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A p53 score derived from TP53 CRISPR/Cas9 HMCLs predicts survival and reveals major role of BAX in BH3 mimetics response
Romane Durand
,
Géraldine Descamps
,
Christelle Dousset
,
Céline Bellanger
,
Sophie Maïga
,
et al.
Article dans une revue
hal-04359884v1
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Targeting Oxidative Stress With Auranofin or Prima-1Met to Circumvent p53 or Bax/Bak Deficiency in Myeloma Cells
Benoit Tessoulin
,
Géraldine Descamps
,
Christelle Dousset
,
Martine Amiot
,
Catherine Pellat-Deceunynck
Article dans une revue
inserm-02055153v1
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TLR9 Ligand Induces the Generation of CD20+ Plasmablasts and Plasma Cells from CD27+ Memory B-Cells
Alexandrine Geffroy-Luseau
,
David Chiron
,
Géraldine Descamps
,
Gaëtan Jégo
,
Martine Amiot
,
et al.
Article dans une revue
inserm-03290331v1
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CARD11 gain of function upregulates BCL2A1 and promotes resistance to targeted therapies combination in B-cell lymphoma
Salomé Decombis
,
Céline Bellanger
,
Yannick Le Bris
,
Candice Madiot
,
Jane Jardine
,
et al.
Article dans une revue
hal-04195394v1
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p53 regulates CD46 expression and measles virus infection in myeloma cells
Anne Lok
,
Géraldine Descamps
,
Benoit Tessoulin
,
David Chiron
,
Marion Eveillard
,
et al.
Article dans une revue
inserm-01957487v1
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Biological rational for sequential targeting of Bruton tyrosine kinase and Bcl-2 to overcome CD40-induced ABT-199 resistance in mantle cell lymphoma
David Chiron
,
Christelle Dousset
,
Carole Brosseau
,
Cyrille Touzeau
,
Sophie Maïga
,
et al.
Article dans une revue
inserm-02534385v1
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Curcumin induces cell death of the main molecular myeloma subtypes, particularly the poor prognosis subgroups
Patricia Gomez-Bougie
,
Maxime Halliez
,
Sophie Maïga
,
Catherine Godon
,
Charlotte Kervoëlen
,
et al.
Article dans une revue
inserm-02534388v1
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Decitabine and Melphalan Fail to Reactivate p73 in p53 Deficient Myeloma Cells
Pierre-Samuel Gillardin
,
Géraldine Descamps
,
Sophie Maiga
,
Benoit Tessoulin
,
Hanane Djamai
,
et al.
Article dans une revue
inserm-01691503v1
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The origin of the plasma-cell heterogeneity
Catherine Pellat-Deceunynck
,
Thierry Defrance
Frontiers in Immunology, 2015, 6
Article dans une revue
inserm-01820475v1
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Toll-like receptors: lessons to learn from normal and malignant human B cells
David Chiron
,
Isabelle Bekeredjian-Ding
,
Catherine Pellat-Deceunynck
,
Régis Bataille
,
Gaetan Jego
Article dans une revue
inserm-02459027v1
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RITA (Reactivating p53 and Inducing Tumor Apoptosis) is efficient against TP53 abnormal myeloma cells independently of the p53 pathway
Sylvanie Surget
,
Géraldine Descamps
,
Carole Brosseau
,
Vincent Normant
,
Sophie Maïga
,
et al.
Article dans une revue
inserm-03290484v1
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A Functional, New Short Isoform of Death Receptor 4 in Ewing's Sarcoma Cell Lines May be Involved in TRAIL Sensitivity/Resistance Mechanisms
Gaëlle Picarda
,
Sylvanie Surget
,
Romain Guiho
,
Stéphane Teletchea
,
Martine Berreur
,
et al.
Article dans une revue
inserm-02438684v1
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Differential expression of Bcl-2 in human plasma cell disorders according to proliferation status and malignancy
Denis Puthier
,
Catherine Pellat-Deceunynck
,
S. Barille
,
N. Robillard
,
M. J. Rapp
,
et al.
Leukemia, 1999, 13 (2), pp.289--294
Article dans une revue
hal-01595832v1
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Targeting Oxidative Stress With Auranofin or Prima-1Met to Circumvent p53 or Bax/Bak Deficiency in Myeloma Cells
Benoit Tessoulin
,
Geraldine Descamps
,
Christelle Dousset
,
Martine Amiot
,
Catherine Pellat-Deceunynck
Article dans une revue
inserm-04154942v1
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CSF1R and BTK inhibitions as novel strategies to disrupt the dialogue between mantle cell lymphoma and macrophages
Antonin Papin
,
Benoit Tessoulin
,
Céline Bellanger
,
Anne Moreau
,
Yannick Le Bris
,
et al.
Leukemia, In press, Epub ahead of print
Article dans une revue
inserm-02081007v1
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Heat shock factor 1 is a potent therapeutic target for enhancing the efficacy of treatments for multiple myeloma with adverse prognosis
Sophie Bustany
,
Julie Cahu
,
Géraldine Descamps
,
Catherine Pellat-Deceunynck
,
Brigitte Sola
Article dans une revue
inserm-01237704v1
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The REFRACT-LYMA cohort study: a French observational prospective cohort study of patients with mantle cell lymphoma.
Matthieu Hanf
,
David Chiron
,
Sophie de Visme
,
Cyrille Touzeau
,
Hervé Maisonneuve
,
et al.
Article dans une revue
hal-01524145v1
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Dual targeting of BCL2 and MCL1 rescues myeloma cells resistant to BCL2 and MCL1 inhibitors associated with the formation of BAX/ BAK hetero-complexes
Carolane Seiller
,
Sophie Maiga
,
Cyrille Touzeau
,
Céline Bellanger
,
Charlotte Kervoëlen
,
et al.
Article dans une revue
inserm-02563554v1
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Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathways
Benoit Tessoulin
,
Agnès Moreau-Aubry
,
Géraldine Descamps
,
Patricia Gomez-Bougie
,
Sophie Maiga
,
et al.
Article dans une revue
inserm-01958772v1
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Development of ISB 1442, a CD38 and CD47 bispecific biparatopic antibody innate cell modulator for the treatment of multiple myeloma
C Grandclément
,
C Estoppey
,
E Dheilly
,
M Panagopoulou
,
T Monney
,
et al.
Article dans une revue
hal-04496386v1
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Pre-clinical characterization of ISB 1342, a CD38xCD3 T-cell engager for relapsed/refractory multiple myeloma
Blandine Pouleau
,
Carole Estoppey
,
Perrine Suere
,
Emilie Nallet
,
Amélie Laurendon
,
et al.
Article dans une revue
hal-04240669v1
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p53 dysregulation in B-cell malignancies: More than a single gene in the pathway to hell
Benoit Tessoulin
,
Marion Eveillard
,
Anne Lok
,
David Chiron
,
Philippe Moreau
,
et al.
Article dans une revue
inserm-01493742v1
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Mcl-1L cleavage is involved in TRAIL-R1– and TRAIL-R2–mediated apoptosis induced by HGS-ETR1 and HGS-ETR2 human mAbs in myeloma cells
Emmanuelle Menoret
,
Patricia Gomez-Bougie
,
Alexandrine Geffroy-Luseau
,
Sylvanne Daniels
,
Philippe Moreau
,
et al.
Article dans une revue
inserm-03290205v1
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BH3 profiling as a tool to identify acquired resistance to venetoclax in multiple myeloma
Christelle Dousset
,
Sophie Maïga
,
Patricia Gomez-Bougie
,
Joy Le Coq
,
Cyrille Touzeau
,
et al.
Article dans une revue
inserm-01353369v1
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Generation and characterization of novel anti-DR4 and anti-DR5 antibodies developed by genetic immunization
Agathe Dubuisson
,
Cécile Favreau
,
Eric Fourmaux
,
Sabrina Lareure
,
Rafael Rodrigues-Saraiva
,
et al.
Article dans une revue
inserm-02006230v1
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A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines.
Jérôme Moreaux
,
Bernard Klein
,
Régis Bataille
,
Géraldine Descamps
,
Sophie Maïga
,
et al.
Article dans une revue
inserm-00550232v1
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Myeloma Cell Self-Renewal Depends on JAG2 Expression and Is Mediated by IGF1 or SCF Loop
David Chiron
,
Sophie Maiga
,
Géraldine Descamps
,
Severine Marionneau-Lambot
,
Catherine Pellat-Deceunynck
Communication dans un congrès
inserm-02459063v1
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The REFRACT-LYMA cohort study: a French observational prospective cohort study of patients with mantle cell lymphoma
Matthieu Hanf
,
David Chiron
,
Sophie de Visme
,
Cyrille Touzeau
,
Hervé Maisonneuve
,
et al.
Article dans une revue
inserm-01381110v1
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The MYRACLE protocol study: a multicentric observational prospective cohort study of patients with multiple myeloma
Lina Benaniba
,
Benoit Tessoulin
,
Sabrina Trudel
,
Catherine Pellat-Deceunynck
,
Martine Amiot
,
et al.
Article dans une revue
inserm-02290127v1
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BH3-mimetic toolkit guides the respective use of BCL2 and MCL1 BH3-mimetics in myeloma treatment
Patricia Gomez-Bougie
,
Sophie Maïga
,
Benoit Tessoulin
,
Jessie Bourcier
,
Antoine Bonnet
,
et al.
Article dans une revue
inserm-01900681v1
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