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Carnitine deficiency induces a short QT syndrome

Julien Roussel , François Labarthe , Jérôme Thireau , Fabio Ferro , Charlotte Farah , et al.
Heart Rhythm, 2016, 13 (1), pp.165 - 174. ⟨10.1016/j.hrthm.2015.07.027⟩
Article dans une revue hal-01786235v1
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Palmitoyl-carnitine increases RyR2 oxidation and sarcoplasmic reticulum Ca2+ leak in cardiomyocytes: Role of adenine nucleotide translocase

Julien Roussel , Jérôme Thireau , Cyril Brenner , Nathalie Saint , Valérie Scheuermann , et al.
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2015, 1852 (5), pp.749-758. ⟨10.1016/j.bbadis.2015.01.011⟩
Article dans une revue hal-01759172v1
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Short-term variability in QT interval and ventricular arrhythmias induced by dofetilide are dependent on high-frequency autonomic oscillations

Pascal Champeroux , Jérôme Thireau , S. Judé , C Laigot-Barbé , A. Maurin , et al.
British Journal of Pharmacology, 2015, 172 (11), pp.2878 - 2891. ⟨10.1111/bph.13093⟩
Article dans une revue hal-01764951v1
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Two sides of the same coin: NEO-PUFAs in Rett syndrome and post-infarction cardiac arrhythmias

Marie Demion , Camille Oger , Claire Vigor , Jérôme Thireau , Jean-Yves Le Guennec , et al.
European Journal of Lipid Science and Technology, 2017, Lipid Oxidation and Antioxidants, 119 (6), pp.1600320. ⟨10.1002/ejlt.201600320⟩
Article dans une revue hal-01830138v1

Non-anti-mitotic concentrations of taxol reduce breast cancer cell invasiveness

Truong-An Tran , Ludovic Gillet , Sébastien Roger , Pierre Besson , Edward White , et al.
Biochemical and Biophysical Research Communications, 2009, 379 (2), pp.304 - 308. ⟨10.1016/j.bbrc.2008.12.073⟩
Article dans une revue istex hal-01822231v1

The SK3/KCa2.3 potassium channel is a new cellular target for edelfosine

P. Potier , C Chantome , V. Joulin , A Girault , S Roger , et al.
British Journal of Pharmacology, 2011, 162 (2), pp.464 - 479. ⟨10.1111/j.1476-5381.2010.01044.x⟩
Article dans une revue hal-01822224v1
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Dietary long-chain omega-3 fatty acids of marine origin: a comparison of their protective effects on coronary heart disease and breast cancers.

Sébastien Judé , Sébastien Roger , Eric Martel , Pierre Besson , Serge Richard , et al.
Progress in Biophysics and Molecular Biology, 2006, 90 (1-3), pp.299-325. ⟨10.1016/j.pbiomolbio.2005.05.006⟩
Article dans une revue inserm-00141884v1
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Voltage-gated sodium channels and cancer: is excitability their primary role?

Sébastien Roger , Ludovic Gillet , Jean-Yves Le Guennec , Pierre Besson
Frontiers in Pharmacology, 2015, 6, pp.152. ⟨10.3389/fphar.2015.00152⟩
Article dans une revue hal-01762815v1
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Biodegradable Polymeric Nanocapsules Prevent Cardiotoxicity of Anti-Trypanosomal Lychnopholide

Renata Tupinambá Branquinho , Jérôme Roy , Charlotte Farah , Giani Martins Garcia , Jean-Yves Le Guennec , et al.
Scientific Reports, 2017, 7, pp.44998. ⟨10.1038/srep44998⟩
Article dans une revue hal-01822213v1

Differential contribution of cardiac sarcomeric proteins in the myofibrillar force response to stretch

Younss Ait Mou , Jean-Yves Le Guennec , Emilio Mosca , Pieter de Tombe , Olivier Cazorla
Pflügers Archiv European Journal of Physiology, 2008, 457 (1), pp.25 - 36. ⟨10.1007/s00424-008-0501-x⟩
Article dans une revue hal-01822232v1
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The Effect of Hypothermia and Osmotic Shock on the Electrocardiogram of Adult Zebrafish

Elodie Arel , Laura Rolland , Jérôme Thireau , Angelo Torrente , Emilie Bechard , et al.
Biology, 2022, 11 (4), pp.603. ⟨10.3390/biology11040603⟩
Article dans une revue hal-03649835v1
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Non-enzymatic lipid mediators, neuroprostanes, exert the antiarrhythmic properties of docosahexaenoic acid

Jérôme Roy , Camille Oger , Jérôme Thireau , Julien Roussel , Olivia Mercier-Touzet , et al.
Free Radical Biology and Medicine, 2015, 86, pp.269 - 278. ⟨10.1016/j.freeradbiomed.2015.04.014⟩
Article dans une revue hal-01753886v1

Differential contribution of cardiac sarcomeric proteins in the myofibrillar force response to stretch

Younss Ait Mou , Jean-Yves Le Guennec , Emilio Mosca , Pieter de Tombe , Olivier Cazorla
Pflügers Archiv European Journal of Physiology, 2008, 457 (1), pp.25 - 36. ⟨10.1007/s00424-008-0501-x⟩
Article dans une revue hal-01824379v1

Association of a functional deficit of the BKCa channel, a synaptic regulator of neuronal excitability, with autism and mental retardation

Frédéric Laumonnier , Sébastien Roger , Pascaline Guerin , Florence Molinari , Ridha M'Rad , et al.
The American Journal of Psychiatry, 2006, 163 (9), pp.1622 - 1629. ⟨10.1176/appi.ajp.163.9.1622⟩
Article dans une revue hal-02658023v1

Length Modulation of Active Force in Rat Cardiac Myocytes: is Titin the Sensor?

Olivier Cazorla , Guy Vassort , Didier Garnier , Jean-Yves Le Guennec
Journal of Molecular and Cellular Cardiology, 1999, 31 (6), pp.1215-1227. ⟨10.1006/jmcc.1999.0954⟩
Article dans une revue istex hal-01824416v1

Interferences of the autonomic nervous system with drug induced QT prolongation: A point to consider in non-clinical safety studies

Pascal Champeroux , Aude Ouillé , Eric Martel , John Sinclair Lawrence Fowler , Anne Maurin , et al.
Journal of Pharmacological and Toxicological Methods, 2010, 61 (3), pp.251 - 263. ⟨10.1016/j.vascn.2010.02.006⟩
Article dans une revue istex hal-01822227v1
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EFFECTS ON L-TYPE CALCIUM CURRENT OF AGENTS INTERFERING WITH THE CYTOSKELETON OF ISOLATED GUINEA-PIG VENTRICULAR MYOCYTES

Caroline Pascarel , Fabien Brette , Olivier Cazorla , Jean-Yves Le Guennec
Experimental Physiology, 1999, 84 (6), pp.1043-1050. ⟨10.1111/j.1469-445X.1999.01876.x⟩
Article dans une revue hal-01824411v1
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The Complex QT/RR Relationship in Mice

Julien Roussel , Pascal Champeroux , Jérôme Roy , Sylvain Richard , J. Fauconnier , et al.
Scientific Reports, 2016, 6 (1), pp.25388. ⟨10.1038/srep25388⟩
Article dans une revue hal-01800835v1
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Activation of Sonic hedgehog signaling in ventricular cardiomyocytes exerts cardioprotection against ischemia reperfusion injuries

Ludovit Paulis , J. Fauconnier , Olivier Cazorla , Jérôme Thireau , Raffaella Soleti , et al.
Scientific Reports, 2015, 5, pp.7983. ⟨10.1038/srep07983⟩
Article dans une revue hal-01392497v1
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Long-chain acylcarnitines regulate the hERG channel.

Fabio Ferro , Aude Ouillé , Truong-An Tran , Pierre Fontanaud , Patrick Bois , et al.
PLoS ONE, 2012, 7 (7), pp.e41686. ⟨10.1371/journal.pone.0041686⟩
Article dans une revue hal-00991850v1

Characterization of cell membrane response to ultrasound activated microbubbles

Truong-An Tran , Jean-Yves Le Guennec , P. Bougnoux , F. Tranquart , A. Bouakaz
IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, 2008, 55 (1), pp.43 - 49. ⟨10.1109/TUFFC.2008.615⟩
Article dans une revue hal-01822233v1

β-Adrenergic blockade combined with subcutaneous B-type natriuretic peptide: a promising approach to reduce ventricular arrhythmia in heart failure?

Jérôme Thireau , Sarah Karam , Stéphanie Roberge , Julien Roussel , Franck Aimond , et al.
Heart, 2014, 100 (11), pp.833 - 841. ⟨10.1136/heartjnl-2013-305167⟩
Article dans une revue hal-01822219v1
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Reply to the Editor—Carnitine and Ventricular Repolarization: A Complex Link?

Julien Roussel , Jérôme Thireau , Charlotte Farah , Jean-Yves Le Guennec , Dominique Babuty
Heart Rhythm, 2016, 13 (8), pp.1760. ⟨10.1016/j.hrthm.2016.04.019⟩
Article dans une revue hal-01802241v1

Methods and pharmaceutical compositions for the cardioprotection

Alain Lacampagne , Jérome Thireau , Olivier Cazorla , Jean-Yves Le Guennec , Jérémy Fauconnier , et al.
France, Patent n° : Non spécifié. 2014
Brevet hal-03276666v1

Length–Tension Relationships of Sub-epicardial and Sub-endocardial Single Ventricular Myocytes from Rat and Ferret Hearts

Olivier Cazorla , Jean-Yves Le Guennec , Ed White
Journal of Molecular and Cellular Cardiology, 2000, 32 (5), pp.735-744. ⟨10.1006/jmcc.2000.1115⟩
Article dans une revue istex hal-01824407v1

TNF- -mediated caspase-8 activation induces ROS production and TRPM2 activation in adult ventricular myocytes

S. Roberge , J. Roussel , Daniel Andersson , Albano C Meli , B. Vidal , et al.
Cardiovascular Research, 2014, 103 (1), pp.90 - 99. ⟨10.1093/cvr/cvu112⟩
Article dans une revue hal-01822218v1
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Ca2+ currents in cardiac myocytes: Old story, new insights.

Fabien Brette , Jérôme Leroy , Jean-Yves Le Guennec , Laurent Sallé
Progress in Biophysics and Molecular Biology, 2006, 91 (1-2), pp.1-82. ⟨10.1016/j.pbiomolbio.2005.01.001⟩
Article dans une revue inserm-00141882v1
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Ranolazine inhibits NaV1.5-mediated breast cancer cell invasiveness and lung colonization

Virginie Driffort , Ludovic Gillet , Emeline Bon , Séverine Marionneau-Lambot , Thibauld Oullier , et al.
Molecular Cancer, 2014, 13 (1), ⟨10.1186/1476-4598-13-264⟩
Article dans une revue hal-01822217v1
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Inter-individual variability and modeling of electrical activity: a possible new approach to explore cardiac safety?

Jean-Yves Le Guennec , Jérôme Thireau , Aude Ouillé , Julien Roussel , Jérôme Roy , et al.
Scientific Reports, 2016, 6 (1), pp.37948. ⟨10.1038/srep37948⟩
Article dans une revue hal-01784408v1
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The high frequency relationship: implications for torsadogenic hERG blockers

P Champeroux , Jean-Yves Le Guennec , S Jude , C Laigot , A Maurin , et al.
British Journal of Pharmacology, 2016, 173 (3), pp.601 - 612. ⟨10.1111/bph.13391⟩
Article dans une revue hal-01782907v1