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Coupe le cordon, vole de tes propres ailes !
Erwan Mortier
,
Fella Tamzalit
,
Yannick Jacques
,
Sébastien Morisseau
Article dans une revue
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NK Cell Hyporesponsiveness: More Is Not Always Better
Marie Frutoso
,
Erwan Mortier
Article dans une revue
inserm-02289319v1
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Natural, Proteolytic Release of a Soluble Form of Human IL-15 Receptor a-Chain That Behaves as a Specific, High Affinity IL-15 Antagonist
Erwan Mortier
,
Jerome Bernard
,
Ariane Plet
,
Yannick Jacques
Journal of Immunology, 2004, 173, pp.1681 - 1688
Article dans une revue
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Macrophage-and Dendritic-Cell-Derived Interleukin-15 Receptor Alpha Supports Homeostasis of Distinct CD8+ T Cell Subsets
Erwan Mortier
,
Rommel Advincula
,
Leesun Kim
,
Stephen Chmura
,
Julio Barrera
,
et al.
Article dans une revue
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Editorial: Modulating Cytokines as Treatment for Autoimmune Diseases and Cancer
Erwan Mortier
,
Averil Ma
,
Barbara A Malynn
,
Markus F Neurath
Article dans une revue
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Homeostatic MyD88-dependent signals cause lethal inflammation in the absence of A20
Emre E Turer
,
Rita M Tavares
,
Erwan Mortier
,
Osamu Hitotsumatsu
,
Rommel Advincula
,
et al.
Article dans une revue
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Syndecan-1 regulates the biological activities of interleukin-34
Aude Segaliny
,
Régis Brion
,
Erwan Mortier
,
Mike Maillasson
,
Michel Chérel
,
et al.
Article dans une revue
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Interleukin-15 and Its Soluble Receptor Mediate the Response to Infliximab in Patients With Crohn's Disease
Grégory Bouchaud
,
Erwan Mortier
,
Mathurin Flamant
,
Isabelle Barbieux
,
Ariane Plet
,
et al.
Article dans une revue
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Cutting Edge: Differential Fine-Tuning of IL-2- and IL-15- Dependent Functions by targeting their Common IL-2/15Rβ/γc Receptor
Dihia Meghnem
,
Sébastien Morisseau
,
Marie Frutoso
,
Kilian Trillet
,
Mike Maillasson
,
et al.
Article dans une revue
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Le renouveau de l'interleukine 2 : Modèle revisité et nouvelles applications thérapeutiques
Yannick Jacques
,
Erwan Mortier
Article dans une revue
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The Exon-3-Encoded Domain of IL-15Rα Contributes to IL-15 High-Affinity Binding and Is Crucial for the IL-15 Antagonistic Effect of Soluble IL-15Rα
Grégory Bouchaud
,
Laure Garrigue-Antar
,
Véronique Solé
,
Agnès Quéméner
,
Yvan Boublik
,
et al.
Article dans une revue
istex
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Reversible DNA Hypermethylation of the Interleukin-15 (IL-15) Promoter Induces IL-15 Expression, Drives the Pathogenesis of T-Cell Large Granular Lymphocytic Leukemia and Provides a Potential Therapeutic Approach Using 5-Azacitidine
Jonathan Brammer
,
Amy Boles
,
Anthony Mansour
,
Aharon Freud
,
Monique Mathé-Allainmat
,
et al.
Communication dans un congrès
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Emergence of NK Cell Hyporesponsiveness after Two IL-15 Stimulation Cycles
Marie Frutoso
,
Sébastien Morisseau
,
Fella Tamzalit
,
Agnès Quéméner
,
Dihia Meghnem
,
et al.
Article dans une revue
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Different dynamics of IL-15R activation following IL-15 cis-or trans-presentation
Harmonie Perdreau
,
Erwan Mortier
,
Grégory Bouchaud
,
Véronique Sole
,
Yvan Boublik
,
et al.
Article dans une revue
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IL-15.IL-15Rα complex shedding following trans-presentation is essential for the survival of IL-15 responding NK and T cells
Fella Tamzalit
,
Isabelle Barbieux
,
Ariane Plet
,
Julie Heim
,
Steven Nedellec
,
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (23), pp.8565. ⟨10.1073/pnas.1405514111⟩
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Regulation of CD4+NKG2D+ Th1 Cells in Patients with Metastatic Melanoma Treated with Sorafenib: Role of IL-15Rα and NKG2D Triggering
Ana I Romero
,
Nathalie Chaput
,
Vichnou Poirier-Colame
,
Sylvie Rusakiewicz
,
Nicolas Jacquelot
,
et al.
Article dans une revue
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IL-15Rα chaperones IL-15 to stable dendritic cell membrane complexes that activate NK cells via trans presentation
Erwan Mortier
,
Tammy Woo
,
Rommel Advincula
,
Sara Gozalo
,
Averil Ma
Article dans une revue
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IL-15 trans-presentation promotes human NK cell development and differentiation in vivo
Nicholas D Huntington
,
Nicolas Legrand
,
Nuno L. Alves
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Barbara Jaron
,
Kees Weijer
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et al.
Article dans une revue
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Discovery of a Small-Molecule Inhibitor of Interleukin 15: Pharmacophore-Based Virtual Screening and Hit Optimization
Agnès Quéméner
,
Mike Maillasson
,
Laurence Arzel
,
Benoit Sicard
,
Romy Vomiandry
,
et al.
Article dans une revue
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IL-15Rα membrane-anchorage either in cis or in trans is required for stabilization of IL-15 and optimal signaling
Agnès Quéméner
,
Sébastien Morisseau
,
Rui P Sousa
,
Kilian Trillet
,
Mike Maillasson
,
et al.
Article dans une revue
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Counteracting Interleukin-15 to Elucidate Its Modes of Action in Physiology and Pathology
Erwan Mortier
,
Mike Maillasson
,
Agnès Quéméner
Article dans une revue
inserm-03948405v1
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Identification of an Interleukin-15 α Receptor-binding Site on Human Interleukin-15
Jérôme Bernard
,
Catherine Harb
,
Erwan Mortier
,
Agnès Quéméner
,
Rob H Meloen
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et al.
Article dans une revue
inserm-02442410v1
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Docking of Human Interleukin-15 to its Specific Receptor α Chain: Correlation Between Molecular Modeling and Mutagenesis Experimental Data
Agnès Quéméner
,
Jérôme Bernard
,
Erwan Mortier
,
Ariane Plet
,
Yannick Jacques
,
et al.
Proteins - Structure, Function and Bioinformatics, 2006, 65 (3), pp.623
Article dans une revue
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MUTATED INTERLEUKIN-34 (IL-34) POLYPEPTIDES AND USES THEREOF IN THERAPY
Carole Guillonneau
,
Ignacio Anegon
,
Erwan Mortier
,
Agnès Quéméner
France, Patent n° : WO2020148338. 2020
Brevet
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BTN2A, a New Immune-Checkpoint Targeting Vg9Vd2 T Cell Cytotoxicity
Carla Cano
,
Christine Pasero
,
Aude de Gassart
,
René Hoet
,
Emmanuel Scotet
,
et al.
Communication dans un congrès
inserm-02991780v1
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Interleukin-15 and cancer: some solved and many unsolved questions
Piera Filomena Fiore
,
Sabina Di Matteo
,
Nicola Tumino
,
Francesca Romana Mariotti
,
Gabriella Pietra
,
et al.
Journal for Immunotherapy of Cancer, 2020
Article dans une revue
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MODULATING CYTOKINES AS TREATMENT FOR AUTOIMMUNE DISEASES AND CANCER
Erwan Mortier
,
Averil Ma
,
Barbara A Malynn
,
Markus F Neurath
Ouvrages
inserm-03079706v1
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Mechanistic and Structural Insights on the IL-15 System through Molecular Dynamics Simulations
Rui P Sousa
,
Adèle Laurent
,
Agnès Quéméner
,
Erwan Mortier
,
Jean-Yves Le Questel
Article dans une revue
inserm-02289307v1
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The Soluble α Chain of Interleukin-15 Receptor: A Proinflammatory Molecule Associated with Tumor Progression in Head and Neck Cancer
Cécile Badoual
,
Grégory Bouchaud
,
Nour El Houda Agueznay
,
Erwan Mortier
,
Stéphane Hans
,
et al.
Article dans une revue
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