Recherche - Archive ouverte HAL

33 résultats

	Pour les 33 documents Envoyer sur ORCID RSS ATOM Exporter BibTeX XML-TEI CSV RTF EndNote PDF HTML Export avancé	Page : Page précédente 1 2 Page suivante	triés par Pertinence Auteur A→Z Auteur Z→A Titre A→Z Titre Z→A Date de publication croissante Date de publication décroissante Date de dépôt croissante Date de dépôt décroissante

		Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis Amandine Cartier-Michaud , Anne-Laure Bailly , Stéphane Betzi , Xiaoli Shi , Jean-Claude Lissitzky , et al. PLoS Genetics, 2017, 13 (6), ⟨10.1371/journal.pgen.1006803⟩ Article dans une revue hal-01542697v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		In silico molecular target prediction unveils mebendazole as a potent MAPK14 inhibitor Jeremy Ariey‐bonnet , Kendall Carrasco , Marion Le Grand , Laurent Hoffer , Stéphane Betzi , et al. Molecular Oncology, 2020, 14, pp.3083 - 3099. ⟨10.1002/1878-0261.12810⟩ Article dans une revue hal-02989358v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Discovery of Small-Molecule Inhibitors of the PTK7/β-Catenin Interaction Targeting the Wnt Signaling Pathway in Colorectal Cancer Laetitia Ganier , Stéphane Betzi , Carine Derviaux , Philippe Roche , Charlotte Dessaux , et al. ACS Chemical Biology, 2022, 17 (5), pp.1061-1072. ⟨10.1021/acschembio.1c00826⟩ Article dans une revue hal-03817750v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Integrated Strategy for Lead Optimization Based on Fragment Growing: The Diversity-Oriented-Target-Focused-Synthesis Approach Laurent Hoffer , Yuliia Voitovich , Brigitt Raux , Kendall Carrasco , Christophe Muller , et al. Journal of Medicinal Chemistry, 2018, 61 (13), pp.5719-5732. ⟨10.1021/acs.jmedchem.8b00653⟩ Article dans une revue hal-02067797v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Editorial. Françoise Ochsenbein , Xavier Morelli , Chandra Verma Progress in Biophysics and Molecular Biology, 2015, 119 (1), pp.1 Article dans une revue hal-01201641v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Fr-PPIChem: An Academic Compound Library Dedicated to Protein-Protein Interactions Nicolas Bosc , Christophe Muller , Laurent Hoffer , David Lagorce , Stéphane Bourg , et al. ACS Chemical Biology, 2020, 15 (6), pp.1566-1574. ⟨10.1021/acschembio.0c00179⟩ Article dans une revue hal-02569625v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Rôle en cancérologie et ciblage du récepteur à activité tyrosine kinase PTK7 Laetitia Ganier , Xavier Morelli , Jean-Paul Borg Médecine/Sciences, 2020, ⟨10.1051/medsci/2020197⟩ Article dans une revue hal-03152194v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		2P2Idb v2: update of a structural database dedicated to orthosteric modulation of protein–protein interactions Marie-Jeanne Basse , Stéphane Betzi , Xavier Morelli , Philippe Roche Database - The journal of Biological Databases and Curation, 2016, 2016, pp.6. ⟨10.1093/database/baw007⟩ Article dans une revue hal-01307114v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Optimization of a fragment linking hit toward Dengue and Zika virus NS5 methyltransferases inhibitors Jessica Hernandez , Laurent Hoffer , Bruno Coutard , Gilles Quérat , Philippe Roche , et al. European Journal of Medicinal Chemistry, 2019, 161 (4), pp.323-333. ⟨10.1016/j.ejmech.2018.09.056⟩ Article dans une revue inserm-02378768v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Identification of a Src kinase SH3 binding site in the C-terminal domain of the human ErbB2 receptor tyrosine kinase. Olivier Bornet , Matthieu Nouailler , Michaël Feracci , Corinne Sebban-Kreuzer , Deborah Byrne , et al. FEBS Letters, 2014, 588 (12), pp.2031--6. ⟨10.1016/j.febslet.2014.04.029⟩ Article dans une revue hal-01458194v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Mutational analysis of the DOK2 haploinsufficient tumor suppressor gene in chronic myelomonocytic leukemia (CMML). Emilie Coppin , Véronique Gelsi-Boyer , Xavier Morelli , Nathalie Cervera , Anne Murati , et al. Leukemia, 2014, 29 (2), pp.500-2. ⟨10.1038/leu.2014.288⟩ Article dans une revue inserm-01069773v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		The NANOTUMOR consortium - Towards the Tumor Cell Atlas Florent Colin , Kristine Schauer , Ali Hamiche , Pierre Martineau , Jean-Paul Borg , et al. Biology of the Cell, 2021, 113 (6), pp.272-280. ⟨10.1111/boc.202000135⟩ Article dans une revue hal-03169719v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Alteration of a Single Tryptophan Residue of the Cellulose-binding Domain Blocks Secretion of the Erwinia chrysanthemi Cel5 Cellulase (ex-EGZ) via the Type II System Virginie Chapon , Helen D Simpson , Xavier Morelli , Emmanuel Brun , Frederic Barras Journal of Molecular Biology, 2000, 303, pp.117-123. ⟨10.1006/jmbi.2000.4103⟩ Article dans une revue istex hal-01560905v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology Kahina Hammam , Magali Saez-Ayala , Etienne Rebuffet , Laurent Gros , Sophie Lopez , et al. Nature Communications, 2017, 8 (1), ⟨10.1038/s41467-017-01582-5⟩ Article dans une revue hal-01643359v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Interaction between the C-terminal domains of N and P proteins of measles virus investigated by NMR. Cedric Bernard , Stéphane Gely , Jean-Marie Bourhis , Xavier Morelli , Sonia Longhi , et al. FEBS Letters, 2009, 583 (7), pp.1084-9. ⟨10.1016/j.febslet.2009.03.004⟩ Article dans une revue hal-00473784v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Crystal structure of the vaccinia virus DNA polymerase holoenzyme subunit D4 in complex with the A20 N-terminal domain Céline Contesto-Richefeu , Nicolas Tarbouriech , Xavier Brazzolotto , Stéphane Betzi , Xavier Morelli , et al. PLoS Pathogens, 2014, 10 (3), pp.e1003978. ⟨10.1371/journal.ppat.1003978⟩ Article dans une revue hal-01132360v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Aminoacylase 1-catalysed deacetylation of bioactives epoxides mycotoxin-derived mercapturates; 3,4-epoxyprecocenes as models of cytotoxic epoxides Pierre Stocker , Jean Michel Brunel , Leandro De Rezende , Antonia Tavares-Do Amaral , Xavier Morelli , et al. Biochimie, 2012, 94 (8), pp.1668-1675. ⟨10.1016/j.biochi.2012.01.006⟩ Article dans une revue istex hal-01460427v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		GFscore: a general nonlinear consensus scoring function for high-throughput docking. Stéphane Betzi , Karsten Suhre , Bernard Chétrit , Françoise Guerlesquin , Xavier Morelli Journal of Chemical Information and Modeling, 2006, 46 (4), pp.1704-12. ⟨10.1021/ci0600758⟩ Article dans une revue istex hal-00475665v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Identification of allosteric inhibitors blocking the hepatitis C virus polymerase NS5B in the RNA synthesis initiation step. Stéphane Betzi , Cécilia Eydoux , Cécile Bussetta , Marilyne Blemont , Pieter Leyssen , et al. Antiviral Research, 2009, 84 (1), pp.48-59. ⟨10.1016/j.antiviral.2009.06.009⟩ Article dans une revue istex hal-00418783v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Structural recognition mechanisms between human Src homology domain 3 (SH3) and ALG-2-interacting protein X (Alix) Xiaoli Shi , Stéphane Betzi , Adrien Lugari , Sandrine Opi , Audrey Restouin , et al. FEBS Letters, 2012, 586, pp.1759-1764. ⟨10.1016/j.febslet.2012.05.017⟩ Article dans une revue hal-00717171v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Protein protein interaction inhibition (2P2I) combining high throughput and virtual screening: Application to the HIV-1 Nef protein. Stéphane Betzi , Audrey Restouin , Sandrine Opi , Stefan T Arold , Isabelle Parrot , et al. Proceedings of the National Academy of Sciences of the United States of America, 2007, 104 (49), pp.19256-61. ⟨10.1073/pnas.0707130104⟩ Article dans une revue hal-00473817v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		A specific protein disorder catalyzer of HIV-1 Nef Adrien Lugari , Sebastian Breuer , Thibault Coursindel , Sandrine Opi , Audrey Restouin , et al. Bioorganic and Medicinal Chemistry, 2011, 19, pp.7401-7406. ⟨10.1016/j.bmc.2011.10.051⟩ Article dans une revue istex hal-00662295v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		CRCM5484: A BET- BDII Selective Compound With Differential Anti-Leukemic Drug Modulation Kendall Carrasco , Camille Montersino , Carine Derviaux , Magali Saez-Ayala , Laurent Hoffer , et al. Journal of Medicinal Chemistry, 2022, pp.acs.jmedchem.1c02168. ⟨10.1021/acs.jmedchem.1c02168⟩ Article dans une revue hal-03624836v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia Magali Saez-Ayala , Laurent Hoffer , Sébastien Abel , Khaoula Ben Yaala , Benoit Sicard , et al. Nature Communications, 2023, 14 (1), pp.3079. ⟨10.1038/s41467-023-38668-2⟩ Article dans une revue hal-04237671v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Identification and biophysical assessment of the molecular recognition mechanisms between the human hemopoietic cell kinase Src homology domain 3 and ALG-2-interacting protein X Xiaoli Shi , Sandrine Opi , Adrien Lugari , Audrey Restouin , Thibault Coursindel , et al. Biochemical Journal, 2010, 431 (1), pp.93-102. ⟨10.1042/BJ20100314⟩ Article dans une revue hal-00517249v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		CovaDOTS: In Silico Chemistry-Driven Tool to Design Covalent Inhibitors Using a Linking Strategy Laurent Hoffer , Magali Saez-Ayala , Dragos Horvath , Alexandre Varnek , Xavier Morelli , et al. Journal of Chemical Information and Modeling, 2019, 59 (4), pp.1472-1485. ⟨10.1021/acs.jcim.8b00960⟩ Article dans une revue hal-02145507v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Solution structure of HndAc: a thioredoxin-like domain involved in the NADP-reducing hydrogenase complex. Matthieu Nouailler , Xavier Morelli , Olivier Bornet , Bernard Chetrit , Zorah Dermoun , et al. Protein Science, 2006, 15 (6), pp.1369-78. ⟨10.1110/ps.051916606⟩ Article dans une revue hal-00475666v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Structural and Genetic Analyses Reveal a Key Role in Prophage Excision for the TorI Response Regulator Inhibitor Latifa Elantak , Mireille Ansaldi , Francoise Guerlesquin , Vincent Méjean , Xavier Morelli Journal of Biological Chemistry, 2005, 280 (44), pp.36802-36808. ⟨10.1074/jbc.m507409200⟩ Article dans une revue hal-02018141v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Chemistry-driven Hit-to-lead Optimization Guided by Structure-based Approaches Laurent Hoffer , Christophe Muller , Philippe Roche , Xavier Morelli Molecular Informatics, 2018, 37 (9-10), pp.1800059. ⟨10.1002/minf.201800059⟩ Article dans une revue hal-02145522v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Stereoselective synthesis of original spirolactams displaying promising folded structures. Guilhem Chaubet , Thibault Coursindel , Xavier Morelli , Stéphane Betzi , Philippe Roche , et al. Organic & Biomolecular Chemistry, 2013, 11 (28), pp.4719-26. ⟨10.1039/c3ob40643a⟩ Article dans une revue hal-00871067v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More

Filtrer vos résultats

Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis

In silico molecular target prediction unveils mebendazole as a potent MAPK14 inhibitor

Discovery of Small-Molecule Inhibitors of the PTK7/β-Catenin Interaction Targeting the Wnt Signaling Pathway in Colorectal Cancer

Integrated Strategy for Lead Optimization Based on Fragment Growing: The Diversity-Oriented-Target-Focused-Synthesis Approach

Editorial.

Fr-PPIChem: An Academic Compound Library Dedicated to Protein-Protein Interactions

Rôle en cancérologie et ciblage du récepteur à activité tyrosine kinase PTK7

2P2Idb v2: update of a structural database dedicated to orthosteric modulation of protein–protein interactions

Optimization of a fragment linking hit toward Dengue and Zika virus NS5 methyltransferases inhibitors

Identification of a Src kinase SH3 binding site in the C-terminal domain of the human ErbB2 receptor tyrosine kinase.

Mutational analysis of the DOK2 haploinsufficient tumor suppressor gene in chronic myelomonocytic leukemia (CMML).

The NANOTUMOR consortium - Towards the Tumor Cell Atlas

Alteration of a Single Tryptophan Residue of the Cellulose-binding Domain Blocks Secretion of the Erwinia chrysanthemi Cel5 Cellulase (ex-EGZ) via the Type II System

Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology

Interaction between the C-terminal domains of N and P proteins of measles virus investigated by NMR.

Crystal structure of the vaccinia virus DNA polymerase holoenzyme subunit D4 in complex with the A20 N-terminal domain

Aminoacylase 1-catalysed deacetylation of bioactives epoxides mycotoxin-derived mercapturates; 3,4-epoxyprecocenes as models of cytotoxic epoxides

GFscore: a general nonlinear consensus scoring function for high-throughput docking.

Identification of allosteric inhibitors blocking the hepatitis C virus polymerase NS5B in the RNA synthesis initiation step.

Structural recognition mechanisms between human Src homology domain 3 (SH3) and ALG-2-interacting protein X (Alix)

Protein protein interaction inhibition (2P2I) combining high throughput and virtual screening: Application to the HIV-1 Nef protein.

A specific protein disorder catalyzer of HIV-1 Nef

CRCM5484: A BET- BDII Selective Compound With Differential Anti-Leukemic Drug Modulation

From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia

Identification and biophysical assessment of the molecular recognition mechanisms between the human hemopoietic cell kinase Src homology domain 3 and ALG-2-interacting protein X

CovaDOTS: In Silico Chemistry-Driven Tool to Design Covalent Inhibitors Using a Linking Strategy

Solution structure of HndAc: a thioredoxin-like domain involved in the NADP-reducing hydrogenase complex.

Structural and Genetic Analyses Reveal a Key Role in Prophage Excision for the TorI Response Regulator Inhibitor

Chemistry-driven Hit-to-lead Optimization Guided by Structure-based Approaches

Stereoselective synthesis of original spirolactams displaying promising folded structures.