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Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S

Matthieu Galibert , Mylène Wartenberg , Fabien Lecaille , Ahlame Saidi , Sylvie Mavel , et al.
European Journal of Medicinal Chemistry, 2018, 144, pp.201-210. ⟨10.1016/j.ejmech.2017.12.012⟩
Article dans une revue hal-03677245v1

Regulation of the Proteolytic Activity of Cysteine Cathepsins by Oxidants

Gilles Lalmanach , Ahlame Saidi , Paul Bigot , Thibault Chazeirat , Fabien Lecaille , et al.
International Journal of Molecular Sciences, 2020, 21 (6), pp.1944. ⟨10.3390/ijms21061944⟩
Article dans une revue hal-03677271v1
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Rat cathepsin K: Enzymatic specificity and regulation of its collagenolytic activity

Fabien Lecaille , Thibault Chazeirat , Krzysztof Bojarski , Justine Renault , Ahlame Saidi , et al.
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2020, 1868 (2), pp.140318 -. ⟨10.1016/j.bbapap.2019.140318⟩
Article dans une revue hal-03677265v1

Modulation of the expression and activity of cathepsin S in reconstructed human skin by neohesperidin dihydrochalcone

J. Sage , J. Renault , R. Domain , K.K. Bojarski , T. Chazeirat , et al.
Matrix Biology, 2022, 107, pp.97-112. ⟨10.1016/j.matbio.2022.02.003⟩
Article dans une revue hal-03677291v1

Cigarette smoke induces overexpression of active human cathepsin S in lungs from current smokers with or without COPD

Pierre-Marie Andrault , Andrea Schamberger , Thibault Chazeirat , Damien Sizaret , Justine Renault , et al.
American Journal of Physiology - Lung Cellular and Molecular Physiology, 2019, 317 (5), pp.L625-L638. ⟨10.1152/ajplung.00061.2019⟩
Article dans une revue hal-02974308v1
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The abnormal accumulation of heparan sulfate in patients with mucopolysaccharidosis prevents the elastolytic activity of cathepsin V

Thibault Chazeirat , Sophie Denamur , Krzysztof Bojarski , Pierre-Marie Andrault , Damien Sizaret , et al.
Carbohydrate Polymers, 2021, 253, pp.117261 -. ⟨10.1016/j.carbpol.2020.117261⟩
Article dans une revue hal-03677275v1

Cathepsin V: Molecular characteristics and significance in health and disease

Fabien Lecaille , Thibault Chazeirat , Ahlame Saidi , Gilles Lalmanach
Molecular Aspects of Medicine, 2022, pp.101086. ⟨10.1016/j.mam.2022.101086⟩
Article dans une revue hal-03677295v1

Upregulation of gut cathepsin L during Eimeria tenella infection

Ahlame Saidi , Pauline Gaboriaud , Anne-Christine Lalmanach , Lise Vanderlynden , Aurélie Fessard , et al.
Research in Veterinary Science, 2021, 140, pp.109-116. ⟨10.1016/j.rvsc.2021.08.013⟩
Article dans une revue hal-03331820v1

Imaging of extracellular cathepsin S activity by a selective near infrared fluorescence substrate-based probe

Mylène Wartenberg , Ahlame Saidi , Mathieu Galibert , Alix Joulin-Giet , Julien Burlaud-Gaillard , et al.
Biochimie, 2019, 166, pp.84-93. ⟨10.1016/j.biochi.2019.03.013⟩
Article dans une revue hal-03677252v1

Cigarette smoke induces overexpression of active human cathepsin S in lungs from current smokers with or without COPD

Pierre-Marie Andrault , Andrea Schamberger , Thibault Chazeirat , Damien Sizaret , Justine Renault , et al.
American Journal of Physiology - Lung Cellular and Molecular Physiology, 2019, 317 (5), pp.L625-L638. ⟨10.1152/ajplung.00061.2019⟩
Article dans une revue hal-03534488v1

Cigarette smoke induces overexpression of active human cathepsin S in lungs from current smokers with or without COPD

Pierre-Marie Andrault , Andrea Schamberger , Thibault Chazeirat , Damien Sizaret , Justine Renault , et al.
American Journal of Physiology - Lung Cellular and Molecular Physiology, 2019, 317 (5), pp.L625-L638. ⟨10.1152/ajplung.00061.2019⟩
Article dans une revue hal-03677257v1

Regulation of the Proteolytic Activity of Cysteine Cathepsins by Oxidants

Gilles Lalmanach , Ahlame Saidi , Paul Bigot , Thibault Chazeirat , Fabien Lecaille , et al.
International Journal of Molecular Sciences, 2020, 21 (6), pp.1944. ⟨10.3390/ijms21061944⟩
Article dans une revue hal-02977886v1
Image document

Imaging of extracellular cathepsin S activity by a selective near infrared fluorescence substrate-based probe

Mylène Wartenberg , Ahlame Saidi , Mathieu Galibert , Alix Joulin-Giet , Julien Burlaud-Gaillard , et al.
Biochimie, 2019, 166, pp.84-93. ⟨10.1016/j.biochi.2019.03.013⟩
Article dans une revue hal-02088627v1
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Monitoring Human Neutrophil Activation by a Proteinase 3 Near-Infrared Fluorescence Substrate-Based Probe

Ahlame Saidi , Mylène Wartenberg , J.B Madinier , Guy Ilango , Seda Seren , et al.
Bioconjugate Chemistry, 2021, 32 (8), pp.1782-1790. ⟨10.1021/acs.bioconjchem.1c00267⟩
Article dans une revue hal-03525228v1

Cigarette smoke induces overexpression of active human cathepsin S in lungs from current smokers with or without COPD

Pierre-Marie Andrault , Andrea Schamberger , Thibault Chazeirat , Damien Sizaret , Justine Renault , et al.
American Journal of Physiology - Lung Cellular and Molecular Physiology, 2019, 317 (5), pp.L625-L638. ⟨10.1152/ajplung.00061.2019⟩
Article dans une revue hal-03604585v1

Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S

Matthieu Galibert , Mylène Wartenberg , Fabien Lecaille , Ahlame Saidi , Sylvie Mavel , et al.
European Journal of Medicinal Chemistry, 2018, 144, pp.201 - 210. ⟨10.1016/j.ejmech.2017.12.012⟩
Article dans une revue hal-01702303v1

Oxidation of cathepsin S by major chemicals of cigarette smoke

Mylène Wartenberg , Pierre-Marie Andrault , Ahlame Saidi , Paul Bigot , Lydie Nadal-Desbarats , et al.
Free Radical Biology and Medicine, 2020, 150, pp.53 - 65. ⟨10.1016/j.freeradbiomed.2020.02.013⟩
Article dans une revue hal-03489853v1
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Binding of heparan sulfate to human cystatin C modulates inhibition of cathepsin L: Putative consequences in mucopolysaccharidosis

Sophie Denamur , Thibault Chazeirat , Martyna Maszota-Zieleniak , Romain Vivès , Ahlame Saidi , et al.
Carbohydrate Polymers, 2022, 293, pp.119734. ⟨10.1016/j.carbpol.2022.119734⟩
Article dans une revue hal-03706052v1

Cystatin M/E (Cystatin 6): A Janus-Faced Cysteine Protease Inhibitor with Both Tumor-Suppressing and Tumor-Promoting Functions

Mariana Kasabova-Arjomand , Fabien Lecaille , Ahlame Saidi , Gilles Lalmanach
Cancers, 2021, 13 (8), pp.1877. ⟨10.3390/cancers13081877⟩
Article dans une revue hal-03677277v1

Rat cathepsin K: Enzymatic specificity and regulation of its collagenolytic activity

Fabien Lecaille , Thibault Chazeirat , Krzysztof K. Bojarski , Justine Renault , Ahlame Saidi , et al.
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2020, 1868, pp.140318 -. ⟨10.1016/j.bbapap.2019.140318⟩
Article dans une revue hal-03489092v1
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Curcumin inhibits the TGF-β1-dependent differentiation of lung fibroblasts via PPARγ-driven upregulation of cathepsins B and L

Ahlame Saidi , Mariana Kasabova , Lise Vanderlynden , Mylène Wartenberg , Ghania Hounana Kara-Ali , et al.
Scientific Reports, 2019, 9, 15 p. ⟨10.1038/s41598-018-36858-3⟩
Article dans une revue hal-02628303v1
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Oxidation of cathepsin S by major chemicals of cigarette smoke

Mylène Wartenberg , Pierre-Marie Andrault , Ahlame Saidi , Paul Bigot , Lydie Nadal-Desbarats , et al.
Free Radical Biology and Medicine, 2020, 150, pp.53 - 65. ⟨10.1016/j.freeradbiomed.2020.02.013⟩
Article dans une revue hal-03677268v1

Design of both pseudopeptide inhibitors and imaging probes derived from a unique substrate sequence: a versatile molecular toolbox for studying proteases

G. Lalmanach , M. Wartenberg , M. Galibert , A. Saidi , F. Lecaille , et al.
21e réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France
Communication dans un congrès hal-02892793v1

The abnormal accumulation of heparan sulfate in patients with mucopolysaccharidosis prevents the elastolytic activity of cathepsin V

Thibault Chazeirat , Sophie Denamur , Krzysztof K. Bojarski , Pierre-Marie Andrault , Damien Sizaret , et al.
Carbohydrate Polymers, 2021, 253, pp.117261 -. ⟨10.1016/j.carbpol.2020.117261⟩
Article dans une revue hal-03493189v1