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Methotrexate effect on immunogenicity and long-term maintenance of adalimumab in axial spondyloarthritis: a multicentric randomised trial

Emilie Ducourau , Theo Rispens , Marine Samain , Emmanuelle Dernis , Fabienne Le Guilchard , et al.
RMD Open : Rheumatic & Musculoskeletal Diseases, 2020, 6 (1), pp.e001047. ⟨10.1136/rmdopen-2019-001047⟩
Article dans une revue hal-03244823v1

Mycophenolate mofetil in patients with systemic lupus erythematosus: a prospective pharmacokinetic study

Melanie Roland , Christelle Barbet , Gilles Paintaud , Charlotte Magdelaine-Beuzelin , Elisabeth Diot , et al.
Lupus, 2009, 18 (5), pp.441-447
Article dans une revue hal-00616925v1

Development and validation of an ELISA to study panitumumab pharmacokinetics

Celine Desvignes , Christophe Passot , David Ternant , Morgane Caulet , Caroline Guérineau , et al.
Bioanalysis, 2018, 10 (4), pp.205-214. ⟨10.4155/bio-2016-0292⟩
Article dans une revue hal-02372863v1

Mycophenolate mofetil in patients with systemic lupus erythematosus : a prospective pharmacokinetic study.

Gilles Paintaud , Charlotte Magdelaine-Beuzelin , M. Roland , C. Barbet , E. Diot , et al.
Lupus, 2009, 18, pp.441-447
Article dans une revue hal-00375656v1

THE ROLE OF CLINICAL PHARMACOLOGY TO EXPLORE AND SUPPORT THE USE OF NEW DRUGS

Gilles Paintaud
Basic and Clinical Pharmacology and Toxicology, 2011, 109, pp.54-54
Article dans une revue hal-00616730v1

Alterations in the Intestinal Microbiome (Dysbiosis) as a Predictor of Relapse After Infliximab Withdrawal in Crohn's Disease.

Sylvie Rajca , Virginie Grondin , Edouard Louis , Gwenola Vernier-Massouille , Jean-Charle Grimaud , et al.
Inflammatory Bowel Diseases, 2014, 20 (6), pp.978-986. ⟨10.1097/MIB.0000000000000036⟩
Article dans une revue hal-00986861v1

Study of anti TNF-alpha biopharmaceuticals kinetic properties by surface plasmon resonance

D. Mulleman , Marie-Christine Maurel , M. Ohresser , H. Watier , G. Paintaud , et al.
Annual European Congress of Rheumatology, Jun 2007, Barcelone, Spain
Communication dans un congrès hal-02755684v1

Influence of immunogenicity on long-term maintenance of adalimumab in spondyloarthritis

M Samain , E Ducourau , T Rispens , E. Dernis , F Le Guilchard , et al.
EULAR, Jun 2019, Madrid, Spain
Communication dans un congrès hal-02152564v1
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A robust enzyme-linked immunosorbent assay to measure serum ramucirumab concentrations

Celine Desvignes , David Ternant , Thierry Lecomte , Astrid Lièvre , Marc Ohresser , et al.
Bioanalysis, 2021, 13 (7), pp.565-574. ⟨10.4155/bio-2020-0199⟩
Article dans une revue inserm-03186974v1
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Monoclonal Antibodies Targeting the IL-17/IL-17RA Axis: An Opportunity to Improve the Efficiency of Anti-VEGF Therapy in Fighting Metastatic Colorectal Cancer?

Sajida Ibrahim , Alban Girault , Marc Ohresser , Emilie Lereclus , Gilles Paintaud , et al.
Clinical Colorectal Cancer, 2017, ⟨10.1016/j.clcc.2017.10.003⟩
Article dans une revue inserm-01661759v1

Skin inflammatory response and efficacy of anti-epidermal growth factor receptor therapy in metastatic colorectal cancer (CUTACETUX)

David Tougeron , Sheik Emambux , Laure Favot , Thierry Lecomte , Ewa Wierzbicka-Hainaut , et al.
OncoImmunology, 2020, 9 (1), pp.1848058. ⟨10.1080/2162402X.2020.1848058⟩
Article dans une revue hal-03149030v1

Infliximab concentration is predictive of control of disease activity and maintenance of treatment in rheumatoid arthritis.

Lin D. Chu Miow , Emilie Ducourau , Denis Mulleman , P. Emond , Denis Ternant , et al.
Annual European Congress of Rheumatology, Paris, 11-14 June 2008., Jun 2008, PARIS, France. Suppl. II:177 (THU-0131)
Communication dans un congrès hal-00320106v1

Adalimumab trough serum levels and clinical response in a single-center cohort of inflammatory bowel disease patients: Can trough serum levels serve as a predictor for Future Loss of Response?

K. Karmiris , Gilles Paintaud , Danielle Degenne , M. Ferrante , Anne-Claire Duveau , et al.
Digestives Diseases Week San Diego 17-22 mai., May 2008, SAN DIEGO, United States. 134 (4, Supplement 1): A-68
Communication dans un congrès hal-00320142v1

Brief Report: Relationship Between Serum Infliximab Concentrations and Risk of Infections in Patients Treated for Spondyloarthritis

Theodora Bejan-Angoulvant , David Ternant , Fadela Daoued , Frédéric Medina , Louis Bernard , et al.
Arthritis & rheumatology, 2017, 69 (1), pp.108-113. ⟨10.1002/art.39841⟩
Article dans une revue hal-01980809v1

Development and validation of an enzyme-linked immunosorbent assay to measure adalimumab concentration

Celine Desvignes , Soujanya Edupuganti , François Darrouzain , Anne-Claire Duveau , Amy Loercher , et al.
Bioanalysis, 2015, 7 (10), pp.1253-1260. ⟨10.4155/bio.15.30⟩
Article dans une revue hal-02372930v1

An Enzyme-Linked Immunosorbent Assay to Study Bevacizumab Pharmacokinetics

David Ternant , Nicolas Ceze , Thierry Lecomte , Danielle Degenne , Anne-Claire Duveau , et al.
Ther. Drug Monit., 2010, 32 (5), pp.647-652
Article dans une revue hal-00616329v1

An enzyme-linked immunosorbent assay for therapeutic drug monitoring of cetuximab

D. Ternant , N. Ceze , F. Piller , D. Degenne , E. Dorval , et al.
Fundamental & Clinical Pharmacology, 2009, 23, pp.23-23
Article dans une revue hal-00616413v1

Therapeutic antibodies in ophthalmology Old is new again

Charlotte Magdelaine-Beuzelin , Coralie Pinault , Gilles Paintaud , Herve Watier
mAbs, 2010, 2 (2), pp.176-180. ⟨10.4161/mabs.2.2.11205⟩
Article dans une revue hal-00616362v1
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Pharmacokinetics of adalimumab in Crohn’s disease

David Ternant , Konstantinos Karmiris , Séverine Vermeire , Celine Desvignes , Nicolas Azzopardi , et al.
European Journal of Clinical Pharmacology, 2015, 71 (9), pp.1155-1157. ⟨10.1007/s00228-015-1892-1⟩
Article dans une revue hal-01769822v1

Aerosoltherapy for lung tumors using the monoclonal antibody cetuximab

Agnes Maillet , Laurent Guilleminault , Nicolas Azzopardi , Jerome Montharu , Laurent Vecellio , et al.
Journal of Thoracic Oncology, 2009, 4 (9), pp.S600-S600
Article dans une revue hal-00616858v1
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A phase II randomised study of preoperative trastuzumab alone or combined with everolimus in patients with early HER2-positive breast cancer and predictive biomarkers (RADHER trial)

Mario Campone , Thomas Bachelot , Isabelle Treilleux , Barbara Pistilli , Julia Salleron , et al.
European Journal of Cancer, 2021, 158, pp.169-180. ⟨10.1016/j.ejca.2021.09.017⟩
Article dans une revue hal-03469622v1
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Long-term outcomes in patients with PET-predicted poor-responsive HER2-positive breast cancer treated with neoadjuvant bevacizumab added to trastuzumab and docetaxel: 5-year follow-up of the randomised Avataxher study

Benoit Coudert , Jean-Yves Pierga , Marie-Ange Mouret-Reynier , Kaldoun Kerrou , Jean-Marc Ferrero , et al.
EClinicalMedicine, 2020, 28, pp.100566. ⟨10.1016/j.eclinm.2020.100566⟩
Article dans une revue hal-03244169v1

Model-Based Therapeutic Drug Monitoring of Infliximab Using a Single Serum Trough Concentration

David Ternant , Christophe Passot , Alexandre Aubourg , Philippe Goupille , Celine Desvignes , et al.
Clinical Pharmacokinetics, 2018, 57 (9), pp.1173-1184. ⟨10.1007/s40262-017-0621-6⟩
Article dans une revue hal-02372850v1
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Influence of Antigen Mass on the Pharmacokinetics of Therapeutic Antibodies in Humans

David Ternant , Nicolas Azzopardi , William Raoul , Theodora Bejan-Angoulvant , Gilles Paintaud
Clinical Pharmacokinetics, In press, ⟨10.1007/s40262-018-0680-3⟩
Article dans une revue hal-01821717v1

Le Centre Pilote de suivi Biologique des Anticorps thérapeutiques (CePiBac) du CHU de Tours.

Gilles Paintaud
6ème Réunion des Pharmacologues de l'Ouest. Mosnes, Jun 2008, MOSNES, France
Communication dans un congrès hal-00319009v1

Development of anti-infliximab antibodies increases infliximab clearance in chronic Inflammatory Bowel Diseases.

David Ternant , Alexandre Aubourg , Charlotte Magdelaine-Beuzelin , Danielle Degenne , Hervé Watier , et al.
Immunogenicity for Biologics 2008, IBC Congress, Bâle (Suisse), 5-6 février., Feb 2008, BALE, Switzerland
Communication dans un congrès hal-00320459v1

Rituximab-related late-onset neutropenia in a severe rheumatoid arthritis patient (case report).

H. Marotte , Gilles Paintaud , Hervé Watier , P. Miossec
Annals of the Rheumatic Diseases, 2008, 67, pp.893-894
Article dans une revue hal-00318083v1
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Intra-tracheal amikacin spray delivery in healthy mechanically ventilated piglets

Antoine Guillon , François Darrouzain , Nathalie Heuzé-Vourc'H , Antoine Petitcollin , Céline Barc , et al.
Pulmonary Pharmacology and Therapeutics, 2019, 57, pp.101807. ⟨10.1016/j.pupt.2019.101807⟩
Article dans une revue hal-02526680v1

Pharmacokinetics (PK) of mAbs

Gilles Paintaud
Médecine/Sciences, 2009, 25 (12), pp.1057-1062
Article dans une revue hal-00616817v1

Cetuximab pharmacokinetics influences progression-free survival of metastatic colorectal cancer patients

Nicolas Azzopardi , Therry Lecomte , David Ternant , Michele Boisdron-Celle , Friedrich Piller , et al.
Fundamental & Clinical Pharmacology, 2011, 25, pp.34-34
Article dans une revue hal-00616314v1