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SARS-CoV-2 E and 3a proteins are inducers of pannexin currents

 Barbara Oliveira Mendes , Malak Alameh , Beatrice Ollivier , Jerome Montnach , Nicolas Bidere , et al.
2022
Pré-publication, Document de travail hal-03823805v1
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Editorial: Molecular Mechanisms of Voltage-Gating in Ion Channels

 Gildas Loussouarn , Mounir Tarek
Frontiers in Pharmacology, 2021, 12, ⟨10.3389/fphar.2021.768153⟩
Article dans une revue hal-03348830v1
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Computer modeling of whole-cell voltage-clamp analyses to delineate guidelines for good practice of manual and automated patch-clamp

 Jérôme Montnach , Maxime Lorenzini , Adrien Lesage , Isabelle Simon , Sébastien Nicolas , et al.
Scientific Reports, 2021, ⟨10.1038/s41598-021-82077-8⟩
Article dans une revue hal-03160824v1
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A functional network of highly pure enteric neurons in a dish

 Martial Caillaud , Morgane Le Dréan , Adrien De-Guilhem-De-Lataillade , Catherine Le Berre-Scoul , Jérôme Montnach , et al.
Frontiers in Neuroscience, 2023, 16, pp.1062253. ⟨10.3389/fnins.2022.1062253⟩
Article dans une revue hal-04163542v1
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Arrhythmias precede cardiomyopathy and remodeling of Ca2+ handling proteins in a novel model of long QT syndrome

 Jérôme Montnach , Franck Chizelle , Nadjet Belbachir , Claire Castro , Linwei Li , et al.
Journal of Molecular and Cellular Cardiology, 2018, 123, pp.13 - 25. ⟨10.1016/j.yjmcc.2018.08.019⟩
Article dans une revue hal-01900579v1
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The Integrative Approach to Study of the Structure and Functions of Cardiac Voltage-Dependent Ion Channels

 Juila G Kacher , Maria G Karlova , Grigory S Glukhov , Han Zhang , Elena V Zaklyazminskaya , et al.
2021
Pré-publication, Document de travail hal-03350105v1

Studying Kv Channels Function using Computational Methods

 Audrey Deyawe , Marina A. Kasimova , Lucie Delemotte , Gildas Loussouarn , Mounir Tarek
Methods in Molecular Biology, 2018, Equipe IIa, 1684, pp.321--341. ⟨10.1007/978-1-4939-7362-0_24⟩
Article dans une revue hal-01833334v1
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Dysfunction of the Voltage-Gated K+ Channel beta 2 Subunit in a Familial Case of Brugada Syndrome

 Vincent Portero , Solena Le Scouarnec , Zeineb Es-Salah-Lamoureux , Sophie Burel , Jean-Baptiste Gourraud , et al.
Journal of the American Heart Association, 2016, 5 (6), pp.e003122. ⟨10.1161/JAHA.115.003122⟩
Article dans une revue hal-01414464v1

KCNE1-KCNQ1 osmoregulation by interaction of phosphatidylinositol-4,5-bisphosphate with Mg2+ and polyamines.

 Julien Piron , Frank S Choveau , Mohammed Yassine Amarouch , Nicolas Rodriguez , Flavien Charpentier , et al.
The Journal of Physiology, 2010, 588 ((Pt 18)), pp.3471-83. ⟨10.1113/jphysiol.2010.195313⟩
Article dans une revue hal-00651470v1

Marine n-3 PUFAs modulate IKs gating, channel expression, and location in membrane microdomains

 Cristina Moreno , Alicia de La Cruz , Anna Oliveras , Sanjay R. Kharche , Miriam Guizy , et al.
Cardiovascular Research, 2015, Equipe 1, 105 (2), pp.223--232. ⟨10.1093/cvr/cvu250⟩
Article dans une revue hal-01830579v1
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A long QT mutation substitutes cholesterol for phosphatidylinositol-4,5-bisphosphate in KCNQ1 channel regulation

 F. C. Coyan , F. Abderemane-Ali , M. Y. Amarouch , J. Piron , J. Mordel , et al.
PLoS ONE, 2014, 9 (3), pp.e93255. ⟨10.1371/journal.pone.0093255⟩
Article dans une revue hal-02363771v1
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Disruption of a Conservative Motif in the C-Terminal Loop of the KCNQ1 Channel Causes LQT Syndrome

 Maria Karlova , Denis Abramochkin , Ksenia Pustovit , Tatiana Nesterova , Valery Novoseletsky , et al.
International Journal of Molecular Sciences, 2022, 23 (14), pp.7953. ⟨10.3390/ijms23147953⟩
Article dans une revue hal-03797267v1
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Predicting hERG repolarization power at 37°C from recordings at room temperature

 Barbara B R Oliveira‐mendes , Malak Alameh , Jérôme Montnach , Béatrice Ollivier , Solène Gibaud , et al.
Clinical and Translational Medicine, 2023, 13 (5), ⟨10.1002/ctm2.1266⟩
Article dans une revue hal-04109461v1
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hERG S4-S5 linker acts as a voltage-dependent ligand that binds to the activation gate and locks it in a closed state

 Olfat A. Malak , Zeineb Es-Salah-Lamoureux , Gildas Loussouarn
Scientific Reports, 2017, 7 (1), pp.113. ⟨10.1038/s41598-017-00155-2⟩
Article dans une revue hal-01832145v1
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Toward Personalized Medicine: Using Cardiomyocytes Differentiated From Urine-Derived Pluripotent Stem Cells to Recapitulate Electrophysiological Characteristics of Type 2 Long QT Syndrome

 Mariam Jouni , Karim Si-Tayeb , Zeineb Es-Salah-Lamoureux , Xenia Latypova , Benoite Champon , et al.
Journal of the American Heart Association, 2015, pp.e002159. ⟨10.1161/JAHA.115.002159⟩
Article dans une revue inserm-01199430v1
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SARS-CoV-2 E and 3a Proteins Are Inducers of Pannexin Currents

 Barbara Oliveira-Mendes , Malak Alameh , Béatrice Ollivier , Jérôme Montnach , Nicolas Bidère , et al.
Cells, 2023, 12 (11), pp.1474. ⟨10.3390/cells12111474⟩
Article dans une revue hal-04234657v1
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Human model of IRX5 mutations reveals key role for this transcription factor in ventricular conduction

 Zeina R Al Sayed , Robin Canac , Bastien Cimarosti , Carine Bonnard , Jean-Baptiste Gourraud , et al.
Cardiovascular Research, 2021, 117 (9), pp.2092-2107. ⟨10.1093/cvr/cvaa259⟩
Article dans une revue inserm-02934863v2
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Modeling sudden cardiac death risks factors in COVID-19 patients -the hydroxychloroquine and azithromycin case

 Jérôme Montnach , Isabelle Baró , Flavien Charpentier , Michel de Waard , Gildas Loussouarn
EP-Europace, 2021, ⟨10.1093/europace/euab043⟩
Article dans une revue hal-03349858v1
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A consistent arrhythmogenic trait in Brugada syndrome cellular phenotype

 Zeina Al Sayed , Mariam Jouni , Jean‐baptiste Gourraud , Nadjet Belbachir , Julien Barc , et al.
Clinical and Translational Medicine, 2021, 11 (6), pp.e413. ⟨10.1002/ctm2.413⟩
Article dans une revue inserm-04136802v2
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Voltage-dependent activation in EAG channels follows a ligand-receptor rather than a mechanical-lever mechanism

 Olfat A Malak , Grigory S Gluhov , Anastasia V Grizel , Kseniya S Kudryashova , Olga Sokolova , et al.
Journal of Biological Chemistry, 2019, ⟨10.1074/jbc.RA119.007626⟩
Article dans une revue hal-02104954v1
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Up-regulation of voltage-gated sodium channels by peptides mimicking S4-S5 linkers reveals a variation of the ligand-receptor mechanism

 Olfat Malak , Fayal Abderemane-Ali , Yue Wei , Fabien C Coyan , Gilyane Pontus , et al.
Scientific Reports, 2020, 10, pp.5852. ⟨10.1038/s41598-020-62615-6⟩
Article dans une revue hal-02531094v1
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Multifocal Ectopic Purkinje-Related Premature Contractions: A New SCN5A-Related Cardiac Channelopathy.

 Gabriel Laurent , Samuel Saal , Mohamed Yassine Amarouch , Delphine M. Béziau , Roos F. J. Marsman , et al.
Journal of the American College of Cardiology, 2012, 60 (2), pp.144-56. ⟨10.1016/j.jacc.2012.02.052⟩
Article dans une revue inserm-00719034v1
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Detergent-free solubilization of human Kv channels expressed in mammalian cells

 M G Karlova , N Voskoboynikova , G S Gluhov , D Abramochkin , O A Malak , et al.
Chemistry and Physics of Lipids, 2019, ⟨10.1016/j.chemphyslip.2019.01.013⟩
Article dans une revue hal-02109357v1
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Nav1.2 and BK channel interaction shapes the action potential in the axon initial segment

 Luiza Filipis , Laila Ananda Blömer , Jérôme Montnach , Gildas Loussouarn , Michel de Waard , et al.
The Journal of Physiology, 2023, 601 (10), pp.1957-1979. ⟨10.1113/JP283801⟩
Article dans une revue hal-04235449v1
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A need for exhaustive and standardized characterization of ion channels activity. The case of KV11.1

 Malak Alameh , Barbara Ribeiro Oliveira-Mendes , Florence Kyndt , Jordan Rivron , Isabelle Denjoy , et al.
Frontiers in Physiology, 2023, 14, ⟨10.3389/fphys.2023.1132533⟩
Article dans une revue hal-04235353v1
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A standardised hERG phenotyping pipeline to evaluate KCNH2 genetic variant pathogenicity

 Barbara Oliveira-Mendes , Sylvain Feliciangeli , Mélissa Ménard , Frank Chatelain , Malak Alameh , et al.
Clinical and Translational Medicine, 2021, 11 (11), ⟨10.1002/ctm2.609⟩
Article dans une revue hal-03797256v1

Phosphatidylinositol-4,5-bisphosphate (PIP(2)) stabilizes the open pore conformation of the Kv11.1 (hERG) channel.

 Nicolas Rodriguez , Mohamed Yassine Amarouch , Jérôme Montnach , Julien Piron , Alain J Labro , et al.
Biophysical Journal, 2010, 99 ((4)), pp.1110-8. ⟨10.1016/j.bpj.2010.06.013⟩
Article dans une revue hal-00651490v1
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Functional Impact of BeKm-1, a High-Affinity hERG Blocker, on Cardiomyocytes Derived from Human-Induced Pluripotent Stem Cells

 Stephan de Waard , Jérôme Montnach , Barbara Ribeiro , Sébastien Nicolas , Virginie Forest , et al.
International Journal of Molecular Sciences, 2020, 2020, ⟨10.3390/ijms21197167⟩
Article dans une revue hal-02951542v1

KCNQ1 channels voltage dependence through a voltage-dependent binding of the S4-S5 linker to the pore domain.

 Frank S Choveau , Nicolas Rodriguez , Fayal Abderemane Ali , Alain J Labro , Thierry Rose , et al.
Journal of Biological Chemistry, 2011, 286 (1), pp.707-16. ⟨10.1074/jbc.M110.146324⟩
Article dans une revue hal-00642776v1

C-terminal phosphorylation of NaV1.5 impairs FGF13-dependent regulation of channel inactivation

 Sophie Burel , Fabien C. Coyan , Maxime Lorenzini , Matthew R. Meyer , Cheryl F. Lichti , et al.
Journal of Biological Chemistry, 2017, Equipe IIa, 292 (42), pp.17431--17448. ⟨10.1074/jbc.M117.787788⟩
Article dans une revue hal-01832134v1
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