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Aberrant repair initiated by mismatch-specific thymine-DNA glycosylases provides a mechanism for the mutational bias observed in CpG islands

 Ibtissam Talhaoui , Sophie Couvé , Laurent Gros , Alexander Ishchenko , Bakhyt Matkarimov , et al.
Nucleic Acids Research, 2014, 42 (10), pp.6300-6313. ⟨10.1093/nar/gku246⟩
Article dans une revue hal-02393707v1
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Insight into DNA substrate specificity of PARP1-catalysed DNA poly(ADP-ribosyl)ation

 Elie Matta , Assel Kiribayeva , Bekbolat Khassenov , Bakhyt T Matkarimov , Alexander A Ishchenko
Scientific Reports, 2020, 10 (1), ⟨10.1038/s41598-020-60631-0⟩
Article dans une revue hal-03033192v1

Step-by-step mechanism of DNA damage recognition by human 8-oxoguanine DNA glycosylase

 Alexandra Kuznetsova , Nikita Kuznetsov , Alexander Ishchenko , Murat Saparbaev , Olga Fedorova
Biochimica et Biophysica Acta (BBA) - General Subjects, 2014, 1840 (1), pp.387-395. ⟨10.1016/j.bbagen.2013.09.035⟩
Article dans une revue hal-02393729v1
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Pre-steady-state kinetic and mutational insights into mechanisms of endo- and exonuclease DNA processing by mutant forms of human AP endonuclease

 Artemiy Bakman , Alexander Ishchenko , Murat Saparbaev , Olga Fedorova , Nikita Kuznetsov
Biochimica et Biophysica Acta (BBA) - General Subjects, 2022, 1866 (12), pp.130198. ⟨10.1016/j.bbagen.2022.130198⟩
Article dans une revue hal-03858673v1
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TET2-mediated 5-hydroxymethylcytosine induces genetic instability and mutagenesis

 Emna Mahfoudhi , Ibtissam A Talhaoui , Xenia Cabagnols , Véronique Della Valle , Lise Secardin , et al.
DNA Repair, 2016, 43, pp.78 - 88. ⟨10.1016/j.dnarep.2016.05.031⟩
Article dans une revue pasteur-01405648v1
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Highly Mutagenic Exocyclic DNA Adducts Are Substrates for the Human Nucleotide Incision Repair Pathway

 Paulina Prorok , Christine Saint-Pierre , Didier Gasparutto , Olga Fedorova , Alexander Ishchenko , et al.
PLoS ONE, 2012, 7 (12), pp.e51776. ⟨10.1371/journal.pone.0051776⟩
Article dans une revue hal-02368498v1
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Common Kinetic Mechanism of Abasic Site Recognition by Structurally Different Apurinic/Apyrimidinic Endonucleases

 Alexandra A Kuznetsova , Svetlana I Senchurova , Alexander Ishchenko , Murat A Saparbaev , Olga S Fedorova , et al.
International Journal of Molecular Sciences, 2021, 22 (16), pp.8874. ⟨10.3390/ijms22168874⟩
Article dans une revue hal-03432659v1

Direct DNA Lesion Reversal and Excision Repair in Escherichia coli

 Sophie Couvé , Jacques Laval , Erlan Ramanculov , Olga Fedorova , Alexander Ishchenko , et al.
EcoSal Plus, 2013, 5 (2), ⟨10.1128/ecosalplus.7.2.4⟩
Article dans une revue hal-02393792v1
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Characterization of biochemical properties of an apurinic/apyrimidinic endonuclease from Helicobacter pylori

 Aigerim Turgimbayeva , Sailau Abeldenov , Dmitry Zharkov , Alexander Ishchenko , Yerlan Ramankulov , et al.
PLoS ONE, 2018, 13 (8), pp.e0202232. ⟨10.1371/journal.pone.0202232⟩
Article dans une revue hal-02322329v1

Uncoupling of the base excision and nucleotide incision repair pathways reveals their respective biological roles.

 Alexander A Ishchenko , Eric Deprez , Andrei V. Maksimenko , Jean-Claude Brochon , Patrick Tauc , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (8), pp.2564-9. ⟨10.1073/pnas.0508582103⟩
Article dans une revue hal-00216010v1

The major human AP endonuclease (Ape1) is involved in the nucleotide incision repair pathway.

 Laurent Gros , Alexander A Ishchenko , Hiroshi Ide , Rhoderick H Elder , Murat K Saparbaev
Nucleic Acids Research, 2004, 32 (1), pp.73-81. ⟨10.1093/nar/gkh165⟩
Article dans une revue hal-00277634v1

A New DNA Break Repair Pathway Involving PARP3 and Base Excision Repair Proteins

 E. Belousova , M. Kutuzov , P. Ivankina , Alexander Ishchenko , O. Lavrik
Доклады Академии Наук / Doklady Biochemistry and Biophysics, 2018, 482 (1), pp.233-237. ⟨10.1134/S1607672918050010⟩
Article dans une revue hal-02395450v1

Insight into DNA substrate specificity of PARP1 catalyzed DNA poly(ADP-ribosyl)ation

 Elie Matta , Assel Kiribayeva , Bekbolat Khassenov , Alexander Ishchenko
PARP 2019 : New avenues in basic and translational PARP research, May 2019, Budapest, Hungary
Communication dans un congrès hal-03301638v1

Functional variants of human APE1 rescue the DNA repair defects of the yeast AP endonuclease/3′-diesterase-deficient strain

 Zhiqiang Wang , Emily Ayoub , Abdelghani Mazouzi , Inga Grin , Alexander Ishchenko , et al.
DNA Repair, 2014, 22, pp.53-66. ⟨10.1016/j.dnarep.2014.07.010⟩
Article dans une revue hal-02393647v1

Pre-steady-state kinetic analysis of damage recognition by human single-strand selective monofunctional uracil-DNA glycosylase SMUG1

 Alexandra Kuznetsova , Danila Iakovlev , Inna Misovets , Alexander Ishchenko , Murat Saparbaev , et al.
Molecular BioSystems, 2017, 13 (12), pp.2638-2649. ⟨10.1039/c7mb00457e⟩
Article dans une revue hal-02393555v1
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Individual Contributions of Amido Acid Residues Tyr122, Ile168, and Asp173 to the Activity and Substrate Specificity of Human DNA Dioxygenase ABH2

 Anastasiia T Davletgildeeva , Timofey E Tyugashev , Mingxing Zhao , Nikita A Kuznetsov , Alexander A Ishchenko , et al.
Cells, 2023, 12 (14), pp.1839. ⟨10.3390/cells12141839⟩
Article dans une revue hal-04289624v1
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Characterization of DNA ADP-ribosyltransferase activities of PARP2 and PARP3: new insights into DNA ADP-ribosylation

 Gabriella Zarkovic , Ekaterina A Belousova , Ibtissam Talhaoui , Christine Saint-Pierre , Mikhail M Kutuzov , et al.
Nucleic Acids Research, 2018, 46 (5), pp.2417 - 2431. ⟨10.1093/nar/gkx1318⟩
Article dans une revue hal-03423702v1

Dynamics and Conformational Changes in Human NEIL2 DNA Glycosylase Analyzed by Hydrogen/Deuterium Exchange Mass Spectrometry

 Polina Zhdanova , Alexander Ishchenko , Alexander Chernonosov , Dmitry Zharkov , Vladimir Koval
Journal of Molecular Biology, 2022, 434 (2), pp.167334. ⟨10.1016/j.jmb.2021.167334⟩
Article dans une revue hal-03859313v1
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Conformational Dynamics of Human ALKBH2 Dioxygenase in the Course of DNA Repair as Revealed by Stopped-Flow Fluorescence Spectroscopy

 Lyubov Yu. Kanazhevskaya , Denis Smyshliaev , Nadezhda Timofeyeva , Alexander Ishchenko , Murat Saparbaev , et al.
Molecules, 2022, 27 (15), pp.4960. ⟨10.3390/molecules27154960⟩
Article dans une revue hal-03858651v1

New Insights in the Removal of the Hydantoins, Oxidation Product of Pyrimidines, via the Base Excision and Nucleotide Incision Repair Pathways

 Modesto Redrejo-Rodríguez , Christine Saint-Pierre , Sophie Couvé , Abdelghani Mazouzi , Alexander Ishchenko , et al.
PLoS ONE, 2011, 6 (7), pp.e21039. ⟨10.1371/journal.pone.0021039⟩
Article dans une revue cea-02074458v1
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The role of the N-terminal domain of human apurinic/apyrimidinic endonuclease 1, APE1, in DNA glycosylase stimulation

 Olga Kladova , Milena Bazlekowa-Karaban , Sonia Baconnais , Olivier Pietrement , Alexander Ishchenko , et al.
DNA Repair, 2018, 64, pp.10-25. ⟨10.1016/j.dnarep.2018.02.001⟩
Article dans une revue hal-02322373v1
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Comparative Analysis of Exo- and Endonuclease Activities of APE1-like Enzymes

 Anastasiia Davletgildeeva , Alexandra Kuznetsova , Darya Novopashina , Alexander Ishchenko , Murat Saparbaev , et al.
International Journal of Molecular Sciences, 2022, 23 (5), pp.2869. ⟨10.3390/ijms23052869⟩
Article dans une revue hal-03859362v1

Pre-steady-state fluorescence analysis of damaged DNA transfer from human DNA glycosylases to AP endonuclease APE1

 Alexandra Kuznetsova , Nikita Kuznetsov , Alexander Ishchenko , Murat Saparbaev , Olga Fedorova
Biochimica et Biophysica Acta (BBA) - General Subjects, 2014, 1840 (10), pp.3042-3051. ⟨10.1016/j.bbagen.2014.07.016⟩
Article dans une revue hal-02393724v1

The major Arabidopsis thaliana apurinic/apyrimidinic endonuclease, ARP is involved in the plant nucleotide incision repair pathway

 Zhiger Akishev , Sabira Taipakova , Botagoz Joldybayeva , Caroline Zutterling , Izat Smekenov , et al.
DNA Repair, 2016, 48, pp.30-42. ⟨10.1016/j.dnarep.2016.10.009⟩
Article dans une revue hal-02393578v1

Insight into mechanisms of 3'-5' exonuclease activity and removal of bulky 8,5'-cyclopurine adducts by apurinic/apyrimidinic endonucleases

 A. Mazouzi , A. Vigouroux , B. Aikeshev , P. Brooks , M. Saparbaev , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (33), pp.E3071-E3080. ⟨10.1073/pnas.1305281110⟩
Article dans une revue hal-02393760v1
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Dna is a New Target of Parp3

 E. Belousova , Alexander Ishchenko , O. Lavrik
Scientific Reports, 2018, 8 (1), pp.4176. ⟨10.1038/s41598-018-22673-3⟩
Article dans une revue hal-04530992v1

The Kinetic Mechanism of 3′-5′ Exonucleolytic Activity of AP Endonuclease Nfo from E. coli

 Svetlana Senchurova , Aleksandra Kuznetsova , Alexander Ishchenko , Murat Saparbaev , Olga Fedorova , et al.
Cells, 2022, 11 (19), pp.2998. ⟨10.3390/cells11192998⟩
Article dans une revue hal-03859374v1
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The Arabidopsis thaliana Poly(ADP-Ribose) Polymerases 1 and 2 Modify DNA by ADP-Ribosylating Terminal Phosphate Residues

 Sabira Taipakova , Aigerim Kuanbay , Christine Saint-Pierre , Didier Gasparutto , Yeldar Baiken , et al.
Frontiers in Cell and Developmental Biology, 2020, 8, pp.606596. ⟨10.3389/fcell.2020.606596⟩
Article dans une revue hal-03432679v1
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Data on PAGE analysis and MD simulation for the interaction of endonuclease Apn1 from Saccharomyces cerevisiae with DNA substrates containing 5,6-dihydrouracyl and 2-aminopurine

 Elena Dyakonova , Vladimir V Koval , Alexander A Lomzov , Alexander Ishchenko , Olga A Fedorova
Data in Brief, 2018, 20, pp.1515-1524. ⟨10.1016/j.dib.2018.09.007⟩
Article dans une revue hal-02389137v1

7,8-dihydro-8-oxoadenine, a highly mutagenic adduct, is repaired by Escherichia coli and human mismatch-specific uracil/thymine-DNA glycosylases

 Ibtissam Talhaoui , Sophie Couvé , Alexander Ishchenko , Christophe Kunz , Primo Schär , et al.
Nucleic Acids Research, 2013, 41 (2), pp.912-923. ⟨10.1093/nar/gks1149⟩
Article dans une revue hal-02393748v1
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