138044v1
	The sugar binding activity of MR60, a mannose-specific shuttling lectin, requires a dimeric state V. Carrière , V. Piller , Alain Legrand , M. Monsigny , A.C. Roche Glycobiology, 1999, 9 (10), pp.995-1002. ⟨10.1093/glycob/9.10.995⟩ Article dans une revue hal-02138032v1
	A Chromosome 4 Satellite I DNA Isolated from SV40-Transformed Human Cells Alain Legrand , Drazen B. Jimonjic , Nicolae C. Popescu , Maurice Nachtigal DNA Research, 1998, 5 (5), pp.271-276. ⟨10.1093/dnares/5.5.271⟩ Article dans une revue hal-02138074v1
	Galectin-3 gene (LGALS3) expression in experimental atherosclerosis and cultured smooth muscle cells. C Arar , J.C Gaudin , L Capron , Alain Legrand FEBS Letters, 1998, 430 (3), pp.307-311. ⟨10.1016/S0014-5793(98)00683-8⟩ Article dans une revue hal-02138144v1
	Mapping of the galectin-3 gene (LGALS3) to human chromosome 14 at region 14q21-22. J. Raimond , D Zimonjic , C. Mignon , M. Mattei , N Popescu Mammalian Genome, 1997, 8 (9), pp.706-707 Article dans une revue hal-02138375v1
	Transformation of rabbit vascular smooth muscle cells by human cytomegalovirus morphological transforming region I. Alain Legrand , E.P Mayer , S Dalvi , M Nachtigal American Journal of Pathology, 1997, 151 (5), pp.1387-95 Article dans une revue hal-02138369v1
	Modulation of the expression of the rabbit galectin-3 gene by p53 and c-Ha-ras proteins and PMA Jean-Charles Gaudin , Chantal Arar , Michel Monsigny , Alain Legrand Glycobiology, 1997, 7 (8), pp.1089-1098. ⟨10.1093/glycob/7.8.1089⟩ Article dans une revue hal-02138352v1
	Isolation of carbohydrate metabolic clones from cultured astrocytes V Vergé , Alain Legrand , T Hévor Glia, 1996, 18 (3), pp.244-254. ⟨10.1002/(SICI)1098-1136(199611)18:3<244::AID-GLIA8>3.0.CO;2-Z⟩ Article dans une revue hal-02138380v1
	Mapping of the MR60/ERGIC-53 gene to human chromosome 18q21.3-18q22 by in situ hybridization. C Arar , C. Mignon , M. Mattei , M. Monsigny , Alexis Roche Mammalian Genome, 1996, 7 (10), pp.791-2. ⟨10.1007/s003359900238⟩ Article dans une revue hal-02138384v1
	ERGIC-53, a Membrane Protein of the Endoplasmic Reticulum-Golgi Intermediate Compartment, Is Identical to MR60, an Intracellular Mannose-specific Lectin of Myelomonocytic Cells Chantal Arar , Valérie Carpentier , Jean-Pierre Le Caer , Michel Monsigny , Alain Legrand Journal of Biological Chemistry, 1995, 270 (8), pp.3551-3553. ⟨10.1074/jbc.270.8.3551⟩ Article dans une revue hal-02138409v1
	Transcriptional expression of mannose receptor gene during differentiation of human macrophages. F Rouleux-Bonnin , M. Monsigny , Alain Legrand Biochemical and Biophysical Research Communications, 1995, 217 (1), pp.106-12 Article dans une revue hal-02138393v1
	The second intron of the human galectin-3 gene has a strong promoter activity down-regulated by p53. J Raimond , F Rouleux , M. Monsigny , Alain Legrand FEBS Letters, 1995, 363 (1-2), pp.165-9. ⟨10.1016/0014-5793(95)00310-6⟩ Article dans une revue hal-02138402v1
	Cloning of the cDNA encoding rabbit galectin-3. J-C Gaudin , M. Monsigny , Alain Legrand Gene, 1995, 163 (2), pp.249-52. ⟨10.1016/0378-1119(95)00388-M⟩ Article dans une revue hal-02138396v1
	An EBV-Based Vector Allowing a High Level of LTRHIV-Directed Expression in Human Cells J. Raimond , C. Plessis , F. Fargette , Alain Legrand , E. Hebert Plasmid, 1994, 32 (1), pp.70-74. ⟨10.1006/plas.1994.1045⟩ Article dans une revue hal-02138444v1
	A Negative Regulatory Element of the Macrophage-Specific Human Mannose Receptor Gene Represses Its Expression in Nonmyeloid Cells Florence Rouleux , Michel Monsigny , Alain Legrand Experimental Cell Research, 1994, 214 (1), pp.113-119. ⟨10.1006/excr.1994.1239⟩ Article dans une revue hal-02138011v1
	Specific gene transfer mediated by lactosylated poly-L-lysine into hepatoma cells Patrick Midoux , Christina Mendes , Alain Legrand , Jacques Raimond , Roger Mayer Nucleic Acids Research, 1993, 21 (4), pp.871-878. ⟨10.1093/nar/21.4.871⟩ Article dans une revue hal-02138456v1
	A SV-40 immortalized murine endothelial cell line from peripheral lymph node high endothelium expresses a new alpha-L-fucose binding protein. N Bizouarne , V. Denis , Alain Legrand , M. Monsigny , C. Kieda Biology of the Cell, 1993, 79 (3), pp.209-18. ⟨10.1016/0248-4900(93)90139-6⟩ Article dans une revue hal-02138452v1
	Homologous Recombination of a Plasmid Containing the SV40 Early Region in Rabbit Cells Alain Legrand , Maurice Nachtigal Intervirology, 1991, 32 (3), pp.173-184. ⟨10.1159/000150197⟩ Article dans une revue hal-02138462v1
	Characterization of human vascular smooth muscle cells transformed by the early genetic region of SV40 virus. Alain Legrand , P Greenspan , M Nagpal , S Nachtigal , M Nachtigal American Journal of Pathology, 1991, 139 (3), pp.629-640 Article dans une revue hal-02138458v1
	Transformation of rabbit vascular smooth muscle cells by transfection with the early region of SV40 DNA. M Nachtigal , Alain Legrand , M Nagpal , S Nachtigal , P Greenspan American Journal of Pathology, 1990, 136 (2), pp.297-306 Article dans une revue hal-02138474v1
	Immortalization of Rabbit Vascular Smooth Muscle Cells after Transfection with a Fragment of the BglII N Region of Herpes Simplex Virus Type 2 DNA M. Nachtigal , Alain Legrand , P. Greenspan , S Nachtigal , M. Nagpal Intervirology, 1990, 31 (2-4), pp.166-174. ⟨10.1159/000150151⟩ Article dans une revue hal-02138469v1
	Characterization of a continuous smooth muscle cell line derived from rabbit aorta. M Nachtigal , M Nagpal , P Greenspan , A Nachtigal , Alain Legrand In vitro cellular & developmental biology : journal of the Tissue Culture Association, 1989, 25 (10), pp.892-8. ⟨10.1007/BF02624001⟩ Article dans une revue hal-02138476v1
	Liposomes as carriers for in vivo gene transfer and expression. C. Nicolau , Alain Legrand , E. Grosse Methods in Enzymology, 1987, 149, pp.157-76. ⟨10.1016/0076-6879(87)49054-X⟩ Article dans une revue hal-02138481v1
	Biologically active, recombinant DNA in clathrin-coated vesicles isolated from rat livers after in vivo injection of liposome-encapsulated DNA. P Nandi , Alain Legrand , C. Nicolau Journal of Biological Chemistry, 1986, 261 (35), pp.16722-6 Article dans une revue hal-02138484v1
	Targeted and nontargeted liposomes for in vivo transfer to rat liver cells of a plasmid containing the preproinsulin I gene. P. Soriano , J Dijkstra , Alain Legrand , H. Spanjer , D. Londos-Gagliardi Proceedings of the National Academy of Sciences of the United States of America, 1983, 80 (23), pp.7128-7131. ⟨10.1073/pnas.80.23.7128⟩ Article dans une revue hal-02138490v1

	Cytogaligin, an additional link between Parkinson’s disease and autophagy pathways? S. El Haddad , A. Serrano , Thierry Normand , Fabienne Brulé-Morabito , L. Mollet 7e Congrès du CFATG, Nov 2017, Paris, France Communication dans un congrès hal-02934905v1
	Etude de l’expression génique dans la maladie de Parkinson S El Haddad , C Ozsancak , A Serrano , M Dubois , P. Auzou Journées de Neurologie de Langue Française, Apr 2016, Nantes, France Communication dans un congrès hal-03661927v1
	During efficient Anti-RetroViral (ARV) therapy, the expression of GALIG and its interacting partners involved in macroautophagy are deregulated A. Serrano , Thierry Normand , S. El Haddad , M. Dubois , Stéphane Charpentier 6es Journées Scientifiques du CFATG, Oct 2016, Bordeaux, France Communication dans un congrès hal-02934903v1
	Genes de l’autophagie : marqueurs sanguins potentiels de la maladie de Parkinson S El Haddad , A Serrano , C Ozsancak , P. Auzou , F Moal Journées de Neurologie de Langue Française, Apr 2016, Nantes, France Communication dans un congrès hal-03661930v1
	GALIG, gène inducteur de la mort cellulaire, s’exprime au cours de la différenciation myéloïde A Serrano , T Guery , S El Haddad , M Dubois , M Schoenwald 10es Journées du Cancéropole Grand Ouest, Jun 2016, Les Sables d'Olonne, France Communication dans un congrès hal-03661932v1
	Cytogaligin, one of the proteins produced by the proapoptotic GALIG gene, interacts with autophagy and proteasome molecules A Serrano , S El Haddad , T Normand , M Dubois , T Guery 7th Proteasome Autophagy Workshop, Apr 2016, Clermont-Ferrand, France Communication dans un congrès hal-03661923v1

Alain Legrand

Publications

Disturbed expression of autophagy genes in blood of Parkinson’s disease patients

Reply

Interaction of Alpha-synuclein with Cytogaligin, a protein encoded by the proapoptotic gene GALIG

Recombinant yeast and human cells as screening tools to search for antibacterial agents targeting the transcription termination factor Rho

Dysregulation of apoptosis and autophagy gene expression in peripheral blood mononuclear cells of efficiently treated HIV-infected patients

The addressing fragment of mitogaligin: first insights into functional and structural properties.

Opposing Mcl-1, the GALIG proapoptotic gene is upregulated as neutrophils die and underexpressed in Acute Myeloid Leukemia cells.

The mitogaligin protein is addressed to the nucleus via a non-classical localization signal

Multiple reprobing of Western blots after inactivation of peroxidase activity by its substrate, hydrogen peroxide

Apoptotic activity of a nuclear form of mitogaligin, a cell death protein

Glycofection: The Ubiquitous Roles of Sugar Bound on Glycoplexes

Destabilization of Membranes Containing Cardiolipin or Its Precursors by Peptides Derived from Mitogaligin, a Cell Death Protein

Protective Effects of 4-Hydroxycinnamic Ethyl Ester Derivatives and Related Dehydrodimers against Oxidation of LDL: Radical Scavengers or Metal Chelators?

Galig, a novel cell death gene that encodes a mitochondrial protein promoting cytochrome c release

Identification of an Internal Gene to the Human Galectin-3 Gene with Two Different Overlapping Reading Frames That Do Not Encode Galectin-3

The Tat protein of HIV-1 induces galectin-3 expression

The sugar binding activity of MR60, a mannose-specific shuttling lectin, requires a dimeric state

A Chromosome 4 Satellite I DNA Isolated from SV40-Transformed Human Cells

Galectin-3 gene (LGALS3) expression in experimental atherosclerosis and cultured smooth muscle cells.

Mapping of the galectin-3 gene (LGALS3) to human chromosome 14 at region 14q21-22.

Transformation of rabbit vascular smooth muscle cells by human cytomegalovirus morphological transforming region I.

Modulation of the expression of the rabbit galectin-3 gene by p53 and c-Ha-ras proteins and PMA

Isolation of carbohydrate metabolic clones from cultured astrocytes

Mapping of the MR60/ERGIC-53 gene to human chromosome 18q21.3-18q22 by in situ hybridization.

ERGIC-53, a Membrane Protein of the Endoplasmic Reticulum-Golgi Intermediate Compartment, Is Identical to MR60, an Intracellular Mannose-specific Lectin of Myelomonocytic Cells

Transcriptional expression of mannose receptor gene during differentiation of human macrophages.

The second intron of the human galectin-3 gene has a strong promoter activity down-regulated by p53.

Cloning of the cDNA encoding rabbit galectin-3.

An EBV-Based Vector Allowing a High Level of LTRHIV-Directed Expression in Human Cells

A Negative Regulatory Element of the Macrophage-Specific Human Mannose Receptor Gene Represses Its Expression in Nonmyeloid Cells

Specific gene transfer mediated by lactosylated poly-L-lysine into hepatoma cells

A SV-40 immortalized murine endothelial cell line from peripheral lymph node high endothelium expresses a new alpha-L-fucose binding protein.

Homologous Recombination of a Plasmid Containing the SV40 Early Region in Rabbit Cells

Characterization of human vascular smooth muscle cells transformed by the early genetic region of SV40 virus.

Transformation of rabbit vascular smooth muscle cells by transfection with the early region of SV40 DNA.

Immortalization of Rabbit Vascular Smooth Muscle Cells after Transfection with a Fragment of the BglII N Region of Herpes Simplex Virus Type 2 DNA

Characterization of a continuous smooth muscle cell line derived from rabbit aorta.

Liposomes as carriers for in vivo gene transfer and expression.

Biologically active, recombinant DNA in clathrin-coated vesicles isolated from rat livers after in vivo injection of liposome-encapsulated DNA.

Targeted and nontargeted liposomes for in vivo transfer to rat liver cells of a plasmid containing the preproinsulin I gene.

Cytogaligin, an additional link between Parkinson’s disease and autophagy pathways?

Etude de l’expression génique dans la maladie de Parkinson

During efficient Anti-RetroViral (ARV) therapy, the expression of GALIG and its interacting partners involved in macroautophagy are deregulated

Genes de l’autophagie : marqueurs sanguins potentiels de la maladie de Parkinson

GALIG, gène inducteur de la mort cellulaire, s’exprime au cours de la différenciation myéloïde

Cytogaligin, one of the proteins produced by the proapoptotic GALIG gene, interacts with autophagy and proteasome molecules